Search Results (5,122)

Urban areas are increasingly affected by geological and climate-driven processes that influence their safety, functionality, and long-term resilience. Conventional sustainability indicators mainly focus on anthropogenic impacts on the environment, while the role of subsurface conditions and physical processes shaping urban vulnerability remains underrepresented. To address this gap, the Urban Geo-climate Footprint (UGF) introduced an inverse perspective, assessing how geological and climatic factors exert pressure on urban systems. The methodology is based on the classification of geological effects into five drivers: Geology, Deep Geological Processes, Surface Processes, Exogenous and Climatic Processes, and Subsurface Anthropogenic Pressure. These drivers, within the proposed framework, are articulated into 22 parameters evaluated using public datasets and expert judgment. These parameters are combined into a synthetic, standardised, reproducible and comparable index, the UGF Score Index (UGF-SI), ranging from 0 to >500 which enables direct comparison across cities and contexts. The application to 21 Italian cities highlights distinct spatial patterns, dominant drivers, and groups of cities facing similar geo-climatic challenges. The UGF framework constitutes a significant advancement in urban geoscience, supporting urban planning, risk awareness, and climate adaptation strategies by enhancing the understanding of subsurface-related pressures and promoting informed decision making. Full article

Macroeconomic systems are increasingly characterized by fractal structures, entropy-generating processes, and chaotic dynamics that challenge the assumptions of traditional regression methods. The presence of self-similarity, fractal structure, and sensitivity to initial conditions suggests that macroeconomic variables evolve through complex interactions that cannot be adequately explained within an equilibrium-based method. Motivated by this perspective, this paper tested the relationships between oil prices and macroeconomic variables in the United States over the period of 1960–2024 using a suggested fractal regression approach. The analysis proceeds in two stages. In the first stage, fractal, entropy, and chaotic structures of the variables were analyzed by employing entropy measures, Lyapunov exponents, attractor diagnostics by including Lorenz and Julia structures, and tests for fractal dimension: d parameter (GPH) and d parameter (Phillips), and long range dependendeceLo’s Modified R/S, and Hurst–Mandelbrot R/S. Our results explored evidence of fractal structure, complexity, and chaotic behavior within the selected macroeconomic series by indicating the presence of nonlinear dynamics and sensitivity to initial conditions. In the second stage, a proposed chaotic–fractal-based regression model is employed to explore the transmission mechanism of oil price to economic growth, inflation, and unemployment. By directly incorporating Lyapunov and fractal-based measures into the regression method, the model captured nonlinear interactions that are overlooked by traditional methods. The results revealed that oil price shocks generate chaotic and fractal effects across macroeconomic variables and that these effects vary according to the degree of chaotic divergence embedded in the system. Overall, the results suggested the interconnected roles of fractality, entropy, and chaos in shaping macroeconomic dynamics and showed the importance of chaos- and fractal-based modeling methods for understanding the economic consequences of energy shocks and their policy implications. Full article

Introduction: We investigated the effect of transverse maxillary constriction on nasal septal deviation (NSD) and nasal floor slanting. Methods: 60 growing Wistar rats (21 days old) were divided into four groups: (1) Experimental Group 1 received active constriction force (100cN), (2) Experimental Group 2 received active expansion force (100cN), (3) Sham received the same spring as Experimental Groups without receiving any active force, and (4) Control group did not receive any appliance. Samples were collected after 28 days for microcomputed tomography (μCT) analysis. Results: Experimental Group 1 demonstrated maxillary constriction (both skeletal and dental), accompanied by mandibular shift on closure, clockwise mandibular rotation, and increased mandibular plane angle and facial height. Constriction was also associated with severe nasal floor slanting in the molar area that extended posteriorly. Nasal floor canting was accompanied by a slanted vomer and a C-shaped NSD. The direction of nasal floor canting and mandibular shift was always similar. Experimental Group 2, on the other hand, was not associated with nasal deviation, and a slight slanting of the nasal floor was observed only when there was a mandibular shift. Conclusions: Our study suggests that the constricting transverse forces applied to the maxilla can be associated with nasal septal deviation. One possible mechanism by which constriction contributes to nasal septal deviation is by promoting mandibular shift. Mandibular shift, in turn, dictates the direction of slanting of the nasal floor and, consequently, the vomer, which may, in turn, lead to nasal septal deviation. Full article

