Search Results (634)

Research on commuting patterns has mainly focused on urban and metropolitan areas, and such studies are not typically applied to rural and small-town regions, where workers often face longer commutes due to limited job opportunities and inadequate public transportation. By using the Census Transportation Planning Package (CTPP) data, this research fills that gap by analyzing commuting behavior by ethnic group and industry in south-central Minnesota, which is a predominantly rural area of 13 counties in the United States. The results show that both white and minority groups in District 7 experienced an increase in excess commuting from 2006 to 2016, with the minority group in Nobles County showing a significantly higher rise. Analysis by industry reveals that excess commuting in the leisure and hospitality sector (including arts, entertainment, and food services) in Nobles County increased five-fold during this time, indicating a severe spatial mismatch between jobs and affordable housing. In contrast, manufacturing experienced a decline of 50%, possibly indicating better commuting efficiency or a loss of manufacturing jobs. These findings can help city and transportation planners conduct an in-depth analysis of rural-to-urban commuting patterns and develop potential solutions to improve rural transportation infrastructure and accessibility, such as promoting telecommuting and hybrid work options, expanding shuttle routes, and adding more on-demand transit services in rural areas. Full article

Against the backdrop of multifaceted strategies to combat climate change, understanding soil erosion’s role in carbon cycling is critical due to terrestrial carbon pool vulnerability. This study integrates bibliometric methods with visualization tools (CiteSpace, VOSviewer) to analyze 3880 Web of Science core publications (1994–2024, inclusive), constructing knowledge graphs and forecasting trends. The results show exponential publication growth, shifting from slow development (1994–2011) to rapid expansion (2012–2024), aligning with international climate policy milestones. The Chinese Academy of Sciences led productivity (519 articles), while the US demonstrated major influence (H-index 117; 52,297 citations), creating a China–US bipolar research pattern. It was also found that Dutch journals dominate this research field. A keyword analysis revealed a shift from erosion-driven carbon transport to ecosystem service assessments. Emerging hotspots include microbial community regulation, climate–erosion feedback, and model–policy integration, though developing country collaboration remains limited. Future research should prioritize isotope tracing, multiscale modeling, and studies in ecologically vulnerable regions to enhance global soil carbon management. This study provides a novel analytical framework and forward-looking perspective for the soil erosion research on soil carbon cycling, serving as an extension of climate change mitigation strategies. Full article

The Yangtze River Delta urban agglomeration, characterized by high population density, an advanced transportation system, and a concentration of industrial activity, is one of the regions severely affected by O₃ pollution in central and eastern China. Using data collected from 251 monitoring stations between 2015 and 2025, this paper analyzed the spatio-temporal variation of 8 h O₃ concentrations and instances of exceedance. On the basis of exploring the influence of meteorological factors on regional 8 h O₃ concentration, the potential source contribution areas of pollutants under the exceedance condition were investigated using the HYSPLIT model. The results indicate a rapid increase in the 8 h O₃ concentration at a rate of 0.91 ± 0.98 μg·m⁻³·a⁻¹, with the average number of days exceeding concentration standards reaching 41.05 in the Yangtze River Delta urban agglomeration. Spatially, the 8 h O₃ concentrations were higher in coastal areas and lower in inland regions, as well as elevated in plains compared to hilly terrains. This distribution was significantly distinct from the concentration growth trend characterized by higher levels in the northwest and lower levels in the southeast. Furthermore, it diverged from the spatial characteristics where exceedances primarily occurred in the heavily industrialized northeastern region and the lightly industrialized central region, indicating that the growth and exceedance of 8 h O₃ concentrations were influenced by disparate factors. Local human activities have intensified the emissions of ozone precursor substances, which could be the key driving factor for the significant increase in regional 8 h O₃ concentrations. In the context of high temperatures and low humidity, this has contributed to elevated levels of 8 h O₃ concentrations. When wind speeds were below 2.5 m·s⁻¹, the proportion of 8 h O₃ concentrations exceeding the standards was nearly 0 under almost calm wind conditions, and it showed an increasing trend with rising wind speeds, indicating that the potential precursor sources that caused high O₃ concentrations originated occasionally from inland regions, with very limited presence within the study area. This observation implies that the main cause of exceedances was the transport effect of pollution from outside the region. Therefore, it is recommended that the Yangtze River Delta urban agglomeration adopt economic and technological compensation mechanisms within and between regions to reduce the emission intensity of precursor substances in potential source areas, thereby effectively controlling O₃ concentrations and improving public living conditions and quality of life. Full article

