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Article

9 Citations

4,907 Views

24 Pages

Yuccalechins A–C from the Yucca schidigera Roezl ex Ortgies Bark: Elucidation of the Relative and Absolute Configurations of Three New Spirobiflavonoids and Their Cholinesterase Inhibitory Activities

Łukasz Pecio,
Mostafa Alilou,
Solomiia Kozachok,
Ilkay Erdogan Orhan,
Gokcen Eren,
Fatma Sezer Senol Deniz,
Hermann Stuppner and
Wiesław Oleszek

Molecules2019, 24(22), 4162;https://doi.org/10.3390/molecules24224162

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16 November 2019

The ethyl acetate fraction of the methanolic extract of Yucca schidigera Roezl ex Ortgies bark exhibited moderate acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activity (IC50 47.44 and 47.40 µg mL−1, respectively...

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Review

12 Citations

4,174 Views

42 Pages

Spiro-Flavonoids in Nature: A Critical Review of Structural Diversity and Bioactivity

Łukasz Pecio,
Solomiia Pecio,
Tomasz Mroczek and
Wiesław Oleszek

Molecules2023, 28(14), 5420;https://doi.org/10.3390/molecules28145420

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14 July 2023

Based on the literature data from 1973 to 2022, this work summarizes reports on spiro-flavonoids with a spiro-carbon at the center of their structure and how this affects their isolation methods, stereochemistry, and biological activity. The review c...

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