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  • Article
  • Open Access
10 Citations
3,696 Views
10 Pages

Identification and Characterization of “Candidatus Rickettsia Thierseensis”, a Novel Spotted Fever Group Rickettsia Species Detected in Austria

  • Anna-Margarita Schötta,
  • Michiel Wijnveld,
  • Dieter Höss,
  • Gerold Stanek and ,
  • Hannes Stockinger and
  • Mateusz Markowicz
  • + 1 author+ 0 author

Rickettsia spp. are the second most common pathogens detected in Ixodes ricinus ticks in Austria after Borrelia burgdorferi sensu lato. Species belonging to the spotted fever group (SFG) are the causative agents for tick-borne rickettsiosis across th...

(This article belongs to the Special Issue Advance in Tick-Borne Diseases Research)
  • Article
  • Open Access
10 Citations
3,570 Views
8 Pages

Anaplasma phagocytophilum and Rickettsia spp. are tick-borne bacteria of veterinary and human concern. In view of the One-Health concept, the present study wanted to evaluate the spreading of these pathogens in horses living in central Italy. In part...

(This article belongs to the Special Issue Zoonotic Diseases and One Health)
  • Article
  • Open Access
13 Citations
4,286 Views
18 Pages

Co-Occurrence of Francisella, Spotted Fever Group Rickettsia, and Midichloria in Avian-Associated Hyalomma rufipes

  • Tove Hoffman,
  • Andreas Sjödin,
  • Caroline Öhrman,
  • Linda Karlsson and ,
  • Ryelan Francis McDonough,
  • Jason W. Sahl,
  • Dawn Birdsell,
  • David M. Wagner,
  • Laura G. Carra and
  • Björn Olsen
  • + 19 authors+ 14 authors

The migratory behavior of wild birds contributes to the geographical spread of ticks and their microorganisms. In this study, we aimed to investigate the dispersal and co-occurrence of Francisella and spotted fever group Rickettsia (SFGR) in ticks in...

(This article belongs to the Special Issue Research on Ticks and Tick-Borne Pathogens)
  • Article
  • Open Access
842 Views
10 Pages

Rickettsia parkeri as a Probable Agent of Mild Spotted-Fever Group Rickettsiosis Identified by Seroreactivity in Villeta, Colombia

  • Carlos Ramiro Silva-Ramos,
  • Peter C. Melby,
  • Patricia V. Aguilar,
  • Miguel M. Cabada and ,
  • Juan David Rodas,
  • Marylin Hidalgo and
  • Álvaro A. Faccini-Martínez
  • + 2 authors+ 0 author

Spotted fever group (SFG) rickettsioses are emerging zoonotic diseases of increasing relevance in Latin America, yet the specific species involved in human infections remain poorly defined in many endemic regions. This study aimed to determine the mo...

(This article belongs to the Special Issue Latin American Tropical Diseases: Epidemiology & Prevention)
  • Review
  • Open Access
12 Citations
5,667 Views
13 Pages

Spotted Fever Group Rickettsia spp. Molecular and Serological Evidence among Colombian Vectors and Animal Hosts: A Historical Review

  • Lídia Gual-Gonzalez,
  • Myriam E. Torres,
  • Stella C. W. Self,
  • Omar Cantillo-Barraza and
  • Melissa S. Nolan

2 March 2024

Spotted fever group Rickettsia spp. (SFGR) are a large group of tick-borne bacteria causing important emerging and re-emerging diseases that affect animals and humans. While SFGR are found worldwide, a lack of surveillance and misdiagnosis particular...

(This article belongs to the Topic Ticks and Tick-Borne Pathogens)
  • Article
  • Open Access
647 Views
16 Pages

Prevalence and Species Diversity of Spotted Fever Group Rickettsiae in Ixodid Ticks Collected in Northwest Russia

  • Islam Karmokov,
  • Olga Freylikhman,
  • Regina Baimova,
  • Daria Grechishkina and ,
  • Gelena Lunina,
  • Ivan Lyzenko,
  • Ekaterina Riabiko,
  • Tatiana Arbuzova,
  • Anastasiia Bachevskaia and
  • Nikolay Tokarevich
  • + 22 authors+ 17 authors

Rickettsia spp. are ubiquitous in nature and capable of causing diseases of varying severity. The most extensive group comprises the spotted fever group (SFG) Rickettsiae, the members of which are predominantly transmitted by ticks. The expansion of...

(This article belongs to the Special Issue The Distribution and Diversity of Tick-Borne Zoonotic Pathogens)
  • Article
  • Open Access
4 Citations
3,085 Views
13 Pages

The Rickettsia species transmitted by ticks are mostly classified within the spotted fever group rickettsiae (SFGR), which causes tick-borne rickettsiosis. Although efforts have been made to investigate their prevalence in the Republic of Korea (ROK)...

