Search Results (29,038)

Reliable high-precision positioning in railway tunnels is essential for intelligent train operation and safety monitoring, yet GNSS signals are severely degraded by blockage and multipath. This paper proposes a deployment-oriented numerical framework to optimize pseudolite layouts in tunnels by explicitly modeling visibility obstruction and controlling worst-case geometry along the train trajectory. A high-fidelity 3D tunnel–train model is established, in which line-of-sight (LoS) availability is screened under vehicle occlusion and trajectory-level geometric quality is evaluated accordingly. Instead of optimizing only the average PDOP, the proposed framework minimizes the trajectory 90th-percentile PDOP (qPDOP) to suppress tail-risk geometric degradation, while interpreting PDOP as an error amplification factor that directly affects positioning reliability under measurement noise and local multipath. The core contribution is a Voronoi-partition-constrained improved genetic algorithm (IGA) for tunnel pseudolite deployment. Voronoi partitioning enforces segment-wise coverage by requiring at least one pseudolite in each partition cell and avoids clustering-induced blind zones. Meanwhile, the IGA incorporates improved search and constraint-handling mechanisms to satisfy practical engineering requirements, including feasible installation regions, minimum spacing, mounting-face balance (ceiling/side walls), communication range, and continuous satellite visibility. Comparative simulations and ablation studies demonstrate that the proposed method achieves more uniform coverage and significantly improves full-trajectory geometric stability, reducing high-quantile PDOP and mitigating local spikes in occlusion-sensitive sections under cost-constrained sparse deployments. The proposed framework provides a practical and flexible toolchain for designing positioning-oriented pseudolite infrastructures in underground transportation environments. Full article

The CAELESTIS project aims to promote the development and design of innovative aircraft and engine structures through an integrated ecosystem of simulations and digital tools, enabling synergy across all stages of the manufacturing process. The component selected was an Outlet Guide Vane (OGV), a static engine part composed of a central composite section and titanium inserts at both ends, joined in a single manufacturing step. A detailed investigation of the joints between these materials was carried out using surface treatments of different natures to evaluate properties that directly influence the final joint quality. Optical analysis techniques were employed to characterize the morphology, roughness and surface free energy (SFE), complemented by mechanical tests to determine the adhesion and shear strength. All specimens were manufactured using the Resin Transfer Molding (RTM) “one-shot” process. Full article

Background/Objectives: Peritoneal metastasis represents the most frequent and prognostically unfavorable metastatic pattern in gastric cancer, largely due to limited sensitivity of conventional imaging, delayed diagnosis, and insufficient response assessment. The aim of this review is to provide an overview of the current evidence on the diagnosis and treatment of gastric cancer with peritoneal metastases and to address current treatment limitations and options. Methods: This review was designed as a narrative review and is based on an extensive literature search in established databases. Results: Systemic chemotherapy remains the cornerstone of palliative treatment, improving the survival and quality of life compared with the best supportive care; however, outcomes in peritoneally metastatic disease remain poor. Advances in molecularly targeted and immune-based therapies have extended survival in selected patient populations, yet favorable molecular profiles are mainly unknown in peritoneal metastases. Staging laparoscopy and semi-quantitative assessment using the Peritoneal Cancer Index (PCI) are therefore essential for accurate diagnosis, prognostication, and treatment selection. Growing evidence from retrospective studies, multi-institutional cohorts, and selected randomized trials suggests that a multimodal approach—combining systemic therapy with intraperitoneal or bidirectional chemotherapy—may improve survival and quality of life. In carefully selected patients whose primary gastric tumor and peritoneal lesions respond to systemic treatment, complete cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) may further enhance outcomes and, in rare cases, achieve long-term survival. These potential benefits appear to be limited to highly selected patients with a low peritoneal tumor burden (PCI ≤ 6–7), positive cytology, good performance status, controlled extraperitoneal disease, and a high likelihood of achieving complete macroscopic cytoreduction (CC-0). Conclusions: Although the treatment intent in metastatic gastric cancer remains primarily palliative, carefully selected patients with limited peritoneal metastases may benefit from intensified multimodal treatment strategies when managed in specialized centers. Interdisciplinary evaluation, accurate staging, and individualized treatment planning are essential to optimize outcomes in this challenging disease setting. Full article

