Search Results (1,868)

Optimization has always been viewed as a central component of many electrical engineering techniques, where it involves designing a complex system with various constraints and competing objectives. The method described in this work proposes a hybrid quantum–classical evolutionary optimization algorithm targeting high-frequency electromagnetic problems. A genetic algorithm with a quantum selection operator that applies high selection pressure while preserving selection diversity is introduced. This change means that stagnation can be reduced without compromising the speed of convergence. This was used on both real quantum hardware as well as quantum simulators. The results demonstrate that the performance of the real quantum devices was deteriorated by the noise in these devices and that simulators would be a useful option. We provide a description of the operation of the proposed evolutionary optimization method with mathematical benchmarks and electromagnetic design problems that show that it outperforms conventional evolutionary algorithms in terms of convergence behavior and robustness. Full article

We present a numerical investigation comparing two entanglement generation protocols in finite XX spin chains with varying spin magnitudes ($s=1/2,1,3/2$). Protocol 1 (P1) relies on staggered couplings to steer correlations toward the ends of the chain. At the same time, Protocol 2 (P2) adopts a dual-port architecture that uses optimized boundary fields to mediate virtual excitations between terminal spins. Our results show that P2 consistently outperforms P1 in all spin values, generating higher-fidelity entanglement in shorter timescales when evaluated under the same system parameters. Furthermore, P2 exhibits superior robustness under realistic imperfections, including diagonal and off-diagonal disorder, as well as dephasing noise. To further assess the resilience of both protocols in experimentally relevant settings, we employ the pseudomode formalism to characterize the impact of non-Markovian noise on the entanglement dynamics. Our analysis reveals that the dual-port mechanism (P2) remains effective even when memory effects are present, as it reduces the excitation of bulk modes that would otherwise enhance environment-induced backflow. Together, the scalability, efficiency, and noise resilience of the dual-port approach position it as a promising framework for entanglement distribution in solid-state quantum information platforms. Full article

Mn²⁺-doped phosphors emitting green light have garnered significant interest due to their potential applications in display technologies and solid-state lighting. To facilitate the rapid synthesis of high-performance Mn²⁺-activated green phosphors, this research optimizes a microwave-assisted solid-state (MASS) method for the preparation of Na₂ZnGeO₄:Mn²⁺. Leveraging the unique attributes of the MASS technique, a systematic investigation into the applicability of various Mn-source precursors was conducted. Additionally, the integration of the MASS approach with traditional solid-state reaction (SSR) methods was assessed. The findings indicate that the MASS technique effectively incorporates Mn ions from diverse precursors (including higher oxidation states of manganese) into the crystal lattice, resulting in efficient green emission from Mn²⁺. Notably, the photoluminescence quantum yield (PLQY) of the sample utilizing MnCO₃ as the manganese precursor was recorded at 2.67%, whereas the sample synthesized from MnO₂ exhibited a remarkable PLQY of 17.69%. Moreover, the post-treatment of SSR-derived samples through the MASS process significantly enhanced the PLQY from 0.67% to 8.66%. These results underscore the promise of the MASS method as a novel and efficient synthesis strategy for the rapid and scalable production of Mn²⁺-doped green luminescent materials. Full article

Preserving quantum entanglement in multipartite systems under environmental decoherence is a critical challenge for quantum information processing. In this work, we investigate the dynamics of W-type entanglement in a system of three photons, focusing on the effects of Markovian and non-Markovian decoherence regimes. Using the lower bound of concurrence (LBC) as a measure of entanglement, we analyze the time evolution of the LBC for photons initially prepared in a W state under the influence of dephasing noise. We explore the dependence of entanglement dynamics on system parameters such as the dephasing angle and refractive-index difference, alongside environmental spectral properties. Our results, obtained within experimentally feasible parameter ranges, reveal how the enhancement of entanglement preservation can be achieved in Markovian and non-Markovian regimes according to the system parameters. These findings provide valuable insights into the robustness of W-state entanglement in tripartite photonic systems and offer practical guidance for optimizing quantum protocols in noisy environments. Full article

We propose an amplitude encoding of the traveling salesperson problem along with a method for calculating the cost function using a probability distribution obtained on a quantum computer. Our encoding requires a number of qubits that grows logarithmically with the number of cities. We propose to calculate the cost function using a nonlinear function of expectation values of quantum operators. This is in contrast to the typical method of evaluating the cost function by summing expectation values of quantum operators. We demonstrate our method using a variational quantum eigensolver algorithm to find the shortest route for a given graph. We find that there is a broad range in the hyperparameters of the optimization procedure for which the best route is found. Full article

