Special Issue "Prodrugs"

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A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: closed (20 January 2011)

Special Issue Editor

Guest Editor
Dr. Jean Jacques Vanden Eynde

Formerly head of the Department of Organic Chemistry (FS), University of Mons-UMONS, 7000 Mons, Belgium
Website: http://www.cilbiotech.be/jj
Interests: heterocycles; microwave-induced synthesis; medicinal chemistry; green chemistry

Special Issue Information

Dear Colleagues,

Working in the field of medicinal chemistry is a daily challenge. One has to design novel structures, prepare substances, purify them (an often tedious task), and “finally”, the substances are screened. With luck, some promising candidates will emerge from one’s chemical libraries. Then one has to go back to the lab and try to improve the efficacy of one’s leads by introducing some subtle modifications in their skeleton. At that point, one may realizes that there is an excellent potential drug but, some of its physical or pharmacological properties will hinder its development. Hopefully, under such circumstances, one will be able to circumvent those problems by conceiving some prodrugs.

This Special Issue focuses on all kinds of efforts made in order to discover, characterize, and study substances that can be metabolized into active species. Bioconjugation, drug delivery methodologies, and other fields of research closely related to the prodrug approach will also be considered with great interest and pleasure.

Dr. Jean Jacques Vanden Eynde
Guest Editor

Submission

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs).


Keywords

  • prodrugs
  • prodrug

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Published Papers (50 papers)

