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Receptor-Meditated Endocytosis by Hyaluronic Acid@Superparamagnetic Nanovetor for Targeting of CD44-Overexpressing Tumor Cells
- Kwang Sik Yu,
- Meng Meng Lin,
- Hyun-Ju Lee,
- Ki-Sik Tae,
- Bo-Sun Kang,
- Je Hun Lee,
- Nam Seob Lee,
- Young Gil Jeong,
- Seung-Yun Han and
- Do Kyung Kim
The present report proposes a more rational hyaluronic acid (HA) conjugation protocol that can be used to modify the surface of the superparamagnetic iron oxide nanoparticles (SPIONs) by covalently binding the targeting molecules (HA) with glutamic a...