Search Results (77)

Koalas are an iconic Australian species now classified as nationally endangered due to habitat loss, predation, disease, and vehicle collisions. Yet, because of their nocturnal and arboreal nature, koala movement on the ground between trees remains poorly described. Ground visits are fraught with danger, with two-thirds of koala deaths occurring due to vehicle strikes and dog attacks. Quantifying these behaviours can provide insights for conservation efforts targeted to their time on the ground. To quantify detailed movement patterns, we collared nine koalas in a highly fragmented agricultural landscape with tri-axial accelerometers for 8.50 ± 1.17 days. Using an annotated dataset of observed behaviours, we trained Random Forest models to classify four main behavioural states: Motionless in Tree, Feeding & Grooming in Tree, Other Movement in Tree, and Walking. Koalas spent 57.5% ± 14.2% of their time moving in trees, 26.8% ± 13.5% motionless in trees, 15.6% ± 2.7% feeding and grooming, and only 0.2% ± 0.1% walking on the ground (around 3 min daily). Koalas walked most frequently between 2 am and 5 am. Our findings highlight a major discrepancy between mortality rates on the ground and frequency of ground time, indicating that focused mitigation during these infrequent events could yield disproportionately high conservation benefits. Full article

Assistance dogs provide many important benefits and improve the quality of life of the humans they serve. Puppy raisers provide the initial training of dogs that may become assistance dogs—training of basic commands such as sit, socializing and desensitizing the dog by exposing the dog to different people, novel environments and novel situations. When university students act as puppy raisers, they often bring their dog with them to class. Having an in-training assistance dog in the classroom might be disruptive to some students such as those who are allergic to dogs, anxious around dogs, or who object to dogs for religious reasons. Bringing an in-training assistance dog to class might also be disruptive to the puppy raiser if they need to direct their attention away from class to the dog to manage the dog’s behavior. The in-training assistance dog itself may experience stress from being in a novel environment with novel people. This study surveyed instructors, students, and puppy raisers in classes visited by in-training assistance dogs. In general, students reported having positive attitudes about having in-training assistance dogs in class; puppy raisers reported few problems and that their dogs experience few, if any, signs of stress. The results suggest that university students can continue to provide the initial training for dogs without negative consequences to the puppy raiser, instructor, or other students in the classes visited by the in-training assistance dogs. Full article

Animal-assisted interventions (AAIs) or Services (AAS) may cause stress in participating dogs, making the selection of suitable individuals essential to prevent strain. Different non-standardized approaches currently exist to assess dogs’ suitability for AAIs. This preliminary study aimed at evaluating two combined tools, a behavioural aptitude test (SuiTe) and an ad hoc revised questionnaire incorporating C-BARQ, for pre-screening dog suitability for AAIs, also in relation to salivary cortisol measured by enzyme immunoassay in N = 38 dogs. Dogs’ behavioural responses to environmental and social stimuli were scored on an X-Y scale and classified by two independent evaluators as suitable (S), pending suitability (P), or unsuitable (U). Non-parametric tests were performed (p < 0.05). Results indicated significant differences between dogs classified as S or P versus U, both in SuiTe valence scores (higher in S and P) and in separation, attachment, and fear/anxiety behaviours assessed by the questionnaire (higher in U). However, suitability in the SuiTe was lower than that assessed by caregivers through an open question. Our study highlights the complexity of this assessment and the limited awareness of caregivers regarding the situations their dogs face every day. Future analyses will refine this multiparametric approach within a One Welfare perspective, ensuring the welfare of both animals and humans involved in AAIs. Full article

