Search Results (513)

Quercus suber bark, known as cork, is an important fire-adaptive trait of this Mediterranean species. However, the increased frequency of wildfires and poor forest management practices can be significant challenges in managing the sustainable exploitation of cork oak stands. This study evaluates cork’s thermal behavior and organoleptic quality for commercial applications under three experimental fire scenarios: prescribed burn, low-intensity wildfire, and high-intensity wildfire. Bench-scale tests were conducted using a vertical mass loss calorimeter to simulate heat exposure levels, measuring temperature changes at four cork depths and quantifying heat-induced damage. Morphological traits—cork thickness, corkback thickness, and relative humidity—were recorded as predictor variables. Additionally, organoleptic and aromatic analyses were performed to assess the suitability of fire-exposed cork for wine stopper production. Results were consistent with the available literature, confirming that cork thickness significantly reduces the maximum temperature at the phellogen level. Specifically, mean cork thickness showed a significant negative effect on Tmax4 (β = −0.02, p < 0.001), indicating a consistent decrease in internal temperatures with increasing thickness across all heat flux levels. By contrast, cork consumption (mass loss) was primarily driven by heat flux intensity rather than cork structural traits. Aromatic profiling and organoleptic analysis revealed the presence of smoke-related compounds in cork samples exhibiting external carbonization. This effect was observed under higher heat flux exposure (particularly at 25 and 50 kW m⁻²), where visible charring occurred. Under these conditions, commercial quality may be partially compromised, whereas samples without external carbonization did not show comparable aromatic alteration. Further field validation is recommended. Full article

Background: The COVID-19 pandemic significantly altered the daily routines of young adults. This study investigated alcohol consumption patterns and associated factors among young adults in Romania during this period. Method: A cross-sectional study was conducted using an online survey. Participants were asked to retrospectively report their alcohol consumption patterns before and during the COVID-19 pandemic, including the period of university campus closures. A cohort of 249 young adults (68.6% female) participated in an online survey focused on their alcohol consumption patterns, utilizing the standardized AUDIT-C questionnaire and some modified questions to better establish the habit of drinking. Results: In total, 41.7% of the included subjects were in medical school, 10% in IT, and 44% in various areas of work. Most respondents were female, between 20 and 25 years old (65%) and living in urban areas, with wine being the most favorable drink. Regarding AUDIT scores, approximately 90% fall into low-risk drinking or even abstinence, 10% belong to the high-risk group of alcohol consumption, and 3 people have a high score, which suggests drinking abuse and the likelihood of developing alcohol dependence. A comparison of pre- to post-closure drinking among medical students showed statistically significant changes in the typical number of drinks per week (from 11.5 to 9.9) and maximum drinks per day (from 4.9 to 3.3) and a slight increase in typical drinking days per week (from 3 to 3.2), p < 0.05, outlining a decrease in alcohol consumption. Conclusions: The study highlights specific drinking patterns during the pandemic. While some individuals decreased consumption, a significant portion remained at risk for alcohol-related complications, emphasizing the need for targeted screening and prevention programs. Full article

The effect of alcohol on health is a controversial topic when it comes to the moderate or conscious consumption of fermented beverages. The recent claim by the World Health Organisation (WHO) and the European Heart Network (EHN) that the safe level of alcohol consumption is zero has compromised the efforts of the fermentation scientific community in developing healthier and more sustainable beverages. Therefore, the objective of this review was to assess the scientific background for such a claim that appears to be the result of recent scientific evidence. Using the meta-analytic data supporting WHO and EHN guidelines, it was possible to demonstrate that fermented beverages (e.g., wine and beer) have lower effects compared to spirits, that some population ethnicities have higher sensitivity to alcohol, and that drinking patterns influence the outcomes. Moreover, higher relative risks associated with younger individuals are mostly related to injuries (e.g., car accidents, self-inflicted injuries) and not with diseases. Sequential WHO studies produced significantly higher limits and emphasized that preventive policies should be tailored to populations at higher risk. In conclusion, the statement that “all alcohol is hazardous” has no scientific background and should be understood under the perspective that “one drink is too many and one thousand is never enough” used in alcoholism prevention. Fermentation researchers should continue their efforts on the promotion of healthier lifestyles, sustainable development and on the preservation of cultural heritage under the responsible drinking perspective. Full article

