Search Results (1,001)

Artificial gynogenesis is an essential technique for aquaculture breeding. Fertile offspring of the WuLi carp (Cyprinus carpio var. Quanzhounensis, 2n = 100, WLC) were successfully produced via gynogenesis using ultraviolet-irradiated sperm from the blunt snout bream (Megalobrama amblycephala, 2n = 48, BSB). As anticipated, gonadal section examination confirmed that all gynogenetic WuLi carp (2n = 100, GWB) were female. To investigate whether paternal DNA fragments from BSB were integrated into the GWB genome, comparative analyses of morphological traits, DNA content, chromosomal numbers, 5S rDNA sequences, microsatellite DNA markers, fluorescence in situ hybridization (FISH), growth performance and nutritional composition were systematically conducted between GWB and maternal WLC. The results revealed pronounced maternal inheritance patterns across morphological characteristics, DNA quantification, chromosomal configurations, 5S rDNA sequences and FISH signals, while microsatellite detection unequivocally confirmed paternal BSB DNA fragment integration into the GWB genome. Remarkably, GWB demonstrated significantly superior growth performance and elevated unsaturated fatty acid content relative to the maternal line. This approach not only addressed germplasm degradation in WLC but also provided valuable theoretical foundations for breeding programs in this commercially significant species. Full article

Monitoring sediment concentration in water bodies is crucial for assessing water quality, ecosystems, and environmental health. However, physical sampling and sensor-based approaches are labor-intensive and unsuitable for large-scale, continuous monitoring. This study employs machine learning models to estimate suspended sediment concentration using images captured in natural light, named RGB, and near-infrared (NIR) conditions. A controlled dataset of approximately 1300 images with SSC values ranging from 1000 mg/L to 150,000 mg/L was developed, incorporating temperature, time of image capture, and solar irradiance as additional features. Random forest regression and gradient boosting regression were trained on mean RGB values, red reflectance, time of captured, and temperature for natural light images, achieving up to 72.96% accuracy within a 30% relative error. In contrast, NIR images leveraged gray-level co-occurrence matrix texture features and temperature, reaching 83.08% accuracy. Comparative analysis showed that ensemble models outperformed deep learning models like Convolutional Neural Networks and Multi-Layer Perceptrons, which struggled with high-dimensional feature extraction. These findings suggest that using machine learning models and RGB and NIR imagery offers a scalable, non-invasive, and cost-effective way of sediment monitoring in support of water quality assessment and environmental management. Full article

Drosophila suzukii is an invasive pest of many fruit crops worldwide. Employing the Sterile Insect Technique (SIT) could mitigate D. suzukii population growth and crop damage. This study evaluated the efficacy of SIT on commercial fruit, by (1) validating the quality of irradiated sterile males (male mating competitiveness, courtship, and flight performance) in the laboratory, and (2) assessing population suppression and fruit damage reduction in commercial raspberry fields. Treatment with SIT was compared to the grower’s standard chemical insecticide program throughout the season. The principal metrics of efficacy were trap counts of wild adult female D. suzukii in crops and larvae per fruit during harvesting. These metrics together with monitoring of border areas allowed targeting of high-pressure areas with higher releases of sterile males, to maximise efficacy for a given release number. The sterile male D. suzukii were as competitive as their fertile non-irradiated counterparts in laboratory mating competitiveness and flight performance studies while fertility egg-to-pupae recovery was reduced by 99%. In commercial raspberry crops, season-long releases of sterile males significantly suppressed the wild D. suzukii population, compared to the grower standard control strategy; with up to 89% reduction in wild female D. suzukii and 80% decrease in numbers of larvae per harvested fruit. Additionally, relative fruit waste (i.e., percentage of harvested fruits rejected for sale) at harvest was reduced for early, mid and late harvest crops, by up to 58% compared to the grower standard control. SIT has the potential to provide an effective and sustainable strategy for managing D. suzukii in raspberries, increasing marketable yield by reducing adult populations, fruit damage and waste fruit. SIT could therefore serve as a valuable tool for integrated pest management practices in berry production systems. Full article