(This article belongs to the Topic Ticks and Tick-Borne Pathogens)
  • Article
  • Open Access
6 Citations
3,607 Views
14 Pages

Seroepidemiological Study of Spotted Fever Group Rickettsiae and Identification of a Putative New Species, Rickesttsia sp. Da-1, in Gongliao, Northeast Taiwan

  • Tsai-Ying Yen,
  • Hsi-Chieh Wang,
  • Yin-Chao Chang,
  • Chien-Ling Su and ,
  • Shu-Fen Chang,
  • Pei-Yun Shu and
  • Kun-Hsien Tsai
  • + 2 authors+ 0 author

4 November 2021

Tick-borne spotted fever group (SFG) rickettsioses were neglected in Taiwan. The study reported a seroepidemiological survey of SFG rickettsiae in residents in Gongliao District, Northeast Taiwan. Blood samples were examined for antibodies against SF...

(This article belongs to the Collection Updates on Rickettsia and Coxiella)
  • Article
  • Open Access
1,174 Views
12 Pages

Molecular Detection of Rickettsia spp. and Spotted Fever Group (SFG) Rickettsia in Arthropod Vectors from Northwestern Mexico

  • Sergio Luis Valle-Sánchez,
  • Roberto Rodríguez-Ramírez,
  • Luz Angélica Ávila-Villa,
  • Alma Guadalupe Villa-Lerma and ,
  • Blanca Areli Mondaca-Navarro,
  • Ramón Miguel Molina-Barrios and
  • Víctor García-González
  • + 2 authors+ 0 author

14 July 2026

Background: Rickettsioses are emerging diseases worldwide caused by intracellular bacteria of the genus Rickettsia. In recent years, these diseases have caused deaths in northwestern Mexico, particularly cases of Rocky Mountain spotted fever (RMSF)....

(This article belongs to the Section Infectious Disease Epidemiology, Prevention and Control)
  • Article
  • Open Access
18 Citations
6,306 Views
13 Pages

Development of a Multiplex Loop-Mediated Isothermal Amplification (LAMP) Method for Simultaneous Detection of Spotted Fever Group Rickettsiae and Malaria Parasites by Dipstick DNA Chromatography

  • Lavel Chinyama Moonga,
  • Kyoko Hayashida,
  • Naoko Kawai,
  • Ryo Nakao and ,
  • Chihiro Sugimoto,
  • Boniface Namangala and
  • Junya Yamagishi
  • + 2 authors+ 0 author

2 November 2020

Spotted fever group (SFG) rickettsiae causes febrile illness in humans worldwide. Since SFG rickettsiosis’s clinical presentation is nonspecific, it is frequently misdiagnosed as other febrile diseases, especially malaria, and complicates prope...

(This article belongs to the Special Issue Trends in Multiplex and Smart Technologies for In Vitro Diagnostics and Point-of-Care Testing)
  • Communication
  • Open Access
6 Citations
6,837 Views
5 Pages

New Foci of Spotted Fever Group Rickettsiae Including Rickettsia honei in Western Australia

  • Edward Raby,
  • Toby Pearn,
  • Andreas G. Marangou,
  • Adam J. Merritt and ,
  • Ronan J. Murray,
  • John R. Dyer and
  • Stephen R. Graves
  • + 2 authors+ 0 author

We describe the first reported case of spotted fever group rickettsiosis in Western Australia, and two cases of probable Rickettsia honei from a new geographic focus. These findings highlight the need to raise awareness of ricksettsial infection amon...

  • Brief Report
  • Open Access
8 Citations
3,210 Views
9 Pages

Human Spotted Fever Group Rickettsia Infecting Yaks (Bos grunniens) in the Qinghai-Tibetan Plateau Area

  • Yingna Jian,
  • Jixu Li,
  • Paul Franck Adjou Moumouni,
  • Xueyong Zhang and ,
  • Maria Agnes Tumwebaze,
  • Geping Wang,
  • Qigang Cai,
  • Xiuping Li,
  • Guanghua Wang and
  • Xuenan Xuan
  • + 8 authors+ 3 authors

The Qinghai-Tibetan Plateau Area (QTPA) is a plateau with the highest average altitude, located in Northwestern China. There is a risk for interspecies disease transmission, such as spotted fever rickettsioses. However, information on the molecular c...

