Special Issue "Prodrugs"
Deadline for manuscript submissions: closed (20 January 2011)
Dr. Jean Jacques Vanden Eynde (Website)
Formerly head of the Department of Organic Chemistry (FS), University of Mons-UMONS, 7000 Mons, Belgium
Interests: heterocycles; microwave-induced synthesis; medicinal chemistry; green chemistry
Working in the field of medicinal chemistry is a daily challenge. One has to design novel structures, prepare substances, purify them (an often tedious task), and “finally”, the substances are screened. With luck, some promising candidates will emerge from one’s chemical libraries. Then one has to go back to the lab and try to improve the efficacy of one’s leads by introducing some subtle modifications in their skeleton. At that point, one may realizes that there is an excellent potential drug but, some of its physical or pharmacological properties will hinder its development. Hopefully, under such circumstances, one will be able to circumvent those problems by conceiving some prodrugs.
This Special Issue focuses on all kinds of efforts made in order to discover, characterize, and study substances that can be metabolized into active species. Bioconjugation, drug delivery methodologies, and other fields of research closely related to the prodrug approach will also be considered with great interest and pleasure.
Dr. Jean Jacques Vanden Eynde
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.