Topical Collection "Prodrugs"

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A topical collection in Molecules (ISSN 1420-3049). This collection belongs to the section "Medicinal Chemistry".

Editor

Collection Editor
Dr. Jean Jacques Vanden Eynde
Laboratory of Organic Chemistry (FS), University of Mons-UMONS, Place du parc, 23, 7000 Mons, Belgium
Website: http://www.umons.be
E-Mail: jean-jacques.vandeneynde@ex.umons.ac.be
Phone: + 32 65 352589
Interests: heterocycles; microwave-induced synthesis; medicinal chemistry; green chemistry

Topical Collection Information

Dear Colleagues,

Working in the field of medicinal chemistry is a daily challenge. One has to design novel structures, prepare substances, purify them (an often tedious task), and “finally”, the substances are screened. With luck, some promising candidates will emerge from one’s chemical libraries. Then one has to go back to the lab and try to improve the efficacy of one’s leads by introducing some subtle modifications in their skeleton. At that point, one may realizes that there is an excellent potential drug but, some of its physical or pharmacological properties will hinder its development. Hopefully, under such circumstances, one will be able to circumvent those problems by conceiving some prodrugs.

This Topical Collection focuses on all kinds of efforts made in order to discover, characterize, and study substances that can be metabolized into active species. Bioconjugation, drug delivery methodologies, and other fields of research closely related to the prodrug approach will also be considered with great interest and pleasure.

Dr. Jean Jacques Vanden Eynde
Collection Editor

Keywords

  • prodrugs
  • prodrug

Related Special Issue

Published Papers (39 papers)


2014  ( 2 papers )


2011  ( 5 papers )


2010  ( 4 papers )


2009  ( 6 papers )


2008  ( 16 papers )


2007  ( 6 papers )


2014
by , , , , , ,  and
Molecules 2014, 19(9), 13251-13266; doi:10.3390/molecules190913251
Received: 19 May 2014; in revised form: 17 July 2014 / Accepted: 7 August 2014 / Published: 28 August 2014
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by , , , ,  and
Molecules 2014, 19(8), 12559-12576; doi:10.3390/molecules190812559
Received: 24 June 2014; in revised form: 1 August 2014 / Accepted: 11 August 2014 / Published: 19 August 2014
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2011
by , , , , ,  and
Molecules 2011, 16(6), 4660-4671; doi:10.3390/molecules16064660
Received: 15 March 2011; in revised form: 27 May 2011 / Accepted: 31 May 2011 / Published: 3 June 2011
Show/Hide Abstract | Cited by 4 | PDF Full-text (175 KB)

by , , , , , ,  and
Molecules 2011, 16(5), 4140-4164; doi:10.3390/molecules16054140
Received: 3 February 2011; Accepted: 3 May 2011 / Published: 19 May 2011
Show/Hide Abstract | Cited by 11 | PDF Full-text (456 KB)
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by , , , ,  and
Molecules 2011, 16(3), 2658-2671; doi:10.3390/molecules16032658
Received: 18 January 2011; in revised form: 16 March 2011 / Accepted: 21 March 2011 / Published: 23 March 2011
Show/Hide Abstract | Cited by 3 | PDF Full-text (370 KB)
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by , ,  and
Molecules 2011, 16(2), 1888-1900; doi:10.3390/molecules16021888
Received: 11 January 2011; in revised form: 25 January 2011 / Accepted: 17 February 2011 / Published: 22 February 2011
Show/Hide Abstract | Cited by 9 | PDF Full-text (197 KB)
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by ,  and
Molecules 2011, 16(1), 552-566; doi:10.3390/molecules16010552
Received: 22 November 2010; in revised form: 30 December 2010 / Accepted: 13 January 2011 / Published: 14 January 2011
Show/Hide Abstract | Cited by 2 | PDF Full-text (533 KB)
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2010
by , , ,  and
Molecules 2011, 16(1), 175-189; doi:10.3390/molecules16010175
Received: 22 November 2010; in revised form: 24 December 2010 / Accepted: 28 December 2010 / Published: 29 December 2010
Show/Hide Abstract | Cited by 2 | PDF Full-text (147 KB)
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by , , , , , , , ,  and
Molecules 2010, 15(3), 1232-1241; doi:10.3390/molecules15031232
Received: 2 February 2010; in revised form: 2 March 2010 / Accepted: 3 March 2010 / Published: 3 March 2010
Show/Hide Abstract | Cited by 2 | PDF Full-text (318 KB)
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by , , ,  and
Molecules 2010, 15(3), 1242-1264; doi:10.3390/molecules15031242
Received: 8 February 2010; in revised form: 2 March 2010 / Accepted: 3 March 2010 / Published: 3 March 2010
Show/Hide Abstract | Cited by 21 | PDF Full-text (292 KB)

by ,  and
Molecules 2010, 15(2), 842-856; doi:10.3390/molecules15020842
Received: 11 January 2010; in revised form: 30 January 2010 / Accepted: 3 February 2010 / Published: 5 February 2010
Show/Hide Abstract | Cited by 4 | PDF Full-text (338 KB)