Artisanal and small-scale gold mining (ASGM) in Burkina Faso increasingly relies on cyanide, intensifying concerns about environmental contamination and human exposure. This study assessed free cyanide levels in water and soil across three ASGM sites—Zougnazagmiline, Guido, and Galgouli. Water samples (surface and groundwater) and topsoil (0–20 cm) were analyzed using the pyridine–pyrazolone method. Data were statistically and spatially processed using SPSS version 29.0 and the Google Earth Engine in conjunction with QGIS version 3.34, respectively. A site conceptual model (SCM) was also developed, based on the literature review, field observations, and validation by multidisciplinary experts in public health, toxicology, ecotoxicology, environmental engineering, and the mining sector, through a semi-structured survey. The results showed that 9.26% of the water samples exceeded the WHO guideline (0.07 mg/L), with peaks of 1.084 mg/L in Guido and 2.42 mg/L in Galgouli. At Zougnazagmiline, the water type differences were significant (F = 64.13; p < 0.001), unlike the other sites. In the soil, 29.36% of the samples exceeded 0.5 mg/kg, with concentrations reaching 9.79 mg/kg in Galgouli. A spatial analysis revealed pollution concentrated near the mining areas but spreading to residential and agricultural zones. The validated SCM integrates pollution sources, transport mechanisms, exposure routes, and vulnerable populations, offering a structured tool for environmental monitoring and health risk assessment in cyanide-impacted mining regions. Full article

Accurately identifying the sources of fine particulate matter (PM_2.5) pollution is crucial for pollution control and public health protection. Taking the PM_2.5 pollution event that occurred in Suzhou in June 2023 as a typical case, this study analyzed the characteristics and components of PM_2.5, and quantified the contributions of meteorological conditions, regional transport, and local emissions to the summertime PM_2.5 surge in a typical Yangtze River Delta (YRD) city. Chemical composition analysis highlighted a sharp increase in nitrate ions (NO₃⁻, contributing up to 49% during peak pollution), with calcium ion (Ca²⁺) and sulfate ion (SO₄²⁻) concentrations rising to 2 times and 7.5 times those of clean periods, respectively. Results from the random forest model demonstrated that emission sources (74%) dominated this pollution episode, significantly surpassing the meteorological contribution (26%). The Weather Research and Forecasting model combined with the Community Multiscale Air Quality model (WRF–CMAQ) further revealed that local emissions contributed the most to PM_2.5 concentrations in Suzhou (46.3%), while external transport primarily originated from upwind cities such as Shanghai and Jiaxing. The findings indicate synergistic effects from dust sources, industrial emissions, and mobile sources. Validation using electricity consumption and key enterprise emission data confirmed that intensive local industrial activities exacerbated PM_2.5 accumulation. Recommendations include strengthening regulations on local industrial and mobile source emissions, and enhancing regional joint prevention and control mechanisms to mitigate cross-boundary transport impacts. Full article

The integration of shared autonomous vehicles into historic urban areas presents both opportunities and challenges. In heritage-rich environments like very old Asian (such as Suzhou old town, which serves as a use case example) or European (especially Mediterranean coastal cities) areas—characterized by narrow alleys, dense development, and sensitive cultural landscapes—shared autonomous vehicle adoption raises critical spatial and social questions. This study employs a qualitative, user-centered approach based on the ripple model to examine residents’ perceptions across four dimensions: residential patterns, parking land use, regional accessibility, and street-level infrastructure. Semi-structured interviews with 27 participants reveal five key findings: (1) public trust depends on transparent decision-making and safety guarantees; (2) shared autonomous vehicles may reshape generational residential clustering; (3) the short-term parking demand remains stable, but the long-term reuse of space is feasible; (4) shared autonomous vehicles could enhance accessibility in historic cores; (5) transport systems may evolve toward intelligent, human-centered designs. Based on these insights, the study proposes three strategies: (1) transparent risk assessment using explainable artificial intelligence and digital twins; (2) polycentric development to diversify land use; (3) hierarchical street retrofitting to balance mobility and preservation. While this study is limited by its qualitative scope and absence of simulation, it offers a framework for culturally sensitive, small-scale interventions supporting sustainable mobility transitions in historic urban contexts. Full article

