Magnetobiology and Magnetomedicine

Topic Information

Dear Colleagues,

The biological and medical effects of magnetic fields have attracted the attention of scientists for more than a hundred years. However, despite the widespread use of magnetic fields in medicine and biotechnology, the mechanisms of the interaction of a magnetic field with living systems are still poorly understood and largely mysterious. One of the reasons for this is the inherent complexity of biological systems, the study of which requires the consolidation and complementarity of the efforts of researchers representing different disciplines: biology, physics, medicine, chemistry, mathematics, biotechnology, nanomaterials, engineering, and programming. Thus, multidisciplinary research will focus both on discovering new biological effects and biomedical applications of magnetic fields, and on revealing the biophysical and biochemical mechanisms of already discovered phenomena. Studies that are related but not limited to the following aspects are welcome, including the effects and mechanisms of magnetic field interaction with biomolecules, cells, and organisms; effects and mechanisms of how organisms perceive, respond, and utilize magnetic fields; magnetic technologies that can be used in biological research or medicine, such as magnetic control of cell functions, magnetofection, new magnetic biomaterials, MRI (magnetic resonance imaging) and TMS (transcranial magnetic stimulations), magnetic surgery, magnetotherapy, and beyond.

Dr. Xin Zhang
Dr. Vitalii Zablotskii
Topic Editors

Keywords

Participating Journals

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Antioxidants antioxidants	6.6	12.4	2012	17.4 Days	CHF 2900
Cells cells	5.2	10.5	2012	16 Days	CHF 2700
International Journal of Molecular Sciences ijms	4.9	9.0	2000	20.5 Days	CHF 2900
Journal of Molecular Pathology jmp	1.1	2.3	2020	28.2 Days	CHF 1000
Magnetism magnetism	-	2.0	2021	37.5 Days	CHF 1000
Microorganisms microorganisms	4.2	7.7	2013	15.2 Days	CHF 2700
Symmetry symmetry	2.2	5.3	2009	17.1 Days	CHF 2400

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All Antioxidants Cells IJMS JMP Magnetism Microorganisms Symmetry

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Open AccessArticle

Life on Magnet: Long-Term Exposure of Moderate Static Magnetic Fields on the Lifespan and Healthspan of Mice

by Yixiang Fan, Xin Yu, Biao Yu, Xinmiao Ji, Xiaofei Tian, Chao Song and Xin Zhang

Antioxidants 2023, 12(1), 108; https://doi.org/10.3390/antiox12010108 - 31 Dec 2022

Cited by 9 | Viewed by 3335

Abstract

All living organisms on the Earth live and evolve in the presence of the weak geomagnetic field, a quasi-uniform static magnetic field (SMF). In the meantime, although the effects of moderate and high SMFs have been investigated on multiple aspects of a living [...] Read more.

All living organisms on the Earth live and evolve in the presence of the weak geomagnetic field, a quasi-uniform static magnetic field (SMF). In the meantime, although the effects of moderate and high SMFs have been investigated on multiple aspects of a living organism, a long-term SMF exposure of more than 1 year has never been reported. Here, we investigated the influence of a moderate SMF (70–220 mT head-to-toe) long-term continuous exposure (1.7 years) to two different SMF directions on healthy male C57BL/6 mice. We found that not only was the lifespan of the mice prolonged, but their healthspan was also improved. The elevated plus maze test and open field test show that SMFs could significantly improve the exploratory and locomotive activities of the aged mice. The Morris water maze test shows that SMFs could improve their spatial learning ability and spatial memory. Tissue examinations reveal that SMFs have an ameliorative effect on oxidative stress in the brain of aged mice, which was reinforced by the cellular assays, showing that SMFs could protect the PC12 cells from D-gal-induced senescence by increasing superoxide dismutase, catalase, and reducing the malonaldehyde levels. Therefore, our data show that the 1.7-year SMF exposure can improve both the lifespan and healthspan of naturally aged mice due to reduced oxidative stress, which indicates that SMFs have the potential to be used as an adjuvant physical therapy to reduce the ageing-induced health risks to benefit animals, and even humans. Full article

(This article belongs to the Topic Magnetobiology and Magnetomedicine)

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Open AccessArticle

Static Magnetic Fields Protect against Cisplatin-Induced Kidney Toxicity

by Xin Yu, Xinmiao Ji, Yixiang Fan, Biao Yu, Xinyu Wang, Chuanlin Feng, Lei Zhang, Chao Song and Xin Zhang

Antioxidants 2023, 12(1), 73; https://doi.org/10.3390/antiox12010073 - 29 Dec 2022

Cited by 8 | Viewed by 2698

Abstract

Cisplatin is one of the most widely used anti-cancer drugs that can effectively inhibit the growth of multiple types of cancer. However, its clinical application is limited by its severe side effects, especially kidney toxicity, caused by cisplatin-induced oxidative stress, inflammation and kidney [...] Read more.

Cisplatin is one of the most widely used anti-cancer drugs that can effectively inhibit the growth of multiple types of cancer. However, its clinical application is limited by its severe side effects, especially kidney toxicity, caused by cisplatin-induced oxidative stress, inflammation and kidney cell apoptosis. Here, we found that moderate (a few hundred mT) quasi-uniform static magnetic fields (SMFs) could inhibit cisplatin-induced renal proximal tubular cell death, especially the vertically downward direction SMF. RNA-seq experiments demonstrate that SMFs induced differential gene expressions that are closely associated with oxidative stress, apoptosis, cytokine production, transmembrane transport and DNA repair. In vivo experiments show that SMFs can reduce cisplatin-induced kidney injury in cisplatin-administrated tumor-bearing mice by reducing oxidative stress, inflammation and cell apoptosis. Furthermore, high-dose cisplatin-induced acute nephrotoxicity can be effectively alleviated by SMF treatment of as little as one day, which significantly reduced the reactive oxygen species levels in kidneys and prolonged the mice’s survival. Moreover, the concentration of cisplatin in the kidney was significantly attenuated in SMF-treated mice. Therefore, our study demonstrates the effects of moderate SMFs as a novel physical method to reduce oxidative stress, and revealed their future potential to be used against cisplatin-induced kidney toxicity in cancer treatment. Full article

(This article belongs to the Topic Magnetobiology and Magnetomedicine)

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