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19 pages, 1090 KiB  
Article
Inbound Truck Scheduling for Workload Balancing in Cross-Docking Terminals
by Younghoo Noh, Seokchan Lee, Jeongyoon Hong, Jeongeum Kim and Sung Won Cho
Mathematics 2025, 13(15), 2533; https://doi.org/10.3390/math13152533 - 6 Aug 2025
Abstract
The rapid growth of e-commerce and advances in information and communication technologies have placed increasing pressure on last-mile delivery companies to enhance operational productivity. As investments in logistics infrastructure require long-term planning, maximizing the efficiency of existing terminal operations has become a critical [...] Read more.
The rapid growth of e-commerce and advances in information and communication technologies have placed increasing pressure on last-mile delivery companies to enhance operational productivity. As investments in logistics infrastructure require long-term planning, maximizing the efficiency of existing terminal operations has become a critical priority. This study proposes a mathematical model for inbound truck scheduling that simultaneously minimizes truck waiting times and balances workload across temporary inventory storage located at outbound chutes in cross-docking terminals. The model incorporates a dynamic rescheduling strategy that updates the assignment of inbound trucks in real time, based on the latest terminal conditions. Numerical experiments, based on real operational data, demonstrate that the proposed approach significantly outperforms conventional strategies such as First-In First-Out (FIFO) and Random assignment in terms of both load balancing and truck turnaround efficiency. In particular, the proposed model improves workload balance by approximately 10% and 12% compared to the FIFO and Random strategies, respectively, and it reduces average truck waiting time by 17% and 18%, thereby contributing to more efficient workflow and alleviating bottlenecks. The findings highlight the practical potential of the proposed strategy for improving the responsiveness and efficiency of parcel distribution centers operating under fixed infrastructure constraints. Future research may extend the proposed approach by incorporating realistic operational factors, such as cargo heterogeneity, uncertain arrivals, and terminal shutdowns due to limited chute storage. Full article
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22 pages, 2208 KiB  
Article
Macroeconomic Effects of Oil Price Shocks in the Context of Geopolitical Events: Evidence from Selected European Countries
by Mariola Piłatowska and Andrzej Geise
Energies 2025, 18(15), 4165; https://doi.org/10.3390/en18154165 - 6 Aug 2025
Abstract
For a long time, the explanation of the various determinants of oil price fluctuations and their impact on economic activity has been based on the supply and demand mechanism. However, with various volatile changes in the international situation in recent years, such as [...] Read more.
For a long time, the explanation of the various determinants of oil price fluctuations and their impact on economic activity has been based on the supply and demand mechanism. However, with various volatile changes in the international situation in recent years, such as threats to public health and an increase in regional conflicts, special attention has been paid to the geopolitical context as an additional driver of oil price fluctuations. This study examines the relationship between oil price changes and GDP growth and other macroeconomic variables from the perspective of the vulnerability of oil-importing and oil-exporting countries to unexpected oil price shocks, driven by tense geopolitical events, in three European countries (Norway, Germany, and Poland). We apply the Structural Vector Autoregressive (SVAR) model and orthogonalized impulse response functions, based on quarterly data, in regard to two samples: the first spans 1995Q1–2019Q4 (pre-2020 sample), with relatively gradual changes in oil prices, and the second spans 1995Q1–2024Q2 (whole sample), with sudden fluctuations in oil prices due to geopolitical developments. A key finding of this research is that vulnerability to unpredictable oil price shocks related to geopolitical tensions is higher than in regard to expected gradual changes in oil prices, both in oil-importing and oil-exporting countries. Different causality patterns and stronger responses in regard to GDP growth during the period, including in regard to tense geopolitical events in comparison to the pre-2020 sample, lead to the belief that economies are not more resilient to oil price shocks as has been suggested by some studies, which referred to periods that were not driven by geopolitical events. Our research also suggests that countries implementing policies to reduce oil dependency and promote investment in alternative energy sources are better equipped to mitigate the adverse effects of oil price shocks. Full article
(This article belongs to the Special Issue Energy and Environmental Economic Theory and Policy)
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36 pages, 5151 KiB  
Article
Flexibility Resource Planning and Stability Optimization Methods for Power Systems with High Penetration of Renewable Energy
by Haiteng Han, Xiangchen Jiang, Yang Cao, Xuanyao Luo, Sheng Liu and Bei Yang
Energies 2025, 18(15), 4139; https://doi.org/10.3390/en18154139 - 4 Aug 2025
Viewed by 180
Abstract
With the accelerating global transition toward sustainable energy systems, power grids with a high share of renewable energy face increasing challenges due to volatility and uncertainty, necessitating advanced flexibility resource planning and stability optimization strategies. This paper presents a comprehensive distribution network planning [...] Read more.