Serum activity of paraoxonase-1 (PON-1) decreases in canine inflammation. This study aimed to evaluate how frequently PON-1 activity is reduced across different disease categories and to assess its potential prognostic significance. PON-1 activity was measured in 482 samples (435 first visit, 47 follow-up) collected during routine clinical activities. The emergency/first-opinion unit (EF) had the highest frequency of low values (18.3%) and lower median PON-1 activity (170.3 U/mL) compared with other units. The proportion of lower values and median PON-1 values were, respectively, significantly higher and lower in acute/severe diseases compared with chronic/mild diseases (13.3 vs. 7.1%; 177.0 vs. 192.9 U/mL) and in hospitalized compared with non-hospitalized dogs (27.7 vs. 4.5%; 150.0 vs. 193.0 U/mL). Low PON-1 activity may predict the need for hospitalization: values < 45.7 U/mL have a likelihood ratio of 14.4. The proportion of lower values and the median Paraoxonase-1 activity did not differ between survivors and non-survivors (18.2 vs. 25.0%; 162.0 vs. 161.3 U/mL). However, PON-1 activity diminished during hospitalization only in non-survivors. PON-1 activity should be measured in routine practice, especially in the EF; hospitalization may be warranted when results are markedly low. Decreases in PON-1 activity during hospitalization may suggest a negative outcome. Full article

Fear, anxiety, and stress (FAS) in canine patients is a growing concern for the veterinary industry. FAS affects the health of the patient while also increasing the risk to veterinary staff. Studies show that many veterinarians do not feel confident in managing behavioural issues like FAS, making engaging effectively with clients more difficult. Pre-visit pharmaceuticals (PVPs) can be an important tool in mitigating the effects of FAS; however, conclusive research is lacking on the efficacy of many of the medications and combinations currently used for this purpose. A comprehensive literature search was conducted in multiple databases. The most current research available on medications identified as widely used for treating FAS, and available for use in New Zealand, has been reviewed and discussed. Combinations selected for inclusion were the ‘chill protocol’ of acepromazine, gabapentin, and melatonin. Single agents included are clonidine, dexmedetomidine, gabapentin, and trazodone. Research into the use of the ‘chill protocol’ suggests this may be a combination particularly useful in highly stressed and aggressive dogs; however, additional studies need to be conducted to strengthen the evidence for its use. A multimodal approach has been identified as being desirable when addressing FAS in a clinical setting, with less evidence to support the use of single-agent medications in mitigating problematic behaviours. Full article

In recent years, pet owners have been making significant efforts to ensure the well-being of their animals. One straightforward approach to enhance their welfare involves greater attention to nutrition. Consequently, pet owners have become increasingly sensitive regarding the food they provide for their pets. The aim of this study is to examine this sensitivity by investigating the extent to which cat and dog owners prioritize quality attributes and ingredients when selecting pet food. For this purpose, a survey was conducted with pet owners (n = 519) who visited veterinary clinics, using a random sampling method. Of the participants, 51.25% were male and 48.75% were female, with the highest participation observed in the 18–34 age group (60.50%). Among the respondents, 64.93% owned cats, while 35.07% owned dogs. Additionally, 66.67% of pet owners reported using both wet and dry food. When selecting pet food, 42.58% of participants stated that they relied on recommendations from veterinarians. “Pet preference (palatability)” clearly emerged as the most important selection criterion, receiving the highest average score (3.90) and highlighting its decisive influence on purchasing decisions as owners appeared to prioritize what their pets liked most. In contrast, “visual appeal of the food” received the lowest score (2.47). A significant difference (p < 0.001) was found regarding whose recommendation influenced the purchase decision. Moreover, a negative correlation was identified between price sensitivity and other selection criteria, suggesting that price was not a primary driver in most participants’ decisions and became less important as quality-related factors gained priority. Overall, pet preference (palatability) stood out as the dominant driver of purchasing decisions. Full article

Rickettsia parkeri strain Atlantic rainforest is an emerging pathogen in Brazil, but human infections remain rarely reported. We report the first confirmed case in the municipality of Caraguatatuba on the northern coast of São Paulo State, Brazil. A 37-year-old man was bitten by an Amblyomma ovale tick while visiting a forested area. Six days later, he developed a papular skin lesion with a necrotic center at the tick bite site, accompanied by regional lymphadenopathy, myalgia, and flu-like symptoms. Ticks parasitizing both the patient and his dog were collected, along with the eschar. Two ticks were analyzed for Rickettsia isolation, and R. parkeri was successfully isolated from one infected specimen. The patient’s infection was confirmed by molecular testing through the PCR amplification of the gltA and ompA genes from an eschar inoculation sample. This represents the sixth confirmed case of rickettsiosis caused by R. parkeri in Brazil, and it reinforces the need for increased epidemiological surveillance in endemic regions for spotted fever caused by this pathogen. With the increasing recognition of R. parkeri in South America, further research is needed to better understand its transmission dynamics, clinical manifestations, and potential public health impact. Full article

