Therapeutic Potential of Natural Proteins and Peptides: Antimicrobial, Anticancer and Cytoprotective Activities
Topic Information
Dear Colleagues,
There is a large amount of research regarding natural proteins and peptides with antimicrobial, anticancer and cytoprotective activities, which can protect cells within various organs, such as the brain, heart, stomach, lymphatic organs, skin, liver, kidneys, bones and muscles, from various forms of injury and dysfunction. They are produced by a diversity of organisms encompassing microorganisms, plants and animals. The structures, mechanisms of action and other aspects of these proteins and peptides with therapeutic potential have been elucidated; for instance, they are potentially valuable in view of the rising resistance of pathogens to currently available medications, since they may offer novel mechanisms to combat diseases and potentially replace existing drugs, or mitigate side effects of existing drugs and/or synergize with them when used in combination.
This topic aims to collect original research and review articles detailing the extraction, isolation, chemical characterization, biological characterization, mechanistic elucidation, applications and other aspects of the aforementioned proteins and peptides. The submission of studies on their receptors is also welcome.
Prof. Dr. Tzi Bun NG
Dr. Jack Ho Wong
Topic Editors
Keywords
- antimicrobial, anticancer and cytoprotective
- microorganisms, plants and animals
- in vitro and in vivo models
- structure–activity relationship
- extraction, isolation and characterization methods
- structural elucidation
- mechanism of action
- practical applications