Quantum memory is essential for the prolonged storage and retrieval of quantum information. Nevertheless, no current studies have focused on the creation of effective quantum memory for continuous variables while accounting for the decoherence rate. This work presents an effective continuous-variable quantum key distribution method with parameter optimization utilizing the Elitist Elk Herd Random Immigrants Optimizer (2E-HRIO) technique. At the outset of transmission, the quantum device undergoes initialization and authentication via Compressed Hash-based Message Authentication Code with Encoded Post-Quantum Hash (CHMAC-EPQH). The settings are subsequently optimized from the authenticated device via 2E-HRIO, which mitigates the effects of decoherence by adaptively tuning system parameters. Subsequently, quantum bits are produced from the verified device, and pilot insertion is executed within the quantum bits. The pilot-inserted signal is thereafter subjected to pulse shaping using a Gaussian filter. The pulse-shaped signal undergoes modulation. Authenticated post-modulation, the prediction of link failure is conducted through an authenticated channel using Radial Density-Based Spatial Clustering of Applications with Noise. Subsequently, transmission occurs via a non-failure connection. The receiver performs channel equalization on the received signal with Recursive Regularized Least Mean Squares. Subsequently, a dataset for side-channel attack authentication is gathered and preprocessed, followed by feature extraction and classification using Adaptive Depthwise Separable Convolutional Neural Networks (ADS-CNNs), which enhances security against side-channel attacks. The quantum state is evaluated based on the signal received, and raw data are collected. Thereafter, a connection is established between the transmitter and receiver. Both the transmitter and receiver perform the scanning process. Thereafter, the calculation and correction of the error rate are performed based on the sifting results. Ultimately, privacy amplification and key authentication are performed using the repaired key via B-CHMAC-EPQH. The proposed system demonstrated improved resistance to decoherence and side-channel attacks, while achieving a reconciliation efficiency above 90% and increased key generation rate. Full article

Cancer remains one of the most formidable challenges to human health; hence, developing effective treatments is critical for saving lives. An important strategy involves reactivating tumor suppressor genes, particularly p53, by targeting their negative regulator MDM2, which is essential in promoting cell cycle arrest and apoptosis. Leveraging a drug repurposing approach, we screened over 24,000 clinically tested molecules to identify new MDM2 inhibitors. A key innovation of this work is the development and application of a selective cleaning algorithm that systematically filters assay data to mitigate noise and inconsistencies inherent in large-scale bioactivity datasets. This approach significantly improved the predictive accuracy of our machine learning model for pIC₅₀ values, reducing RMSE by 21.6% and achieving state-of-the-art performance (R² = 0.87)—a substantial improvement over standard data preprocessing pipelines. The optimized model was integrated with structure-based virtual screening via molecular docking to prioritize repurposing candidate compounds. We identified two clinical CB1 antagonists, MePPEP and otenabant, and the statin drug atorvastatin as promising repurposing candidates based on their high predicted potency and binding affinity toward MDM2. Interactions with the related proteins MDM4 and BCL2 suggest these compounds may enhance p53 restoration through multi-target mechanisms. Quantum mechanical (ONIOM) optimizations and molecular dynamics simulations confirmed the stability and favorable interaction profiles of the selected protein–ligand complexes, resembling that of navtemadlin, a known MDM2 inhibitor. This multiscale, accuracy-boosted workflow introduces a novel data-curation strategy that substantially enhances AI model performance and enables efficient drug repurposing against challenging cancer targets. Full article

A novel interfacial coating agent was developed by modifying silicone oil with polycyclic aromatic hydrocarbons (PAHs) to enhance the insulation performance of HVDC cable accessories. This study investigates the effects of corona and hot–cold cycle aging on the DC breakdown characteristics of the Cross-Linked Poly Ethylene and Ethylene Propylene Diene Monomer (XLPE/EPDM) interface. Interfacial breakdown tests, infrared spectroscopy, and a microstructural analysis were employed to investigate aging mechanisms. The results show that PAH-modified silicone oil significantly increases the breakdown voltage, with 2,4-dihydroxybenzophenone (C₁₃H₁₀O₃) identified as the optimal additive via quantum chemical calculations (QCCs). Even after aging, the modified interface maintains its superior performance, confirming the long-term reliability of the coating. Full article

The deamidation rate is relatively high for Asn residues with Phe as the C-terminal adjacent residue in γS-crystallin, which is one of the human crystalline lens proteins. However, peptide-based experiments indicated that bulky amino acid residues on the C-terminal side impaired Asn deamination. In this study, we hypothesized that the side chain of Phe affects the Asn deamidation rate and investigated the succinimide formation process using quantum chemical calculations. The B3LYP density functional theory was used to obtain optimized geometries of energy minima and transition states, and MP2 and M06-2X calculations were used to obtain the single-point energy. Activation barriers and rate-determining step changed depending on the orientation of the Phe side chain. In pathways where an interaction occurred between the benzene ring and the amide group of the Asn residue, the activation barrier was lower than in pathways where this interaction did not occur. Since the aromatic ring is oriented toward the Asn side in experimentally determined structures of γS-crystallin, the above interaction is considered to enhance the Asn deamidation. Full article