The use of oenological additives is an emerging trend in winemaking aimed at improving technological properties. Recent studies suggest that these additives may also influence aroma persistence after wine consumption by modulating the retention of aroma compounds in the oral cavity. The aim of this study was to evaluate the effect of three commercial oenological additives, hydrolysable tannins (gallotannin and ellagitannin) and yeast mannoproteins, on the oral aroma retention of selected aroma compounds in red and white wines. Eight aromatised wines were prepared, including three red and three white wines with additives and two control wines without additives. Thirty-eight volunteers rinsed with each wine following the Spit-Off Odorant Measurement (SOOM) procedure. Oral aroma retention was calculated by comparing aroma levels in expectorated samples with those in wines prior to oral processing. Results showed that additive type significantly affected oral aroma retention (p < 0.05), depending on both the aroma compound and the wine matrix. In red wines, tannins increased the oral retention of most aroma compounds (5–20%), whereas in white wines, tannins reduced aroma retention. Mannoproteins enhanced oral aroma retention (5–40%) in both wine types. These results highlight the role of interactions between oenological additives, aroma compounds, and the wine matrix in modulating oral aroma retention. Full article

In the big-data-driven artificial intelligence era, similarity search, as a core operation in machine learning and data mining, demands high speed, energy efficiency, and scenario adaptability. Conventional electronic content-addressable memory (ECAMs) suffer from inherent RC delay bottlenecks, whereas existing optical content-addressable memory (OCAMs) are restricted by fixed bit-widths and limited distance metrics. In this work, we propose a variable bit-width all-optical CAM leveraging multi-segment modulators and phase-change material (PCM) Sb₂Se₃. The multi-segment memory unit (MSMU) therein compresses N-bit binary data into a single analog photonic unit, supporting direct data writing/loading without digital-to-analog converters (DACs) and flexible trade-offs between precision, storage capacity, noise immunity, and energy while enabling Hamming and nonlinear distance metrics. A six-element three-bit OCAM prototype was fabricated on a silicon nitride silicon-on-insulator (SiN-SOI) platform. Despite the absence of integrated high-speed phase shifters, the device still achieves reliable optical data storage and retrieval. K-nearest neighbor (kNN) simulations based on experimentally derived statistical data—validated on the iris, wine, and breast cancer datasets—show that the three-bit operating mode achieves classification accuracy comparable to Manhattan/Euclidean distances at high signal-to-noise ratios (SNRs), while the one-bit mode exhibits strong noise robustness. Energy consumption is 364 fJ/bit (3-bit) and 890 fJ/bit (1-bit). This work provides a high-speed, energy-efficient, and reconfigurable all-optical similarity search solution with experimentally verified device performance and dataset-validated applicability, showing great potential for widespread deployment in data-intensive machine learning and data-mining applications. Full article

This study evaluates the impact of eight commercial oenological tannins—sourced from grape seed, grape skin, cherry, quebracho, acacia, tara, chestnut, and oak—on the phenolic composition and color evolution of a rosé wine during oxidative storage. The tannins were initially characterized for their phenolic richness, antioxidant capacity, oxygen consumption rate, and iron chelating ability. Their effects were then assessed in a lab-scale rosé wine produced without sulfur dioxide, where each tannin was added individually. Results revealed that condensed tannins, particularly from grape skins, significantly enhanced the initial color intensity, while hydrolyzable tannins such as chestnut and oak better preserved color stability over time. Chestnut tannin showed the highest antioxidant and oxygen consumption activities, correlating with its greater performance in limiting oxidative degradation. Although some tannins contributed to anthocyanin loss, evidence suggests a role in promoting pigment polymerization and color stabilization. Full article

Thailand’s 2024 excise tax reform aimed to stimulate the tourism economy through the elimination of import tariffs and the reduction in excise rates on wine. This study evaluates the causal economic and distributional impacts of this policy intervention. The analysis employs a quasi-experimental Doubly Robust Difference-in-Differences (DR-DiD) estimator on a stratified cluster sample to isolate shifts in consumption expenditure, volume, and net ethanol intake. Results indicate a null effect for the general population, which confirms that the price floor remained prohibitive for median earners despite the tax reduction. The top income quintile conversely exhibited a statistically significant “additive premiumization” effect characterized by a surge in wine quantity without the substitution of other beverage categories. This behavioral shift generated a substantial Net Economic Loss driven by the divergence between foregone tax revenue and projected human capital productivity losses. The policy consequently functioned as a regressive fiscal transfer to the elite and created severe allocative inefficiency. These findings suggest that ad valorem tax incentives for luxury goods in emerging markets generate deadweight loss. Future policy strategies should therefore prioritize specific volumetric taxation to align fiscal incentives with public health objectives. Full article

