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Porphyrinoids Photosensitizers for Biomedical Applications

Topic Information

Dear Colleagues,

The rapid spread of problems associated with drug resistance towards the present usage of chemotherapeutics necessitates the research and development of new natural and synthetic photosensitive compounds (photosensitizers) for biomedical applications. Well-known porphyrinoids such as porphyrins, phthalocyanines, and their related derivatives are of interest for the development of more effective original photosensitive molecules. Attempts to combine the best of their properties aim to facilitate optical diagnosis by fluorescence and local treatment owning to photosensitization. The curative method known as photodynamic therapy (PDT) has photodynamic action and has received research interest for more than a century. The scope of the present Topic is to collect the best of the recent developments made in the use of porphyrinoid photosensitizers in synthetic schemes, chemical and optical characterization, and the evaluation of photobiological properties as new-generation photosensitizers. We seek to collect novel studies conducted in the area of photochemistry science, as well as in photobiology research investigations, evaluations of their efficacy in PDT and fluorescent diagnosis, and in their application as theranostics agents. Original papers from prominent colleagues working in multidisciplinary areas of chemistry, biology, and biophysics will be highly appreciated.

Dr. Ivan Angelov
Dr. Vanya N. Mantareva
Dr. Vesselin Kussovski
Topic Editors

Keywords

  • photosensitizers
  • porphyrins
  • phthalocyanines
  • mechanisms of photosensitization
  • photophysics
  • photochemistry
  • photobiology
  • optical diagnosis
  • photodynamic therapy
  • theranostics

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Published Papers