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Keywords = two-photon process

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25 pages, 9127 KiB  
Article
Applicability and Design Considerations of Chaotic and Quantum Entropy Sources for Random Number Generation in IoT Devices
by Wieslaw Marszalek, Michał Melosik, Mariusz Naumowicz and Przemysław Głowacki
Entropy 2025, 27(7), 726; https://doi.org/10.3390/e27070726 - 4 Jul 2025
Viewed by 229
Abstract
This article presents a comparative analysis of two types of generators of random sequences: one based on a discrete chaotic system being the logistic map, and the other being a commercial quantum random number generator QUANTIS-USB-4M. The results of the conducted analysis serve [...] Read more.
This article presents a comparative analysis of two types of generators of random sequences: one based on a discrete chaotic system being the logistic map, and the other being a commercial quantum random number generator QUANTIS-USB-4M. The results of the conducted analysis serve as a guide for selecting the type of generator that is more suited for a specific IoT solution, depending on the functional profile of the target application and the amount of random data required in the cryptographic process. This article discusses both the theoretical foundations of chaotic phenomena underlying the pseudorandom number generator based on the logistic map, as well as the theoretical principles of photon detection used in the quantum random number generators. A hardware IP Core implementing the logistic map was developed, suitable for direct implementation either as a standalone ASIC using the SkyWater PDK process or on an FPGA. The generated bitstreams from the implemented IP Core were evaluated for randomness. The analysis of the entropy levels and evaluation of randomness for both the logistic map and the quantum random number generator were performed using the ent tool and NIST test suite. Full article
(This article belongs to the Section Multidisciplinary Applications)
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11 pages, 1984 KiB  
Article
High-Resolution DLP 3D Printing for Complex Curved and Thin-Walled Structures at Practical Scale: Archimedes Microscrew
by Chih-Lang Lin, Jun-Ting Liu and Chow-Shing Shin
Micromachines 2025, 16(7), 762; https://doi.org/10.3390/mi16070762 - 29 Jun 2025
Viewed by 233
Abstract
As three-dimensional (3D) printing becomes increasingly prevalent in microfluidic system fabrication, the demand for high precision has become critical. Among various 3D printing technologies, light-curing-based methods offer superior resolution and are particularly well suited for fabricating microfluidic channels and associated micron-scale components. Two-photon [...] Read more.
As three-dimensional (3D) printing becomes increasingly prevalent in microfluidic system fabrication, the demand for high precision has become critical. Among various 3D printing technologies, light-curing-based methods offer superior resolution and are particularly well suited for fabricating microfluidic channels and associated micron-scale components. Two-photon polymerization (TPP), one such method, can achieve ultra-high resolution at the submicron level. However, its severely limited printable volume and high operational costs significantly constrain its practicality for real-world applications. In contrast, digital light processing (DLP) 3D printing provides a more balanced alternative, offering operational convenience, lower cost, and print dimensions that are more compatible with practical microfluidic needs. Despite these advantages, most commercial DLP systems still struggle to fabricate intricate, high-resolution structures—particularly curve, thin-walled, or hollow ones—due to over-curing and interlayer adhesion issues. In this study, we developed a DLP-based projection micro-stereolithography (PμSL) system with a simple optical reconfiguration and fine-tuned its parameters to overcome limitations in printing precise and intricate structures. For demonstration, we selected an Archimedes microscrew as the target structure, as it serves as a key component in microfluidic micromixers. Based on our previous study, the most effective design was selected and fabricated in accordance with practical microfluidic dimensions. The PμSL system developed in this study, along with optimized parameters, provides a reference for applying DLP 3D printing in high-precision microfabrication and advancing microfluidic component development. Full article
(This article belongs to the Special Issue Recent Advances in Micro/Nanofabrication, 2nd Edition)
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13 pages, 4454 KiB  
Article
Proton Irradiation and Thermal Restoration of SiPMs for LEO Missions
by Alexis Luszczak, Lucas Finazzi, Leandro Gagliardi, Milagros Moreno, Maria L. Ibarra, Federico Golmar and Gabriel A. Sanca
Instruments 2025, 9(3), 15; https://doi.org/10.3390/instruments9030015 - 26 Jun 2025
Viewed by 219
Abstract
Silicon Photomultipliers (SiPMs) are optical sensors widely used in space applications due to their high photon detection efficiency, low power consumption, and robustness. However, in Low Earth Orbit (LEO), their performance degrades over time due to prolonged exposure to ionizing radiation, primarily from [...] Read more.