Age-associated metabolic dysfunction is commonly defined by abnormalities in adiposity, glucose regulation, lipid metabolism, and blood pressure. Although clinically useful, these criteria do not fully capture the biological heterogeneity that explains why older adults with similar metabolic profiles may follow divergent trajectories toward type 2 diabetes, cardiovascular disease, metabolic dysfunction-associated steatotic liver disease, frailty or multimorbidity. This narrative Review summarizes clinical, translational, and mechanistic evidence on the biological processes that shape metabolic aging, with particular emphasis on inflammaging, immunosenescence, cellular senescence, oxidative stress, mitochondrial dysfunction, adipose tissue dysfunction, endothelial injury, and inflammation-related microRNAs. We first discuss how chronic low-grade inflammation and immune remodeling alter the interpretation of conventional metabolic syndrome components in older adults. We then review redox imbalance and mitochondrial stress as amplifiers of insulin resistance, lipid injury, vascular dysfunction, and tissue remodeling. The review also examines inflammation-related microRNAs, including circulating and extracellular-vesicle-associated miRNAs, as post-transcriptional regulators that may connect inflammatory, metabolic, and redox pathways. Finally, we discuss how conventional metabolic markers may be integrated with inflammatory mediators, oxidative-stress indicators, adipokines, endothelial and senescence-related markers, and miRNA profiles to improve biological interpretation of metabolic risk. Within this context, we present the Inflammaging–Redox–InflammamiR Axis as a conceptual framework for organizing these overlapping mechanisms rather than as an established diagnostic or causal model. The proposed biomarker tiers and candidate risk phenotypes are author-derived, hypothesis-generating constructs intended to guide future longitudinal and interventional research. Clinical translation will require standardized assays, longitudinal validation, external replication, and intervention studies. Full article

Coastal communities that depend on marine resources face both chronic and acute threats from harmful algal blooms (HABs), requiring effective institutional responses. Resilience provides a useful framework for assessing how communities monitor, respond to, and adapt to these hazards and how institutions shape those capacities. Historically, communities have developed institutions to mitigate such risks, making institutional resilience a valuable analytical lens. This paper adopts a comparative perspective to examine institutional measures for preventing and mitigating HABs in coastal waters. It analyzes resilience-building measures in four democracies with distinct institutional configurations: the United States, Australia, Norway, and Japan. By distinguishing between ex ante (proactive) and ex post (reactive) measures and comparing responses to temporally similar HAB events, the analysis identifies institutions as key factors shaping risk assessment, monitoring adoption, and policy effectiveness. Evaluating HAB governance through a resilience lens provides a practical basis for planners and decision-makers to develop more balanced response portfolios. The findings suggest that sustained investment in proactive as well as reactive measures is key to strengthening long-term adaptive capacity in addressing HAB risks. Note: A list of abbreviations is provided before the References Section. Full article

The assessment of consciousness has been shaped largely by research on acquired disorders of consciousness after acute or chronic brain injury, but similar problems of unreliable behavioral expression increasingly arise in neurodegenerative disease. This translational overlap is especially relevant when preserved cognition, awareness, or intentionality cannot be reliably expressed because of severe motor impairment, fluctuating arousal, cognitive decline, aphasia, apraxia, or impaired cooperation. In neurodegenerative disease, degeneration of arousal systems, large-scale brain networks, cognition, and motor pathways may similarly make observable behavior an unreliable measure of awareness. The challenge is not only to determine if a patient responds, but also to ask if residual awareness, intentionality, or covert cognition can still be detected through physiological signals. This review discusses how contemporary modalities reshape this assessment. Electroencephalography has moved from a descriptive measure of background activity to a bedside tool capable of probing event-related responses, network organization, and cortical complexity. Magnetic resonance methods reveal altered connectivity within thalamocortical and default mode network systems, while functional near-infrared spectroscopy adds a portable hemodynamic approach that may be repeated at the bedside and integrated with active paradigms. Brain–computer interfaces provide a translational step by converting neural responses into evidence of command following or, in selected patients, into communication, and artificial intelligence strengthens these approaches by extracting clinically meaningful patterns from complex neural and hemodynamic data. Additionally, autonomic measures, including heart rate variability and baroreflex indices, are considered as auxiliary physiological context for arousal and engagement, and not as direct markers of awareness. Because the most mature evidence for covert awareness and cognitive-motor dissociation comes from acquired disorders of consciousness, this review treats brain injury literature as a methodological foundation instead of as directly interchangeable evidence for neurodegenerative disease. It then examines how these approaches may be adapted to neurodegenerative contexts, especially ALS, severe dementia, Lewy body disease with fluctuating cognition, and conditions in which communication or motor output becomes unreliable. Full article

