Search Results (26)

The percentage of historical heritage buildings in Italy is substantial. Many of these buildings are abandoned or not adequately restored for public access due to safety concerns. However, some are managed by city councils and made available to local communities. These heritage buildings, valued for their historical significance, are now frequently used for live events, including musical performances by ensembles and small groups. This paper deals with the acoustics of two rooms provided with barrel-vaulted ceilings: Sisto V Hall in Naples and Aula Magna at the University of Parma. These spaces are structurally very similar, differing mainly in length. Acoustic measurements conducted in both halls reveal reverberation times of approximately 4.5 s at mid frequencies, resulting in poor speech clarity. This is primarily due to the presence of reflective surfaces, as the walls and ceilings are plastered, and the floors are tiled. To optimize their acoustic properties for functions such as celebrations, gatherings, and conferences, an acoustic design intervention was proposed. Digital models of the halls were calibrated and used to correct the acoustics by incorporating absorbing panels on the walls and carpeting on the floors of the central walk path. This treatment successfully balanced the reverberation time to approximately 1.3–1.4 s at mid frequencies, making speech more intelligible. Additionally, an amplified audio system was analyzed to enhance sound distribution, ensuring uniform coverage, even in the last rows of seating. Under amplified conditions, sound pressure levels (SPLs) range between 90 dB and 93 dB, with appropriate gain control applied to the column array speakers. Full article

The Ateneo Sueco del Socorro, built in 1927 in Sueca, Spain, is a prime example of the 20th-century architectural transformation, using reinforced concrete. Designed by architect Juan Guardiola, it reflects the Art Deco style, incorporating ornamental elements from Eastern civilizations. The building’s structure includes masonry walls, concrete columns, and vaulted ceilings. The building displayed a high level of damage due to the oxidation and corrosion of the reinforcements that compose the façade, which led to the definition of the most appropriate study and intervention methodology, applying contemporary tests for reinforced concrete. The original project’s structural design reflects the construction methods of its time, with sculptural elements using Fallas modeling techniques, resulting in various concrete and mortar types. After the façade presented a pathological condition in the early 21st century that made its restoration urgent, a study methodology was followed with current tests to accurately determine the lesions, their degree of damage, and compatible materials for restoration. Corrosion on the façade is mainly triggered by carbonation and the depassivation of reinforcements, exacerbated by environmental issues like moisture retention and oxygen permeability. Repairs should use compatible pre-mixed mortars, with surface inhibitors recommended to extend the lifespan of reinforcements. Full article

Villa Cicogna Mozzoni, located in Bisuschio near Varese and Lake Lugano, on the border between Lombardy and Switzerland, has origins dating back to the 1540s as a hunting lodge owned by the Mozzoni family. In the 16th century, significant renovations transformed it into a “villa di delizia”, adding gardens and elaborate decorative features to the interior and exterior, many of which are still preserved today. This article focuses on a precise geometric analysis of the building’s wooden ceilings, based on laser scanning and photogrammetric data surveying. The ongoing research particularly examines the wooden coffered ceilings on the first floor and the camorcanna wooden fake vault of the Grand Staircase of Honor. By analyzing the geometric data and comparing it with historical, archival, and recent manuals, the study has provided valuable morphological, construction, and conservation insights, forming the basis for the diagnostic and restoration project. Full article

Given the increasing prevalence of anxiety and depression, this research aims to identify design features that enhance the sense of restoration, with the goal of supporting mental and behavioral healthcare facility design. This study employed both screen-based and virtual reality (VR) stimuli to evaluate the perceived restorativeness of different interior settings. The key variables analyzed included window view access, view content, materiality, and room geometry. Thirty-five undergraduate and graduate students assessed 16 distinct interior environments. Findings indicate that the VR presentations generally produced higher restorativeness scores compared with screen-based presentations, though this effect varied across stimuli. Repeated-measures ANOVA revealed that larger windows consistently correlated with higher restorativeness scores in both presentation modes. Views of water were rated as most restorative, followed by wooded areas. Natural materials were perceived as significantly more restorative than other materials, particularly in VR presentations. Varied ceiling designs, especially vaulted ceilings, were associated with evaluations of higher restorativeness compared with flat ceiling designs, with this effect more pronounced in VR. This research underscores the potential of VR technology to simulate and assess interior design interventions, offering insights into creating more effective and personalized restorative environments in mental health treatment facilities. The findings can inform evidence-based design strategies for healthcare spaces, supporting treatment processes and patient well-being. Full article

