Special Issue "Novel Drug Candidates for Anticancer Therapy: Design, Preliminary Evaluations, and Further Developments"


A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: 20 May 2015

Special Issue Editors

Guest Editor
Dr. Jean Jacques Vanden Eynde
Laboratory of Organic Chemistry (FS), University of Mons-UMONS, Place du parc, 23, 7000 Mons, Belgium
Website: http://www.umons.be
E-Mail: jean-jacques.vandeneynde@ex.umons.ac.be
Phone: + 32 65 352589
Interests: heterocycles; microwave-induced synthesis; medicinal chemistry; green chemistry

Guest Editor
Dr. Annie Mayence
Haute Ecole Provinciale de Hainaut-Condorcet, Place Albert-Elisabeth, 7330 Saint-Ghislain, Belgium
Website: http://www.condorcet.be
E-Mail: annie.mayence@condorcet.be
Phone: +3 265 335 2589
Interests: medicinal chemistry; analytical chemistry

Guest Editor
Dr. Tien L. Huang
Division of Basic and Pharmaceutical sciences, College of Pharmacy, Xavier University of Louisiana, 1 Drexel Drive, New Orleans, LA 70125, USA
Website: http://www.xula.edu
E-Mail: thuang@xula.edu
Phone: +1 504 520 7603
Interests: medicinal chemistry; organic chemistry; anti-opportunistic agents; anti-parasitic agents; prodrugs

Special Issue Information

Dear Colleagues,

Developing novel cancer therapeutics is essential for treating cancer, a complex, multi-factorial disease that is dreaded worldwide. Although significant advances have been made in recent years in preventing and treating cancer, the mortality rate is still unacceptably high. Many of the current chemotherapeutics are limited by significant side effects, unpredictable efficacies or acquired resistances. Recent discoveries concerning the pathogenesis and biology of cancer have unraveled new, strategic cellular targets for drug intervention. This has allowed the rational development of novel cancer therapeutics. For this Special Issue, we invite the submission of manuscripts that focus on the design, synthesis, evaluation, and further development of investigational agents (including natural products) as potential cancer chemotherapeutics.

Dr. Jean Jacques Vanden Eynde
Dr. Annie Mayence
Dr. Tien L. Huang
Guest Editors


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs).


  • anticancer activity
  • anticancer agents
  • antiproliferative effects
  • antitumor activity
  • apoptosis
  • cancer cells
  • chemotherapy
  • cytotoxicity
  • oncology
  • tumor cells

Published Papers (6 papers)

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Displaying article 1-6
p. 15918-15937
by , ,  and
Molecules 2014, 19(10), 15918-15937; doi:10.3390/molecules191015918
Received: 27 August 2014; in revised form: 22 September 2014 / Accepted: 24 September 2014 / Published: 2 October 2014
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p. 15361-15373
by  and
Molecules 2014, 19(10), 15361-15373; doi:10.3390/molecules191015361
Received: 30 July 2014; in revised form: 9 September 2014 / Accepted: 11 September 2014 / Published: 26 September 2014
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p. 14649-14666
by , , , , , ,  and
Molecules 2014, 19(9), 14649-14666; doi:10.3390/molecules190914649
Received: 15 July 2014; in revised form: 1 September 2014 / Accepted: 3 September 2014 / Published: 16 September 2014
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p. 13177-13187
by  and
Molecules 2014, 19(9), 13177-13187; doi:10.3390/molecules190913177
Received: 12 May 2014; in revised form: 9 July 2014 / Accepted: 15 July 2014 / Published: 26 August 2014
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p. 12099-12115
by , , , , , , ,  and
Molecules 2014, 19(8), 12099-12115; doi:10.3390/molecules190812099
Received: 5 June 2014; in revised form: 13 July 2014 / Accepted: 22 July 2014 / Published: 12 August 2014
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p. 5925-5939
by , ,  and
Molecules 2014, 19(5), 5925-5939; doi:10.3390/molecules19055925
Received: 14 March 2014; in revised form: 23 April 2014 / Accepted: 4 May 2014 / Published: 8 May 2014
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Last update: 16 October 2014

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