Rapid urbanization and climate change pose significant challenges to air quality in arid metropolitan areas, with critical implications for public health and sustainable development. This study projects the evolution of air pollution in Riyadh, Saudi Arabia, through 2070 using an integrated modeling approach that combines CMIP6 climate projections with localized air quality data. We analyzed daily concentrations of major pollutants (SO₂, NO₂) across 15 strategically selected monitoring stations representing diverse urban environments, including traffic corridors, residential areas, healthcare facilities, and semi-natural zones. Climate data from two Earth System Models (CNRM-ESM2-1 and MPI-ESM1.2) were bias-corrected and integrated with historical pollution measurements (2000–2015) using hierarchical Bayesian statistical modeling under SSP2-4.5 and SSP5-8.5 emission scenarios. Our results revealed substantial deterioration in air quality, with projected increases of 80–130% for SO₂ and 45–55% for NO₂ concentrations by 2070 under high-emission scenarios. Spatial analysis demonstrated pronounced pollution gradients, with traffic corridors (Eastern Ring Road, Northern Ring Road, Southern Ring Road) and densely urbanized areas (King Fahad Road, Makkah Road) experiencing the most severe increases, exceeding WHO guidelines by factors of 2–3. Even semi-natural areas showed significant increases in pollution due to regional transport effects. The hierarchical Bayesian framework effectively quantified uncertainties while revealing consistent degradation trends across both climate models, with the MPI-ESM1.2 model showing a greater sensitivity to anthropogenic forcing. Future concentrations are projected to reach up to 70 μg m⁻³ for SO₂ and exceed 100 μg m⁻³ for NO₂ in heavily trafficked areas by 2070, representing 2–3 times the Traffic corridors showed concentration increases of 21–24% compared to historical baselines, with some stations (R5, R13, and R14) recording projected levels above 4.0 ppb for SO₂ under the SSP5-8.5 scenario. These findings highlight the urgent need for comprehensive emission reduction strategies, accelerated renewable energy transition, and reformed urban planning approaches in rapidly developing arid cities. Full article

Background/Objectives: Climate change is a major factor exacerbating non-communicable diseases (NCDs) such as cardiovascular diseases, neoplasms, respiratory diseases, and diabetes, especially in vulnerable Latin American regions. This study analyzes the impact of environmental exposures related to climate change on the NCD burden in eight Latin American countries by quantifying the disability-adjusted life years (DALYs) attributable to these factors. Using Global Burden of Disease (GBD) data (1990–2021), we performed multiple linear regression to assess associations between DALYs and environmental risk factors—air pollution (particulate matter, nitrogen dioxide), radon, lead, and extreme temperatures—in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, Peru, and Uruguay. The study included major NCDs, and the population was stratified by age and sex. Results: Ischemic heart disease was the leading cause of DALYs in most countries. Particulate matter pollution was the main environmental risk factor contributing to the NCD burden, mainly affecting cardiovascular and respiratory diseases. Mexico showed the highest DALYs from particulate and ozone pollution; temperature and lead exposure also contributed in some countries. Nitrogen dioxide was the primary risk factor for asthma. Statistically significant relationships between environmental factors and DALYs were confirmed. Conclusions: Climate change-related exposures significantly increase the burden of NCDs in Latin America. Targeted interventions in industry, transportation, and energy, along with sustainable urban policies, are essential to mitigate health impacts and reduce disparities. Integrating environmental health into public policies can improve health outcomes amid ongoing climate challenges. Full article

Increasing the use of healthcare facilities has resulted in the growing production of biomedical waste, which poses health risks to users, health professionals, and the environment. The aim of this research is to study the correlation between governance in Togo’s public health facilities and the quality of biomedical waste management within these facilities. Methods: This was a cross-sectional, descriptive, and analytical study conducted from September to December 2024. It involved 264 public health facilities of all types in all health regions of Togo. Health facilities were selected using the simple random selection technique. Healthcare providers were selected using the reasoned choice technique. The statistical tests used were the chi-square test and logistic regression, which enabled proportions to be compared and confounding factors to be eliminated, respectively. Results: Multivariate analysis revealed a statistically significant association between the organization and training component of governance and the quality of biomedical waste management (BMWM) in health facilities (OR = 3.79; 95% CI [1.79–8.03]; p < 0.001). This relationship suggests that health facilities with functional infection prevention and control (ICP) or BMWM committees, trained staff at all levels (nursing, technical, and administrative), and dedicated waste management personnel are more likely to implement compliant waste management practices. Analyses of the data also revealed that, among the criteria for assessing the quality of biomedical waste management (BMWM), the most significant were sorting (OR = 1.482; 95% CI [1.286; 1.708]), quantification (OR = 2.026; 95% CI [1.491; 2.753]), transportation (OR = 1.403; 95% CI [1.187; 1.66]), and disposal infrastructure (OR = 1.604; 95% CI [1.298; 1.982]). The application of this grid shows that 17.8% of the health facilities surveyed had a score equal to or above 80% on all the criteria used to assess the quality of biomedical waste management, and they were therefore managing waste in an “acceptable” manner. The study highlights key findings in biomedical waste management practices, providing actionable insights for improving public health safety. Full article