Many heritage buildings from ancient Rome are being refurbished based on their original plan’s structure. One of them is the piscina mirabilis located nearby in Naples, which was a cistern used by the Romans to collect drinkable water for the navy waiting in the port of Misenum. The piscina mirabilis has similar architectural characteristics to a “cathedral”; however, its current precarious architectural state is the result of high levels of humidity that have caused the proliferation of mold on its vertical and horizontal surfaces over the centuries. Acoustic measurements were conducted inside the piscina mirabilis, highlighting an existing condition of the room being very reverberant, not suitable for occasional speech and conversations. The design proposed by the authors involves some mitigation solutions for the acoustics, mainly focused on controlling the low–medium frequencies and the realization of a restoration project consisting of a raised timber-floored walkway that runs along the perimeter walls, with the addition of water covering the existing floor as a natural element dominating the room volume, which represents the primary function of the building in antiquity. A waterfall was designed to be on the northern side wall. Acoustic studies were an important part of the refurbishment strategy, and a mitigation solution was devised to control medium–low frequencies by using inflated balloons of different sizes that were suspended from the ceiling vaults instead of widely used acoustic panels. The proposed strategy lowered the reverberation time by 3–4 s to accommodate a minimal level of conversational understanding. Such a solution is appropriate for this heritage building as well as other future conservation projects. Full article

Background: POP (pelvic organ prolapse) involves the descent of one or more pelvic organs downwards with or without protrusion from the vaginal opening, caused by the relaxation and weakening of ligaments, connective tissue, and pelvic muscles. Such an outcome negatively impacts the quality of life. The gold standard procedure for repairing apical compartment prolapse is colposacropexy (CS) to secure the anterior and posterior walls of the vagina to the anterior longitudinal sacral ligament, located anteriorly to the sacral promontory, using a mesh. Several surgical approaches are feasible. Laparotomic or minimally invasive methods, including laparoscopic or robotic ones, can restore the horizontal axis of the vagina and typically involve concomitant hysterectomy. Methods: This study is based on 80 patients who underwent CS at Palermo’s Ospedali Riuniti Villa Sofia-Cervello from 2019 to 2023. Women aged 35–85 at the time of surgery were divided into two groups: 40 patients underwent mini-laparoscopic surgery, and 40 patients underwent robotic surgery. The following parameters were accounted for: demographic data (initials of name and surname, age), preoperative clinical diagnosis, date of surgery, surgical procedure performed, estimated intraoperative blood loss, duration of surgical intervention, length of hospital stay, postoperative pain assessed at 24 h using the VAS scale, and any complications occurring in the postoperative period. Mini-laparoscopic CS (Minilap) and robotic CS (Rob) were then compared in terms of outcomes. Results: In the Minilap group, 11 patients out of 40 had a preoperative diagnosis of vaginal vault prolapse. The average age in this group was 61.6. Five of these patients had isolated cystocele, while the rest presented vaginal stump prolapse linked to cystocele, rectocele, or both. The remaining 29 patients in the Minilap group had a preoperative diagnosis of uterovaginal prolapse, also associated with cystocele, rectocele, or both, or isolated in nine cases. In the Rob group (average age: 60.1), 13 patients were diagnosed with vaginal prolapse (isolated or associated with cystocele), while the remaining 27 had a diagnosis of uterovaginal prolapse. In the Minilap group, the average procedure duration was 123.3 min, shorter than the Rob group (160.1 min). Conclusions: The data collected throughout this prospective study point to the mini-laparoscopic approach as being preferable over the robotic one in terms of surgical procedure length, intraoperative blood loss, postoperative pain, and aesthetic outcome. Hospital stay duration and post operative complication rates were similar for both groups. The innovative and ever-progressing nature of such procedures calls for novel standards prioritizing patient care as well as medicolegal viability. Full article

The 2020 Zagreb earthquake caused extensive damage to historically significant buildings, including the Cathedral of the Assumption of Mary, a key monument of Croatian cultural heritage. The earthquake rendered the cathedral unsafe due to significant damage to its towers and numerous cracks in its vaults and walls. Urgent measures were necessary to ensure safety and facilitate planned reconstruction and strengthening efforts. A specialised scaffolding design was developed to support inaccessible and unstable areas, involving over 1000 tonnes of steel. This paper details the structural concepts and specific scaffolding design implemented for the urgent restoration and seismic retrofitting of Zagreb Cathedral, ensuring it meets high earthquake resistance requirements. Full article