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p. 21346-21363
by , , , , , ,  and
Molecules 2015, 20(12), 21346-21363; doi:10.3390/molecules201219762
Received: 23 October 2015 / Revised: 18 November 2015 / Accepted: 19 November 2015 / Published: 1 December 2015
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(This article belongs to the Special Issue Prodrugs)
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p. 12623-12651
by  and
Molecules 2015, 20(7), 12623-12651; doi:10.3390/molecules200712623
Received: 29 May 2015 / Revised: 6 July 2015 / Accepted: 7 July 2015 / Published: 13 July 2015
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(This article belongs to the Special Issue Prodrugs)
p. 7292-7308
by ,  and
Molecules 2015, 20(4), 7292-7308; doi:10.3390/molecules20047292
Received: 12 March 2015 / Revised: 3 April 2015 / Accepted: 7 April 2015 / Published: 21 April 2015
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(This article belongs to the Special Issue Prodrugs)
p. 1210-1227
by  and
Molecules 2015, 20(1), 1210-1227; doi:10.3390/molecules20011210
Received: 18 November 2014 / Accepted: 8 January 2015 / Published: 13 January 2015
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(This article belongs to the Special Issue Prodrugs)
p. 20780-20807
by
Molecules 2014, 19(12), 20780-20807; doi:10.3390/molecules191220780
Received: 20 October 2014 / Revised: 3 December 2014 / Accepted: 4 December 2014 / Published: 12 December 2014
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(This article belongs to the Special Issue Prodrugs)
p. 19718-19731
by , , , , , , , ,  and
Molecules 2014, 19(12), 19718-19731; doi:10.3390/molecules191219718
Received: 29 October 2014 / Revised: 19 November 2014 / Accepted: 19 November 2014 / Published: 27 November 2014
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(This article belongs to the Special Issue Prodrugs)
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p. 19460-19470
by , , , ,  and
Molecules 2014, 19(12), 19460-19470; doi:10.3390/molecules191219460
Received: 6 October 2014 / Revised: 14 November 2014 / Accepted: 18 November 2014 / Published: 25 November 2014
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(This article belongs to the Special Issue Prodrugs)
p. 18057-18072
by , , , , , ,  and
Molecules 2014, 19(11), 18057-18072; doi:10.3390/molecules191118057
Received: 2 September 2014 / Revised: 29 October 2014 / Accepted: 29 October 2014 / Published: 5 November 2014
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p. 16656-16671
by  and
Molecules 2014, 19(10), 16656-16671; doi:10.3390/molecules191016656
Received: 31 August 2014 / Revised: 22 September 2014 / Accepted: 10 October 2014 / Published: 15 October 2014
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p. 16489-16505
by ,  and
Molecules 2014, 19(10), 16489-16505; doi:10.3390/molecules191016489
Received: 12 September 2014 / Revised: 7 October 2014 / Accepted: 8 October 2014 / Published: 14 October 2014
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(This article belongs to the Special Issue Prodrugs)
p. 16274-16290
by , , , , ,  and
Molecules 2014, 19(10), 16274-16290; doi:10.3390/molecules191016274
Received: 14 July 2014 / Revised: 9 September 2014 / Accepted: 24 September 2014 / Published: 10 October 2014
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(This article belongs to the Special Issue Prodrugs)
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p. 13251-13266
by , , , , , ,  and
Molecules 2014, 19(9), 13251-13266; doi:10.3390/molecules190913251
Received: 19 May 2014 / Revised: 17 July 2014 / Accepted: 7 August 2014 / Published: 28 August 2014
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p. 12559-12576
by , , , ,  and
Molecules 2014, 19(8), 12559-12576; doi:10.3390/molecules190812559
Received: 24 June 2014 / Revised: 1 August 2014 / Accepted: 11 August 2014 / Published: 19 August 2014
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p. 4660-4671
by , , , , ,  and
Molecules 2011, 16(6), 4660-4671; doi:10.3390/molecules16064660
Received: 15 March 2011 / Revised: 27 May 2011 / Accepted: 31 May 2011 / Published: 3 June 2011
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p. 4140-4164
by , , , , , ,  and
Molecules 2011, 16(5), 4140-4164; doi:10.3390/molecules16054140
Received: 3 February 2011 / Accepted: 3 May 2011 / Published: 19 May 2011
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p. 2658-2671
by , , , ,  and
Molecules 2011, 16(3), 2658-2671; doi:10.3390/molecules16032658
Received: 18 January 2011 / Revised: 16 March 2011 / Accepted: 21 March 2011 / Published: 23 March 2011
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p. 1888-1900
by , ,  and
Molecules 2011, 16(2), 1888-1900; doi:10.3390/molecules16021888
Received: 11 January 2011 / Revised: 25 January 2011 / Accepted: 17 February 2011 / Published: 22 February 2011
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p. 552-566
by ,  and
Molecules 2011, 16(1), 552-566; doi:10.3390/molecules16010552
Received: 22 November 2010 / Revised: 30 December 2010 / Accepted: 13 January 2011 / Published: 14 January 2011
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p. 175-189
by , , ,  and
Molecules 2011, 16(1), 175-189; doi:10.3390/molecules16010175
Received: 22 November 2010 / Revised: 24 December 2010 / Accepted: 28 December 2010 / Published: 29 December 2010
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p. 1232-1241
by , , , , , , , ,  and
Molecules 2010, 15(3), 1232-1241; doi:10.3390/molecules15031232
Received: 2 February 2010 / Revised: 2 March 2010 / Accepted: 3 March 2010 / Published: 3 March 2010
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p. 1242-1264
by , , ,  and
Molecules 2010, 15(3), 1242-1264; doi:10.3390/molecules15031242
Received: 8 February 2010 / Revised: 2 March 2010 / Accepted: 3 March 2010 / Published: 3 March 2010
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p. 842-856
by ,  and
Molecules 2010, 15(2), 842-856; doi:10.3390/molecules15020842
Received: 11 January 2010 / Revised: 30 January 2010 / Accepted: 3 February 2010 / Published: 5 February 2010
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(This article belongs to the Special Issue Prodrugs)
p. 5247-5280
by , ,  and
Molecules 2009, 14(12), 5247-5280; doi:10.3390/molecules14125247
Received: 9 October 2009 / Revised: 8 December 2009 / Accepted: 14 December 2009 / Published: 15 December 2009
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(This article belongs to the Special Issue Prodrugs)
p. 5017-5026
by , , , , , , ,  and
Molecules 2009, 14(12), 5017-5026; doi:10.3390/molecules14125017