Urban public transport represents a fundamental pillar of a sustainable transport system and a key subsystem within the broader mobility framework in urban environments. This paper focuses on the analysis and optimization of the public transport system in the city of Prievidza and the nearby town of Bojnice in Slovakia, which currently face challenges such as low system attractiveness, operational inefficiency, and weak integration with regional railway transport. This study presents the results of a comprehensive analysis of existing public transport services in Prievidza and Bojnice, including an assessment of passenger flows, line network structure, transfer connections, and operational parameters. Based on the identified deficiencies, a new urban public transport network system is proposed, emphasizing direct links to the railway network. This methodology is developed in the context of an integrated timed-transfer timetable, with defined system time slots at the main transfer hub and a newly designed line network with standardized paths and regular intervals. The proposed system ensures significantly improved connectivity between urban transport and rail services, reduces deadhead kilometres, lowers the number of required vehicles, and leads to a reduction in operational costs by up to 20%. The resulting model serves as a transferable example of efficient service planning in medium-sized cities, with a focus on functional integration, operational efficiency, and sustainable urban development. Full article

Introduction: The interface between T cells and the tumor microenvironment, termed the ‘immunological synapse’, consists of multiple checkpoint protein pairs co-expressed on both sides of the synapse. mir-16, a microRNA from a widely known tumor-suppressor family of miRNAs, was previously shown by us to be downregulated in melanoma. As other miRNAs from this family have been shown to directly target checkpoint proteins, here we investigated whether miR-16 influences the expression patterns of checkpoint proteins in melanoma. Methods: Single-cell gene expression data from the melanoma microenvironment were retrieved from a public database. Melanoma cell lines were established from metastatic lesions and transiently transfected with an hsa-miR-16-5p-mimic RNA or a mir-16-expressing plasmid. The mRNA expression profiles were analyzed using an Affymetrix microarray. Direct targets of miR-16 were identified by luciferase reporter assays. Protein levels were assessed by Western blotting. Results: Bioinformatic analysis revealed that the expression levels of eight checkpoint mRNAs, known to be present on the melanoma side of the immunological synapse, were highly correlated. Four of these mRNAs contained putative binding sites for the miR-15/16 family. miR-16 expression was significantly reduced in melanoma cells, compared to normal melanocytes. Luciferase reporter assays demonstrated that miR-16 directly targets the 3′ untranslated regions (3′UTRs) of CD40, CD80. The mRNAs downregulated following miR-16 overexpression were highly enriched for genes involved in autophagy, vesicle-mediated transport, and the regulation of protein membrane localization. Among these, VTI1B and SMPD1 were confirmed to be direct targets of miR-16. Transient overexpression of miR-16 resulted in a significant reduction in SMPD1 and VTI1B levels in melanoma cell lines. Conclusions: Our findings suggest that miR-16 potentially modulates melanoma tumorigenesis, metastasis and immunogenicity by altering the composition of checkpoint proteins at the immunological synapse and by regulating cellular pathways associated with intracellular trafficking and transmembrane protein presentation. Full article

Artificial intelligence (AI) has the potential to significantly advance the management of nonpoint source pollution (NPSP), a critical environmental issue characterized by diffuse sources and complex transport mechanisms. This study systematically examines current AI applications addressing NPSP through bibliometric and systematic analyses. A total of 124 studies were included after rigorous identification, screening, and eligibility assessments based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) framework. Key findings from the bibliometric analysis include publication trends, regional research contributions, author and journal contributions, and core concepts in NPSP. The systematic analysis further provided: (a) a comprehensive synthesis of NPSP characterization, covering pollution sources, key drivers, pollutants, transport pathways, and environmental impacts; (b) identification of emerging AI technologies such as the Internet of Things, unmanned aerial vehicles, and geographic information systems, and their potential applications in NPSP contexts; (c) a detailed classification of AI models used in NPSP assessment, highlighting predictors, predictands, and performance metrics specifically in water quality prediction and monitoring, groundwater vulnerability mapping, and pollutant-specific modeling; and (d) a critical assessment of knowledge gaps categorized into AI model development and validation, data constraints, governance and policy challenges, and system integration, alongside proposed targeted future research directions emphasizing adaptive governance, transparent AI modeling, and interdisciplinary collaboration. The findings from this study provide essential insights for researchers, policymakers, environmental managers, and communities aiming to implement AI-driven strategies to mitigate NPSP. Full article