2009
by , ,  and
Molecules 2009, 14(12), 5247-5280; doi:10.3390/molecules14125247
Received: 9 October 2009; in revised form: 8 December 2009 / Accepted: 14 December 2009 / Published: 15 December 2009
Show/Hide Abstract | Cited by 2 | PDF Full-text (394 KB)

by , , , , , , ,  and
Molecules 2009, 14(12), 5017-5026; doi:10.3390/molecules14125017
Received: 30 September 2009; in revised form: 22 November 2009 / Accepted: 30 November 2009 / Published: 2 December 2009
Show/Hide Abstract | Cited by 1 | PDF Full-text (452 KB)
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by , , ,  and
Molecules 2009, 14(11), 4517-4545; doi:10.3390/molecules14114517
Received: 10 October 2009; in revised form: 3 November 2009 / Accepted: 5 November 2009 / Published: 10 November 2009
Show/Hide Abstract | Cited by 21 | PDF Full-text (390 KB)
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by ,  and
Molecules 2009, 14(10), 4231-4245; doi:10.3390/molecules14104231
Received: 18 September 2009; in revised form: 13 October 2009 / Accepted: 19 October 2009 / Published: 22 October 2009
Show/Hide Abstract | Cited by 5 | PDF Full-text (139 KB)

by
Molecules 2009, 14(10), 3869-3880; doi:10.3390/molecules14103869
Received: 10 September 2009; in revised form: 28 September 2009 / Accepted: 28 September 2009 / Published: 29 September 2009
Show/Hide Abstract | Cited by 7 | PDF Full-text (89 KB)

by  and
Molecules 2009, 14(2), 633-654; doi:10.3390/molecules14020633
Received: 1 January 2009; in revised form: 21 January 2009 / Accepted: 5 February 2009 / Published: 6 February 2009
Show/Hide Abstract | Cited by 4 | PDF Full-text (209 KB)

2008
by ,  and
Molecules 2008, 13(11), 2758-2785; doi:10.3390/molecules13112758
Received: 4 September 2008; in revised form: 13 October 2008 / Accepted: 29 October 2008 / Published: 6 November 2008
Show/Hide Abstract | Cited by 18 | PDF Full-text (215 KB)
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by ,  and
Molecules 2008, 13(5), 1156-1178; doi:10.3390/molecules13051156
Received: 5 February 2008; in revised form: 14 May 2008 / Accepted: 14 May 2008 / Published: 14 May 2008
Show/Hide Abstract | Cited by 2 | PDF Full-text (423 KB)

by , , , ,  and
Molecules 2008, 13(5), 1035-1065; doi:10.3390/molecules13051035
Received: 1 February 2008; in revised form: 1 April 2008 / Accepted: 30 April 2007 / Published: 1 May 2008
Show/Hide Abstract | Cited by 35 | PDF Full-text (225 KB)

by  and
Molecules 2008, 13(4), 892-903; doi:10.3390/molecules13040892
Received: 1 February 2008; in revised form: 16 April 2008 / Accepted: 16 April 2007 / Published: 18 April 2008
Show/Hide Abstract | Cited by 3 | PDF Full-text (103 KB)

by , , , , , ,  and
Molecules 2008, 13(4), 841-854; doi:10.3390/molecules13040841
Received: 12 March 2008; in revised form: 6 April 2008 / Accepted: 7 April 2007 / Published: 10 April 2008
Show/Hide Abstract | Cited by 1 | PDF Full-text (130 KB)

by , , , , , , ,  and
Molecules 2008, 13(3), 616-677; doi:10.3390/molecules13030616
Received: 11 January 2008; in revised form: 12 March 2008 / Accepted: 12 March 2008 / Published: 19 March 2008
Show/Hide Abstract | Cited by 16 | PDF Full-text (461 KB)

by ,  and
Molecules 2008, 13(3), 519-547; doi:10.3390/molecules13030519
Received: 14 December 2007; in revised form: 25 February 2008 / Accepted: 25 February 2008 / Published: 3 March 2008
Show/Hide Abstract | Cited by 13 | PDF Full-text (165 KB)