This study investigated the immunonutritional potential of high-molecular-weight (Mw~85 kDa), non-degraded chitosan (NCS) and gamma-radiation-degraded, low-molecular-weight chitosan (RCS) incorporated into aquafeeds for Nile tilapia (Oreochromis niloticus). RCS was produced by γ-irradiation (10 kGy) in the presence of 0.25% (w/v) H₂O₂, yielding low-viscosity, colloidally stable nanoparticles with Mw ranging from 10 to 13 kDa. Five diets were formulated: a control, NCS at 0.50%, and RCS at 0.025%, 0.050%, and 0.075%. No adverse effects on growth were observed, confirming safety. Immune gene expression (e.g., ifng1, nfκb, tnf), antioxidant markers (e.g., reduced MDA, increased GSH and GR), and nonspecific humoral responses (lysozyme, IgM, and bactericidal activity) were significantly enhanced in the NCS-0.50, RCS-0.050, and RCS-0.075 groups. Notably, these benefits were achieved with RCS at 10-fold lower concentrations than NCS. Following challenge with Edwardsiella tarda, fish fed RCS-0.050 and RCS-0.075 diets exhibited the highest survival rates and relative percent survival, highlighting robust activation of innate and adaptive immunity alongside redox defense. These results support the use of low-Mw RCS as a biologically potent, cost-effective alternative to traditional high-Mw chitosan in functional aquafeeds. RCS-0.050 and RCS-0.075 show strong potential as immunonutritional agents to enhance fish health and disease resistance in aquaculture. Full article

Poly(N-vinyl-2-pyrrolidone), or PVP, nanogels loaded with gadolinium nitrate (Gd(NO₃)₃·6H₂O) were synthesized by ionizing irradiation, aiming for potential applications in magnetic resonance imaging (MRI). A comprehensive characterization of PVP and Gd aqueous solutions with different VP-monomer-to-Gd ratios was conducted before and after irradiation. The results indicate a complexation between PVP and Gd ions before irradiation. The size of the nanogels exhibited a strong dependence on several factors, including PVP molecular weight, concentration, temperature, and the precise timing of Gd introduction relative to the irradiation process. A quantification study was conducted to investigate the impact of molecular weight, the VP/Gd ratio, and Gd addition before or after the irradiation process on the concentration of free Gd ions. These findings offer valuable insights into optimizing the synthesis of Gd-loaded PVP nanogels for potential applications, highlighting the critical factors that influence their size and stability. Full article

Photovoltaic (PV) systems are the core technology for implementing net-zero carbon emissions by 2050. The performance of PV systems is strongly influenced by environmental factors, including irradiance, temperature, and shading, which makes it difficult to characterize the nonlinear and multi-coupling behavior of the systems. Accurate modeling is essential for reliable performance prediction and lifespan estimation. To address this challenge, a novel metaheuristic algorithm called shuffled puma optimizer (SPO) is deployed to perform parameter extraction and optimal configuration identification across four PV models. The robustness and stability of SPO are comprehensively evaluated through comparisons with advanced algorithms based on best fitness, mean fitness, and standard deviation. The root mean square error (RMSE) obtained by SPO for parameter extraction are 8.8180 × 10⁻⁴, 8.5513 × 10⁻⁴, 8.4900 × 10⁻⁴, and 2.3941 × 10⁻³ for the single diode model (SDM), double diode model (DDM), triple diode model (TDM), and photovoltaic module model (PMM), respectively. A one-factor-at-a-time (OFAT) sensitivity analysis is employed to assess the relative importance of undetermined parameters within each PV model. The SPO-based modeling framework enables high-accuracy PV performance prediction, and its application to sensitivity analysis can accurately identify key factors that lead to reduced computational cost and improved adaptability for integration with energy management systems and intelligent electric grids. Full article

