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International Journal of Molecular Sciences
  • Correction
  • Open Access

10 September 2025

Correction: Shi et al. The Anaesthetics Isoflurane and Xenon Reverse the Synaptotoxic Effects of Aβ1–42 on Megf10-Dependent Astrocytic Synapse Elimination and Spine Density in Ex Vivo Hippocampal Brain Slices. Int. J. Mol. Sci. 2023, 24, 912

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1
Department of Anesthesiology and Intensive Care, Klinikum Rechts der Isar, Ismaningerstraße 22, 81675 Munich, Germany
2
School of Biomedical Sciences, The University of Queensland, St. Lucia, QLD 4072, Australia
3
German Center for Neurodegenerative Diseases, Feodor-Lynen-Straße 23, 81377 Munich, Germany
4
Center for Neuropathology and Prion Research, Feodor-Lynen-Straße 23, 81377 Munich, Germany
This article belongs to the Section Molecular Toxicology
In the original publication [1], inadvertent errors were present in Figures 1A and 1C. Specifically, the control images in both Figures 1A and 1C, as well as the xe-60 image in Figure 1C, were duplicated unintentionally. These duplications resulted from an oversight during the final figure assembly. The correct Figure 1 is shown below.
Figure 1. (A,C) show representative dendrites from the control group and the isoflurane (Iso)/xenon (Xe) treated groups, at treatment and post wash out (60/90 min) of gas, respectively. Scale bar = 5 μm. Dendrites were analyzed from brain slices of GFP-M mice. (B,D) left graphs show both Iso and Xe reduced the DSD in the dentate gyrus of hippocampus (p = 0.0201 for iso, and p = 0.0244 for Xe, Mann–Whitney U test). (B,D) right graphs show that after 60 mins the reduction of DSD caused by Xe was reversed (p = 0.3441 Mann–Whitney U test), but not for Iso after 90 mins (p = 0.0297, Mann–Whitney U test). Error bars in all graphs indicate the means +/− SDs. Every data point in the scatter plots represents the mean spine density from 8–10 dendrites per one animal (n = 8–13). Dendrites that were 15 µm away from their respective cell’s soma were chosen for these analyses. Black horizontal bars below the * indicate a significant difference (p < 0.05) between the groups.
The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Reference

  1. Shi, D.; Wong, J.K.Y.; Zhu, K.; Noakes, P.G.; Rammes, G. The Anaesthetics Isoflurane and Xenon Reverse the Synaptotoxic Effects of Aβ1–42 on Megf10-Dependent Astrocytic Synapse Elimination and Spine Density in Ex Vivo Hippocampal Brain Slices. Int. J. Mol. Sci. 2023, 24, 912. [Google Scholar] [CrossRef] [PubMed]
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