Urban park vitality, a key indicator of public space performance, has garnered significant research attention. However, existing studies often neglect the temporal variability in vitality patterns, thus failing to accurately reflect actual park performance and limiting their relevance for strategic urban planning and sustainable resource allocation. This study constructs a “temporal behavior–spatial attributes–park typology” framework using high-precision (50 m) mobile signaling data to capture hourly vitality fluctuations in 59 parks of Hangzhou’s Gongshu District. Using dynamic time-warping-optimized K-means clustering, we identify three vitality types—Morning-Exercise-Dominated, All-Day-Balanced, and Evening-Aggregation-Dominated—revealing distinct weekday/weekend usage rhythms linked to park typology (e.g., community vs. comprehensive parks). Geographical Detector analysis shows that vitality correlates with spatial attributes in time-specific ways; weekend morning vitality is driven by park size and surrounding POI density, while weekday evening vitality depends on interactions between facility density and residential population. These findings highlight how transportation accessibility and commercial amenities shape temporal vitality, informing time-sensitive strategies such as extended evening hours for suburban parks and targeted facility upgrades in residential areas. By bridging vitality patterns with strategic planning demands, the study advances the understanding of how sustainable park management can optimize resource efficiency and enhance public space equity, offering insights for urban green infrastructure planning in other regions. Full article

This study proposes a multi-dimensional urban transportation network optimization framework (MTNO-RQDC) to address structural failure risks from aging infrastructure and regional connectivity bottlenecks. Through dual-dataset validation using both the Baltimore road network and PeMS07 traffic flow data, we first develop a traffic simulation model integrating Dijkstra’s algorithm with capacity-constrained allocation strategies for guiding reconstruction planning for the collapsed Francis Scott Key Bridge. Next, we create a dynamic adaptive public transit optimization model using an entropy weight-TOPSIS decision framework coupled with an improved simulated annealing algorithm (ISA-TS), achieving coordinated suburban–urban network optimization while maintaining 92.3% solution stability under simulated node failure conditions. The framework introduces three key innovations: (1) a dual-layer regional division model combining K-means geographical partitioning with spectral clustering functional zoning; (2) fault-tolerant network topology optimization demonstrated through 1000-epoch Monte Carlo failure simulations; (3) cross-dataset transferability validation showing 15.7% performance variance between Baltimore and PeMS07 environments. Experimental results demonstrate a 28.7% reduction in road network traffic variance (from 42,760 to 32,100), 22.4% improvement in public transit path redundancy, and 30.4–44.6% decrease in regional traffic load variance with minimal costs. Hyperparameter analysis reveals two optimal operational modes: rapid cooling (rate = 0.90) achieves 85% improvement within 50 epochs for emergency response, while slow cooling (rate = 0.99) yields 12.7% superior solutions for long-term planning. The framework establishes a new multi-objective paradigm balancing structural resilience, functional connectivity, and computational robustness for sustainable smart city transportation systems. Full article

In this study, landslide risk assessment was conducted in the Renhe District, Panzhihua City, China. Firstly, based on 190 landslide points and 10 influencing factors, the landslide hazard was assessed using three models: random forest (RF), eXtreme Gradient Boosting (XGBoost), and Tabular Prior-data Fitted Network (TabPFN). The results indicate that the RF and XGBoost models exhibit comparable performance, both demonstrating strong generalization and accuracy, with the RF model achieving superior generalization, as evidenced by an area-under-the-curve (AUC) value of 0.9471. While the AUC value of TabPFN is 0.9243, indicating higher accuracy, it also poses a risk of overfitting and is therefore more suitable for applications involving small sample sizes and the need for rapid responses. The vulnerability assessment utilized the Analytic Hierarchy Process (AHP) to determine the weights of four disaster-bearing bodies, with sensitivity analysis revealing that road type was the most sensitive vulnerability factor. Finally, the landslide risk-assessment map of the Renhe District was produced by integrating the landslide hazard assessment map with the vulnerability assessment map. The findings indicate that the high-risk zones comprised 2.08% of the research region, which includes three principal train stations and necessitates enhanced protective measures. The medium-risk zones comprise 34.23% of the total area and are scattered throughout the region. It is important to enhance local capabilities for landslide monitoring and early warning systems. Relevant conclusions can provide a significant reference for landslide disaster prevention and mitigation work in the Renhe District and help ensure the safe operation of public transport infrastructure, such as railway stations and airports in the district. Full article