(This article belongs to the Section Human Pathogens)
  • Article
  • Open Access
9 Citations
3,707 Views
8 Pages

New Spotted Fever Group Rickettsia Isolate, Identified by Sequence Analysis of Conserved Genomic Regions

  • Dar Klein,
  • Adi Beth-Din,
  • Regev Cohen,
  • Shirley Lazar and ,
  • Itai Glinert,
  • Hiba Zayyad and
  • Yafit Atiya-Nasagi
  • + 2 authors+ 0 author

20 December 2019

The clinical features of spotted fever group (SFG) Rickettsia induced disease range from a mild to severe illness. The clinical complexity is even greater due to the fact that the disease can be caused by different species with varying degrees of vir...

(This article belongs to the Section Human Pathogens)
  • Article
  • Open Access
5 Citations
4,046 Views
9 Pages

Beyond the IFA: Revisiting the ELISA as a More Sensitive, Objective, and Quantitative Evaluation of Spotted Fever Group Rickettsia Exposure

  • Navatha Alugubelly,
  • John V. Stokes,
  • Claire E. Cross,
  • Anne-Marie L. Ross and ,
  • Anna E. Crawford,
  • Gabrielle F. Fiihr and
  • Andrea S. Varela-Stokes
  • + 2 authors+ 0 author

20 January 2021

Based on limited serological studies, at least 10% of the US population has been exposed to spotted fever group Rickettsia (SFGR) species. The immunofluorescence antibody assay (IFA) has been the gold standard for the serodiagnosis of rickettsial inf...

(This article belongs to the Collection Updates on Rickettsia and Coxiella)
  • Feature Paper
  • Article
  • Open Access
10 Citations
3,125 Views
9 Pages

Prevalence of Spotted Fever Group Rickettsia and Candidatus Lariskella in Multiple Tick Species from Guizhou Province, China

  • Miao Lu,
  • Chao Meng,
  • Bing Zhang,
  • Xiao Wang and ,
  • Junhua Tian,
  • Guangpeng Tang,
  • Wen Wang,
  • Na Li,
  • Mengyao Li and
  • Kun Li
  • + 9 authors+ 4 authors

17 November 2022

Rickettsiales (Rickettsia spp., Ehrlichia spp., and Anaplasma spp., etc.) are generally recognized as potentially emerging tick-borne pathogens. However, some bacteria and areas in China remain uninvestigated. In this study, we collected 113 ticks fr...

(This article belongs to the Special Issue New Insight into Vector Borne Diseases)
  • Article
  • Open Access
11 Citations
2,946 Views
25 Pages

Diversity and Phylogeny of Cattle Ixodid Ticks and Associated Spotted Fever Group Rickettsia spp. in Tunisia

  • Myriam Kratou,
  • Hanene Belkahia,
  • Rachid Selmi,
  • Rihab Andolsi and ,
  • Mokhtar Dhibi,
  • Moez Mhadhbi,
  • Lilia Messadi and
  • Mourad Ben Said
  • + 3 authors+ 0 author

Tick-borne rickettsioses are mainly caused by obligate intracellular bacteria belonging to the spotted fever group (SFG) of the Rickettsia genus. So far, the causative agents of SFG rickettsioses have not been detected in cattle ticks from Tunisia. T...

(This article belongs to the Section Bacterial Pathogens)
  • Article
  • Open Access
2 Citations
1,805 Views
10 Pages

Differential Exposure to Borrelia spp. and Spotted Fever Group Rickettsia in Serbia and North Macedonia: A Comparative Study

  • Dejan Jakimovski,
  • Sofija Mateska,
  • Marija Najdovska,
  • Angela Stamenkovska and ,
  • Verica Pavleva,
  • Mile Bosilkovski,
  • Dragana Mijatović,
  • Verica Simin,
  • Ivana Bogdan and
  • Pavle Banović
  • + 11 authors+ 6 authors

17 August 2025

Several diseases caused by tick-borne pathogens, including Lyme borreliosis (LB) and spotted fever group rickettsioses, are endemic in the Balkan Peninsula, positioned between Central Europe and the Middle East. This cross-sectional study aimed to as...

(This article belongs to the Section Ticks)
  • Article
  • Open Access
11 Citations
4,235 Views
9 Pages

Molecular Evidence of Novel Spotted Fever Group Rickettsia Species in Amblyomma albolimbatum Ticks from the Shingleback Skink (Tiliqua rugosa) in Southern Western Australia

  • Mythili Tadepalli,
  • Gemma Vincent,
  • Sze Fui Hii,
  • Simon Watharow and ,
  • Stephen Graves and
  • John Stenos
  • + 1 author+ 0 author

Tick-borne infectious diseases caused by obligate intracellular bacteria of the genus Rickettsia are a growing global problem to human and animal health. Surveillance of these pathogens at the wildlife interface is critical to informing public health...