Silicon Photomultipliers (SiPMs) are optical sensors widely used in space applications due to their high photon detection efficiency, low power consumption, and robustness. However, in Low Earth Orbit (LEO), their performance degrades over time due to prolonged exposure to ionizing radiation, primarily from trapped protons and electrons. The dominant radiation-induced effect in SiPMs is an increase in dark current, which can compromise detector sensitivity. This study investigates the potential of thermal annealing as a mitigation strategy for radiation damage in SiPMs. We designed and tested PCB-integrated heaters to selectively heat irradiated SiPMs and induce recovery processes. A PID-controlled system was developed to stabilize the temperature at 100 °C, and a remotely controlled experimental setup was implemented to operate under irradiation conditions. Two SiPMs were simultaneously irradiated with 9 MeV protons at the EDRA facility, reaching a 1 MeV neutron equivalent cumulative fluence of (9.5 ± 0.2) × 108 cm−2. One sensor underwent thermal annealing between irradiation cycles, while the other served as a control. Throughout the experiment, dark current was continuously monitored using a source measure unit, and I–V curves were recorded before and after irradiation. A recovery of more than 39% was achieved after only 5 min of thermal cycling at 100 °C, supporting this recovery approach as a low-complexity strategy to mitigate radiation-induced damage in space-based SiPM applications and increase device lifetime in harsh environments. Full article
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22 pages, 9227 KiB  
Review
Review: The Application of MXene in Thermal Energy Storage Materials for Efficient Solar Energy Utilization
by Han Sun, Yingai Jin and Firoz Alam
Materials 2025, 18(12), 2839; https://doi.org/10.3390/ma18122839 - 16 Jun 2025
Viewed by 388
Abstract
Two-dimensional transition metal carbides/nitrides (MXenes) have shown potential in biosensors, cancer theranostics, microbiology, electromagnetic interference shielding, photothermal conversion, and thermal energy storage due to their unique electronic structure, ability to absorb a wide range of light, and tunable surface chemistry. In spite of [...] Read more.
Two-dimensional transition metal carbides/nitrides (MXenes) have shown potential in biosensors, cancer theranostics, microbiology, electromagnetic interference shielding, photothermal conversion, and thermal energy storage due to their unique electronic structure, ability to absorb a wide range of light, and tunable surface chemistry. In spite of the growing interest in MXenes, there are relatively few studies on their applications in phase-change materials for enhancing thermal conductivity and weak photo-responsiveness between 0 °C and 150 °C. Thus, this study aims to provide a current overview of recent developments, to examine how MXenes are made, and to outline the combined effects of different processes that can convert light into heat. This study illustrates the mechanisms that include enhanced broadband photon harvesting through localized surface plasmon resonance, electron–phonon coupling-mediated nonradiative relaxation, and interlayer phonon transport that optimizes thermal diffusion pathways. This study emphasizes that MXene-engineered 3D thermal networks can greatly improve energy storage and heat conversion, solving important problems with phase-change materials (PCMs), like poor heat conductivity and low responsiveness to light. This study also highlights the real-world issues of making MXene-based materials on a large scale, and suggests future research directions for using them in smart thermal management systems and solar thermal grid technologies. Full article
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11 pages, 2010 KiB  
Article
Metasurface-Enhanced Infrared Photodetection Using Layered van der Waals MoSe2
by Jinchun Li, Zhixiang Xie, Tianxiang Zhao, Hongliang Li, Di Wu and Xuechao Yu
Nanomaterials 2025, 15(12), 913; https://doi.org/10.3390/nano15120913 - 12 Jun 2025
Viewed by 407
Abstract
Transition metal dichalcogenide (TMD) materials have demonstrated promising potential for applications in photodetection due to their tunable bandgaps, high carrier mobility, and strong light absorption capabilities. However, limited by their intrinsic bandgaps, TMDs are unable to efficiently absorb photons with energies below the [...] Read more.
