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Article

15 Citations

6,769 Views

9 Pages

Structure-Activity Relationships of the Bioactive Thiazinoquinone Marine Natural Products Thiaplidiaquinones A and B

Jacquie L. Harper,
Iman M. Khalil,
Lisa Shaw,
Marie-Lise Bourguet-Kondracki,
Joëlle Dubois,
Alexis Valentin,
David Barker and
Brent R. Copp

Mar. Drugs2015, 13(8), 5102-5110;https://doi.org/10.3390/md13085102

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10 August 2015

In an effort to more accurately define the mechanism of cell death and to establish structure-activity relationship requirements for the marine meroterpenoid alkaloids thiaplidiaquinones A and B, we have evaluated not only the natural products but al...

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Review

24 Citations

10,671 Views

26 Pages

Quinone and Hydroquinone Metabolites from the Ascidians of the Genus Aplidium

Camila Spereta Bertanha,
Ana Helena Januário,
Tavane Aparecida Alvarenga,
Letícia Pereira Pimenta,
Márcio Luis Andrade e Silva,
Wilson Roberto Cunha and
Patrícia Mendonça Pauletti

Mar. Drugs2014, 12(6), 3608-3633;https://doi.org/10.3390/md12063608

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12 June 2014

Ascidians of the genus Aplidium are recognized as an important source of chemical diversity and bioactive natural products. Among the compounds produced by this genus are non-nitrogenous metabolites, mainly prenylated quinones and hydroquinones. This...

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