(This article belongs to the Collection Updates on Rickettsia and Coxiella)
  • Article
  • Open Access
16 Citations
6,252 Views
17 Pages

Background: Ticks transmit a plethora of pathogens of zoonotic implications. Their distribution, diversity and the pathogens they transmit differ from one ecological location to another. Rickettsia africae is the agent of African tick bite fever foun...

  • Article
  • Open Access
1,456 Views
12 Pages

Development and Evaluation of a Dual-Target One-Step Nested PCR for the Detection of Spotted Fever Group Rickettsia spp. in Ticks

  • Phiaw Chong Foo,
  • Canedy Jacob,
  • Christina Injan Mawang,
  • Ernieenor Faraliana Che Lah and
  • Mariana Ahamad

Spotted fever group (SFG) rickettsioses are tick-borne infectious diseases caused by more than 30 Rickettsia species. As ticks may harbor and transmit multiple pathogens during a single blood meal, sensitive and specific molecular detection methods a...

(This article belongs to the Special Issue Ticks and Tick-Borne Diseases in Southeast Asia)
  • Article
  • Open Access
5 Citations
3,001 Views
11 Pages

The Diversity of Spotted Fever Group Rickettsia Found in Ixodidae Hard Ticks Removed from Humans in Karachay-Cherkessia, North Caucasus, Russia

  • Alexey V. Rakov,
  • Tatiana A. Chekanova,
  • Ketevan Petremgvdlishvili,
  • Svetlana B. Linnik and ,
  • Khusey Kh. Batchaev and
  • Vasiliy G. Akimkin
  • + 1 author+ 0 author

Karachay-Cherkessia is the region in the Russian Federation that has been overlooked in terms of research on the human bacterial pathogens transmitted by ticks. In this study, we investigated the infection status of ticks with Rickettsia, Borrelia, C...

(This article belongs to the Special Issue One Health Research on Zoonotic Tick-Borne Pathogens)
  • Communication
  • Open Access
8 Citations
2,834 Views
9 Pages

High Prevalence of Rickettsia raoultii Found in Dermacentor Ticks Collected in Barnaul, Altai Krai, Western Siberia

  • Alexey V. Rakov,
  • Tatiana A. Chekanova,
  • Ketevan Petremgvdlishvili,
  • Andrey V. Timonin and ,
  • Anna V. Valdokhina,
  • Sergey V. Shirokostup,
  • Natalia V. Lukyanenko and
  • Vasiliy G. Akimkin
  • + 3 authors+ 0 author

The prevalence of the tick-borne spotted fever group rickettsioses pathogens in ticks collected in Barnaul, the administrative center of Altai Krai, Western Siberia, was studied. The causative agent of tick-borne lymphadenopathy (TIBOLA) Rickettsia r...

(This article belongs to the Special Issue Advances in Spotted Fever)
  • Article
  • Open Access
10 Citations
3,564 Views
12 Pages

Molecular Evidence of Rickettsia conorii subsp. raoultii and Rickettsia felis in Haemaphysalis intermedia Ticks in Sirumalai, Eastern Ghats, Tamil Nadu, South India

  • Krishnamoorthy Nallan,
  • Veerapathiran Ayyavu,
  • Elango Ayyanar,
  • Balaji Thirupathi and ,
  • Bhavna Gupta,
  • Panneer Devaraju,
  • Ashwani Kumar and
  • Paramasivan Rajaiah
  • + 3 authors+ 0 author

Rickettsia is an important pathogenic entity among tick-borne diseases (TBD), which are considered serious emerging public health problems globally. In India, though the widespread distribution of ticks and TBD has been documented, its real burden re...

(This article belongs to the Special Issue Emerging Research on Tick-Borne Pathogens and Diseases)
  • Article
  • Open Access
5 Citations
3,133 Views
11 Pages

Molecular Prevalence of Selected Tick-Borne Pathogens in Dermacentor reticulatus Collected in a Natural Park in Italy

  • Luca Villa,
  • Sergio Aurelio Zanzani,
  • Michele Mortarino,
  • Alessia Libera Gazzonis and ,
  • Emanuela Olivieri and
  • Maria Teresa Manfredi
  • + 1 author+ 0 author

Dermacentor reticulatus is one of the most important vectors of tick-borne pathogens (TBPs) in Europe causing diseases in animals and humans. A longitudinal study was planned, aimed to detect the molecular prevalence of tick-borne pathogens, i.e., Ba...