The rapid electrification of transportation and the proliferation of rooftop solar photovoltaics (PVs) in urban environments are reshaping the operational dynamics of power distribution networks. However, the inherent uncertainty in electric vehicle (EV) behavior—including arrival times, charging preferences, and state-of-charge—as well as spatially and temporally variable solar generation, presents a profound challenge to existing scheduling frameworks. This paper proposes a novel data-driven distributionally robust optimization (DDRO) framework for solar-powered EV charging coordination under spatiotemporal uncertainty. Leveraging empirical datasets of EV usage and solar irradiance from a smart city deployment, the framework constructs Wasserstein ambiguity sets around historical distributions, enabling worst-case-aware decision-making without requiring the assumption of probability laws. The problem is formulated as a two-stage optimization model. The first stage determines day-ahead charging schedules, solar utilization levels, and grid allocations across an urban-scale distribution feeder. The second stage models real-time recourse actions—such as dynamic curtailment or demand reshaping—after uncertainties are realized. Physical grid constraints are modeled using convexified LinDistFlow equations, while EV behavior is segmented into user classes with individualized uncertainty structures. The model is evaluated on a modified IEEE 123-bus feeder with 52 EV-PV nodes, using 15 min resolution over a 24 h horizon and 12 months of real-world data. Comparative results demonstrate that the proposed DDRO method reduces total operational costs by up to 15%, eliminates voltage violations entirely, and improves EV service satisfaction by more than 30% relative to deterministic and stochastic baselines. This work makes three primary contributions: it introduces a robust, tractable optimization architecture that captures spatiotemporal uncertainty using empirical Wasserstein sets; it integrates behavioral and physical modeling within a unified dispatch framework for urban energy-mobility systems; and it demonstrates the value of robust coordination in simultaneously improving grid resilience, renewable utilization, and EV user satisfaction. The results offer practical insights for city-scale planners seeking to enable the reliable and efficient electrification of mobility infrastructure under uncertainty. Full article

Background/Objectives: Within the range of spread-out Bragg peak (SOBP), LET (linear energy transfer) gradually increases from proton beam entrance point toward the beam exit direction. While it is expected that the change in LET would lead to correspondent change in RBE (relative biological effectiveness) on many human cell lines, the incomplete cell killing due to low LET can result in tumor recurrence. Hence, this study aimed to assess the RBE on different cancer cell lines along low-LET proton SOBP. Methods: The clonogenicity of A549 and Panc-1 cells after irradiation was evaluated for investigating cell radiosensitivity in response to different types of radiation. The isoeffect doses of 6-MV photon and low-LET proton beams that resulted in equivalent cell surviving fractions at proton dose of 2 or 4 Gy were compared. Results: Ratios of α/β of A549 and Panc-1 cells from photon irradiation are 51.69 and −0.7747, respectively; RBE (2 Gy proton SOBP) on A549 and Panc-1 cells are 0.7403 ± 0.3324 and 1.0986 ± 0.3984, respectively. In addition, the change in RBE with proton LET was in a cell-specific and dose-dependent manner (LET-RBE linear correlations: A549 cells [r = 0.4673, p = 0.2430] vs. Panc-1 cells at 4 Gy [r = 0.7085, p = 0.0492]; Panc-1 cells at 2 Gy [r = −0.4123, p = 0.3100] vs. 4 Gy [r = 0.7085, p = 0.0492]). Conclusions: Compared with A549 cells, Panc-1 cells present greater resistance to low-LET proton beams. In addition, currently employed generic RBE value at 1.1 for proton therapy neglected the variation in cell-/tumor-specific radiobiological responses toward different dose levels of proton beams. Full article

Refractory high-entropy alloys (HEAs) are promising candidates for next-generation nuclear applications, particularly fusion reactors, due to their excellent high-temperature mechanical properties and irradiation resistance. Here, the microstructure and mechanical behavior were investigated for an equimolar WTaTiVZr HEA, designed from a palette of low-activation elements. The as-cast alloy exhibited a dendritic microstructure composed of W-Ta rich dendrites and Zr-Ti-V rich inter-dendritic regions, both possessing a body-centered cubic (BCC) crystal structure. Room temperature bulk compression tests showed ultra-high strength of around 1.6 GPa and plastic strain ~6%, with fracture surfaces showing cleavage facets. The alloy also demonstrated excellent high-temperature strength of ~650 MPa at 500 °C. Scratch-based fracture toughness was ~38 MPa√m for the as-cast WTaTiVZr HEA compared to ~25 MPa√m for commercially used pure tungsten. This higher value of fracture toughness indicates superior damage tolerance relative to commercially used pure tungsten. These results highlight the alloy’s potential as a low-activation structural material for high-temperature plasma-facing components (PFCs) in fusion reactors. Full article