Transition metal dichalcogenide (TMD) materials have demonstrated promising potential for applications in photodetection due to their tunable bandgaps, high carrier mobility, and strong light absorption capabilities. However, limited by their intrinsic bandgaps, TMDs are unable to efficiently absorb photons with energies below the bandgap, resulting in a significant attenuation of photoresponse in spectral regions beyond the bandgap. This inherently restricts their broadband photodetection performance. By introducing metasurface structures consisting of subwavelength optical elements, localized plasmon resonance effects can be exploited to overcome this absorption limitation, significantly enhancing the light absorption of TMD films. Additionally, the heterogeneous integration process between the metasurface and two-dimensional materials offers low-temperature compatibility advantages, effectively avoiding the limitations imposed by high-temperature doping processes in traditional semiconductor devices. Here, we systematically investigate metasurface-enhanced two-dimensional MoSe2 photodetectors, demonstrating broadband responsivity extension into the mid-infrared spectrum via precise control of metasurface structural dimensions. The optimized device possesses a wide spectrum response ranging from 808 nm to 10 μm, and the responsivity (R) and specific detection rate (D*) under 4 μm illumination achieve 7.1 mA/W and 1.12 × 108 Jones, respectively. Distinct metasurface configurations exhibit varying impacts on optical absorption characteristics and detection spectral ranges, providing experimental foundations for optimizing high-performance photodetectors. This work establishes a practical pathway for developing broadband optoelectronic devices through nanophotonic structure engineering. Full article
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19 pages, 1706 KiB  
Article
Demonstration of 50 Gbps Long-Haul D-Band Radio-over-Fiber System with 2D-Convolutional Neural Network Equalizer for Joint Phase Noise and Nonlinearity Mitigation
by Yachen Jiang, Sicong Xu, Qihang Wang, Jie Zhang, Jingtao Ge, Jingwen Lin, Yuan Ma, Siqi Wang, Zhihang Ou and Wen Zhou
Sensors 2025, 25(12), 3661; https://doi.org/10.3390/s25123661 - 11 Jun 2025
Viewed by 382
Abstract
High demand for 6G wireless has made photonics-aided D-band (110–170 GHz) communication a research priority. Photonics-aided technology integrates optical and wireless communications to boost spectral efficiency and transmission distance. This study presents a Radio-over-Fiber (RoF) communication system utilizing photonics-aided technology for 4600 m [...] Read more.
High demand for 6G wireless has made photonics-aided D-band (110–170 GHz) communication a research priority. Photonics-aided technology integrates optical and wireless communications to boost spectral efficiency and transmission distance. This study presents a Radio-over-Fiber (RoF) communication system utilizing photonics-aided technology for 4600 m long-distance D-band transmission. We successfully show the transmission of a 50 Gbps (25 Gbaud) QPSK signal utilizing a 128.75 GHz carrier frequency. Notwithstanding these encouraging outcomes, RoF systems encounter considerable obstacles, including pronounced nonlinear distortions and phase noise related to laser linewidth. Numerous factors can induce nonlinear impairments, including high-power amplifiers (PAs) in wireless channels, the operational mechanisms of optoelectronic devices (such as electrical amplifiers, modulators, and photodiodes), and elevated optical power levels during fiber transmission. Phase noise (PN) is generated by laser linewidth. Despite the notable advantages of classical Volterra series and deep neural network (DNN) methods in alleviating nonlinear distortion, they display considerable performance limitations in adjusting for phase noise. To address these problems, we propose a novel post-processing approach utilizing a two-dimensional convolutional neural network (2D-CNN). This methodology allows for the extraction of intricate features from data preprocessed using traditional Digital Signal Processing (DSP) techniques, enabling concurrent compensation for phase noise and nonlinear distortions. The 4600 m long-distance D-band transmission experiment demonstrated that the proposed 2D-CNN post-processing method achieved a Bit Error Rate (BER) of 5.3 × 10−3 at 8 dBm optical power, satisfying the soft-decision forward error correction (SD-FEC) criterion of 1.56 × 10−2 with a 15% overhead. The 2D-CNN outperformed Volterra series and deep neural network approaches in long-haul D-band RoF systems by compensating for phase noise and nonlinear distortions via spatiotemporal feature integration, hierarchical feature extraction, and nonlinear modelling. Full article
(This article belongs to the Special Issue Recent Advances in Optical Wireless Communications)
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15 pages, 18796 KiB  
Article
Study of the Repair Action and Mechanisms of a Moisturizing Cream on an SLS-Damaged Skin Model Using Two-Photon Microscopy
by Yixin Shen, Ying Ye, Lina Wang, Huiping Hu, Caixia Wang, Yuxuan Wu, Dingqiao Lin, Jiaqi Shen, Hong Zhang, Yanan Li and Peiwen Sun
Cosmetics 2025, 12(3), 119; https://doi.org/10.3390/cosmetics12030119 - 10 Jun 2025
Viewed by 787
Abstract
This study evaluates the efficacy of a novel moisturizing cream using a sodium lauryl sulfate (SLS)-induced skin damage model, supported by advanced imaging with two-photon microscopy (TPM). TPM’s capabilities allow for in-depth, non-invasive visualization of skin repair processes, surpassing traditional imaging methods. The [...] Read more.