(This article belongs to the Special Issue Lyme Borreliosis and tick-borne infections)
  • Review
  • Open Access
11 Citations
4,302 Views
10 Pages

Spotted Fever Group Rickettsioses in Central America: The Research and Public Health Disparity among Socioeconomic Lines

  • Kyndall C. Dye-Braumuller,
  • Marvin S. Rodríguez Aquino,
  • Stella C. W. Self,
  • Mufaro Kanyangarara and
  • Melissa S. Nolan

27 July 2022

Tick-borne diseases including rickettsial diseases are increasing in incidence worldwide. Many rickettsial pathogens can cause disease which is commonly underdiagnosed and underreported; Rickettsia pathogens in the spotted fever group (SFGR) are thus...

(This article belongs to the Special Issue Insect Vector-Focused Approaches for Disease Control)
  • Case Report
  • Open Access
2 Citations
2,124 Views
8 Pages

Introduction: Spotted fever group (SFG) rickettsioses are tick-transmitted infections caused by Gram-negative, obligately intracellular bacteria in the genus Rickettsia. They present as an acute undifferentiated febrile illness, and they are often ac...

(This article belongs to the Section Bacterial Diseases)
  • Review
  • Open Access
12 Citations
6,859 Views
19 Pages

The Re-Emergence and Emergence of Vector-Borne Rickettsioses in Taiwan

  • Nicholas T. Minahan,
  • Chien-Chung Chao and
  • Kun-Hsien Tsai

Rickettsial diseases, particularly vector-borne rickettsioses (VBR), have a long history in Taiwan, with studies on scrub typhus and murine typhus dating back over a century. The climatic and geographic diversity of Taiwan’s main island and its offsh...

(This article belongs to the Special Issue The Past and Present Threat of Rickettsial Diseases)
  • Article
  • Open Access
3 Citations
1,272 Views
9 Pages

Molecular Detection of SFGR in Ticks Collected from Yaks in Jiulong County of Sichuan Province, China

  • Lili Hao,
  • Liangquan Zhu,
  • Chendong Xiao,
  • Rihong Jike and ,
  • Kelei Zhou,
  • Yinglin Li,
  • Quwu Jise,
  • Chang Wang and
  • Lu Deng
  • + 4 authors+ 0 author

28 March 2025

This study investigated tick species and spotted fever group rickettsiae (SFGR) infection rates in ticks from yaks in Jiulong County, Sichuan Province, China. Firstly, ticks collected from yaks were meticulously classified through morphological ident...

(This article belongs to the Special Issue Second Edition of Veterinary Parasitology: Epidemiology, Control and Prevention Strategies)
  • Article
  • Open Access
20 Citations
4,896 Views
14 Pages

Spotted Fever Group Rickettsia spp. Diversity in Ticks and the First Report of Rickettsia hoogstraalii in Romania

  • Talida Ivan,
  • Ioana Adriana Matei,
  • Cristiana Ștefania Novac,
  • Zsuzsa Kalmár and ,
  • Silvia-Diana Borșan,
  • Luciana-Cătălina Panait,
  • Călin Mircea Gherman,
  • Angela Monica Ionică,
  • Ionel Papuc and
  • Andrei Daniel Mihalca
  • + 5 authors+ 0 author

Tickborne bacterial pathogens have been described worldwide as risk factors for both animal and human health. Spotted fevers caused by Rickettsiae may cause non-specific symptoms, which make clinical diagnosis difficult. The aim of the current study...

(This article belongs to the Section Veterinary Food Safety and Zoonosis)
  • Article
  • Open Access
2 Citations
2,047 Views
10 Pages

Development of a Multiplex Droplet Digital PCR Assay for Detection of Tick-Borne Pathogens

  • Lijuan He,
  • Lin Zhang,
  • Like Duan,
  • Xuexia Hou and ,
  • Jingwen Li and
  • Qin Hao
  • + 1 author+ 0 author

13 February 2026

Tick-borne pathogens pose a significant threat to human health. In this study, a multiple droplet digital PCR (ddPCR) assay was developed to detect four tick-borne pathogens: Borrelia burgdorferi sensu lato (Bbsl), Coxiella burnetii (C. burnetii), sp...

  • Article
  • Open Access
17 Citations
4,258 Views
11 Pages

One Health Approach to Rickettsiosis: A Five-Year Study on Spotted Fever Group Rickettsiae in Ticks Collected from Humans, Animals and Environment

  • Ilaria Pascucci,
  • Elisa Antognini,
  • Cristina Canonico,
  • Marco Giuseppe Montalbano and ,
  • Alessandro Necci,
  • Alessandra di Donato,
  • Martina Moriconi,
  • Benedetto Morandi,
  • Giulia Morganti and
  • Stefano Gavaudan
  • + 6 authors+ 1 author

The spotted fever group of Rickettsiae is a heterogeneous group of Rickettsiae transmitted by ticks, causing similar diseases in humans (spotted fever). Until recently, it was supposed that a single pathogenic tick-borne SFG Rickettsia circulated in...