Soil texture is a key determinant shaping bacterial communities in vineyard ecosystems, yet how different soil textures modulate bacterial characteristics in rhizosphere versus bulk soils during grapevine growth remains poorly understood. This study collected rhizosphere and bulk soil samples from five commercial Vitis vinifera cv. Cabernet Sauvignon vineyards in the eastern piedmont of Helan Mountain, Ningxia, China, spanning three distinct textures (gravelly, calcareous, and aeolian sandy soils). Shotgun metagenomic sequencing, soil physicochemical analysis, and four soil enzyme activity (alkaline phosphatase, urease, catalase, and invertase) measurements were conducted, using PERMANOVA and RDA to identify dominant driving factors. The results showed that bacteria accounted for 97.6% of all annotated sequences, representing the dominant group in soil microbial communities. Significant differences in bacterial abundance and alpha diversity (Chao1, ACE, Shannon, and Simpson) were observed in bulk soils across textures, whereas rhizosphere soils showed significant abundance differences but similar diversity levels. However, the 50 cm bulk soil sampling distance may have attenuated the true rhizosphere effect, and these findings should be interpreted with this methodological constraint in mind. Notably, bacterial community structure differed significantly between soils of the same pedogenic type but different textures, confirming that soil texture, rather than pedogenic classification, is the primary driver. Thirteen dominant bacterial phyla (>1% relative abundance) were identified, with Proteobacteria (47.7%), Actinobacteriota (22.9%), and Acidobacteriota (6.5%) as the main taxa. Mantel tests revealed significant correlations between nitrogen, phosphorus, organic matter contents and enzyme activities in rhizosphere soils (r ≥ 0.4, p < 0.01). RDA indicated that total phosphorus (TP), organic matter (OM), alkali-hydrolyzable nitrogen (AN), Mg, pH, available K (AK), and enzyme activities were key drivers of bacterial community structure (p < 0.05). Annotated metabolic functions based on KEGG orthology indicated lower overall metabolic pathway abundances in gravelly soils compared to calcareous and aeolian sandy soils. In conclusion, soil texture, rather than broad pedogenic classification, primarily shapes vineyard bacterial communities, providing a theoretical basis for precision viticulture and sustainable soil management. Full article

Commercial egg grading remains anchored to weight-based thresholds, a single metric that incompletely represents internal composition and is automated only through industrial graders too costly for small and medium-sized enterprises. Existing parametric egg models treat volume in isolation from grading and rely on parameters that are difficult to extract from simple measurements. We propose a two-parameter geometric framework adapting Smart’s parametric egg profile to the ISA Brown breed, in which the egg asymmetry is encoded through a single dimensionless shape parameter and the volume is obtained in closed form as a solid of revolution from only the maximum length and maximum width. The model is validated on 120 ISA Brown eggs against fluid-displacement ground truth, attaining a Pearson correlation of $0.894$ and a mean absolute percentage error of $6.02\%$; a single closed-form correction factor, derived from the model’s own $b^2$-dependence, reduces the error to $3.09\%$, below that of an empirically fitted formula. A closed-form linear discriminant on the same two measurements recovers the commercial grade with $92.0\%$ cross-validated accuracy, and the product $H·W^2$ alone classifies $93.3\%$ by a single arithmetic rule. The shape parameter and whole-egg density are essentially invariant across grades, establishing a geometric self-similarity that reduces the framework to breed-level constants. Full article

This article examines the comparative method in environmental law through a systematic bilateral analysis of the foundational environmental protection laws adopted in Ukraine in 1991 and in Lithuania in 1992. The overarching aim is to contribute to the underexplored field of Ukraine-Lithuania comparative research by identifying similarities and differences and situating them within post-Soviet legal development and European integration processes. The study adopts a mixed methodological design combining a scoping-oriented literature review, consisting of a targeted narrative review using Google Scholar and a systematic review in accordance with PRISMA 2020 guidelines using the Scopus database (n = 23), with a structured doctrinal comparison of the two legal acts. The literature review identifies four main rationales for comparing Ukraine and Lithuania in academic scholarship: shared Soviet historical heritage, post-socialist transition processes, cultural and societal similarities, and the identification of research gaps. The paper further demonstrates that comparative environmental law studies predominantly rely on broader post-Soviet or regional frameworks, with limited direct bilateral comparison between these two countries. The doctrinal analysis of environmental laws reveals both convergence and divergence. However, Lithuania exhibits a more dynamic and EU-integrated legislative trajectory characterised by continuous amendments and alignment with EU environmental acquis, whereas Ukraine demonstrates a more stable but less systematically EU-oriented legal evolution and comparatively gradual reform processes. The findings indicate that Europeanisation plays a key role in shaping divergent post-socialist environmental legal development. Lithuania represents a model of sustained EU-driven legal integration, while Ukraine reflects a more incremental adaptation path. The study contributes to the literature by providing a structured bilateral comparison of Ukraine and Lithuania in environmental law and by linking doctrinal differences to broader processes of post-Soviet transformation and Europeanisation. Full article