With the accelerating global transition toward sustainable energy systems, power grids with a high share of renewable energy face increasing challenges due to volatility and uncertainty, necessitating advanced flexibility resource planning and stability optimization strategies. This paper presents a comprehensive distribution network planning framework that coordinates and integrates multiple types of flexibility resources through joint optimization and network reconfiguration to enhance system adaptability and operational resilience. A novel virtual network coupling modeling approach is proposed to address topological constraints during network reconfiguration, ensuring radial operation while allowing rapid topology adjustments to isolate faults and restore power supply. Furthermore, to mitigate the uncertainty and fault risks associated with extreme weather events, a CVaR-based risk quantification framework is incorporated into a bi-level optimization model, effectively balancing investment costs and operational risks under uncertainty. In this model, the upper-level planning stage optimizes the siting and sizing of flexibility resources, while the lower-level operational stage coordinates real-time dispatch strategies through demand response, energy storage operation, and dynamic network reconfiguration. Finally, a hybrid SA-PSO algorithm combined with conic programming is employed to enhance computational efficiency while ensuring high solution quality for practical system scales. Case study analyses demonstrate that, compared to single-resource configurations, the proposed coordinated planning of multiple flexibility resources can significantly reduce the total system cost and markedly improve system resilience under fault conditions. Full article
(This article belongs to the Special Issue Analysis and Control of Power System Stability)
21 pages, 1141 KiB  
Article
Monthly Load Forecasting in a Region Experiencing Demand Growth: A Case Study of Texas
by Jeong-Hee Hong and Geun-Cheol Lee
Energies 2025, 18(15), 4135; https://doi.org/10.3390/en18154135 - 4 Aug 2025
Viewed by 195
Abstract
In this study, we consider monthly load forecasting, which is an essential decision for energy infrastructure planning and investment. This study focuses on the Texas power grid, where electricity consumption has surged due to rising industrial activity and the increased construction of data [...] Read more.
In this study, we consider monthly load forecasting, which is an essential decision for energy infrastructure planning and investment. This study focuses on the Texas power grid, where electricity consumption has surged due to rising industrial activity and the increased construction of data centers driven by growing demand for AI. Based on an extensive exploratory data analysis, we identify key characteristics of monthly electricity demand in Texas, including an accelerating upward trend, strong seasonality, and temperature sensitivity. In response, we propose a regression-based forecasting model that incorporates a carefully designed set of input features, including a nonlinear trend, lagged demand variables, a seasonality-adjusted month variable, average temperature of a representative area, and calendar-based proxies for industrial activity. We adopt a rolling forecasting approach, generating 12-month-ahead forecasts for both 2023 and 2024 using monthly data from 2013 onward. Comparative experiments against benchmarks including Holt–Winters, SARIMA, Prophet, RNN, LSTM, Transformer, Random Forest, LightGBM, and XGBoost show that the proposed model achieves superior performance with a mean absolute percentage error of approximately 2%. The results indicate that a well-designed regression approach can effectively outperform even the latest machine learning methods in monthly load forecasting. Full article
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25 pages, 5531 KiB  
Article
Transitions of Carbon Dioxide Emissions in China: K-Means Clustering and Discrete Endogenous Markov Chain Approach
by Shangyu Chen, Xiaoyu Kang and Sung Y. Park
Climate 2025, 13(8), 165; https://doi.org/10.3390/cli13080165 - 3 Aug 2025
Viewed by 175
Abstract
This study employs k-means clustering to group 30 Chinese provinces into four CO2 emission patterns, characterized by increasing emission levels and distinct energy consumption structures, and captures their dynamic evolution from 2000 to 2021 using a discrete endogenous Markov chain approach. While [...] Read more.