Alcohol is widely consumed across cultures and is often used to facilitate relaxation or sleep initiation. This narrative review critically examines evidence published over the past decade (2015–2025) on the effects of alcohol, including wine, on sleep health in community-dwelling adults. Priority was given to systematic reviews and meta-analyses, followed by high-quality observational and experimental studies. Across study designs, evidence consistently shows that although alcohol may reduce sleep onset latency, it disrupts sleep architecture, suppresses rapid eye movement sleep, increases sleep fragmentation, and impairs breathing during sleep, particularly in the second half of the night. Habitual alcohol consumption is associated with poorer subjective sleep quality, insomnia symptoms, and increased risk of sleep-disordered breathing. Mechanistic pathways include effects on neurotransmission, sleep homeostasis, circadian regulation, thermoregulation, and alcohol metabolism during sleep. Evidence also suggests that the timing of alcohol intake and alignment with circadian rhythms may modify these effects, with earlier consumption potentially reducing some adverse outcomes. A brief section addresses the reciprocal relationship, showing that circadian disruption, shift work, and evening chronotype are associated with higher alcohol use. Although wine contains bioactive compounds such as melatonin and polyphenols, current evidence indicates that these components are present at levels insufficient to provide meaningful sleep benefits. Overall, alcohol, including wine, should not be considered a sleep aid, and public health messaging should emphasize dose, timing, and regularity of alcohol consumption in relation to sleep health. Full article

The growing interest in precision agriculture has led, in recent years, to an increase in the adoption of Internet of Things (IoT) technologies in the service of smart agriculture to optimize agricultural production processes through the monitoring of environmental conditions and prevent food loss. This work stems from research conducted as part of the Tech4You project, where the enabling digital technologies developed in Spoke 6 contribute to the advanced solutions envisaged by Spoke 3 to facilitate the transition to a sustainable agrifood system. In particular, we present the design and evaluation of a multi-hop Device-to-Device (D2D) communication architecture that leverages Long Range (LoRa) technology, specifically designed for monitoring vineyards in the context of passito wine production. The proposed framework addresses the challenge of monitoring mobile containers for grapes during the drying phase, a critical stage in which inadequate temperatures and humidity can promote the growth of fungi and the formation of mycotoxins. The integration of simulation-based performance evaluation with a multi-layer system architecture is presented in this work. The objective is to compare the performance of different routing strategies in choosing data forwarding paths to the gateway. The simulation results show that the proposed routing strategy, which is based on learning but also focuses on energy consumption, offers good performance. In particular, it achieves packet delivery rates of over $92\%$ and preserves over $95\%$ of active nodes after 2 h of operation. Energy-aware routing strategies also perform well compared to those that only consider the distance from the destination, but overall, the proposed strategy achieves a better trade-off on the metrics analyzed. Full article

The overall health impact of alcohol remains controversial. The Global Burden of Disease (GBD) study made headlines in 2018 by stating that zero alcohol was the safest option. However, its 2022 update introduced age-specific adaptations, asserting that moderate drinking may offer net benefits in some populations. The 2025 U.S. Surgeon General report also discouraged any alcohol intake because of associated cancer risks, but a simultaneous report by the National Academies emphasized tailoring recommendations to individual risks. Mendelian randomization (MR) studies found no health benefits and highlighted increased risks—even at low alcohol doses—challenging dozens of conventional epidemiologic findings in large observational cohorts, some of them of high methodological quality. Given these contradictions, there is a pressing need for large randomized controlled trials in drinkers promoting cessation versus moderation. While small trials have shown some metabolic and cardiovascular benefits of moderate red wine consumption, no large-scale randomized trial has yet assessed hard clinical outcomes comprehensively. Without such evidence, debates will persist. Current guidelines appropriately discourage alcohol in certain populations, but generalizations such as “no safe level of alcohol” might lack sufficient empirical support and perhaps they need a tailored and practical strategy in the context of precision medicine. A balanced, evidence-based approach—free from bias, independent of the industry and grounded in rigorous research—is essential for informed public health policy decisions. Full article