Designing consumer products with lower environmental impact and acceptable cost requires designers to interpret life-cycle evidence across competing alternatives. This study compares two contrasting weighting approaches for multi-criteria decision-making in sustainability-focused consumer product design: the stakeholder-preference-driven Analytic Hierarchy Process (AHP) and the data-driven Criteria Importance Through Intercriteria Correlation–Technique for Order of Preference by Similarity to Ideal Solution (CRITIC–TOPSIS) method. An electric-bike case study was constructed from 24 feasible configurations defined by frame material, battery type, tire material, and coating method. Environmental performance was quantified using Life Cycle Assessment (LCA) with ReCiPe midpoint indicators, and economic performance was represented using a component-level life-cycle cost proxy. The methods identified broadly similar high- and low-performing regions of the design space, but they differed in the ranking of specific alternatives. Statistical comparison showed strong agreement among the ranking methods, although differences remained in the exact ordering of some alternatives. These findings show that weighting methods do not determine product sustainability on their own; rather, they shape how environmental and economic evidence is translated into design decisions. For consumer product development, AHP is useful when stakeholder priorities must be made explicit, whereas CRITIC–TOPSIS is advantageous when repeatable data-driven screening is needed. Full article

Coral-associated microbial communities play a critical role in the health and resilience of reef ecosystems; however, the relative importance of host identity and environmental factors in shaping these communities remains unclear, particularly in understudied regions such as the Gulf of California. In this study, we characterized the taxonomic composition, diversity patterns, persistent taxa (core bacteriome), and predicted functional potential of bacterial communities associated with three coral genera (Pocillopora, Porites, and Pavona) and surrounding seawater using 16S rRNA gene amplicon sequencing and PICRUSt2-based functional inference. Bacterial community structure differed significantly among coral hosts (PERMANOVA, p < 0.01), whereas geographic location and measured physicochemical parameters had no detectable effect. Coral-associated bacterial communities exhibited lower alpha diversity than seawater and formed distinct host-specific clusters in beta-diversity analyses. Core bacteriome analysis revealed a combination of conserved and host-specific taxa, with Acinetobacter consistently present across hosts, while genera such as Pseudovibrio and Ruegeria showed host-specific associations. Differential abundance analyses further confirmed distinct bacterial signatures among coral genera. Predicted functional profiles were dominated by central metabolic pathways and exhibited significant differences among hosts, although overall functional composition remained relatively conserved. Stratified analyses indicated that similar metabolic pathways were supported by different taxonomic assemblages, suggesting functional redundancy. Overall, our results demonstrate that host identity is the primary driver of both taxonomic composition and predicted functional potential in coral-associated bacterial communities in the Gulf of California, highlighting the coexistence of stability and host-specific differentiation within the coral holobiont. Full article

This paper investigates how institutional fragilities shape cross-border cyber risk in financial systems, using the 2016 Bangladesh Bank heist as an illustrative case from a developing-country context. Drawing on a scoping review of the multidisciplinary literature on cybersecurity governance, financial cybercrime, and cross-border cyber risk, combined with an exploratory case study, the Bangladesh Bank heist is explored through a multi-level analytical lens encompassing macro-level institutional and geopolitical factors, meso-level ecosystem interdependencies, and micro-level organizational vulnerabilities. The analysis suggests that the 2016 heist was not solely a technical intrusion but was also associated with broader governance, regulatory, infrastructural, and organizational weaknesses. Fragmented governance arrangements, digital dependencies, limited operational resilience, inadequate cybersecurity controls, and human-factor vulnerabilities emerged as important dimensions of risk. Comparison with selected incidents from other developing and emerging economies indicates that similar patterns may occur across different institutional settings, although their manifestation remains context dependent. Rather than advancing a general theory, the highlights the importance of strengthening governance capacity, regulatory coordination, and cyber resilience within globally interconnected financial systems. Full article

