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Review

Advances in Pyranopyrazole Scaffolds’ Syntheses Using Sustainable Catalysts—A Review

1
Department of Chemistry, GITAM Institute of Sciences, GITAM University, Visakhapatnam 530045, India
2
Department of Chemistry, GITAM School of Science, Bengaluru Campus, GITAM University, Karnataka 561203, India
3
School of Chemistry & Physics, Westville Campus, University of KwaZulu-Natal, Chiltern Hills, Durban 4000, South Africa
*
Author to whom correspondence should be addressed.
Academic Editor: Sylvain Caillol
Molecules 2021, 26(11), 3270; https://doi.org/10.3390/molecules26113270
Received: 29 April 2021 / Revised: 23 May 2021 / Accepted: 26 May 2021 / Published: 28 May 2021
Heterogeneous catalysis plays a crucial role in many chemical processes, including advanced organic preparations and the design and synthesis of new organic moieties. Efficient and sustainable catalysts are vital to ecological and fiscal viability. This is why green multicomponent reaction (MCR) approaches have gained prominence. Owing to a broad range of pharmacological applications, pyranopyrazole syntheses (through the one-pot strategy, employing sustainable heterogeneous catalysts) have received immense attention. This review aimed to emphasise recent developments in synthesising nitrogen-based fused heterocyclic ring frameworks, exploring diverse recyclable catalysts. The article focused on the synthetic protocols used between 2010 and 2020 using different single, bi- and tri-metallic materials and nanocomposites as reusable catalysts. This review designated the catalysts’ efficacy and activity in product yields, reaction time, and reusability. The MCR green methodologies (in conjunction with recyclable catalyst materials) proved eco-friendly and ideal, with a broad scope that could feasibly lead to advancements in organic synthesis. View Full-Text
Keywords: multicomponent reactions; heterogeneous catalysts; pyranopyrazoles; one-pot process; green protocols multicomponent reactions; heterogeneous catalysts; pyranopyrazoles; one-pot process; green protocols
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MDPI and ACS Style

Ganta, R.K.; Kerru, N.; Maddila, S.; Jonnalagadda, S.B. Advances in Pyranopyrazole Scaffolds’ Syntheses Using Sustainable Catalysts—A Review. Molecules 2021, 26, 3270. https://doi.org/10.3390/molecules26113270

AMA Style

Ganta RK, Kerru N, Maddila S, Jonnalagadda SB. Advances in Pyranopyrazole Scaffolds’ Syntheses Using Sustainable Catalysts—A Review. Molecules. 2021; 26(11):3270. https://doi.org/10.3390/molecules26113270

Chicago/Turabian Style

Ganta, Ravi K., Nagaraju Kerru, Suresh Maddila, and Sreekantha B. Jonnalagadda 2021. "Advances in Pyranopyrazole Scaffolds’ Syntheses Using Sustainable Catalysts—A Review" Molecules 26, no. 11: 3270. https://doi.org/10.3390/molecules26113270

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