(This article belongs to the Special Issue Advances in Tick-Borne Diseases Research)
  • Article
  • Open Access
1 Citations
3,824 Views
18 Pages

Serological Evidence of Exposure to Spotted Fever Group and Typhus Group Rickettsiae in Australian Wildlife Rehabilitators

  • Karen O. Mathews,
  • David Phalen,
  • Jacqueline M. Norris,
  • John Stenos and ,
  • Jenny-Ann Toribio,
  • Nicholas Wood,
  • Stephen Graves,
  • Paul A. Sheehy,
  • Chelsea Nguyen and
  • Katrina L. Bosward
  • + 5 authors+ 0 author

Rickettsioses are arthropod-borne zoonotic diseases, several of which occur in Australia. This study aimed to assess the exposure levels and risk factors for Rickettsia spp. among Australian wildlife rehabilitators (AWRs) using serology, PCR and a qu...

(This article belongs to the Collection Updates on Rickettsia and Coxiella)
  • Article
  • Open Access
19 Citations
3,674 Views
18 Pages

Spotted Fever Group Rickettsiae in Ticks and Small Mammals from Grassland and Forest Habitats in Central Germany

  • Charlotte Arz,
  • Nina Król,
  • Christian Imholt,
  • Kathrin Jeske and ,
  • Zaida Rentería-Solís,
  • Rainer G. Ulrich,
  • Jens Jacob,
  • Martin Pfeffer and
  • Anna Obiegala
  • + 4 authors+ 0 author

Rickettsiae of the spotted fever group (SFG) are zoonotic tick-borne pathogens. Small mammals are important hosts for the immature life stages of two of the most common tick species in Europe, Ixodes ricinus and Dermacentor reticulatus. These hosts a...

(This article belongs to the Section Ticks)
  • Article
  • Open Access
27 Citations
5,350 Views
18 Pages

Molecular Detection of Spotted-Fever Group Rickettsiae in Ticks Collected from Domestic and Wild Animals in Corsica, France

  • Vincent Cicculli,
  • Oscar Maestrini,
  • Francois Casabianca,
  • Natacha Villechenaud and ,
  • Remi Charrel,
  • Xavier de Lamballerie and
  • Alessandra Falchi
  • + 2 authors+ 0 author

4 September 2019

To obtain a better understanding of the current magnitude of tick-borne rickettsioses in Corsica, we used molecular methods to characterize the occurrence of Rickettsia spp. in ixodid ticks collected from domestic and wild animals. The presence of Ri...

(This article belongs to the Section Animal Pathogens)
  • Article
  • Open Access
12 Citations
3,073 Views
14 Pages

Tick Species Diversity and Molecular Identification of Spotted Fever Group Rickettsiae Collected from Migratory Birds Arriving from Africa

  • Elisa Mancuso,
  • Marco Di Domenico,
  • Luigina Di Gialleonardo,
  • Michela Menegon and ,
  • Luciano Toma,
  • Marco Di Luca,
  • Francesca Casale,
  • Guido Di Donato,
  • Laura D’Onofrio and
  • Federica Monaco
  • + 9 authors+ 4 authors

The role of migratory birds in the spread of ticks and tick-borne pathogens along their routes from Africa to Europe is increasingly emerging. Wild birds can host several tick species, often infected by bacteria responsible for zoonoses. The aim of t...

(This article belongs to the Special Issue Emerging Research on Tick-Borne Pathogens and Diseases)
  • Review
  • Open Access
29 Citations
5,063 Views
25 Pages

Identifying the species that act as hosts, vectors, and vehicles of vector-borne pathogens is vital for revealing the transmission cycles, dispersal mechanisms, and establishment of vector-borne pathogens in nature. Ticks are common vectors for patho...

(This article belongs to the Special Issue Ticks and Tick-Borne Diseases in Animals)
  • Review
  • Open Access
105 Citations
14,052 Views
11 Pages

13 October 2021

Rickettsia species causing human illness are present globally and can cause significant disease. Diagnosis and identification of this intracellular bacteria are challenging with many available diagnostic modalities suffering from several shortcomings...