The magnetic susceptibilities of various electrically insulating ordinary fluids depend on their local states, such as their density and temperature. When such fluids, which can be characterized as either paramagnetic or diamagnetic and occur commonly in nature, are subjected to magnetic field gradients, it induces an effective body force—the Kelvin force. This force, which depends on the susceptibility and the gradient of the square of the magnetic field strength, can become one of the effective mechanisms for modulating the flow and transport, particularly where terrestrial gravity becomes negligible, such as in free space or under microgravity conditions. For the first time, we developed a theoretical model demonstrating that a viscous current can be generated due to the contrasts between the magnetic susceptibilities of the intruding and ambient fluids in the presence of gradients in magnetic fields, analogous to the viscous gravity current in terrestrial situations. We derived similarity solutions for the two-dimensional and axisymmetric currents arising from a balance between the Kelvin buoyancy and viscous forces with a prescribed power law for the magnetic field strength. These determine the shape and various spreading relationships of the viscous current. For a prescribed time variation in the source flux, it is shown that a family of scaling laws exists for the spreading rate and the thickness of the current, which depend on the steepness of the magnetic field gradient. Unlike gravity, since the driving horizontal buoyancy arising from the Kelvin force is externally specified, it potentially offers a mechanism to control the characteristic shape and the rate of motion of the viscous current. Full article

This article discusses the relevant problem of ensuring transport connectivity under the conditions of temporal restrictions of the road network, which arise during repair, communal and emergency operations. It is established that the existing organizational and intellectual methods of traffic management do not eliminate physical decrease in road capacity, while construction of stationary structures with different levels is limited by high costs and long terms of implementation. The above substantiates the need for the development of mobile overpasses as adaptive engineering solutions ensuring continuity of the traffic flows. The purpose of the research is to develop a scientifically substantiated theoretical and experimental methodology for designing a mobile overpass as an integrated system “structure-moving load”, taking into account its dynamic behavior. The paper proposes an integrated approach based on the use of physical similarity theory and dimensionless analysis. A differential equation of dynamic bending of a beam on an elastic foundation is formulated taking into account inertia, damping, base reaction and the effect of a moving mass, and then its nondimensionalization is performed to obtain a similarity criteria system. The scientific novelty of the research consists in developing a system of dimensionless criteria to describe the relationship between the structural, dynamic and operational parameters of a mobile overpass, as well as in the formation of a criterion base for large-scale modeling and transfer of the results to full-scale structures. The proposed methodology describes the mobile overpass as an integrated transport-engineering system accounting for the coupled interaction between the deformable structure, moving traffic load, elastic foundation, and damping effects. Experimental verification was performed on a specially designed stand in the scale 1:4. The results obtained showed the quasi-static nature of the structure performance with moderate damping and rigid base. It is established that the distribution of engineering stresses along the span length has a regular character and retains its shape when the load level changes, which confirms fulfillment of similarity conditions. Regression analysis revealed a close to linear dependence of stresses on the load mass with a high degree of confidence $(R^2\approx 0.995)$. The practical significance of the research consists in creating an engineering method for express design of mobile overpasses, which allows for assessing their stress–strain state, stability and serviceability without expensive full-scale tests. The proposed approach can be used in designing temporary transportation structures under the conditions of urban area, and in operation in areas of road operations and emergency situations. Full article

Magnesium alloys are considered to be the third generation of biomaterials used in biomedical applications to promote bone tissue regeneration. Due to their Young’s modulus being similar to that of human bone and their release of magnesium ions that are antimicrobial and osteoinductive, these biomaterials not only promote bone regeneration, minimize the effects of stress shielding and reduce the risk of infection, but also their exceptional biocompatibility and bioresorbability eliminate the need for a second surgery to remove the implant. However, because magnesium has poor corrosion resistance, without different coatings and surface treatments, the implant can be compromised before the bone is fully healed. With additive manufacturing (AM) as a revolutionary technology, the one-size-fits-all approach can be replaced by fully personalized medicine, in which complex shapes can be created, designed, and processed with unique parameters for each patient. However, 3D printing of Mg-based devices remains particularly challenging due to magnesium’s high chemical reactivity, combustion risk, and low vaporization temperature, challenges that are further compounded when alloying elements are introduced. This review addresses this gap by critically examining the properties, corrosion behavior, and bio-medical performance of Mg and its alloys, with a focused analysis of selective laser melting (SLM) and wire arc additive manufacturing (WAAM) as key fabrication methods. The influence of processing parameters, microstructural defects, and alloy composition on the final properties of AM-fabricated Mg components is systematically discussed, alongside current limitations and prospective strategies toward their clinical translation. Full article