Role of Proteomics in Drug Development and Delivery

Dear Colleagues,

In recent years, proteomics has become a cutting-edge tool in biomedical research due to its high throughput and depth of protein coverage. Proteomics provides a comprehensive analysis of protein expression and post-translational modifications in specific tissues, cells, and cellular subfractions, enabling the identification and characterization of disease-specific proteins for drug development. Additionally, proteomics is used to study the mechanisms of drug action, evaluate drug efficacy, and identify potential adverse drug effects. Proteomics also plays a critical role in drug delivery by characterizing and optimizing cell or cell-derived drug carriers, such as stem cells and extracellular vesicles (EVs), as well as evaluating the safety and efficacy of various drug delivery strategies.

This Special Issue will accept manuscripts that report on the critical roles of proteomics in drug development and delivery, including, but not limited to, the following themes:

• Identifying and validating the druggable proteome and critical drug targets;
• Studying the mechanism of drug action;
• Evaluating drug efficacy and identifying adverse drug effects;
• Characterizing complex components of drugs or drug delivery systems, such as extracellular vesicles (EVs), stem cells, or the therapeutic secreted proteome from stem cells;
• Developing cutting-edge proteomics technologies for application in drug development and delivery.

Dr. Hao Yang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.