The Earth Radiation Budget (ERB), a measure of the difference between incoming solar irradiance and outgoing reflected and emitted radiant energy, is a fundamental property of Earth’s climate system. The Libera satellite mission will measure the ERB’s outgoing components to continue the long-term climate data record established by NASA’s Clouds and the Earth’s Radiant Energy System (CERES) mission. In addition to ensuring data continuity, Libera will introduce a novel split-shortwave spectral channel to quantify the partitioning of the outgoing reflected solar component into visible and near-infrared sub-components. However, converting these split-shortwave radiances into the ERB-relevant irradiances requires the development of split-shortwave Angular Distribution Models (ADMs), which demand extensive angular sampling. Here, we show how Rotating Azimuthal Plane Scan (RAPS) parameters—specifically operational cadence and azimuthal scan rate—affect the observational coverage of a defined scene and angular space. Our results show that for a fixed number of azimuthal rotations, a relatively slow azimuthal scan rate of 0.5° per second, combined with more time spent in the RAPS observational mode, provides a more comprehensive sampling of the desired scene and angular space. We also show that operating the Libera instrument in RAPS mode at a cadence between every fifth day and every other day for the first year of space-based operations will provide sufficient scene and angular sampling for the observations to achieve radiance convergence for the scenes that comprise more than half of the expected Libera observations. Obtaining radiance convergence is necessary for accurate ADMs. Full article

This article presents the results of studies of the degradation of the structure and mechanical properties of the core materials BN-350 fast neutron and research WWR-K reactors required to justify the service life extension of early-generation power and research reactors. Extending the service life of nuclear reactors is a modern problem, since most operating reactors are early-generation reactors that have exhausted their design lifespan. The possibility of extending the service life is largely determined by the condition of the structural materials of the nuclear facility, i.e., their residual resources must ensure safe operation of the reactor. For the SAV-1 alloy, the structural material of the WWR-K reactor, studies were conducted on witness samples which were in the active zone during its operation for 56 years. It was found that yield strength and tensile strength of the irradiated SAV-1 alloy decreased by 24–48%, and relative elongation decreased by ~2% compared to the unirradiated alloy. Inside the grains and along their boundaries, there were particles of secondary phases enriched with silicon, which is typical for aged aluminum alloys. For irradiated structural steels of power reactors, studied at 350–450 C, hardening and a damping nature of creep were revealed, caused by dispersion hardening and the Hall–Petch effect. Full article

Forecasting future solar power plant production is essential to continue the development of photovoltaic energy and increase its share in the energy mix for a more sustainable future. Accurate solar radiation forecasting greatly improves the balance maintenance between energy supply and demand and grid management performance. This study assesses the influence of input selection on short-term global horizontal irradiance (GHI) forecasting across two contrasting Algerian climates: arid Ghardaïa and coastal Algiers. Eight feature selection methods (Pearson, Spearman, Mutual Information (MI), LASSO, SHAP (GB and RF), and RFE (GB and RF)) are evaluated using a Gradient Boosting model over horizons from one to six hours ahead. Input relevance depends on both the location and forecast horizon. At t+1, MI achieves the best results in Ghardaïa (nMAE = 6.44%), while LASSO performs best in Algiers (nMAE = 10.82%). At t+6, SHAP- and RFE-based methods yield the lowest errors in Ghardaïa (nMAE = 17.17%), and RFE-GB leads in Algiers (nMAE = 28.13%). Although performance gaps between methods remain moderate, relative improvements reach up to 30.28% in Ghardaïa and 12.86% in Algiers. These findings confirm that feature selection significantly enhances accuracy (especially at extended horizons) and suggest that simpler methods such as MI or LASSO can remain effective, depending on the climate context and forecast horizon. Full article

