The Scribble polarity module is composed by Scribble (Scrib), Discs large 1 (Dlg1) and Lethal (2) giant larvae (L(2)gl), a group of highly conserved neoplastic tumor suppressor genes (TSGs) from flies to humans. Even though the Scribble module has be...
Scribble is a highly conserved regulator of cell polarity, a process that enables the generation of asymmetry at the cellular and tissue level in higher organisms. Scribble acts in concert with Disc-large (Dlg) and Lethal-2-giant larvae (Lgl) to form...
Canopy coverage is a key indicator for judging maize growth and production prediction during the seedling stage. Researchers usually use deep learning methods to estimate canopy coverage from maize images, but fully supervised models usually need pix...
The Scribble protein complex genes, consisting of lethal giant larvae (Lgl), discs large (Dlg) and scribble (Scrib) genes, are components of an evolutionarily conserved genetic pathway that links the cell polarity in cells of humans and Drosophila. T...
PDZ domains are involved in many cellular processes and are key regulators of the cell physiology. A huge number of studies have investigated the binding specificity of PDZ domains to the carboxyl-terminal sequence of target proteins, while the molec...
The role of LAP proteins expressed in skeletal muscles (ERBIN, LANO, and SCRIBBLE) and at neuromuscular junctions (NMJs) remains largely unknown. Our previous data demonstrate that LAP proteins are differentially expressed in muscle cells, nerve endi...
The transition in medical image segmentation from fine-grained to coarse-grained annotation methods, notably scribble annotation, offers a practical and efficient preparation for deep learning applications. However, these methods often compromise seg...
To address the issues of inadequate performance and excessive interaction costs when handling large-scale and complex-shaped change areas with existing interaction forms, this paper proposes RSICDNet, an interactive change detection (ICD) model with...
Social behavior is a basic domain affected by several neurodevelopmental disorders, including ASD and a heterogeneous set of neuropsychiatric disorders. The SCRIB gene that codes for the polarity protein SCRIBBLE has been identified as a risk gene fo...
A connection between compromised asymmetric cell division (ACD) and tumorigenesis was proven some years ago using Drosophila larval brain neural stem cells, called neuroblasts (NBs), as a model system. Since then, we have learned that compromised ACD...
The main characteristic of polycystic kidney disease is the development of multiple fluid-filled renal cysts. The discovery of mislocalized sodium-potassium pump (Na,K-ATPase) in the apical membrane of cyst-lining epithelia alluded to reversal of pol...
Crown segmentation is a pivotal process in the acquisition of tree parameters. In light of the high expenses associated with satellite remote sensing and LiDAR technologies, our study leverages the cost-effective and efficient UAV remote sensing tech...
Water is a vital component of life that exists in a variety of forms, including oceans, rivers, ponds, streams, and canals. The automated methods for detecting, segmenting, and mapping surface water have improved significantly with the advancements i...
This study analyses 749 drawings by five female Bornean orang-utans (Pongo pygmaeus) at Tama Zoological Park in Japan. We searched for differences between individuals but also tried to identify possible temporal changes among the drawings of one indi...
Human papillomavirus is the most common viral infectious agent responsible for cancer development in humans. High-risk strains are known to induce cancer through the expression of the viral oncogenes E6 and E7, yet we have only a partial understandin...
Cancer cachexia is a common deleterious paraneoplastic syndrome that represents an area of unmet clinical need, partly due to its poorly understood aetiology and complex multifactorial nature. We have interrogated multiple genetically defined larval...
Background: Treatment and outcomes of breast cancer, one of the most prevalent female cancers, have improved in recent decades. However, metastatic breast cancer remains incurable in most cases, and new therapies are needed to ameliorate prognosis. P...
Objectives: To analyse whether breastfeeding (BF) is related to better psychomotor development in the first two years of life. Methods: Prospective longitudinal study of a cohort of children born in Spain (between April 2017 and March 2018) and follo...
A novel approach for video instance segmentation is presented using semisupervised learning. Our Cluster2Former model leverages scribble-based annotations for training, significantly reducing the need for comprehensive pixel-level masks. We augment a...
This paper reviews the properties of the most cultivated species of the Moringaceae family, Moringa oleifera Lam. The paper takes a critical look at the positive and the associated negative properties of the plant, with particular emphasis on its che...
The acquisition of handwriting skills is a crucial goal in early primary school. Yet our comprehension of handwriting development, encompassing graphomotor skills and spelling, remains fragmented. The identification of predictors for handwriting skil...
The phenomenon of how oncogenes and tumor-suppressor mutations can synergize to promote tumor fitness and cancer progression can be studied in relatively simple animal model systems such as Drosophila melanogaster. Almost two decades after the landma...
Image matting refers to the task of estimating the foreground of images, which is an important problem in image processing. Recently, trimap generation has attracted considerable attention because designing a trimap for every image is labor-intensive...
The open studio art therapy model offers a space for free creation; in this space, the art therapist supports the participants’ art process. According to this model, the creative process is the central component of the therapeutic work. This qu...
Background/objectives: Early literacy is widely promoted, yet its broader developmental benefits remain underexamined regarding key indicators of brain development. This study examines whether early literacy exposure in toddlerhood predicts motor ski...
Automatic extraction of region objects from high-resolution satellite imagery presents a great challenge, because there may be very large variations of the objects in terms of their size, texture, shape, and contextual complexity in the image. To han...
Children’s graphic development reflects cognitive, emotional, motor and social processes, and is an indicator of the infant’s integral development. This study analyzed the validity of Viktor Lowenfeld’s developmental model in childr...
Drawings have been widely used as a window to the mind; as such, they can reveal some aspects of the cognitive and emotional worlds of other animals that can produce them. The study of non-human drawings, however, is limited by human perception, whic...
As a recognized type of art, graffiti is a cultural asset and an important aspect of a city’s aesthetics. As such, graffiti is associated with social and commercial vibrancy and is known to attract tourists. However, positional uncertainty and...
The Yenyuan stream salamander (Batrachuperus yenyuanensis) has been previously evaluated with regards to phylogeny, population genetics, and hematology, but genomic information is sparse due to the giant genome size of salamanders which contain highl...
In rapidly urbanizing areas, natural vegetation becomes fragmented, making conservation planning challenging, particularly as climate change accelerates fire risk. We studied urban forest fragments in two threatened eucalypt-dominated (scribbly gum w...
This paper defines the term “graffiti” and outlines the origins of this concept. The terminological arrangement allowed for the subject of this research, i.e., illegal graffiti, to be situated in reality, i.e., an urban space. It was assu...