This study employs k-means clustering to group 30 Chinese provinces into four CO2 emission patterns, characterized by increasing emission levels and distinct energy consumption structures, and captures their dynamic evolution from 2000 to 2021 using a discrete endogenous Markov chain approach. While Shanghai, Jiangxi, and Hebei retained their original classifications, provinces such as Beijing, Fujian, Tianjin, and Anhui transitioned from higher to lower emission patterns, indicating notable reversals in emission trajectories. To identify the determinants of these transitions, GDP growth rate, population growth rate, and energy investment are incorporated as time varying covariates. The empirical findings demonstrate that GDP growth substantially increases interpattern mobility, thereby weakening state persistence, whereas population growth and energy investment tend to reinforce emission pattern stability. These results imply that policy responses must be tailored to regional dynamics. In rapidly growing regions, fiscal incentives and technological upgrading may facilitate downward transitions in emission states, whereas in provinces where emissions remain persistent due to demographic or investment related rigidity, structural adjustments and long term mitigation frameworks are essential. The study underscores the importance of integrating economic, demographic, and investment characteristics into carbon reduction strategies through a region specific and data informed approach. Full article
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13 pages, 2838 KiB  
Article
Differential Effects of Two Herbivore-Induced Plant Volatiles on the Oviposition of Chilo suppressalis
by Xiaowei Yang, Chang Liu, Xixi Jia, Chen Zhang, Lanzhi Han, Wanlun Cai and Yunhe Li
Plants 2025, 14(15), 2384; https://doi.org/10.3390/plants14152384 - 2 Aug 2025
Viewed by 229
Abstract
Herbivore-induced plant volatiles (HIPVs) are well known for their roles in herbivore deterrence and attraction of natural enemies, but their direct impact on insect reproduction remains largely unexplored. In this study, we provide novel evidence that two representative HIPVs, 2-heptanol and α-cedrene, exert [...] Read more.
Herbivore-induced plant volatiles (HIPVs) are well known for their roles in herbivore deterrence and attraction of natural enemies, but their direct impact on insect reproduction remains largely unexplored. In this study, we provide novel evidence that two representative HIPVs, 2-heptanol and α-cedrene, exert opposing effects on the reproduction of Chilo suppressalis, a major rice pest. While both volatiles repelled adults, α-cedrene unexpectedly enhanced oviposition, whereas 2-heptanol significantly suppressed egg laying. To examine these effects, we conducted oviposition assays, preoviposition and longevity tests, combined with qPCR and transcriptome analyses to explore underlying molecular responses. Mechanistically, α-cedrene upregulated Kr-h1, a gene linked to juvenile hormone signaling and vitellogenesis, promoting reproductive investment. Transcriptomic profiling revealed divergent molecular responses: α-cedrene activated reproductive pathways, whereas 2-heptanol induced stress- and immune-related genes, suggesting a trade-off between stress defense and reproduction. These findings demonstrate that HIPVs can exert compound-specific reproductive effects beyond repellency. This work fills a key knowledge gap and highlights the potential of HIPVs as precision tools in pest management strategies that exploit behavioral and physiological vulnerabilities beyond repellency. Full article
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18 pages, 475 KiB  
Article
How Environmental Turbulence Shapes the Path from Resilience to Sustainability: Useful Insights Gathered from Small and Medium Enterprises (SMEs)
by Ahmet Serdar İbrahimcioğlu and Hakan Kitapçı
Sustainability 2025, 17(15), 6938; https://doi.org/10.3390/su17156938 - 30 Jul 2025
Viewed by 207
Abstract
In the context of small and medium-sized enterprises (SMEs), organizational resilience has emerged as a critical capability for navigating dynamic and turbulent environments. The ability of firms to sustain their performance despite external disruptions, particularly those arising from market and technological change, is [...] Read more.
