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Suggestions on the Contribution of Methyl Eugenol and Eugenol to Bay Laurel (Laurus nobilis L.) Essential Oil Preservative Activity through Radical Scavenging

1
Laboratory of Food Chemistry and Technology (LFCT), School of Chemistry, Aristotle University of Thessaloniki (AUTh), 57001 Thessaloniki, Greece
2
Natural Products Research Center of Excellence (NatPro-AUTH), Center for Interdisciplinary Research and Innovation (CIRI-AUTH), 57001 Thessaloniki, Greece
*
Author to whom correspondence should be addressed.
Academic Editor: Ericsson Coy-Barrera
Molecules 2021, 26(8), 2342; https://doi.org/10.3390/molecules26082342
Received: 16 March 2021 / Revised: 11 April 2021 / Accepted: 15 April 2021 / Published: 17 April 2021
(This article belongs to the Special Issue Trends in Natural Products Research in the Mediterranean Region)
The present study examined the radical scavenging potential of the two benzene derivatives found in the bay laurel essential oil (EO), namely methyl eugenol (MEug) and eugenol (Eug), theoretically and experimentally to make suggestions on their contribution to the EO preservative activity through such a mechanism. Calculation of appropriate molecular indices widely used to characterize chain-breaking antioxidants was carried out in the gas and liquid phases (n-hexane, n-octanol, methanol, water). Experimental evidence was based on the DPPH scavenging assay applied to pure compounds and a set of bay laurel EOs chemically characterized with GC-MS/FID. Theoretical calculations suggested that the preservative properties of both compounds could be exerted through a radical scavenging mechanism via hydrogen atom donation. Eug was predicted to be of superior efficiency in line with experimental findings. Pearson correlation and partial least square regression analyses of the EO antioxidant activity values vs. % composition of individual volatiles indicated the positive contribution of both compounds to the radical scavenging activity of bay laurel EOs. Eug, despite its low content in bay laurel EOs, was found to influence the most the radical scavenging activity of the latter. View Full-Text
Keywords: essential oil; food preservatives; DFT; methyl eugenol; eugenol; bay laurel; radical scavenging; Laurus nobilis; structure-activity relationship essential oil; food preservatives; DFT; methyl eugenol; eugenol; bay laurel; radical scavenging; Laurus nobilis; structure-activity relationship
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MDPI and ACS Style

Nenadis, N.; Papapostolou, M.; Tsimidou, M.Z. Suggestions on the Contribution of Methyl Eugenol and Eugenol to Bay Laurel (Laurus nobilis L.) Essential Oil Preservative Activity through Radical Scavenging. Molecules 2021, 26, 2342. https://doi.org/10.3390/molecules26082342

AMA Style

Nenadis N, Papapostolou M, Tsimidou MZ. Suggestions on the Contribution of Methyl Eugenol and Eugenol to Bay Laurel (Laurus nobilis L.) Essential Oil Preservative Activity through Radical Scavenging. Molecules. 2021; 26(8):2342. https://doi.org/10.3390/molecules26082342

Chicago/Turabian Style

Nenadis, Nikolaos, Maria Papapostolou, and Maria Z. Tsimidou 2021. "Suggestions on the Contribution of Methyl Eugenol and Eugenol to Bay Laurel (Laurus nobilis L.) Essential Oil Preservative Activity through Radical Scavenging" Molecules 26, no. 8: 2342. https://doi.org/10.3390/molecules26082342

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