Novel and Efficient Synthesis of N,N-Dialkylaminoand O-alkylphenyl-2-(1-alkyl/phenyl-2-oxopropylidene) Phosphonohydrazido Oximes - Potential Marine Fish Toxin Analogues. Part 2
Abstract
:Introduction
Result and Discussion
Entry | R | R1 | Reaction time (h) | 31P-NMR b | m. p. (0C) | Yield c (%) |
---|---|---|---|---|---|---|
4a | N(C2H5)2 | CH3 | 3.0 | 22.55 | 154 | 81 |
4b | N(C3H7)2 | CH3 | 3.2 | 23.09 | 158 | 85 |
4c | N(C3H7)2 | C6H5 | 3.6 | 21.92 | 165 | 79 |
4d | N(C4H9)2 | CH3 | 3.2 | 21.75 | 142 | 86 |
4e | N(C4H9)2 | C6H5 | 4.2 | 21.63 | 178 | 93 |
4f | N( iC4H9)2 | CH3 | 4.3 | 20.88 | 180 | 76 |
4g | N( iC4H9)2 | C6H5 | 4.5 | 20.73 | 193 | 72 |
4h | OC3H7 | CH3 | 3.0 | 17.67 | 152 | 87 |
4i | OC3H7 | C6H5 | 3.1 | 17.27 | 155 | 74 |
4j | OiC3H7 | CH3 | 3.3 | 17.05 | 139 | 82 |
4k | OiC3H7 | C6H5 | 3.3 | 17.13 | 123 | 78 |
4l | OC4H9 | CH3 | 3.1 | 17.41 | 154 | 73 |
4m | OiC4H9 | C6H5 | 3.5 | 17.10 | 158 | 85 |
4n | OC5H11 | CH3 | 3.8 | 17.58 | 148 | 86 |
4o | OC5H11 | C6H5 | 4.0 | 17.13 | 167 | 94 |
Conclusions
Experimental
General
General procedure for the preparation of compounds 4a-o: N,N-diethylaminophenyl-2-(1-methyl-2-oxopropylidene) phosphonohydrazido oxime (4a).
Acknowledgements
References and Notes
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Kumar, R.; Gupta, A.K.; Kaushik, M.P. Novel and Efficient Synthesis of N,N-Dialkylaminoand O-alkylphenyl-2-(1-alkyl/phenyl-2-oxopropylidene) Phosphonohydrazido Oximes - Potential Marine Fish Toxin Analogues. Part 2. Molecules 2007, 12, 1632-1640. https://doi.org/10.3390/12081632
Kumar R, Gupta AK, Kaushik MP. Novel and Efficient Synthesis of N,N-Dialkylaminoand O-alkylphenyl-2-(1-alkyl/phenyl-2-oxopropylidene) Phosphonohydrazido Oximes - Potential Marine Fish Toxin Analogues. Part 2. Molecules. 2007; 12(8):1632-1640. https://doi.org/10.3390/12081632
Chicago/Turabian StyleKumar, Rajesh, Arvind K. Gupta, and Mahabir P. Kaushik. 2007. "Novel and Efficient Synthesis of N,N-Dialkylaminoand O-alkylphenyl-2-(1-alkyl/phenyl-2-oxopropylidene) Phosphonohydrazido Oximes - Potential Marine Fish Toxin Analogues. Part 2" Molecules 12, no. 8: 1632-1640. https://doi.org/10.3390/12081632