In the context of small and medium-sized enterprises (SMEs), organizational resilience has emerged as a critical capability for navigating dynamic and turbulent environments. The ability of firms to sustain their performance despite external disruptions, particularly those arising from market and technological change, is paramount for achieving long-term sustainability. This study offers a novel contribution by examining how two key dimensions of environmental turbulence—market turbulence and technological turbulence—moderate the relationship between organizational resilience capacity and sustainability performance. Our empirical findings, based on data from 423 SMEs, demonstrate that while organizational resilience positively correlates with sustainability performance, this relationship is significantly weakened under high levels of market and technological turbulence, indicating a negative moderating effect. These results advance resource-based and dynamic capabilities theory by highlighting the contingent nature of resilience in unstable contexts. Furthermore, this study provides practical guidance. SMEs should strategically invest in resilience-building efforts and continuously adapt their strategies in response to environmental fluctuations. Targeted approaches to managing different forms of turbulence and forming resilience-oriented collaborations can enhance sustainability outcomes. This research makes significant contributions to theory and practice; however, there are limitations that future research should take into account in order to appropriately utilize this study’s findings. Full article
(This article belongs to the Section Economic and Business Aspects of Sustainability)
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21 pages, 727 KiB  
Article
Cost-Effective Energy Retrofit Pathways for Buildings: A Case Study in Greece
by Charikleia Karakosta and Isaak Vryzidis
Energies 2025, 18(15), 4014; https://doi.org/10.3390/en18154014 - 28 Jul 2025
Viewed by 219
Abstract
Urban areas are responsible for most of Europe’s energy demand and emissions and urgently require building retrofits to meet climate neutrality goals. This study evaluates the energy efficiency potential of three public school buildings in western Macedonia, Greece—a cold-climate region with high heating [...] Read more.
Urban areas are responsible for most of Europe’s energy demand and emissions and urgently require building retrofits to meet climate neutrality goals. This study evaluates the energy efficiency potential of three public school buildings in western Macedonia, Greece—a cold-climate region with high heating needs. The buildings, constructed between 1986 and 2003, exhibited poor insulation, outdated electromechanical systems, and inefficient lighting, resulting in high oil consumption and low energy ratings. A robust methodology is applied, combining detailed on-site energy audits, thermophysical diagnostics based on U-value calculations, and a techno-economic assessment utilizing Net Present Value (NPV), Internal Rate of Return (IRR), and SWOT analysis. The study evaluates a series of retrofit measures, including ceiling insulation, high-efficiency lighting replacements, and boiler modernization, against both technical performance criteria and financial viability. Results indicate that ceiling insulation and lighting system upgrades yield positive economic returns, while wall and floor insulation measures remain financially unattractive without external subsidies. The findings are further validated through sensitivity analysis and policy scenario modeling, revealing how targeted investments, especially when supported by public funding schemes, can maximize energy savings and emissions reductions. The study concludes that selective implementation of cost-effective measures, supported by public grants, can achieve energy targets, improve indoor environments, and serve as a replicable model of targeted retrofits across the region, though reliance on external funding and high upfront costs pose challenges. Full article
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24 pages, 2710 KiB  
Article
Spatial and Economic-Based Clustering of Greek Irrigation Water Organizations: A Data-Driven Framework for Sustainable Water Pricing and Policy Reform
by Dimitrios Tsagkoudis, Eleni Zafeiriou and Konstantinos Spinthiropoulos
Water 2025, 17(15), 2242; https://doi.org/10.3390/w17152242 - 28 Jul 2025
Viewed by 338
Abstract
This study employs k-means clustering to analyze local organizations responsible for land improvement in Greece, identifying four distinct groups with consistent geographic patterns but divergent financial and operational characteristics. By integrating unsupervised machine learning with spatial analysis, the research offers a novel perspective [...] Read more.
This study employs k-means clustering to analyze local organizations responsible for land improvement in Greece, identifying four distinct groups with consistent geographic patterns but divergent financial and operational characteristics. By integrating unsupervised machine learning with spatial analysis, the research offers a novel perspective on irrigation water pricing and cost recovery. The findings reveal that organizations located on islands, despite high water costs due to limited rainfall and geographic isolation, tend to achieve relatively strong financial performance, indicating the presence of adaptive mechanisms that could inform broader policy strategies. In contrast, organizations managing extensive irrigable land or large volumes of water frequently show poor cost recovery, challenging assumptions about economies of scale and revealing inefficiencies in pricing or governance structures. The spatial coherence of the clusters underscores the importance of geography in shaping institutional outcomes, reaffirming that environmental and locational factors can offer greater explanatory power than algorithmic models alone. This highlights the need for water management policies that move beyond uniform national strategies and instead reflect regional climatic, infrastructural, and economic variability. The study suggests several policy directions, including targeted infrastructure investment, locally calibrated water pricing models, and performance benchmarking based on successful organizational practices. Although grounded in the Greek context, the methodology and insights are transferable to other European and Mediterranean regions facing similar water governance challenges. Recognizing the limitations of the current analysis—including gaps in data consistency and the exclusion of socio-environmental indicators—the study advocates for future research incorporating broader variables and international comparative approaches. Ultimately, it supports a hybrid policy framework that combines data-driven analysis with spatial intelligence to promote sustainability, equity, and financial viability in agricultural water management. Full article
(This article belongs to the Special Issue Balancing Competing Demands for Sustainable Water Development)
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21 pages, 979 KiB  
Article
AI-Enhanced Coastal Flood Risk Assessment: A Real-Time Web Platform with Multi-Source Integration and Chesapeake Bay Case Study
by Paul Magoulick
Water 2025, 17(15), 2231; https://doi.org/10.3390/w17152231 - 26 Jul 2025
Viewed by 338
Abstract
A critical gap exists between coastal communities’ need for accessible flood risk assessment tools and the availability of sophisticated modeling, which remains limited by technical barriers and computational demands. This study introduces three key innovations through Coastal Defense Pro: (1) the first operational [...] Read more.