Background: Little is known about the relation between total alcohol intake and beverage types with the risk of heart failure (HF) and its subtypes in the veteran population. This study aims to examine the associations between total and type of alcohol consumption and risk of HF and its subtypes, namely HF with reduced [HFrEF] and preserved [HFpEF] ejection fraction, in a large cohort of US veterans. Methods: The study cohort included 401,348 Million Veteran Program participants with complete alcohol information collected through a survey and no HF at baseline. HF events were defined as 1 inpatient or 1 outpatient diagnosis code together with at least two ejection fraction (EF) measurements. We defined HFrEF as HF with left ventricular ejection fraction (LVEF) of ≤40% and HFpEF as heart failure with LVEF ≥ 50%. The associations between alcohol intake, type of beverage consumed (i.e., beer, wine, or liquor), and incidence of HF, HFpEF, and HFrEF were assessed using Cox proportional hazard models. Restricted cubic spline regression was used to assess for a dose–response association between alcohol consumption and the risk of HF. Results: Mean age was 65 years, and 91% were men. With a mean follow-up of 6.4 years, we observed 38,420 incident HF events (15,356 HFrEF, 19,047 HFpEF, and 4017 HF with an EF value of 41–49%). Compared to never drinkers, multivariable adjusted hazard ratios for HF were 0.90 (95% CI: 0.86, 0.94), 0.88 (95% CI: 0.84, 0.93), 0.86 (95% CI: 0.81, 0.91), 0.92 (95% CI: 0.86, 0.98), 0.95 (95% CI: 0.84, 1.06), and 1.08 (95% CI: 1.01, 1.15) for current drinkers of 0.1–0.5, 0.6–1, 1.1–2, 2.1–3, 3.1–4 drinks/day, and heavy drinkers (i.e., >4 drinks/day and/or those diagnosed with alcohol use disorder), respectively. We found a similar association between alcohol intake and risk of HFpEF and HFrEF, except heavy drinking was significantly associated with HFrEF (HR: 1.13, 95% CI: 1.02, 1.24), not HFpEF (HR: 1.05, 95% CI: 0.96, 1.13). Types of alcoholic beverage preference did not influence the alcohol-HF relation. Conclusions: Our data are consistent with a J-shaped relation between alcohol consumption and risk of heart failure, irrespective of subtypes. Full article

Introduction: Alcohol consumption is a significant risk factor for hypertension (HTN), a prevalent condition that substantially affects cardiovascular health. In Peru, where various traditional alcoholic beverages exist, the relationship between alcohol consumption and HTN has not been fully explored. Objective: To determine the association between different patterns of alcohol consumption, types of beverages, and various types of HTN. Methods: This cross-sectional analytical study utilized data from the Peruvian Demographic and Family Health Survey (2018–2023), including 236,243 adults (55.95% male; mean age: 41.06 years). General HTN, isolated systolic hypertension (ISH), isolated diastolic hypertension (IDH), and systolic-diastolic hypertension (SDH) were evaluated. Alcohol consumption was assessed through self-reported questionnaires evaluating consumption pattern (non-excessive vs. excessive), intensity (light, moderate, heavy), consistency (intermittent vs. consistent), and primary beverage type, including both commercial and traditional Peruvian drinks. Results: Excessive alcohol consumption was significantly associated with an increased risk of HTN (aPR: 1.19, 95% CI: 1.07–1.31), IDH (aPR: 1.61, 95% CI: 1.20–2.16), and SDH (aPR: 1.45, 95% CI: 1.18–1.78). Excessive alcohol consumption was significantly associated with an increased risk of HTN (aPR: 1.19, 95% CI: 1.07–1.31), IDH (aPR: 1.61, 95% CI: 1.20–2.16), and SDH (aPR: 1.45, 95% CI: 1.18–1.78). Consumption of traditional beverages such as chicha and Masato was associated with an elevated risk of various types of HTN. In contrast, wine consumption demonstrated a protective association against general HTN and IDH. Conclusions: Alcohol consumption patterns and beverage types have differential effects on HTN risk in the Peruvian population. These findings underscore the need for culturally adapted prevention strategies and more nuanced public health recommendations regarding alcohol consumption in Peru. Full article