This study evaluates the efficacy of a novel moisturizing cream using a sodium lauryl sulfate (SLS)-induced skin damage model, supported by advanced imaging with two-photon microscopy (TPM). TPM’s capabilities allow for in-depth, non-invasive visualization of skin repair processes, surpassing traditional imaging methods. The innovative formulation of the cream includes ceramide NP, ceramide NS, ceramide AP, lactobacillus/soybean ferment extract, and bacillus ferment, targeting the enhancement of skin hydration, barrier function, and structural integrity. In SLS-stimulated 3D skin models and clinical settings, the cream significantly improved the expression of key barrier proteins such as filaggrin (FLG), loricrin (LOR), and transglutaminase 1 (TGM1), while reducing inflammatory markers like IL-1α, TNF-α, and PGE2. Notably, the cream facilitated a significant increase in epidermal thickness and improved the dermal–epidermal junction index (DEJI), as observed through TPM, indicating profound skin repair and enhanced barrier functionality. Clinical trials further demonstrated the cream’s reparative effects, significantly reducing symptoms in participants with sensitive skin and post-intense pulsed light (IPL) treatment scenarios. This study highlights the utility of TPM as a groundbreaking tool in cosmetic dermatology, offering real-time analysis of the effects of skincare products on skin structure and function. Full article
(This article belongs to the Section Cosmetic Dermatology)
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9 pages, 9851 KiB  
Article
Manipulation of Topological Edge States and Realization of Zero-Dimensional Higher-Order Topological Point States
by Jiahui Ren, Wenjing Ding, Sihan Wang and Shiwei Tang
Micromachines 2025, 16(6), 686; https://doi.org/10.3390/mi16060686 - 7 Jun 2025
Viewed by 447
Abstract
Topological photonics has provided revolutionary ideas for the design of next-generation photonic devices due to its unique light transmission properties. This paper proposes a honeycomb photonic crystal structure based on a mirror-symmetric interface and numerically simulates the precise manipulation of topological edge states [...] Read more.
Topological photonics has provided revolutionary ideas for the design of next-generation photonic devices due to its unique light transmission properties. This paper proposes a honeycomb photonic crystal structure based on a mirror-symmetric interface and numerically simulates the precise manipulation of topological edge states and the robust excitation of high-order topological corner states in this structure. Specifically, two honeycomb photonic crystals with non-trivial topological properties form an interface through mirror-symmetric stitching. Continuous adjustment of the spacing between their coupling pillars can induce the closure and reopening of topological edge state energy bands, accompanied by significant band inversion, revealing the dynamic process of topological phase transitions. Furthermore, zero-dimensional high-order topological corner states are observed at the junction of boundaries with different topological properties. Their localized field strengths are strictly confined and exhibit strong robustness against structural defects. This study not only provides a new mechanism for the local symmetry manipulation of topological edge states but also lays a foundation for the design of high-order topological photonic crystals and the practical application of topological photonic devices. Full article
(This article belongs to the Special Issue Novel Electromagnetic and Acoustic Devices)
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14 pages, 2006 KiB  
Article
Design and Optimization of Optical NAND and NOR Gates Using Photonic Crystals and the ML-FOLD Algorithm
by Alireza Mohammadi, Fariborz Parandin, Pouya Karami and Saeed Olyaee
Photonics 2025, 12(6), 576; https://doi.org/10.3390/photonics12060576 - 6 Jun 2025
Viewed by 516
Abstract
The continuous demand for faster processing systems, driven by the rise of artificial intelligence, has exposed limitations in traditional transistor-based electronics, including quantum tunneling, heat dissipation, and switching delays due to challenges in further miniaturization. This study explores optical systems as a promising [...] Read more.