A critical gap exists between coastal communities’ need for accessible flood risk assessment tools and the availability of sophisticated modeling, which remains limited by technical barriers and computational demands. This study introduces three key innovations through Coastal Defense Pro: (1) the first operational web-based AI ensemble for coastal flood risk assessment integrating real-time multi-agency data, (2) an automated regional calibration system that corrects systematic model biases through machine learning, and (3) browser-accessible implementation of research-grade modeling previously requiring specialized computational resources. The system combines Bayesian neural networks with optional LSTM and attention-based models, implementing automatic regional calibration and multi-source elevation consensus through a modular Python architecture. Real-time API integration achieves >99% system uptime with sub-3-second response times via intelligent caching. Validation against Hurricane Isabel (2003) demonstrates correction from 197% overprediction (6.92 m predicted vs. 2.33 m observed) to accurate prediction through automated identification of a Chesapeake Bay-specific reduction factor of 0.337. Comprehensive validation against 15 major storms (1992–2024) shows substantial improvement over standard methods (RMSE = 0.436 m vs. 2.267 m; R2 = 0.934 vs. −0.786). Economic assessment using NACCS fragility curves demonstrates 12.7-year payback periods for flood protection investments. The open-source Streamlit implementation democratizes access to research-grade risk assessment, transforming months-long specialist analyses into immediate browser-based tools without compromising scientific rigor. Full article
(This article belongs to the Special Issue Coastal Flood Hazard Risk Assessment and Mitigation Strategies)
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20 pages, 1026 KiB  
Article
Spatial Variations in Perceptions of Decarbonization Impacts and Public Acceptance of the Bioeconomy in Western Macedonia
by Christina-Ioanna Papadopoulou, Stavros Kalogiannidis, Dimitrios Kalfas, Efstratios Loizou and Fotios Chatzitheodoridis
Land 2025, 14(8), 1533; https://doi.org/10.3390/land14081533 - 25 Jul 2025
Viewed by 198
Abstract
This study examines the regional disparities in public perceptions of decarbonization and the acceptance of the bioeconomy within Western Macedonia, a Greek region undergoing structural economic change. While the environmental benefits of decarbonization, such as reduced carbon emissions and improved air quality, are [...] Read more.
This study examines the regional disparities in public perceptions of decarbonization and the acceptance of the bioeconomy within Western Macedonia, a Greek region undergoing structural economic change. While the environmental benefits of decarbonization, such as reduced carbon emissions and improved air quality, are widely acknowledged, perceptions of economic and social outcomes, including investments, new business development, and policy support, vary significantly across sub-regions. To this end, a structured survey was conducted among 765 residents, utilizing Likert-scale items to assess attitudes, with demographic data providing a contextual framework. Statistical analyses, incorporating techniques such as one-way analysis of variance (ANOVA), Kruskal–Wallis, and multiple regression, were employed to explore spatial variations and identify the primary drivers of bioeconomy acceptance. The results indicate that perceived government action, visible investment, new enterprises, and a positive view of public sentiment are all significant predictors of acceptance, with institutional support showing the strongest influence. The findings reveal that certain areas feel less engaged in the transition, expressing skepticism about its benefits, while others report more optimism. This disparity in perception underscores the necessity for targeted policy interventions to ensure inclusive and equitable participation. The study emphasizes the necessity for regionally responsive governance, enhanced communication strategies, and tangible local development initiatives to cultivate public trust and support. The study makes a significant contribution to the broader discourse on just transitions by emphasizing the role of place-based perceptions in shaping sustainable change. Full article
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21 pages, 4393 KiB  
Article
Lightweight and Sustainable Steering Knuckle via Topology Optimization and Rapid Investment Casting
by Daniele Almonti, Daniel Salvi, Emanuele Mingione and Silvia Vesco
J. Manuf. Mater. Process. 2025, 9(8), 252; https://doi.org/10.3390/jmmp9080252 - 24 Jul 2025
Viewed by 443
Abstract
Considering the importance of the automotive industry, reducing the environmental impact of automotive component manufacturing is crucial. Additionally, lightening of the latter promotes a reduction in fuel consumption throughout the vehicle’s life cycle, limiting emissions. This study presents a comprehensive approach to optimizing [...] Read more.