This paper reports the first case in which a hyperlipidemic retriever (due to hypothyroidism) with a nasal tumor was successfully treated—achieving partial remission—and managed using a metronomic combination of chlorambucil (3.74 mg/m², SID) and prednisolone (0.28 mg/kg, SID) orally for 9 months at a general practice. A 35 kg spayed female golden retriever aged 8 years and 8 months with nosebleeds visited the Bundang New York Animal Hospital in July 2023 after being diagnosed with nasal carcinoma. A protocol of 4 weeks of chemotherapy followed by 1 week of rest was repeated in two cycles and continued metronomically for 9 months without pause after the two cycles. The nasal exudate was significantly reduced. The size of the nasal tumor was monitored using computed tomography (CT) imaging at a referral hospital. Since the first occurrence of epistaxis, 18 months have passed (as of January 2025) and the nasal exudate is barely visible, and the vital signs and weight of the dog remain stable. The size of the nasal tumor significantly decreased after 9 months of chemotherapy completion without moderate side effects, and all the blood work was normalized, including hypercholesteremia. This study demonstrates that, in hyperlipidemic cancer patients, a prednisolone/chlorambucil metronomic combination which is cost-effective can be an alternative to tyrosine kinase inhibitors such as sorafenib, even when excluding the price. Through a literature review, the author also investigates the effect of the hyperlipidemic state on cancer, focusing on carcinoma and vascular endothelial growth factor (VEGF), as well as the RAS-RAF-MEK pathway, which is a target for tyrosine kinase inhibitors, in order to reveal the molecular mechanism of chlorambucil metronomic chemotherapy. Also, the author investigates the molecular pathway of carcinoma development in human hyperlipidemia patients through single-cell RNA sequence analysis using open public data, and discusses the molecular action of chlorambucil. Full article

The aim of this work is to explore and understand the lived experience of nurses who chose to schedule visits with an Emotional Support Animal (ESA), i.e., a dog, during their working shift. Background/Objectives: Nursing practice is rigorous, weighted with intense responsibility that creates an environment conducive to stress and anxiety for the nurses, who have reported a higher level of work stress than other healthcare professionals. Knowing and addressing the factors impacting mental health/nurses’ well-being is crucial to providing care to patients. Stressful work environments result in burnout, compassion fatigue, depression, anxiety, suicide, and resignation. Understanding nurses’ perspectives on work related stress encourages hospitals to structure practices supporting nurses’ mental health and ability to provide quality care. Methods: A qualitative hermeneutic phenomenological approach was employed. Participants scheduled six weekly 10-min visits with Rex, a certified Service Dog for anxiety depression and PTSD, and registered ESA. A sample of 11 RNs participated in Rex visits at the workplace; field notes were taken during observations of visits. Semi-structured 30-min interviews conducted via Zoom, audio-recorded, and transcribed with NVivo were conducted. Results: Data were examined with Interpretative Phenomenological Analysis. Four main themes emerged: Preparing for the unknown, Doing the work, Refueling and resetting-Visits with Rex, What about nurses? Conclusions: This study highlights the need for nurses and hospital systems to incorporate self-care/self-reflection, including time/opportunities for nurses’ stress management during their practice. Knowledge of nurses receiving ESA interventions sheds light on how to protect/preserve the well-being of nurses practicing in this demanding profession. ESAs for nurses in the workplace offers an option to utilize dog therapy to re-energize and continue their shift renewed and refreshed. Full article