This paper reports the investigation of six microsamples collected from the vault of the San Panfilo Church in Tornimparte (AQ). The aim was to detect the composition of the pigments and protective/varnishes, and to investigate the executive technique, the conservation state, and the evidence of the restoration works carried out in the past. Six microsamples were analyzed by optical microscopy, scanning electron microscopy coupled with energy-dispersive spectroscopy (EDS), X-ray fluorescence (XRF), and infrared and Raman spectroscopy. The investigations were carried out within the framework of the Tornimparte project “Archeometric investigation of the pictorial cycle of Saturnino Gatti in Tornimparte (AQ, Italy)” sponsored in 2021 by the Italian Association of Archeometry (AIAr). Full article

Salt crystallization is one of the most dangerous forms of degradation affecting frescoes. This phenomenon can lead to cracking, flaking and detachment of the pictorial layer, ultimately ruining the work of art. However, the characterization of soluble salts via chemical analysis can be employed to determine the conditions of the artifact and establish the proper restoration and/or conservation strategies to be adopted. In this archaeometric study, a first-ever characterization of the soluble salts and related degradation phenomena on the frescoes by Saturnino Gatti in the church of San Panfilo in Villagrande di Tornimparte (L’Aquila) was carried out. Sampling was performed in areas with evident detachments, exfoliations and saline crystallization (efflorescences). Eleven samples of powder and fragments were taken from different panels of the fresco: nine were taken from Panels A, C, D and E and two from the top part of the vault. Chemical characterizations were performed using two analytical techniques: ion chromatography (IC) and attenuated total reflectance Fourier-transform infrared spectroscopy (ATR-FTIR). Ion chromatography was used for the quantification of the main ions and to evaluate the presence of soluble salts, whereas infrared spectroscopy was used to characterize the mineralogical phases. The results show efflorescence consisting of newly formed gypsum and carbonate in samples taken closer to the ground. Furthermore, a good correlation between sodium and chloride ions was observed, indicating the presence of an efflorescence composed of newly formed sodium chloride. Capillary rise and infiltration were highlighted as the main sources of soluble salts. This information will be crucial in guiding future restoration or conservation operations. Full article

This paper provides the results of a 3D photogrammetric survey of the apsidal conch of St. Panfilo Church in Tornimparte (L’Aquila, Italy). The images were acquired and then processed in order to obtain a three-dimensional model available on Sketchfab platform. The five panels and the vault of the apsidal conch were exported from the 3D model as orthomosaics and then imported into CAD software for the mapping of the main degradation phenomena. The examined surface was almost entirely covered by mural painting and restoring mortars, the latter mainly located in the lower part of the apsidal conch. The whole surface of the apsidal conch was also examined by means of raking light that enabled highlighting of conservation problems and the presence of incision marks and giornata/pontate boundaries indicating the use of the fresco painting technique. Several degradation phenomena, attributable both to the executive technique of wall painting and the microclimate conditions, could be observed. According to the overlapping of weathering forms and the material involved, most of the examined surfaces exhibited moderate to very severe degradation. Full article

One of the most important castles of the medieval Teutonic Order—Riga Castle in Latvia—is currently undergoing extensive reconstruction work. This study attempts to summarize recent information about the medieval fresco in the chapel and decorative paintings (17th century CE) on the vaults and vault consoles of the refectory that were found during this work. The restorers acquired a combined knowledge of the materials during the pre-restoration research as well as during the restoration process. This, together with the art historian’s viewpoint, and analytical study conducted by chemical technologist of art restoration and material scientists, allowed for an understanding of the materials present, as well as for a determination of the most probable techniques used for the creation of the frescoes. Based on the results presented in this study, the investigated fresco was mostly created using local materials for the plaster and imported ones for pigments, specifically azurite, malachite, and cinnabar. The restoration works, and the possible iconographic meaning of the remaining fragments of the medieval painting, are also discussed. Full article

