Frontier in Biocatalysis and Biotransformations

Dear Colleagues,

In recent years, many new biocatalysts have been described and studied mostly from a biocatalytic perspective. Since more and more (meta)genome data become available, even more of those studies will appear and add to our knowledge on novel reactions and enzymes. However, the transfer to application needs more attention and, thus, scale-up. Enzyme production and optimization in combination with product isolation also need more attention. Thus, this Topic aims to focus on this chain, including the identification of novel enzymes from bioprospecting activities, producing enzymes and increasing yields from various host organisms, engineering biocatalysts by means of site-directed mutagenesis or directed evolution, putting enzymes together—even with chemical synthesis—yielding novel chemoenzymatic cascades, product isolation after processing or in situ, and even combinatorial approaches towards new products. All this needs research in the field of biocatalysis and biotransformation to bring us to new frontiers.

Asst. Prof. Dr. Dirk Tischler
Topic Editor