Purpose: Dirofilariasis is a zoonotic infectious disease caused by a species belonging to the Dirofilaria genus. Human dirofilariasis cases have increased in Europe in the last few decades. Dogs and wild canids represent the definitive hosts and principal reservoirs of Dirofilaria repens, while mosquito species are biological vectors. Humans act as accidental hosts, and clinical manifestations depend on the location of the worm in the organs or tissues. We described the first case of ocular dirofilariasis in the Aosta Valley region (Italy). Case description: a 62-year-old Italian woman complained of recurrent ocular redness, pain and discomfort, accompanied by itching and foreign body sensation in the right eye. The slit lamp biomicroscopic examination revealed conjunctival congestion on the temporal region of bulbar conjunctiva, and a long whitish vermiform mobile mass was detected under the conjunctiva. The anterior chamber showed no flare or cells in either eye, and the dilated fundus examination was normal. The worm was immediately surgically removed to prevent further migration, and was diagnosed morphologically and molecularly as D. repens. Following surgical removal, the symptoms resolved completely and rapidly, with no recurrence of ocular symptoms recorded during 12-month follow-up visits. Conclusions: Ocular dirofilariasis can lead to misdiagnosis due to its rare ocular manifestations, and it is considered an emergent zoonosis in European countries. Accurate diagnosis and control of ocular dirofilariasis by D. repens require a multidisciplinary approach under the One Health framework to effectively address this emergent zoonosis. Full article

Over the past decade, the number of companion dogs and cats has grown significantly, leading to an increase in veterinary visits. These visits can be stressful for animals, potentially affecting their long-term physical and emotional well-being. The aim of this study was to investigate how dog and cat owners perceive the factors influencing their pets’ behavior and welfare during veterinary visits. After completing a veterinary visit, dog and cat owners filled a survey assessing their pets’ behavioral responses at different stages of the consultation. A total of 94 dog and cat owners participated in this study. The findings revealed that perceived stress levels were the highest right after entering the practice but declined significantly after about 10 min in the waiting room. The owners’ observations, based on their familiarity with their pets’ typical behavior, were considered a useful tool for assessing the stress levels in their companion animals during the veterinary visits. Although they had the possibility to choose terms from a list of behaviors, no ethogram was provided previously or during the data collection. In conclusion, while stress remains a key concern for animal welfare, the most critical period identified was immediately before and after entering the veterinary practice. Further research is needed to better understand this crucial phase and its implications for the health and welfare of dogs and cats. Full article

This study selected green spaces from three residential areas in Hefei as the research subjects, combining behavioral observation methods and a natural experiment to collect behavioral data from 2010 and 2024. The data were then compared using Poisson regression models. Additionally, home visits were conducted to gather residents’ perceptions of the factors contributing to the decline in vitality. Based on the survey data, multilevel regression analysis was performed to explore the decline in RQGS usage vitality and its influencing factors in the context of rapid urbanization. This study found a significant decline in green space visits, particularly during the afternoon (16:00–18:00) and in areas adjacent to roadways. The main influencing factors include emerging leisure choices (such as taking the subway to large parks or preferring indoor activities) and residents’ satisfaction with RQGS characteristics (such as functional zoning, noise pollution, and neighborhood familiarity). Notably, there was no significant correlation between “disposable leisure time” and visit frequency. These findings suggest that, despite the inherent advantages of proximity, the vitality of RQGS faces increasing challenges due to emerging diverse leisure demands and growing environmental disturbances. In contrast to the traditional emphasis on accessibility, this study recommends that future RQGS planning prioritize functional zoning (e.g., dog-walking areas, sports zones), address the needs of vulnerable groups, and focus on mitigating vehicle noise and air pollution rather than merely expanding parking facilities. Interventions should be scheduled for the afternoon and emphasize strengthening community interaction and cohesion to enhance user experience. This research provides valuable scientific evidence and practical guidance for urban planners and policymakers to optimize residential green spaces in the context of rapid urbanization, offering new perspectives for the empirical evaluation of RQGS upgrades. Full article