The continuous demand for faster processing systems, driven by the rise of artificial intelligence, has exposed limitations in traditional transistor-based electronics, including quantum tunneling, heat dissipation, and switching delays due to challenges in further miniaturization. This study explores optical systems as a promising alternative, leveraging the speed of photons over electrons. Specifically, we design and simulate optical NAND and NOR logic gates using a two-dimensional photonic crystal structure with a square lattice. Symmetrical waveguides are used for the input paths to make the structure relatively more straightforward to fabricate. A key innovation is the ability to realize both gates within a single structure by adjusting the phases of the input sources. To optimize the phase parameters efficiently, we employ the ML-FOLD (Meta-Learning and Formula Optimization for Logic Design) optimization formula, which outperforms traditional methods and machine learning approaches in terms of computational efficiency and data requirements. Through finite-difference time-domain (FDTD) simulations, the proposed optical structure demonstrates successful implementation of NAND and NOR gate logic, achieving high contrast ratios of 4.2 dB and 4.8 dB, respectively. The results validate the effectiveness of the ML-FOLD method in identifying optimal configurations, offering a streamlined approach for the design of all-optical logic devices. Full article
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11 pages, 1024 KiB  
Article
Parametric Interaction-Induced Asymmetric Behaviors in a Coupled-Cavities Quantum Electrodynamics System
by Xu Ma, Dexi Guo, Chengjie Zhu and Jingping Xu
Photonics 2025, 12(6), 563; https://doi.org/10.3390/photonics12060563 - 4 Jun 2025
Viewed by 338
Abstract
We investigate a quantum electrodynamics system consisting of two coupled single-mode cavities. The left cavity couples with a two-level atom, while the right cavity incorporates a second-order nonlinear medium, activated by a pumping field. In the absence of nonlinear medium, we show that [...] Read more.
We investigate a quantum electrodynamics system consisting of two coupled single-mode cavities. The left cavity couples with a two-level atom, while the right cavity incorporates a second-order nonlinear medium, activated by a pumping field. In the absence of nonlinear medium, we show that the transmitted field intensity reveals only classical asymmetric behavior at the central frequency. However, the parametric interaction induced by the nonlinear medium leads to various quantum asymmetric behaviors at single photon excitation frequencies, including the squeezing, quantum statistics, and phase-space characteristics of the transmitted photons. These asymmetric behaviors arise from additional excitation pathways enabled by the parametric interaction-induced two-photon processes. We demonstrate these asymmetric behaviors through Klyshko’s figures of merit, the Wigner function, and the steady-state second-order correlation function of the transmitted photons. These results present promising applications for remote quantum-state manipulation and contribute significantly to the advancement of quantum networking. Full article
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23 pages, 4102 KiB  
Article
Analysis and Validation of the Signal-to-Noise Ratio for an Atmospheric Humidity Profiling Spectrometer Based on 1D-Imaging Spatial Heterodyne Spectroscopy
by Shaochun Xie, Haiyan Luo, Zhiwei Li, Wei Jin, Qiong Wu, Mai Hu, Yang Hong and Wei Xiong
Remote Sens. 2025, 17(11), 1810; https://doi.org/10.3390/rs17111810 - 22 May 2025
Viewed by 410
Abstract
Sub-kilometer spatial resolution humidity profiles from the stratosphere to the mesosphere are essential for investigating the function of atmospheric water vapor in the global water and energy cycles as well as in radiation transport. The significant variations in atmospheric radiation at low altitudes [...] Read more.