Tensile and compressive stresses generated during the exploitation of wheel rims can lead to significant failures, posing risks to safety and the environment. Among non-destructive evaluation (NDE) methods, ultrasonic velocity measurement has become widely used for assessing stress states in critical rail vehicle components such as wheel rims. In this study, the relationship between ultrasonic wave velocity and applied compressive stresses in aluminum (EN AW-2011) and austenitic stainless steel (1.4301) specimens is investigated. The methodology integrates ultrasonic time-of-flight (TOF) measurements with controlled mechanical loading up to the elastic limit. The results show that ultrasonic velocity increases with applied compressive stress, with an average change of approximately 40 m/s between unloaded and maximum loading conditions. The material type was identified as the dominant factor, with velocity differences of up to 800 m/s between aluminum and steel, while the applied load contributed changes of approximately 200 m/s. Statistical analysis using Design of Experiments (DOE) and ANOVA confirmed the significance of all main factors (p < 0.0001). The findings demonstrate the sensitivity of ultrasonic velocity to elastic stress states and provide a quantitative basis for the development of reliable in situ ultrasonic stress monitoring systems in rail applications. Full article

Volatile organic compounds (VOCs) are ubiquitous pollutants, and exposure from in utero through childhood may impair neurodevelopment. However, compound-specific risks remain unclear. This systematic review and meta-analysis examined associations between VOC exposure and child neurodevelopmental outcomes. A systematic search of PubMed, Scopus, and Embase was conducted until August 2025, yielding 1213 records. Quality assessment was performed using the Newcastle–Ottawa Scale and risk of bias using the ROBINS-E tool. Pooled odds ratios (ORs) were calculated using random-effects models, with heterogeneity evaluated via I² statistics. Subgroup analyses explored for study design, exposure timing, and country income level. Twenty-eight studies were included in the final analysis. Of the 18 VOCs analyzed, five compounds, propionaldehyde (pooled OR = 1.84; 95% CI 1.19–2.49), styrene (pooled OR = 1.69; 95% CI 1.30–2.21), vinyl chloride (pooled OR = 1.53; 95% CI 1.24–1.89), acrolein (pooled OR = 1.48; 95% CI 1.08–2.04), and trichloroethylene (OR = 1.21; 95% CI 1.04–1.41), demonstrated statistically significant adverse associations with neurodevelopment. Benzene showed borderline significance. Heterogeneity ranged from 0–47%. Subgroup analyses identified significant effect modification for 1,3-butadiene by study design and exposure timing and higher pooled estimates for ethylbenzene in high-income countries. Full article

Softmax is a step in transformer computation during which the internal buffer size grows rapidly because of the use of the exponential function. Softmax is a fundamental yet computationally expensive operation in vision transformer attention, posing significant challenges for deployment on resource-constrained FPGAs (Field Programmable Gate Arrays). Computational precision demands grow at the softmax stage in the attention pipeline mainly because of the use of the exponential function in the softmax computation. This paper proposes a low-precision softmax approximation that combines a truncated Maclaurin-series exponential with input-range clamping to enable efficient hardware realization without sacrificing reconstruction quality. By bounding extreme attention scores that contribute negligibly to final outputs, the proposed method mitigates the instability of low-order polynomial approximations while preserving their hardware efficiency. The approach is first validated in software using SwinIR (Image restoration using the SWIN Transformer) super resolution to ensure reconstruction fidelity and is then analyzed for FPGA deployment. SWINIR is a multi-stage version of other transformers like Deit and Vit, making it a preferred option for testing the reconstruction fidelity of the change for transformers. Experimental results demonstrate that the proposed fourth-order clamped approximation achieves near-reference performance, incurring only 0.15 dB PSNR and 0.0059 SSIM degradation on SwinIR-M, while significantly reducing precision and memory requirements. For the large-sized SWINIR model (SWINIR-L), a PSNR increase with a less than 0.01 SSIM loss is observed, further highlighting the insignificance of extreme values as model size gets bigger. A Horner-form reformulation further improves hardware efficiency by limiting intermediate precision growth. Overall, this work presents a reconstruction-aware and hardware-friendly softmax reformulation that enables practical deployment of vision transformers on small FPGA platforms. This work also uses this contribution to improve the performance of the ViTA accelerator design. We also add bias initialization and a PE loop bound runtime variable to the existing ViTA accelerator design. Full article