Received: 30 September 2009 / Revised: 22 November 2009 / Accepted: 30 November 2009 / Published: 2 December 2009
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p. 4517-4545
by , , ,  and
Molecules 2009, 14(11), 4517-4545; doi:10.3390/molecules14114517
Received: 10 October 2009 / Revised: 3 November 2009 / Accepted: 5 November 2009 / Published: 10 November 2009
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p. 4231-4245
by ,  and
Molecules 2009, 14(10), 4231-4245; doi:10.3390/molecules14104231
Received: 18 September 2009 / Revised: 13 October 2009 / Accepted: 19 October 2009 / Published: 22 October 2009
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p. 3869-3880
by
Molecules 2009, 14(10), 3869-3880; doi:10.3390/molecules14103869
Received: 10 September 2009 / Revised: 28 September 2009 / Accepted: 28 September 2009 / Published: 29 September 2009
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p. 633-654
by  and
Molecules 2009, 14(2), 633-654; doi:10.3390/molecules14020633
Received: 1 January 2009 / Revised: 21 January 2009 / Accepted: 5 February 2009 / Published: 6 February 2009
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p. 2758-2785
by ,  and
Molecules 2008, 13(11), 2758-2785; doi:10.3390/molecules13112758
Received: 4 September 2008 / Revised: 13 October 2008 / Accepted: 29 October 2008 / Published: 6 November 2008
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p. 1156-1178
by ,  and
Molecules 2008, 13(5), 1156-1178; doi:10.3390/molecules13051156
Received: 5 February 2008 / Revised: 14 May 2008 / Accepted: 14 May 2008 / Published: 14 May 2008
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p. 1035-1065
by , , , ,  and
Molecules 2008, 13(5), 1035-1065; doi:10.3390/molecules13051035
Received: 1 February 2008 / Revised: 1 April 2008 / Accepted: 30 April 2007 / Published: 1 May 2008
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p. 892-903
by  and
Molecules 2008, 13(4), 892-903; doi:10.3390/molecules13040892
Received: 1 February 2008 / Revised: 16 April 2008 / Accepted: 16 April 2007 / Published: 18 April 2008
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p. 841-854
by , , , , , ,  and
Molecules 2008, 13(4), 841-854; doi:10.3390/molecules13040841
Received: 12 March 2008 / Revised: 6 April 2008 / Accepted: 7 April 2007 / Published: 10 April 2008
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p. 616-677
by , , , , , , ,  and
Molecules 2008, 13(3), 616-677; doi:10.3390/molecules13030616
Received: 11 January 2008 / Revised: 12 March 2008 / Accepted: 12 March 2008 / Published: 19 March 2008
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p. 519-547
by ,  and
Molecules 2008, 13(3), 519-547; doi:10.3390/molecules13030519
Received: 14 December 2007 / Revised: 25 February 2008 / Accepted: 25 February 2008 / Published: 3 March 2008
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p. 391-404
by , , ,  and
Molecules 2008, 13(2), 391-404; doi:10.3390/molecules13020391
Received: 6 February 2008 / Revised: 15 February 2008 / Accepted: 15 February 2008 / Published: 18 February 2008
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p. 412-431
by
Molecules 2008, 13(2), 412-431; doi:10.3390/molecules13020412
Received: 14 December 2007 / Revised: 9 February 2008 / Accepted: 11 February 2008 / Published: 18 February 2008
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p. 348-359
by , ,  and
Molecules 2008, 13(2), 348-359; doi:10.3390/molecules13020348
Received: 29 January 2008 / Revised: 11 February 2008 / Accepted: 11 February 2008 / Published: 12 February 2008
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p. 360-378
by , ,  and
Molecules 2008, 13(2), 360-378; doi:10.3390/molecules13020360
Received: 29 January 2008 / Revised: 11 February 2008 / Accepted: 11 February 2008 / Published: 12 February 2008
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p. 230-254
by , , ,  and
Molecules 2008, 13(2), 230-254; doi:10.3390/molecules13020230
Received: 4 January 2008 / Revised: 31 January 2008 / Accepted: 1 February 2008 / Published: 1 February 2008
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p. 204-211
by ,  and
Molecules 2008, 13(2), 204-211; doi:10.3390/molecules13020204
Received: 19 January 2008 / Accepted: 30 January 2008 / Published: 31 January 2008
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p. 96-106
by , ,  and
Molecules 2008, 13(1), 96-106; doi:10.3390/molecules13010096
Received: 14 December 2007 / Revised: 16 January 2008 / Accepted: 16 January 2008 / Published: 18 January 2008
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p. 46-68
by ,  and
Molecules 2008, 13(1), 46-68; doi:10.3390/molecules13010046
Received: 4 December 2007 / Revised: 11 January 2008 / Accepted: 11 January 2008 / Published: 16 January 2008
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p. 31-40
by , , , , , , ,  and
Molecules 2008, 13(1), 31-40; doi:10.3390/molecules13010031
Received: 2 November 2007 / Revised: 29 December 2007 / Accepted: 29 December 2007 / Published: 11 January 2008
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p. 2579-2588
by ,  and
Molecules 2007, 12(12), 2579-2588; doi:10.3390/12122579
Received: 29 October 2007 / Revised: 26 November 2007 / Accepted: 10 December 2007 / Published: 12 December 2007
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p. 2559-2566
by , , , ,  and
Molecules 2007, 12(11), 2559-2566; doi:10.3390/12112559
Received: 17 November 2007 / Revised: 27 November 2007 / Accepted: 27 November 2007 / Published: 29 November 2007
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p. 2484-2506
by ,  and
Molecules 2007, 12(11), 2484-2506; doi:10.3390/12112484
Received: 6 October 2007 / Revised: 8 November 2007 / Accepted: 9 November 2007 / Published: 12 November 2007
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p. 2380-2395
by  and
Molecules 2007, 12(10), 2380-2395; doi:10.3390/12102380
Received: 28 September 2007 / Revised: 29 October 2007 / Accepted: 29 October 2007 / Published: 30 October 2007
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p. 2396-2412
by  and
Molecules 2007, 12(10), 2396-2412; doi:10.3390/12102396
Received: 28 September 2007 / Revised: 29 October 2007 / Accepted: 29 October 2007 / Published: 30 October 2007
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p. 373-388
by  and
Molecules 2007, 12(3), 373-388; doi:10.3390/12030373
Received: 10 February 2007 / Revised: 5 February 2007 / Accepted: 5 February 2007 / Published: 8 March 2007
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Last update: 29 January 2016

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