Sub-kilometer spatial resolution humidity profiles from the stratosphere to the mesosphere are essential for investigating the function of atmospheric water vapor in the global water and energy cycles as well as in radiation transport. The significant variations in atmospheric radiation at low altitudes and the gradual changes at high altitudes pose challenges to the data acquisition and processing methods of limb imaging spectrometers that rely on atmospheric scattering and absorption mechanisms. In this paper, the effects of two binning techniques—interferogram binning and recovered spectrum binning—on improving the spectral signal-to-noise ratio (SNR) are examined through theoretical analysis and simulations, exemplified by a one-dimensional (1D) imaging spatial heterodyne spectrometer designed for measuring atmospheric humidity profiles. Rician random variables are employed to characterize the amplitude of the recovered spectral points under varying signal conditions, from which spectral SNR expressions are derived for both binning methods. The difference in both methods is evaluated through numerical simulations and experiments. Simulation results demonstrate that, with an integration time of 0.3 s and a spectral resolution of 0.03 nm, the input signal below 50 km is strong, with photon noise being the dominant factor, and both binning methods improve SNR proportionally to the square root of the number of binned rows. As the signal weakens above 50 km, additive noise gradually becomes dominant with increasing tangent altitude, and spectrum binning yields a higher SNR than interferogram binning. Experimental data obtained from a similar type of spectrometer further validate these simulation findings. The results indicate that spectrum binning provides greater advantages in improving the SNR for detecting water vapor in the mesosphere, paving the way for achieving a higher vertical resolution in subsequent retrievals. Full article
(This article belongs to the Special Issue Optical Remote Sensing Payloads, from Design to Flight Test)
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38 pages, 9782 KiB  
Review
Laser-Fabricated Micro/Nanostructures: Mechanisms, Fabrication Techniques, and Applications
by Andrei Teodor Matei, Anita Ioana Visan and Irina Negut
Micromachines 2025, 16(5), 573; https://doi.org/10.3390/mi16050573 - 13 May 2025
Viewed by 1110
Abstract
The rapid evolution of optoelectronic devices necessitates innovative fabrication techniques to improve their performance and functionality. This review explores the advancements in laser processing as a versatile method for creating micro- and nanostructured surfaces, tailored to enhance the efficiency of optoelectronic applications. We [...] Read more.
The rapid evolution of optoelectronic devices necessitates innovative fabrication techniques to improve their performance and functionality. This review explores the advancements in laser processing as a versatile method for creating micro- and nanostructured surfaces, tailored to enhance the efficiency of optoelectronic applications. We begin by elucidating the fundamental mechanisms underlying laser interactions with materials, which facilitate the precise engineering of surface topographies. Following this, we systematically review various micro/nanostructures fabricated by laser techniques, such as laser ablation, laser-induced periodic surface structures (LIPSS), and two-photon polymerization, highlighting their unique properties and fabrication parameters. The review also delves into the significant applications of these laser-fabricated surfaces in optoelectronic devices, including photovoltaics, photodetectors, and sensors, emphasizing how tailored surface structures can lead to improved light absorption, enhanced charge carrier dynamics, and optimized device performance. By synthesizing current knowledge and identifying emerging trends, this work aims to inspire future research directions in the design and application of laser-fabricated micro/nanostructures within the field of optoelectronics. Our findings underscore the critical role of laser technology in advancing the capabilities of next-generation optoelectronic devices, aligning with the scope of emerging trends in device engineering. Full article
(This article belongs to the Special Issue Emerging Trends in Optoelectronic Device Engineering)
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12 pages, 2382 KiB  
Article
Index-Matching Two-Photon Polymerization for Enhancing Machining Accuracy of Diffractive Neural Networks
by Mabiao Fu, Xiaoguang Ma, Weihong Shen, Ruojing Ren and Qiming Zhang
Photonics 2025, 12(5), 473; https://doi.org/10.3390/photonics12050473 - 12 May 2025
Viewed by 372
Abstract
Two-photon polymerization (TPP) is an effective and rapid method for prototyping diffractive neural networks (DNNs). However, DNNs’ accuracy can be diminished by phase aberrations resulting from substrate misalignment in fabrication. To address this, we introduce index-matched two-photon polymerization (IM-TPP) for fabricating DNNs. Numerical [...] Read more.
