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Molecules 2015, 20(3), 4430-4449; doi:10.3390/molecules20034430

Development of Advanced Macrosphelides: Potent Anticancer Agents

College of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju daero, Jinju, Gyeongnam 660-701, Korea
Academic Editors: Jean Jacques and Vanden Eynde
Received: 4 February 2015 / Revised: 1 March 2015 / Accepted: 6 March 2015 / Published: 10 March 2015

Abstract

Synthetic approaches to macrosphelide derivatives, based on medicinal chemistry, are summarized. This review contains conventional medicinal chemistry approaches, combinatorial chemistry, fluorous tagging techniques and affinity chromatography preparation. In addition, advances in their apoptosis-inducing activities are also included. View Full-Text
Keywords: macrosphelides; medicinal chemistry; analogs macrosphelides; medicinal chemistry; analogs
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Paek, S.-M. Development of Advanced Macrosphelides: Potent Anticancer Agents. Molecules 2015, 20, 4430-4449.

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