Considering the importance of the automotive industry, reducing the environmental impact of automotive component manufacturing is crucial. Additionally, lightening of the latter promotes a reduction in fuel consumption throughout the vehicle’s life cycle, limiting emissions. This study presents a comprehensive approach to optimizing and manufacturing a MacPherson steering knuckle using topology optimization (TO), additive manufacturing, and rapid investment casting (RIC). Static structural simulations confirmed the mechanical integrity of the optimized design, with stress and strain values remaining within the elastic limits of the SG A536 iron alloy. The TO process achieved a 30% reduction in mass, resulting in lower material use and production costs. Additive manufacturing of optimized geometry reduced resin consumption by 27% and printing time by 9%. RIC simulations validated efficient mold filling and solidification, with porosity confined to removable riser regions. Life cycle assessment (LCA) demonstrated a 27% reduction in manufacturing environmental impact and a 31% decrease throughout the component life cycle, largely due to vehicle lightweighting. The findings highlight the potential of integrated TO and advanced manufacturing techniques to produce structurally efficient and environmentally sustainable automotive components. This workflow offers promising implications for broader industrial applications that aim to balance mechanical performance with ecological responsibility. Full article
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30 pages, 906 KiB  
Article
The Impact of Carbon Trading Market on the Layout Decision of Renewable Energy Investment—Theoretical Modeling and Case Study
by Ning Yan, Shenhai Huang, Yan Chen, Daini Zhang, Qin Xu, Xiangyi Yang and Shiyan Wen
Energies 2025, 18(15), 3950; https://doi.org/10.3390/en18153950 - 24 Jul 2025
Viewed by 297
Abstract
The Carbon Emissions Trading System (ETS) serves as a market-based mechanism to drive renewable energy (RE) investments, yet its heterogeneous impacts on different stakeholders remain underexplored. This paper treats the carbon market as an exogenous shock and develops a multi-agent equilibrium model incorporating [...] Read more.
The Carbon Emissions Trading System (ETS) serves as a market-based mechanism to drive renewable energy (RE) investments, yet its heterogeneous impacts on different stakeholders remain underexplored. This paper treats the carbon market as an exogenous shock and develops a multi-agent equilibrium model incorporating carbon pricing, encompassing power generation enterprises, power transmission enterprises, power consumers, and the government, to analyze how carbon prices reshape RE investment layouts under dual-carbon goals. Using panel data from Zhejiang Province (2017–2022), a high-energy-consumption region with 25% net electricity imports, we simulate heterogeneous responses of agents to carbon price fluctuations (CNY 50–250/ton). The results show that RE on-grid electricity increases (+0.55% to +2.89%), while thermal power declines (–4.98% to −15.39%) on the generation side. Transmission-side RE sales rise (+3.25% to +9.74%), though total electricity sales decrease (−0.49% to −2.22%). On the consumption side, RE self-generation grows (+2.12% to +5.93%), yet higher carbon prices reduce overall utility (−0.44% to −2.05%). Furthermore, external electricity integration (peaking at 28.5% of sales in 2020) alleviates provincial entities’ carbon cost pressure under high carbon prices. This study offers systematic insights for renewable energy investment decisions and policy optimization. Full article
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18 pages, 692 KiB  
Review
Literature Review and Policy Recommendations for Single-Dose HPV Vaccination Schedule in China: Opportunities and Challenges
by Kexin Cao and Yiu-Wing Kam
Vaccines 2025, 13(8), 786; https://doi.org/10.3390/vaccines13080786 - 24 Jul 2025
Viewed by 748
Abstract
Cervical cancer remains a significant global public health challenge, with human papillomavirus (HPV) as its primary cause. In response, the World Health Organization (WHO) launched a global strategy to eliminate cervical cancer by 2030 and, in its 2022 position paper, recommended a single-dose [...] Read more.