Parametric design, algorithmic modeling, generative design, and associative design are only some of the keywords of a work paradigm that is becoming more and more popular, designed to respond to the complexities of contemporary architecture. Most commonly, such an approach is used for new buildings, but when algorithmic design meets heritage building information modeling (HBIM), the process can take on an even greater centrality—flexibility and control go hand-in-hand, ensuring precious tools for the planning of restoration interventions and management projects. This contribution, oriented to expand the use of these strategies to heritage, deals with the theme of parametric modeling of masonry vaults, a structural–architectural feature that in many forms and combinations characterizes most historic buildings. In particular, the connection of BIM software with algorithmic modeling software can allow the ‘translation’ of complex geometric shapes into elements with full Level of Detail elements (LOD 500) while preserving, at the same time, the algorithmic editing functions. In this paper, it is illustrated as this approach permits the finetuning of the vaults’ details, from time to time, based on different survey strategies (e.g., direct measurements, experimental tests, laser scanners, etc.). In other words, using this new connection in real time, architects can design restoration interventions tied to shapes, geometries, and masonry peculiarities that would otherwise be impossible to manage. An updatable virtualization of the actual state of a heritage building thus becomes affordable for the wider public (LOD G). There is also a valuable benefit for the heritage stakeholders in terms of protection of the architectural value and conscious planning in the restoration practice, especially in the museum field. Full article

In the presence of architecturally significant ruins, restoring and disseminating the idea of a testimony that has survived the destructive work of time is a cultural and social necessity that the use of advanced methods and tools allows to communicate in a timely and comprehensive manner. The integration of 3D surveying techniques and digital information production and management processes (graphic and alphanumeric, i.e., geometric information) makes it possible to put in place multifaceted and effective strategies. The article aims at describing the process of data acquisition (using applied photogrammetry) of the remains of a medieval cloister located on the outskirts of ancient Oppido Mamertina (RC, Italy). The use of the acquired point cloud, cleaned and optimised, made it possible to extract suitable orthophotos from which to derive the matrix profiles of the vaulted roof system. The information organisation of the model, which can be queried on time despite the generic level of detail, leads us to meditate on the change taking place in the field of documentation for urban environmental design and maintenance. Full article

Oncogenic drivers such as mutated EGFR are the preferred targets in modern drug development. However, restoring the lost function of tumor suppressor proteins could also be a valid approach to combatting cancer. ITIH5 has been revealed as a potent metastasis suppressor in both breast and pancreatic cancer. Here, we show that ITIH5 overexpression in MDA-MB-231 breast cancer cells can also locally suppress tumor growth by 85%, when transplanted into the mammary fat pad of nude mice. For a potential drug development approach, we further aimed to define downsized ITIH5 polypeptides that still are capable of mediating growth inhibitory effects. By cloning truncated and His-tagged ITIH5 fragments, we synthesized two recombinant N-terminal polypeptides (ITIH5^681aa and ITIH5^161aa), both covering the ITI heavy chain specific “vault protein inter-alpha-trypsin” (VIT) domain. Truncated ITIH5 variants caused dose-dependent cell growth inhibition by up to 50% when applied to various cancer cell lines (e.g., MDA-MB-231, SCaBER, A549) reflecting breast, bladder and lung cancer in vitro. Thus, our data suggest the substantial role of the ITIH5-specific VIT domain in ITIH5-mediated suppression of tumor cell proliferation. As extracellularly administered ITIH5 peptides mimic the growth-inhibitory effects of the full-length ITIH5 tumor suppressor protein, they may constitute the basis for developing anticancer drugs in the future. Full article

This research presents a new intervention methodology on arches and vaults of a Renaissance factory in the Colegio Santo Domingo de Orihuela (16th century) using 3D software LIDAR technology that verifies the execution process of the works studying the different charges states and structure behavior. This document aims to explain a working methodology in the monitoring of structural repair interventions in the architectural heritage, in the specific case of the replacement of traditional one-way timber joist frame slabs on structures of former, splay and groin arches between vaults. This involves the compilation and processing of two types of data: on the one hand, the analysis of the different load states to which the intervention is exposed in its different phases: initial, dismantling of the different layers of traditional construction and replacement by the new structural system; and, on the other hand, the graphic information provided by the photogrammetry techniques used to dimension and define the spatial position of the structural elements that have historically resolved the covering of the architectural space in this type of Renaissance solution. The different layers and demolished materials have been verified by analysing their constructive disposition, thicknesses, and dimensions of the elements that formed part of the initial construction system and their own weights. In addition, the new construction systems used in the restoration project generate a state of loads similar to the existing one. The LIDAR technology used in the research process provides graphic data of the spatial position of the arches and vaults studied in the different states of the construction intervention. The point clouds obtained are analysed by taking as reference fixed points (considered unalterable and infinitely rigid) of the refectory and the coordinates of the initial and final states are compared. The results show minimal variations between the two positions, which justifies the goodness of the construction methods used and the structural safety obtained in the complex. This methodology applied to arches and vaults in heritage architecture guarantees the control and recording of the movements produced in the process. Full article