Urbanization threatens amphibians through habitat loss and fragmentation. The critically endangered Hynobius yangi, endemic to Korea, faces severe habitat destruction from urban development. No previous study has simultaneously assessed physicochemical habitat quality and larval feeding ecology across restored and alternative wetlands for this species using fecal DNA metabarcoding. We compared 25 H. yangi spawning sites in Sasong New Town through long-term monitoring (April 2021–September 2024; 364 surveys) and fecal DNA metabarcoding (18S V9, COI313, and blocking primers) from 60 larvae. Egg sac abundance showed negative associations with habitat area (r = −0.21), pH (r = −0.23), and conductivity (r = −0.21); however, none retained significance after Bonferroni correction, and each explained only 4–5% of variance, indicating exploratory associations. Associated conditions included area 115.5 ± 16.2 m² (mean ± SE), circularity 44.2 ± 2.4%, pH 7.55 ± 0.10, and conductivity 53.0 ± 2.7 μS/cm. Dietary analysis identified 17 prey taxa. Larvae in alternative areas showed generalist feeding favoring Perlidae and Tubificidae, while restored-area larvae showed specialist patterns dominated by Chironomidae, Nematocera, and Psychodidae. Both habitat types supported H. yangi populations. These preliminary findings suggest that appropriately designed alternative areas may complement traditional restoration, pending multi-site validation. Full article

Application Tracking Systems (ATSs) have evolved significantly since their inception in 1996, transitioning from simple resumérepositories to AI-driven tools with advanced capabilities. While these developments have improved recruitment efficiency, they have also raised important ethical, organizational, and human-rights-related concerns. Bias in machine learning (ML) training data, opaque decision criteria, and excessive reliance on automated judgment may contribute to unfair treatment, reduced transparency, and limited human oversight in hiring processes. This study addresses these challenges by proposing a human-centered approach to ATS-supported recruitment based on a set of Humanization Services. Using a Design Science Research approach, three main artifacts were developed: a Job Requirements Validation Module, a Bias Trigger Removal Module, and a blockchain-supported dual-authorization mechanism for vacancy approval, which requires digital signatures from qualified professionals to approve job postings, ensuring that there are humans that assume responsibility. These components are intended to improve job posting quality, reduce bias-conducive information in applicant data, and strengthen accountability in recruitment workflows. The evaluation provides initial empirical support for the operational feasibility of the proposed approach under the tested conditions. The study therefore contributes a practical and theoretically grounded step toward more transparent, accountable, and human-centered AI-supported recruitment. Full article

Background: Although pre-exposure prophylaxis (PrEP) has demonstrated strong clinical efficacy in preventing HIV infection among men who have sex with men (MSM), real-world utilization remains suboptimal. In South Korea, MSM constitute a major population within the domestic HIV epidemic; however, PrEP uptake has not increased pro-portionally to awareness. This discrepancy has been conceptualized as the “awareness–uptake gap,” reflecting multi-level barriers beyond individual knowledge. Purpose: This integrative review aimed to compare PrEP awareness, acceptance, and utilization among MSM populations in South Korea and international settings, and to identify structural, institutional, and psychosocial determinants contributing to the awaness, uptake gap. The study further sought to derive practical implications for nursing practice and health policy. Methods: An integrative literature review was conducted following Whittemore and Knafl’s five-step methodology and reported in line with PRISMA guidance. Electronic searches were performed in PubMed, Google Scholar, RISS, ScienceON, and DBpia for peer-reviewed studies published between 2015 and 2025 in English or Korean. The final search was completed on 31 January 2026. A total of 5952 records were identified, and 187 studies met the inclusion criteria after screening and duplicate removal. Quality appraisal was conducted using AXIS, Newcastle-Ottawa Scale, RoB 2.0, CASP, and MMAT according to study design, and the findings were synthesized within an environmental–structural–individual framework. Results: The included studies consistently showed that awareness of PrEP exceeded actual uptake. Across settings, the awareness–uptake gap was shaped by policy environment, service accessibility, stigma, privacy concerns, economic burden, institutional complexity, and provider preparedness. Comparative evidence from China, Thailand, Belgium and France, Brazil, and West Africa further suggested that awareness alone did not ensure uptake when service pathways were fragmented, culturally unsafe, or poorly understood. Conclusions: Closing the awareness–uptake gap requires integrated policy and practice strategies that extend beyond cost reduction. Strengthening confidentiality systems, simplifying service pathways, and enhancing provider competency—particularly through nurse-centered PrEP navigation and counseling models—may support more sustainable PrEP expansion among MSM populations in global settings. Full article