(This article belongs to the Collection Updates on Rickettsia and Coxiella)
  • Article
  • Open Access
5 Citations
1,480 Views
12 Pages

High Diversity and Prevalence of Rickettsial Agents in Rhipicephalus microplus Ticks from Livestock in Karst Landscapes of Southwest China

  • Ya-Ting Liu,
  • Yi-Fei Wang,
  • Ming-Zhu Zhang,
  • Dai-Yun Zhu and ,
  • Yi Sun,
  • Cai-Wei Gong,
  • Lin Zhan,
  • Xiao-Ming Cui and
  • Wu-Chun Cao
  • + 4 authors+ 0 author

Ticks and tick-borne pathogens pose a significant threat to human and animal health, yet the diversity and prevalence of tick-borne microorganisms in karst regions remains inadequately explored. In October 2023, a total of 274 Rhipicephalus microplus...

(This article belongs to the Section Public Health Microbiology)
  • Article
  • Open Access
1 Citations
3,758 Views
17 Pages

Antibody Prevalence and Risk Factors Associated with Rickettsia spp. in a Pediatric Cohort: SFGR Remains Underdiagnosed and Underreported in El Salvador

  • Kyndall C. Dye-Braumuller,
  • Marvin Stanley Rodríguez Aquino,
  • Kia Zellars,
  • Hanna Waltz and ,
  • Madeleine Meyer,
  • Lídia Gual-Gonzalez,
  • Stella C. W. Self,
  • Mufaro Kanyangarara and
  • Melissa S. Nolan
  • + 4 authors+ 0 author

27 October 2022

Spotted fever group rickettsioses (SFGR) are caused by a group of tick-borne pathogens that are increasing in incidence globally. These diseases are typically underreported and undiagnosed in low- and middle-income countries, and thus, have been clas...

  • Review
  • Open Access
44 Citations
7,369 Views
24 Pages

Rickettsia amblyommatis in Ticks: A Review of Distribution, Pathogenicity, and Diversity

  • Elise A. Richardson,
  • R. Michael Roe,
  • Charles S. Apperson and
  • Loganathan Ponnusamy

Rickettsia amblyommatis is a potentially pathogenic species of Rickettsia within the spotted fever group vectored by ticks. While many studies have been published on this species, there is debate over its pathogenicity and the inhibitory role it play...

(This article belongs to the Special Issue Emerging Research on Tick-Borne Pathogens and Diseases)
  • Article
  • Open Access
9 Citations
3,137 Views
11 Pages

Rickettsia spp. in Ticks of South Luangwa Valley, Eastern Province, Zambia

  • Bruno S. J. Phiri,
  • Simone Kattner,
  • Lidia Chitimia-Dobler,
  • Silke Woelfel and ,
  • Celina Albanus,
  • Gerhard Dobler and
  • Thomas Küpper
  • + 2 authors+ 0 author

Ticks are important vectors for Rickettsia spp. belonging to the Spotted Fever Group responsible for causing Rickettsiosis worldwide. Rickettsioses pose an underestimated health risk to tourists and local inhabitants. There is evidence of the presenc...

(This article belongs to the Section Parasitology)
  • Article
  • Open Access
22 Citations
6,665 Views
14 Pages

Significant Growth by Rickettsia Species within Human Macrophage-Like Cells Is a Phenotype Correlated with the Ability to Cause Disease in Mammals

  • M. Nathan Kristof,
  • Paige E. Allen,
  • Lane D. Yutzy,
  • Brandon Thibodaux and ,
  • Christopher D. Paddock and
  • Juan J. Martinez
  • + 1 author+ 0 author

19 February 2021

Rickettsia are significant sources of tick-borne diseases in humans worldwide. In North America, two species in the spotted fever group of Rickettsia have been conclusively associated with disease of humans: Rickettsia rickettsii, the causative agent...

(This article belongs to the Special Issue Virulence Mechanisms of Rickettsiae)
  • Review
  • Open Access
35 Citations
9,588 Views
13 Pages

Rickettsiae are an interesting group of bacteria comprising a large number of obligate intracellular species. The circulation of these bacteria in the environment depends on the presence of vectors (blood-sucking invertebrates) and their hosts. On th...

(This article belongs to the Topic Zoonotic Vector-Borne Diseases of Companion Animals)
  • Article
  • Open Access
15 Citations
4,804 Views
13 Pages

Detection of Rickettsia spp. in Animals and Ticks in Midwestern Brazil, Where Human Cases of Rickettsiosis Were Reported

  • Lucianne Cardoso Neves,
  • Warley Vieira de Freitas Paula,
  • Luiza Gabriella Ferreira de Paula,
  • Bianca Barbara Fonseca da Silva and ,
  • Sarah Alves Dias,
  • Brenda Gomes Pereira,
  • Bruno Sérgio Alves Silva,
  • Anaiá da Paixão Sevá,
  • Filipe Dantas-Torres and
  • Felipe da Silva Krawczak
  • + 6 authors+ 1 author

9 April 2023

Brazilian spotted fever (BSF) is the most important tick-borne diseases affecting humans in Brazil. Cases of BSF have recently been reported in the Goiás state, midwestern Brazil. All cases have been confirmed by reference laboratories by sero...