by , , ,  and
Molecules 2008, 13(2), 391-404; doi:10.3390/molecules13020391
Received: 6 February 2008; in revised form: 15 February 2008 / Accepted: 15 February 2008 / Published: 18 February 2008
Show/Hide Abstract | Cited by 3 | PDF Full-text (640 KB)

by
Molecules 2008, 13(2), 412-431; doi:10.3390/molecules13020412
Received: 14 December 2007; in revised form: 9 February 2008 / Accepted: 11 February 2008 / Published: 18 February 2008
Show/Hide Abstract | Cited by 47 | PDF Full-text (634 KB)

by , ,  and
Molecules 2008, 13(2), 348-359; doi:10.3390/molecules13020348
Received: 29 January 2008; in revised form: 11 February 2008 / Accepted: 11 February 2008 / Published: 12 February 2008
Show/Hide Abstract | Cited by 11 | PDF Full-text (103 KB)

by , ,  and
Molecules 2008, 13(2), 360-378; doi:10.3390/molecules13020360
Received: 29 January 2008; in revised form: 11 February 2008 / Accepted: 11 February 2008 / Published: 12 February 2008
Show/Hide Abstract | Cited by 8 | PDF Full-text (114 KB)

by , , ,  and
Molecules 2008, 13(2), 230-254; doi:10.3390/molecules13020230
Received: 4 January 2008; in revised form: 31 January 2008 / Accepted: 1 February 2008 / Published: 1 February 2008
Show/Hide Abstract | Cited by 11 | PDF Full-text (155 KB)

by ,  and
Molecules 2008, 13(2), 204-211; doi:10.3390/molecules13020204
Received: 19 January 2008; Accepted: 30 January 2008 / Published: 31 January 2008
Show/Hide Abstract | Cited by 7 | PDF Full-text (147 KB)

by , ,  and
Molecules 2008, 13(1), 96-106; doi:10.3390/molecules13010096
Received: 14 December 2007; in revised form: 16 January 2008 / Accepted: 16 January 2008 / Published: 18 January 2008
Show/Hide Abstract | Cited by 14 | PDF Full-text (101 KB)

by ,  and
Molecules 2008, 13(1), 46-68; doi:10.3390/molecules13010046
Received: 4 December 2007; in revised form: 11 January 2008 / Accepted: 11 January 2008 / Published: 16 January 2008
Show/Hide Abstract | Cited by 19 | PDF Full-text (183 KB)

by , , , , , , ,  and
Molecules 2008, 13(1), 31-40; doi:10.3390/molecules13010031
Received: 2 November 2007; in revised form: 29 December 2007 / Accepted: 29 December 2007 / Published: 11 January 2008
Show/Hide Abstract | Cited by 10 | PDF Full-text (221 KB)

2007
by ,  and
Molecules 2007, 12(12), 2579-2588; doi:10.3390/12122579
Received: 29 October 2007; in revised form: 26 November 2007 / Accepted: 10 December 2007 / Published: 12 December 2007
Show/Hide Abstract | Cited by 2 | PDF Full-text (89 KB)

by , , , ,  and
Molecules 2007, 12(11), 2559-2566; doi:10.3390/12112559
Received: 17 November 2007; in revised form: 27 November 2007 / Accepted: 27 November 2007 / Published: 29 November 2007
Show/Hide Abstract | Cited by 4 | PDF Full-text (117 KB)

by ,  and
Molecules 2007, 12(11), 2484-2506; doi:10.3390/12112484
Received: 6 October 2007; in revised form: 8 November 2007 / Accepted: 9 November 2007 / Published: 12 November 2007
Show/Hide Abstract | Cited by 20 | PDF Full-text (167 KB)

by  and
Molecules 2007, 12(10), 2380-2395; doi:10.3390/12102380
Received: 28 September 2007; in revised form: 29 October 2007 / Accepted: 29 October 2007 / Published: 30 October 2007
Show/Hide Abstract | Cited by 4 | PDF Full-text (118 KB)

by  and
Molecules 2007, 12(10), 2396-2412; doi:10.3390/12102396
Received: 28 September 2007; in revised form: 29 October 2007 / Accepted: 29 October 2007 / Published: 30 October 2007
Show/Hide Abstract | Cited by 10 | PDF Full-text (167 KB)

by  and
Molecules 2007, 12(3), 373-388; doi:10.3390/12030373
Received: 10 February 2007; in revised form: 5 February 2007 / Accepted: 5 February 2007 / Published: 8 March 2007
Show/Hide Abstract | Cited by 2 | PDF Full-text (79 KB)

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.


Last update: 8 August 2014

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