The utilization of Artificial Intelligence-Generated Content (AIGC) has attracted widespread attention in video content creation. To generate high-quality videos, this paper presents a controllable multimodal fusion architecture for AIGC-driven short-video production. This architecture employs hierarchical constraint mechanisms and a multimodal attention fusion mechanism to enhance video content coherence and user controllability. Specifically, a scene coherence scheme is first designed to construct graph-based global and transition-level constraints by integrating text descriptions, reference images, and audio features. By leveraging the extracted style vector data, preliminary video clips are then generated through a combination of the cross-modal fusion unit and the spatio-temporal consistency unit. Finally, a fine-grained adjustment mechanism is implemented to ensure logical consistency and stylistic uniformity in the AIGC-generated videos. Experimental results indicate that the proposed architecture improves generation quality, controllability, and cross-segment coherence under the adopted evaluation settings. Full article

Background: Gastric cancer survivors frequently encounter a “care gap” after discharge because of complex postgastrectomy syndromes. We evaluated “WECARE,” a bidirectional digital health platform designed to provide real-time symptom monitoring and multidisciplinary support. The primary goal of this study was to assess the efficacy of the platform by measuring the change in the Korean Quality of Life Questionnaire for Gastric Cancer Survivors (KOQUSS-40) total score over a six-month recovery period. Methods: This nationwide, multicenter pilot randomized controlled trial was conducted by the Korean Quality of Life in Stomach Cancer Patients Study Group (KOQUSS) across nine tertiary centers in Korea. A total of 88 patients who underwent curative gastrectomy were enrolled. Following an initial optimization phase involving 22 patients, the remaining 66 patients were randomized at a 1:1 ratio to the WECARE group or the control group. The WECARE group used a platform integrating the KOQUSS-40 algorithm for structured symptom reporting, real-time feedback on nutrition and exercise, and educational content on meal planning, symptom coping, and recovery. Assessments were performed at baseline and at 1, 3, and 6 months after discharge. Results: The WECARE group showed high feasibility and acceptability, with an adherence rate of 86.7% and an 82% satisfaction rate. At 6 months, the KOQUSS-40 total score (primary endpoint) did not differ significantly between the WECARE and control groups (85.3 ± 1.6 vs. 83.8 ± 1.6, p = 0.603). However, the WECARE group showed a numerically favorable recovery trajectory from the acute postoperative phase. Subgroup analysis revealed a positive trend in reflux symptom management in the WECARE group (p = 0.0856). In addition, more than 77% of users reported that the platform improved their self-management capabilities. Conclusions: The WECARE platform is a feasible and acceptable digital intervention for gastric cancer survivors. Although the primary endpoint was not significantly different, the favorable recovery trajectory, high adherence, and patient engagement support further evaluation in larger studies with longer follow-up and broader healthcare settings. Full article

Pitch-based foam carbon, a novel lightweight material, boasts excellent mechanical and thermoelectric properties, and tantalum film deposition on its surface can further enhance its performance. However, this deposition process often suffers from non-uniform deposition and suboptimal coating quality. To address these issues, this study systematically optimized the furnace structure by tuning pipe diameter, tilt angle, and porous media height. Numerical simulations of 216 models were conducted to evaluate the effects of these parameters on axial velocity, turbulence intensity (quantified by the vortex criterion Q > 1), and reactant concentration uniformity. The results showed that pipe diameters below 70 mm increased the mean axial velocity by 8-fold compared to larger diameters, whereas tilt angles of 15° and porous media heights of 60–80 mm yielded limited velocity enhancements of only 2%. Pipe diameter was identified as the dominant factor governing flow stability, inducing up to a 300% variation in the volume fraction of Q > 1, with minimal turbulence observed at the maximum diameter. In contrast, adjustments to tilt angle and porous media height had weaker effects, altering the Q > 1 volume fraction by 26% and 5%, respectively. Smaller pipe diameter (70–80 mm) also optimized TaCl₅ concentration uniformity; tilt angles between 0° and 30° showed negligible influence, while porous media height exhibited no definitive trend. Guided by the practical priorities of process evaluation, a multi-objective optimization was performed. The globally optimal structural parameters were determined to be a pipe diameter of 70 mm, a tilt angle of 15°, and a porous media height of 60 mm, which comprehensively balance deposition uniformity, process stability, and deposition efficiency. These findings establish pipe diameter as the pivotal factor for deposition homogeneity and provide a reference scheme for the structural design of industrial tantalum deposition furnaces and lay a foundation for subsequent multi-physics coupling studies and experimental validation. Full article