Circular economy (CE) strategies in the agri-food sector hold strong potential for reducing waste, enhancing resource efficiency, and promoting sustainable value creation. However, early-stage assessment of innovative valorisation pathways remains challenging due to limited data availability and heterogeneous sustainability trade-offs. This study presents a multi-criteria evaluation tool designed to identify sustainability hotspots and support the preliminary screening of CE solutions based on easily obtainable information. The tool combines a structured literature review with expert-based scoring across environmental (ENV), economic (EC), and social (SOC) dimensions. Its applicability was demonstrated through the following three case studies: (i) reconstitution of cheese approaching expiration, (ii) extraction of polyphenols from grape-wine residues via subcritical water extraction, and (iii) biodegradable mulching film production from grape-wine pomace. Results show that the tool successfully differentiates sustainability performance across value chain areas Residue, Final Product, and Process (RES, FP, and PRO) and reveals critical gaps requiring further investigation. Scenario 3 achieved the higher overall score (69.7%) due to fewer regulatory constraints, whereas Scenarios 1 and 2 (61.2% and 54.5%, respectively) are penalised due to the more regulations for human consumption. The proposed tool offers a practical and efficient method to support researchers and industry stakeholders in identifying CE strategies with the highest potential for sustainable development. Full article

Background: The relationship between alcohol consumption and vascular function remains controversial. This study aimed to examine the association between total alcohol intake, type of alcoholic beverage, and arterial stiffness across different vascular territories in young Spanish adults, with special attention to sex-specific patterns. Methods: A descriptive cross-sectional study was conducted. Using consecutive non-probability sampling, 501 participants (222 men and 279 women) aged 18–34 years, were recruited from the urban population of Salamanca. Alcohol consumption was assessed using a standardized questionnaire and quantified in grams per week overall and by different types of drinks (wine, beer or spirits drinks). Arterial stiffness was evaluated using pulse pressure (PP), carotid–femoral pulse wave velocity (cf-PWV), brachial–ankle pulse wave velocity (ba-PWV), cardio–ankle vascular index (CAVI), and central augmentation index corrected to a heart rate of 75 beats per minute (CAIx75). Results: The mean age of the sample was 26.58 ± 4.40 years, and was significantly higher in men than in women (27.04 ± 4.41 vs. 26.22 ± 4.37 years; p = 0.040). The mean values for vascular function parameters were as follows: PP 42.86 ± 8.45 mmHg, cf-PWV 5.60 ± 1.29 m/s, ba-PWV 38 10.80 ± 1.01 m/s, CAVI 6.13 ± 0.75, and CAIx75 7.71 ± 19.74. Participants reporting alcohol consumption showed lower ba-PWV values compared with abstainers, while no consistent associations were observed for central arterial stiffness parameters. In sex-stratified analyses, higher total alcohol intake (β = −0.002, 95% CI: −0.004–−0.001), as well as beer (β = −0.004, 95% CI: −0.007–−0.001), and spirit consumption (β = −0.004, 95% CI: −0.006–−0.001), were inversely associated with ba-PWV exclusively in men. In women, spirit consumption was positively associated with CAIx75 (β = 0.044, 95% CI: 0.006–0.081). The magnitude of the observed differences in ba-PWV was modest and occurred in a predominantly low-risk population. Conclusions: In young adults, alcohol consumption was associated with differences in peripheral arterial stiffness, primarily reflected by ba-PWV, with clear sex-specific patterns. These findings do not support a causal or protective effect of alcohol consumption and should be interpreted cautiously due to the cross-sectional design of the study. The results highlight the importance of considering sex and vascular territory when evaluating early markers of vascular aging in young populations. Clinical trial registration: [ClinicalTrials.gov], identifier [NCT05819840]. Full article

Reducing the alcohol content of wines has received increasing attention, and various strategies have been proposed for this aim. In this study, non-Saccharomyces yeasts isolated from Uruguayan vineyards were screened to identify strains with low ethanol production for use in mixed cultures. Twenty-six strains belonging to six species were evaluated, considering key oenological parameters such as ethanol and glycerol production, glucose and fructose consumption, and absence of organoleptic defects. Based on these criteria, three strains from two genera were selected: Starmerella bacillaris (Sb1 and Sb2) and Metschnikowia fructicola (Mf2). In pure cultures, Starmerella bacillaris showed high sugar consumption along with high glycerol production. Subsequently, co-inoculation and sequential inoculation conditions were tested by combining the selected strains with commercial Saccharomyces cerevisiae (Sc). With Mf2 + Sc sequential inoculation, high sugar consumption, increased glycerol production, and a significant reduction in ethanol were observed compared to the control. For Starmerella bacillaris, only Sb1 achieved consistent alcohol reductions in sequential strategies. With co-inoculation, both strains reduced ethanol by 0.2–1% v/v, although only Sb1 showed complete sugar depletion. Overall, the results demonstrate a marked dependence of fermentation behavior on the strain and highlight the importance of studying biocompatibility and inoculation strategy in mixed cultures. Full article