The phototherapeutic applications of porphyrin-based nanoscale metal–organic frameworks (nMOFs) are limited by the poor penetration of conventional excitation light sources into biological tissues. Radiodynamic therapy (RDT), which directly excites photosensitizers using X-rays, can overcome the issue of tissue penetration. However, RDT faces the problems of low energy conversion efficiency, requiring a relatively high radiation dose, and the potential to cause damage to normal tissues. Researchers have found that by using some metals with high atomic numbers (high Z) as X-ray scintillators and coordinating them with porphyrin photosensitizers to form MOF materials, the excellent antitumor effect of radiotherapy (RT) and RDT can be achieved under low-dose X-ray irradiation, which can not only effectively avoid the penetration limitations of light excitation methods but also eliminate the defect issues associated with directly using X-rays to excite photosensitizers. This review summarizes the relevant research work in recent years, in which researchers have used metal ions with high Z, such as Hf⁴⁺, Th⁴⁺, Ta⁵⁺, and Bi³⁺, in coordination with carboxyl porphyrins to form MOF materials for combined RT and RDT toward various cancer cells. This review compares the therapeutic effects and advantages of using different high-Z metals and introduces the application of the heavy atom effect. Furthermore, it explores the introduction of a chemodynamic therapy (CDT) mechanism through iron coordination at the porphyrin center, along with optimization strategies such as oxygen delivery using hemoglobin to enhance the efficacy of these MOFs as radiosensitizers. This review also summarizes the potential of these materials in preclinical applications and highlights the current challenges they face. It is expected that the summary and prospects outlined in this review can further promote preclinical biomedical research into and the development of porphyrin-based nMOFs. Full article

Background/Objectives: Carbon-ion radiotherapy (CIRT) is a promising treatment option for unresectable locally recurrent rectal cancer (LRRC). However, CIRT is contraindicated in cases where recurrent tumors are attached to the intestine. To address this limitation, we developed a novel treatment strategy involving curative-dose CIRT to recurrent tumors, including the adjacent intestine, without dose constraints, followed by surgical resection of the irradiated intestine. This study aimed to assess the feasibility of this approach. Methods: Patients were eligible for this study if the distance between the unresectable recurrent tumor and the adjacent intestines was less than 3 mm. Between 2019 and 2023, twelve patients were enrolled. CIRT was administered at curative doses of 70.4 or 73.6 Gy (relative biologic effectiveness (RBE)), including the adjacent intestines, without dose constraints. Surgical resection was not intended to excise the tumor itself, but was performed solely to remove the irradiated intestines. Irradiated intestine resection was planned within eight weeks after the completion of CIRT. Results: All patients completed the scheduled treatment course. The median interval between completing CIRT and surgery was 4 (3–8) weeks. No patients experienced acute AEs related to CIRT. Regarding late AEs, two patients developed Grade I sciatic neuralgia, and one patient developed Grade III neuralgia. We considered this symptom, which later resulted in a limp in his left leg, acceptable because this patient could ambulate with assistance. Clavien–Dindo Grade III postoperative complications occurred in one patient. The median follow-up duration was 40 (20–60) months. One patient was diagnosed with in-field recurrence, and three patients were diagnosed with out-of-field recurrence. These patients received reirradiation with CIRT. Four patients experienced lung recurrence, and one patient died from rectal-cancer-specific causes. Conclusions: This novel treatment strategy may provide favorable outcomes for patients with unresectable LRRC. This approach can be applied to the currently accepted indications for CIRT, and we believe that CIRT is a feasible treatment option for future patients. Full article

With the development of alternative energy technologies, energy production from renewable sources is gaining wide application. One of the types of renewable energy sources is solar power. In the past 5 years, solar cells have become very popular for both private electricity microgeneration and large power plants. There are two main options for installing solar photovoltaic panels: on the roof of a house or the ground; on specially made frames. When installing solar cells on the roof, it is not always possible to choose a tilt angle that is appropriate for all seasons, since the angle is mainly adjusted to the plane of the roof. When installing solar cells on the ground, it is usually possible to choose both the orientation relative to the cardinal points and the tilt angle relative to the ground. There are various theories about the best tilt angle of solar cells for producing the most amount of energy during the year. Therefore, the aim of the present research study is to develop an original research methodology for determining an optimal tilt angle for solar cells. The research study examined six different tilt angles of solar cells, 0°, 30°, 35° 40° 45° and 50°, orienting the cells towards the south. The research study used 18 identical monocrystalline solar panels with a power of 20 W. Three solar panels were set at each angle. This way, the experiment had three replications at each angle of the solar cells. The measurements were recorded by a GWL840 data logger with an interval of 10 s. The experiment was conducted by placing all solar cell modules on the roof of the building at Lat. 56.66181° and Long. 23.75238°. During the experimental period, the highest efficiency was found for the solar panels set at 50° and 40°, reaching the total solar irradiation of 266.61 Wm⁻² and 266.27 Wm⁻², respectively. Full article