Two-photon polymerization (TPP) is an effective and rapid method for prototyping diffractive neural networks (DNNs). However, DNNs’ accuracy can be diminished by phase aberrations resulting from substrate misalignment in fabrication. To address this, we introduce index-matched two-photon polymerization (IM-TPP) for fabricating DNNs. Numerical simulations show that DNNs’ accuracy on tilted substrates improved from 91.50% to 95.00%. Experimentally, the IM-TPP process enhances device accuracy by 3.00% (91.67% to 94.67%), closely matching the theoretical simulated accuracy of 95.03%. Additionally, the average accuracy of multiple batches of samples reached 94.86%. IM-TPP reduces the influence of tilt error, improves device performance and manufacturing repeatability, and provides a new method for rapid prototyping of high-precision optical computing elements. Full article
(This article belongs to the Special Issue Advanced Optics and Photonics: Additive Manufacturing)
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46 pages, 25492 KiB  
Review
Recent Advancement in Fluorescent Probes for Peroxynitrite (ONOO)
by Hai-Hao Han, Pan-Xin Ge, Wen-Jia Li, Xi-Le Hu and Xiao-Peng He
Sensors 2025, 25(10), 3018; https://doi.org/10.3390/s25103018 - 10 May 2025
Viewed by 734
Abstract
Peroxynitrite (ONOO) is a reactive nitrogen species (RNS) that plays pivotal roles in various physiological and pathological processes. The recent literature has seen significant progress in the development of highly sensitive and selective fluorescent probes applicable for monitoring ONOO dynamics [...] Read more.
Peroxynitrite (ONOO) is a reactive nitrogen species (RNS) that plays pivotal roles in various physiological and pathological processes. The recent literature has seen significant progress in the development of highly sensitive and selective fluorescent probes applicable for monitoring ONOO dynamics in live cells and a variety of animal models of human diseases. However, the clinical applications of those probes remain much less explored. This review delves into the biological roles of ONOO and summarizes the design strategies, sensing mechanisms, and bioimaging applications of near-infrared (NIR), long-wavelength, two-photon, and ratiometric fluorescent probes modified with a diverse range of functional groups responsive to ONOO. Furthermore, we will discuss the remaining problems that prevent the currently developed ONOO probes from translating into clinical practice. Full article
(This article belongs to the Special Issue Fluorescence Sensors for Biological and Medical Applications)
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27 pages, 452 KiB  
Article
Quantum Electrodynamics from Quantum Cellular Automata, and the Tension Between Symmetry, Locality, and Positive Energy
by Todd A. Brun and Leonard Mlodinow
Entropy 2025, 27(5), 492; https://doi.org/10.3390/e27050492 - 1 May 2025
Viewed by 607
Abstract
Recent work has demonstrated a correspondence that bridges quantum information processing and high-energy physics: discrete quantum cellular automata (QCA) can, in the continuum limit, reproduce quantum field theories (QFTs). This QCA/QFT correspondence raises fundamental questions about how matter/energy, information, and the nature of [...] Read more.
Recent work has demonstrated a correspondence that bridges quantum information processing and high-energy physics: discrete quantum cellular automata (QCA) can, in the continuum limit, reproduce quantum field theories (QFTs). This QCA/QFT correspondence raises fundamental questions about how matter/energy, information, and the nature of spacetime are related. Here, we show that free QED is equivalent to the continuous-space-and-time limit of Fermi and Bose QCA theories on the cubic lattice derived from quantum random walks satisfying simple symmetry and unitarity conditions. In doing so, we define the Fermi and Bose theories in a unified manner using the usual fermion internal space and a boson internal space that is six-dimensional. We show that the reduction to a two-dimensional boson internal space (two helicity states arising from spin-1 plus the photon transversality condition) comes from restricting the QCA theory to positive energies. We briefly examine common symmetries of QCAs and how time-reversal symmetry demands the existence of negative-energy solutions. These solutions produce a tension in coupling the Fermi and Bose theories, in which the strong locality of QCAs seems to require a non-zero amplitude to produce negative-energy states, leading to an unphysical cascade of negative-energy particles. However, we show in a 1D model that, by extending interactions over a larger (but finite) range, it is possible to exponentially suppress the production of negative-energy particles to the point where they can be neglected. Full article
(This article belongs to the Special Issue Recent Advances and Challenges in Quantum Cellular Automata)
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