Cervical cancer remains a significant global public health challenge, with human papillomavirus (HPV) as its primary cause. In response, the World Health Organization (WHO) launched a global strategy to eliminate cervical cancer by 2030 and, in its 2022 position paper, recommended a single-dose vaccination schedule. The objective of this review is to critically examine the current HPV vaccination landscape in China, including vaccination policies, immunization schedules, supply–demand dynamics, and the feasibility of transitioning to a single-dose regimen. By synthesizing recent developments in HPV virology, epidemiology, vaccine types, and immunization strategies, we identify both opportunities and barriers unique to the Chinese context. Results indicate that China primarily adheres to a three-dose vaccination schedule, with an optional two-dose schedule for girls aged 9–14, leaving a notable gap compared to the most recent WHO recommendation. The high prevalence of HPV types 52 and 58 contributes to a distinct regional infection pattern, underscoring the specific need for nine-valent vaccines tailored to China’s epidemiological profile. Despite the growing demand, vaccine supply remains inadequate, with an estimated annual shortfall of more than 15 million doses. This issue is further complicated by strong public preference for the nine-valent vaccine and the relatively high cost of vaccination. Emerging evidence supports the comparable efficacy and durable protection of a single-dose schedule, which could substantially reduce financial and logistical burdens while expanding coverage. This review advocates for the adoption of a simplified single-dose regimen, supported by catch-up strategies for older cohorts and the integration of HPV vaccination into China’s National Immunization Program (NIP). Sustained investment in domestic vaccine development and centralized procurement of imported vaccines may also possibly alleviate supply shortage. These coordinated efforts are critical for strengthening HPV-related disease prevention and accelerating China’s progress toward the WHO’s cervical cancer elimination targets. Full article
(This article belongs to the Special Issue Vaccination Strategies for Global Public Health)
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17 pages, 310 KiB  
Article
The Role of Public Health Informatics in the Coordination of Consistent Messaging from Local Health Departments and Public Health Partners During COVID-19
by Tran Ha Nguyen, Gulzar H. Shah, Indira Karibayeva and Bushra Shah
Information 2025, 16(8), 625; https://doi.org/10.3390/info16080625 - 22 Jul 2025
Viewed by 275
Abstract
Introduction: Efficient communication and collaboration among local health departments (LHDs), healthcare organizations, governmental entities, and other community stakeholders are critical for public health preparedness and response. This study evaluates (1) the impact of informatics on LHDs’ frequency and collaboration in creating consistent COVID-19 [...] Read more.
Introduction: Efficient communication and collaboration among local health departments (LHDs), healthcare organizations, governmental entities, and other community stakeholders are critical for public health preparedness and response. This study evaluates (1) the impact of informatics on LHDs’ frequency and collaboration in creating consistent COVID-19 messaging; (2) the influence of informatics on targeted messaging for vulnerable populations; and (3) LHD characteristics linked to their consistent and/or targeted messaging engagement. Methods: This study analyzed the 2020 National Association of County and City Health Officials (NACCHO) Forces of Change (FOC) survey, the COVID-19 Edition. Of the 2390 LHDs invited to complete the core questionnaire, 905 were asked to fill out the module questionnaire as well. The response rate for the core was 24% with 587 responses, while the module received 237 responses, achieving a 26% response rate. Descriptive analyses and six logistic regression models were utilized. Results: Over 80% (183) of LHDs collaborated regularly with public health partners, and 95% (222) used information management applications for COVID-19. Most interacted with local and state agencies, but only half with federal ones. LHDs that exchanged data with local non-health agencies, engaged with local non-health agencies, and communicated weekly to daily with the public about long-term/assisted care had higher odds of creating consistent messages for the public, and about the use and reuse of masks had lower odds of collaborating with public health partners to develop consistent messages for the public. Conclusion: Our findings underscore the centrality of informatics infrastructure and collaboration in ensuring equitable public health messaging. Strengthening public health agencies and investing in targeted training are crucial for effective communication across the communities served by these agencies. Full article
(This article belongs to the Special Issue Feature Papers in Information in 2024–2025)
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