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Int. J. Mol. Sci. 2003, 4(6), 371-378;

C- versus O-Arylation of an Enol-Lactone Using Potassium tert-butoxide

INRS-Institut Armand-Frappier, 531 Boul. des Prairies, Laval, Québec, Canada
Laboratoire de Chimie Organique Hétérocyclique, Faculté des Sciences, Université Mohamed V, Rabat, Marocco
Author to whom correspondence should be addressed.
Received: 31 October 2002 / Accepted: 6 March 2003 / Published: 31 May 2003
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The use of potassium tert-butoxide as the base in arylation reactions of an enollactone with a series of benzyl halides was explored. Our work demonstrates that the ratio of C-arylation to O-arylation varies with the substitution pattern of the aryl halide.
Keywords: Arylation; Enol-lactone; Potassium tert-butoxide Arylation; Enol-lactone; Potassium tert-butoxide
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Ibrahimi, S.; Sauvé, G.; Essassi, E.M. C- versus O-Arylation of an Enol-Lactone Using Potassium tert-butoxide. Int. J. Mol. Sci. 2003, 4, 371-378.

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