Quantum-dot cellular automata (QCA) offer a high-performance, low-power alternative to traditional VLSI technology for nanocomputing. However, the existing metal-dot QCA-based parity generators and checker circuits suffer from increased energy dissipation, larger area consumption, and complex multilayered layouts, limiting their practical feasibility. This work designs a 3-bit parity generator and 4-bit checker to address these challenges using an optimized modified majority voter-based Ex-OR gate in QCA. A single-layered layout was simulated in QCADesigner 2.0.3, avoiding crossovers to reduce fabrication complexity. Energy analysis using QCADesigner-E reveals 34.4 meV energy consumption, achieving 31% energy efficiency and 75% area efficiency in the context of QCA costs compared to recent designs. The proposed circuit highlights the unique potential of QCA as a scalable, energy-efficient solution for high-density next-generation computing systems. Full article

This paper starts with an updated review and analyzes recent developments in quantum-inspired algorithms for cybersecurity, with specific attention to possible perspectives of optimization. The enhancement of classical computing capabilities with quantum principles is transforming fields such as machine learning, optimization, and cybersecurity. Evolutionary algorithms are one example where progress has already been made using quantum techniques through increased efficiency, generalization, and problem-solving techniques exploited by quantum principles. Quantum-inspired evolutionary algorithms (QIEAs) and quantum kernel methods are prime examples of such approaches. Quantum techniques are also used in the field of cybersecurity: QML-based identification systems for intrusion detection strengthen threat detection and encoding through quantum techniques with advanced cryptographic security, while quantum-secure hashing (QSHA) offers sophisticated means of protecting sensitive information. More specifically, QGANs are known for their integration into adversarial generative networks that increase efficiency by replacing classical models in adversarial defense through the generation of synthetic attack models. In this work, a set of benchmarks is provided for comparison with classical and other quantum-inspired technologies. The results demonstrate that these methods far outperform others in terms of computational efficiency and satisfactory scalability. Although fully functional models are still awaited, quantum computing benefits greatly from quantum-inspired technologies, as the latter enable the development of frameworks that bring us closer to the quantum era. Consequently, the work takes the form of an updated systematic review enriched with optimized perspectives. Full article

The concept of Nash equilibria in pure strategies for quantum extensions of the general form of the Prisoner’s Dilemma game is investigated. The process of quantization involves incorporating two additional unitary strategies, which effectively expand the classical game. We consider five classes of such quantum games, which remain invariant under isomorphic transformations of the classical game. The resulting Nash equilibria are found to be more closely aligned with Pareto-optimal solutions than those of the conventional Nash equilibrium outcome of the classical game. Our results demonstrate the complexity and diversity of strategic behavior in the quantum setting, providing new insights into the dynamics of classical decision-making dilemmas. In particular, we provide a detailed characterization of strategy profiles and their corresponding Nash equilibria, thereby extending the understanding of quantum strategies’ impact on traditional game-theoretical problems. Full article

Provable data possession (PDP) is a technique that enables the verification of data integrity in cloud storage without the need to download the data. PDP schemes are generally categorized into public and private verification. Public verification allows third parties to assess the integrity of outsourced data, offering good openness and flexibility, but it may lead to privacy leakage and security risks. In contrast, private verification restricts the auditing capability to the data owner, providing better privacy protection but often resulting in higher verification costs and operational complexity due to limited local resources. Moreover, most existing PDP schemes are based on classical number-theoretic assumptions, making them vulnerable to quantum attacks. To address these challenges, this paper proposes an identity-based PDP with a designated verifier over lattices, utilizing a specially leveled identity-based fully homomorphic signature (IB-FHS) scheme. We provide a formal security proof of the proposed scheme under the small-integer solution (SIS) and learning with errors (LWE) within the random oracle model. Theoretical analysis confirms that the scheme achieves security guarantees while maintaining practical feasibility. Furthermore, simulation-based experiments show that for a 1 MB file and lattice dimension of n = 128, the computation times for core algorithms such as TagGen, GenProof, and CheckProof are approximately 20.76 s, 13.75 s, and 3.33 s, respectively. Compared to existing lattice-based PDP schemes, the proposed scheme introduces additional overhead due to the designated verifier mechanism; however, it achieves a well-balanced optimization among functionality, security, and efficiency. Full article

