Topic Editors

Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, 5300-253 Braganca, Portugal
Centro de Química, Universidade do Minho (CQ/UM), Campus de Gualtar, 4710-057 Braga, Portugal

Progress in Drug Design: Science and Practice

Abstract submission deadline
28 February 2026
Manuscript submission deadline
30 April 2026
Viewed by
129

Topic Information

Dear Colleagues,

Drug design is a complex and evolving field within pharmaceutical science that aims to develop new synthetic compounds based on knowledge of biological targets. Over time, drug design has evolved into a well-organized science with a solid theoretical background and practical applications. Rational drug design uses knowledge of biological targets to create complementary molecules, involves ligand-based and structure-based design methods, and often employs computer-aided techniques for modeling and prediction.

The optimization of drug synthesis and properties including efficacy, safety, bioavailability, and metabolic stability should be considered; focus should be placed on "drug-like" properties to improve oral bioavailability and reduce toxicity. An increased emphasis should be placed on personalized medicine and targeted therapies, as well as the development of more sophisticated predictive models for drug efficacy and safety.

Drug design remains a critical component of pharmaceutical research, combining scientific innovation with practical applications to address unmet medical needs and improve patient outcomes.

Dr. Rui M. V. Abreu
Dr. Maria João Queiroz
Topic Editors

Keywords

  • rational drug design
  • computer-aided drug design
  • drug discovery
  • synthesis
  • biological targets
  • molecular docking
  • molecular dynamics
  • virtual screening
  • QSAR (quantitative structure–activity relationship)
  • pharmacokinetics

Participating Journals

Journal Name Impact Factor CiteScore Launched Year First Decision (median) APC
Biomolecules
biomolecules
4.8 9.4 2011 18.4 Days CHF 2700 Submit
Chemistry
chemistry
2.4 3.2 2019 17.2 Days CHF 1800 Submit
International Journal of Molecular Sciences
ijms
4.9 8.1 2000 16.8 Days CHF 2900 Submit
Molecules
molecules
4.2 7.4 1996 15.1 Days CHF 2700 Submit
Pharmaceuticals
pharmaceuticals
4.3 6.1 2004 13.9 Days CHF 2900 Submit

Preprints.org is a multidisciplinary platform offering a preprint service designed to facilitate the early sharing of your research. It supports and empowers your research journey from the very beginning.

MDPI Topics is collaborating with Preprints.org and has established a direct connection between MDPI journals and the platform. Authors are encouraged to take advantage of this opportunity by posting their preprints at Preprints.org prior to publication:

  1. Share your research immediately: disseminate your ideas prior to publication and establish priority for your work.
  2. Safeguard your intellectual contribution: Protect your ideas with a time-stamped preprint that serves as proof of your research timeline.
  3. Boost visibility and impact: Increase the reach and influence of your research by making it accessible to a global audience.
  4. Gain early feedback: Receive valuable input and insights from peers before submitting to a journal.
  5. Ensure broad indexing: Web of Science (Preprint Citation Index), Google Scholar, Crossref, SHARE, PrePubMed, Scilit and Europe PMC.

Published Papers

This Topic is now open for submission.
Back to TopTop