Pugs are highly predisposed to corneal disorders, such as brachycephalic ocular syndrome (BOS), due to their disproportionate skull, reduced corneal sensitivity and eyelid anomalies such as distichiasis, entropion and lagophthalmos. The risk of corneal disorders which cause significant suffering is substantial, prompting calls for international efforts to reduce their prevalence. While these debilitating conditions are also likely to be common in pugs in Australia, their prevalence and risk factors have not been reported. The anonymised electronic patient records (EPRs) of 1318 pugs attending 139 primary care veterinary clinics participating in VetCompass Australia (VCA) in 2017 were used to investigate the prevalence of ophthalmological pathologies and associated demographic risk factors. Pugs were diagnosed with overweight/obesity (prevalence: 20.2%, 95% confidence interval {CI}: 18.1–22.4) ophthalmological abnormalities (14.5%, 95% CI: 12.6–16.3), particularly corneal disorders (12.4%, 95% CI: 12–15.7), and other conditions. The most prevalent ophthalmological disorders were corneal ulcers (5.5%, 95% CI: 4.4–6.9), corneal pigmentation (3.6%, 95% CI: 2.8–4.8) and keratoconjunctivitis sicca (KCS) (3.3%, 95% CI: 2.5–4.5). The risk of all corneal disorders increased with age (odds ratio 1.11, 95% CI: 1.07–1.15), and corneal pigmentation, KCS and keratitis were more prevalent in older pugs (a median age of 7.6 years or older), while entropion, neovascularisation and ulcerative keratitis affected younger dogs (a median age of 3 years or under). The underlying BOS conformation defects, exophthalmos, lagophthalmos and distichiasis, and early signs of corneal damage should be identified through detailed examinations during primary care veterinary visits, and affected pugs should be removed from the breeding population and treated to reduce the severity and duration of their suffering. Full article

(1) Each year, thousands of students leave their pets behind to attend university, often causing separation anxiety and losing a vital stress-coping resource. While many universities offer animal visitation programs (AVPs), their effectiveness in supporting student wellbeing during this transition remains unclear. This randomized controlled trial evaluated psychological mood risk and resilience in a randomly selected sample of first-year university students (n = 145) separated from their childhood pets. (2) Participants were randomly assigned to receive access to a seven-session, biweekly 2 h drop-in program (n = 77) featuring unstructured interactions with therapy dogs or a waitlist control group (n = 68). Assessments of wellbeing were conducted at the start, middle, and end of the semester including depression, anxiety, worry, stress, cognitive reappraisal, expressive suppression, and self-compassion. (3) Regression analyses showed that access to the semester-long drop-in program significantly flattened trajectories of depression (B = −3.05, p = 0.01, d = 0.514), worry (B = −3.92, p = 0.04, d = 0.416), and stress (B = −1.94, p = 0.05, d = 0.386) compared to the control group. Students in experimental conditions also showed improvements in self-compassion (B = 4.03, p < 0.001, d = 0.605). (4) These findings suggest regular access to unstructured drop-in programs featuring therapy dogs may provide valuable psychological support for students adjusting to university life. Full article

A cataract is a disease in which the lens of the eye becomes clouded, causing a partial or complete loss of vision. Phacoemulsification (PHACO) is a modern surgical technique used in cataract surgery. Study findings: This study observed changes in intraocular pressure (IOP) after surgery in 31 dogs (48 eyes) with cataracts that visited a veterinary hospital. The procedure involved a lens extraction by PHACO and the implantation of an intraocular lens (IOL). Postoperative ocular hypertension (POH) was defined as a postoperative IOP of 25 mmHg or higher. To assess changes in IOP, IOP measurements were performed at 1, 2, 3, and 20 h, and at 1, 2, 3, 4, and 8 weeks after surgery. The IOP was found to be significantly higher at 1 (p < 0.05), 2 (p < 0.01), and 3 (p < 0.01) hours postoperatively compared with preoperatively. The IOP measurements were compared by dividing them into three groups according to the observation period. The IOP values were measured for three groups: before cataract surgery (Group A: 13.10 ± 8.29 mmHg), 1 to 3 h after cataract surgery (Group B: 17.84 ± 5.33 mmHg), and 20 h to 8 weeks after surgery (Group C: 13.71 ± 4.78 mmHg). The IOP values from 1 to 3 h after surgery (Group B) were significantly higher compared to both Group A (p < 0.01) and Group C (p < 0.001). Conclusions: It is suggested that POH occurring within 0 to 3 h after cataract surgery should be diagnosed as secondary glaucoma, and treatment should be performed accordingly. Full article