Serious youth violence is a public health issue nationally in the UK and internationally. The Youth Endowment Fund (YEF) was established in March 2019, with a £200 million endowment and a ten-year mandate, with a mission to prevent children and young people from becoming involved in violence. This article gives an overview of YEF’s successes and challenges to date, focusing specifically on the experience of evaluating tertiary interventions. After providing an overview of YEF’s approach to funding and evaluation, the article summarises YEF’s work focused on tertiary prevention, including: work to test interventions already being implemented in the UK; adapting and evaluating evidence-based interventions from other jurisdictions in the UK; innovations in a group approach to carrying out evaluations; and embedding a focus on racial equity in tertiary prevention. Next, the article discusses the design issues involved in high-quality evaluation of tertiary prevention, including the scale required and the processes for obtaining consent from young people to participate in evaluations. The article then documents the many challenges and lessons learned from implementing tertiary prevention evaluations, especially focusing on the recruitment and retention of young people. Finally, the article discusses the lessons and places them in a wider context. Full article

Background: Families caring for children with medical complexity (CMC) face sustained psychosocial demands that may impair health-related quality of life (HRQoL) and mental health. A clear map of how these outcomes are assessed and which factors shape them is needed to guide family-centered care. Methods: We conducted a scoping review following the Joanna Briggs Institute guidelines, and reports were prepared according to the PRISMA guidelines. Searches were conducted in PubMed, CINAHL, and EMBASE (January 2011 to December 2023) to find studies reporting on health-related quality of life (HRQoL) and/or mental health outcomes (anxiety, depression, burden) of family members and/or caregivers of CMC, including operationalization based on complex chronic condition (CCC) classifications, technology dependency, or the Pediatric Medical Complexity Algorithm (PMCA). Two reviewers independently screened records and recorded data, and the findings were synthesized narratively and thematically. Results: Sixty-seven studies met the inclusion criteria and spanned cross-sectional, cohort, case–control, pre–post and qualitative designs across conditions such as epilepsy, congenital heart disease, cerebral palsy, technology dependence and cancer. Common measures were PedsQL™ Family Impact Module, SF-36/12, HADS, Beck inventories and Zarit burden scales. Across the included studies, caregivers, predominantly mothers, frequently reported poorer HRQoL and higher levels of anxiety, depressive symptoms, or burden than comparison groups when these were available. Six recurrent themes emerged: (1) gendered caregiving with disproportionate maternal burden; (2) socio-economic gradients and financing models shaping outcomes; (3) culture, religion and spirituality as coping resources; (4) family and social support buffering distress; (5) school participation and coordinated services potentially reducing burden; and (6) interdependence between caregiver and child outcomes. Conclusions: Heterogeneous CMC definitions, outcome measures, and study designs limited comparability across studies. The mapped evidence suggests that family HRQoL and mental health outcomes are shaped by interacting clinical, social, and contextual factors. These findings may inform more family-centered and equity-oriented approaches to care. Future research should harmonize CMC definitions, standardize outcome measures, and prospectively evaluate multicomponent interventions. Full article

Emergency locator transmitters (ELTs) are key safety systems for post-crash aircraft localization and search-and-rescue operations. In more electric aircraft (MEA), however, their design and operation are increasingly influenced by complex electrical architectures, tighter equipment integration, and more demanding electromagnetic environments. This paper presents a narrative literature review of ELT technology from a MEA-oriented perspective. A practice-oriented narrative approach is adopted, examining ELTs through a dual lens: the evolution of the search and rescue (SAR) ecosystem and the progressive electrification of aircraft systems. The review addresses ELT fundamentals, classifications, operating principles, and interaction with the Cospas-Sarsat infrastructure, and examines the transition from legacy analog beacons to modern 406 MHz digital systems incorporating GNSS positioning, MEOSAR capabilities, second-generation beacon functionalities, and distress tracking features. Particular attention is given to integration challenges in MEA platforms, including autonomous energy supply, battery endurance, power quality disturbances, electromagnetic compatibility, installation robustness, antenna survivability, and certification constraints. The analysis highlights that ELT performance in MEA depends not only on the beacon itself, but also on the coupled interaction among device design, installation conditions, and the electrical environment. Finally, the review outlines research priorities for next-generation ELTs, including improved survivability assessment, energy-aware architectures, integration strategies based on electromagnetic compatibility, and certification-ready solutions compatible with future aircraft platforms. Full article