The increasing deployment of photovoltaic and energy storage systems (ESSs) in modern power grids has highlighted the critical challenge of component degradation, which significantly impacts system efficiency, operational costs, and long-term reliability. Conventional energy dispatch and optimization approaches fail to adequately mitigate the progressive efficiency loss in PV modules and battery storage, leading to suboptimal performance and reduced system longevity. To address these challenges, this paper proposes a quantum-enhanced degradation pathway optimization framework that dynamically adjusts operational strategies to extend the lifespan of PV storage systems while maintaining high efficiency. By leveraging quantum-assisted Monte Carlo simulations and hybrid quantum–classical optimization, the proposed model evaluates degradation pathways in real time and proactively optimizes energy dispatch to minimize efficiency losses due to aging effects. The framework integrates a quantum-inspired predictive maintenance algorithm, which utilizes probabilistic modeling to forecast degradation states and dynamically adjust charge–discharge cycles in storage systems. Unlike conventional optimization methods, which struggle with the complexity and stochastic nature of degradation mechanisms, the proposed approach capitalizes on quantum parallelism to assess multiple degradation scenarios simultaneously, significantly enhancing computational efficiency. A three-layer hierarchical optimization structure is introduced, ensuring real-time degradation risk assessment, periodic dispatch optimization, and long-term predictive adjustments based on PV and battery aging trends. The framework is tested on a 5 MW PV array coupled with a 2.5 MWh lithium-ion battery system, with real-world degradation models applied to reflect light-induced PV degradation (0.7% annual efficiency loss) and battery state-of-health deterioration (1.2% per 100 cycles). A hybrid quantum–classical computing environment, utilizing D-Wave’s Advantage quantum annealer alongside a classical reinforcement learning-based optimization engine, enables large-scale scenario evaluation and real-time operational adjustments. The simulation results demonstrate that the quantum-enhanced degradation optimization framework significantly reduces efficiency losses, extending the PV module’s lifespan by approximately 2.5 years and reducing battery-degradation-induced wear by 25% compared to conventional methods. The quantum-assisted predictive maintenance model ensures optimal dispatch strategies that balance energy demand with system longevity, preventing excessive degradation while maintaining grid reliability. The findings establish a novel paradigm in degradation-aware energy optimization, showcasing the potential of quantum computing in enhancing the sustainability and resilience of PV storage systems. This research paves the way for the broader integration of quantum-based decision-making in renewable energy infrastructure, enabling scalable, high-performance optimization for future energy systems. Full article

Mycotoxins are responsible for a multitude of diseases in both humans and animals, resulting in significant medical and economic burdens worldwide. Conventional detection methods, such as enzyme-linked immunosorbent assay (ELISA), high-performance liquid chromatography (HPLC), and liquid chromatography-tandem mass spectrometry (LC-MS/MS), are highly effective, but they are generally confined to laboratory settings. Consequently, there is a growing demand for point-of-care testing (POCT) solutions that are rapid, sensitive, portable, and cost-effective. Lateral flow assays (LFAs) are a pivotal technology in POCT due to their simplicity, rapidity, and ease of use. This review synthesizes data from 78 peer-reviewed studies published between 2015 and 2024, evaluating advances in nanoparticle-based LFAs for detection of singular or multiplex mycotoxin types. Gold nanoparticles (AuNPs) remain the most widely used, due to their favorable optical and surface chemistry; however, significant progress has also been made with silver nanoparticles (AgNPs), magnetic nanoparticles, quantum dots (QDs), nanozymes, and hybrid nanostructures. The integration of multifunctional nanomaterials has enhanced assay sensitivity, specificity, and operational usability, with innovations including smartphone-based readers, signal amplification strategies, and supplementary technologies such as surface-enhanced Raman spectroscopy (SERS). While most singular LFAs achieved moderate sensitivity (0.001–1 ng/mL), only 6% reached ultra-sensitive detection (<0.001 ng/mL), and no significant improvement was evident over time (ρ = −0.162, p = 0.261). In contrast, multiplex assays demonstrated clear performance gains post-2022 (ρ = −0.357, p = 0.0008), largely driven by system-level optimization and advanced nanomaterials. Importantly, the type of sample matrix (e.g., cereals, dairy, feed) did not significantly influence the analytical sensitivity of singular or multiplex lateral LFAs (Kruskal–Wallis p > 0.05), confirming the matrix-independence of these optimized platforms. While analytical challenges remain for complex targets like fumonisins and deoxynivalenol (DON), ongoing innovations in signal amplification, biorecognition chemistry, and assay standardization are driving LFAs toward becoming reliable, ultra-sensitive, and field-deployable platforms for high-throughput mycotoxin screening in global food safety surveillance. Full article