(This article belongs to the Topic Zoonotic Vector-Borne Diseases of Companion Animals)
  • Review
  • Open Access
18 Citations
5,534 Views
14 Pages

A Vaccine for Canine Rocky Mountain Spotted Fever: An Unmet One Health Need

  • David H. Walker,
  • Lucas S. Blanton,
  • Maureen Laroche,
  • Rong Fang and
  • Hema P. Narra

28 September 2022

Outbreaks of life-threatening Rocky Mountain spotted fever in humans and dogs associated with a canine-tick maintenance cycle constitute an important One Health opportunity. The reality of the problem has been observed strikingly in Mexico, Brazil, C...

(This article belongs to the Special Issue Immunity and Vaccination against Bacterial Infections)
  • Article
  • Open Access
22 Citations
5,619 Views
7 Pages

Ixodes holocyclus Tick-Transmitted Human Pathogens in North-Eastern New South Wales, Australia

  • Stephen R. Graves,
  • Chrissie Jackson,
  • Hazizul Hussain-Yusuf,
  • Gemma Vincent and ,
  • Chelsea Nguyen,
  • John Stenos and
  • Maurice Webster
  • + 2 authors+ 0 author

A group of 14 persons who live in an area of Australia endemic for the Australian paralysis tick, Ixodes holocyclus, and who were involved in regularly collecting and handling these ticks, was examined for antibodies to tick-transmitted bacterial pat...

  • Communication
  • Open Access
1 Citations
3,408 Views
9 Pages

Multiplex TaqMan® Quantitative PCR Assays for Host-Tick-Pathogen Studies Using the Guinea Pig-Tick-Rickettsia System

  • Anne-Marie L. Ross,
  • John V. Stokes,
  • Claire E. Cross,
  • Navatha Alugubelly and
  • Andrea S. Varela-Stokes

Spotted Fever Rickettsiosis (SFR) is caused by spotted fever group Rickettsia spp. (SFGR), and is associated with symptoms common to other illnesses, making it challenging to diagnose before detecting SFGR-specific antibodies. The guinea pig is a val...

(This article belongs to the Section Ticks)
  • Article
  • Open Access
14 Citations
4,419 Views
19 Pages

Rickettsia parkeri with a Genetically Disrupted Phage Integrase Gene Exhibits Attenuated Virulence and Induces Protective Immunity against Fatal Rickettsioses in Mice

  • Esteban Arroyave,
  • Ilirjana Hyseni,
  • Nicole Burkhardt,
  • Yong-Fang Kuo and ,
  • Tian Wang,
  • Ulrike Munderloh and
  • Rong Fang
  • + 2 authors+ 0 author

Although rickettsiae can cause life-threatening infections in humans worldwide, no licensed vaccine is currently available. To evaluate the suitability of live-attenuated vaccine candidates against rickettsioses, we generated a Rickettsia parkeri mut...

(This article belongs to the Special Issue Virulence Mechanisms of Rickettsiae)
  • Review
  • Open Access
18 Citations
8,314 Views
12 Pages

Tick-Borne Rickettsioses in the Iberian Peninsula

  • Leonardo Moerbeck,
  • Ana Domingos and
  • Sandra Antunes

18 November 2022

Tick-borne rickettsioses (TBR) are caused by obligate, intracellular bacteria of the spotted-fever group (SFG) of the genus Rickettsia (Order Rickettsiales), transmitted by hard ticks. TBR are one of the oldest known vector-borne zoonoses and pose a...

(This article belongs to the Special Issue Ticks and Tick-Borne Diseases―Pathogens, Parasites and People)
  • Communication
  • Open Access
5 Citations
3,822 Views
9 Pages

The Molecular Detection of Bacterial Infections of Public Health Importance in Hard Tick (Ixodidae) Nymphs Collected from the Forest Fringes of Western Ghats in the Goa, Karnataka and Maharashtra States of India

  • Gnanasekar Ragini,
  • Hari Kishan Raju,
  • Ranganathan Krishnamoorthi,
  • Ayyanar Elango and ,
  • Subramanian Muthukumaravel and
  • Ashwani Kumar
  • + 1 author+ 0 author

A survey was conducted to determine the human tick-borne bacterial infections in the nymphs which were collected from Western Ghats’ fringe forest areas. Tick nymphs were collected using the flagging method from the villages where cases Kyasanur Fore...

(This article belongs to the Special Issue Advanced Research on Ticks and Tick-Borne Diseases: 2nd Edition)

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