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19 Results Found

  • Article
  • Open Access
3 Citations
3,499 Views
12 Pages

5 July 2024

To evaluate the efficacy of radiomics features extracted from preoperative high-resolution computed tomography (HRCT) scans in distinguishing benign and malignant pulmonary pure ground-glass nodules (pGGNs), a retrospective study of 395 patients from...

  • Systematic Review
  • Open Access
10 Citations
3,162 Views
13 Pages

The nodule diameter was commonly used to predict the invasiveness of pulmonary adenocarcinomas in pure ground-glass nodules (pGGNs). However, the diagnostic performance and optimal cut-off values were inconsistent. We conducted a meta-analysis to eva...

  • Article
  • Open Access
1,492 Views
15 Pages

Objectives: Deep learning-based artificial intelligence (AI) tools have been gradually used to detect and segment pulmonary nodules in clinical practice. This study aimed to assess the diagnostic performance of quantitative measures derived from a co...

  • Article
  • Open Access
28 Citations
4,467 Views
12 Pages

Predictors of Invasive Adenocarcinomas among Pure Ground-Glass Nodules Less Than 2 cm in Diameter

  • Wen-Chi Hsu,
  • Pei-Ching Huang,
  • Kuang-Tse Pan,
  • Wen-Yu Chuang,
  • Ching-Yang Wu,
  • Ho-Fai Wong,
  • Cheng-Ta Yang and
  • Yung-Liang Wan

5 August 2021

Benign lesions, atypical adenomatous hyperplasia (AAH), and malignancies such as adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), and invasive adenocarcinoma (IA) may feature a pure ground-glass nodule (pGGN) on a thin-slide com...

  • Article
  • Open Access
28 Citations
3,648 Views
11 Pages

Lymphadenectomy is Unnecessary for Pure Ground-Glass Opacity Pulmonary Nodules

  • Yi-Han Lin,
  • Chun-Ku Chen,
  • Chih-Cheng Hsieh,
  • Wen-Hu Hsu,
  • Yu-Chung Wu,
  • Jung-Jyh Hung,
  • Po-Kuei Hsu and
  • Han-Shui Hsu

Background: Lobectomy plus lymph node dissection is the standard treatment of early-stage lung cancer, but the low lymph node metastasis rate with ground-glass opacity (GGO) makes surgeons not perform lymphadenectomy. This study aimed to re-evaluate...

  • Article
  • Open Access
25 Citations
3,713 Views
16 Pages

CT-Based Radiomic Analysis for Preoperative Prediction of Tumor Invasiveness in Lung Adenocarcinoma Presenting as Pure Ground-Glass Nodule

  • Tzu-Ning Kao,
  • Min-Shu Hsieh,
  • Li-Wei Chen,
  • Chi-Fu Jeffrey Yang,
  • Ching-Chia Chuang,
  • Xu-Heng Chiang,
  • Yi-Chang Chen,
  • Yi-Hsuan Lee,
  • Hsao-Hsun Hsu and
  • Chung-Ming Chen
  • + 2 authors

29 November 2022

It remains a challenge to preoperatively forecast whether lung pure ground-glass nodules (pGGNs) have invasive components. We aimed to construct a radiomic model using tumor characteristics to predict the histologic subtype associated with pGGNs. We...

  • Article
  • Open Access
2 Citations
3,765 Views
12 Pages

Background: In addition to the diameters of pulmonary nodules, the number and morphology of blood vessels in pure ground-glass nodules (pGGNs) were closely related to the occurrence of lung cancer. Moreover, the benign and malignant signs of nodules...

  • Review
  • Open Access
10 Citations
3,233 Views
9 Pages

How Bronchoscopic Dye Marking Can Help Minimally Invasive Lung Surgery

  • Matthieu Sarsam,
  • Jean-Marc Baste,
  • Luc Thiberville,
  • Mathieu Salaun and
  • Samy Lachkar

6 June 2022

In the era of increasing availability of high-resolution chest computed tomography, the diagnosis and management of solitary pulmonary nodules (SPNs) has become a common challenging clinical problem. Meanwhile, surgical techniques have improved, and...

  • Article
  • Open Access
1 Citations
1,348 Views
12 Pages

Qualitative and Quantitative Computed Tomography Analyses of Lung Adenocarcinoma for Predicting Spread Through Air Spaces

  • Fumi Kameda,
  • Yoshie Kunihiro,
  • Masahiro Tanabe,
  • Masatoshi Nakashima,
  • Taiga Kobayashi,
  • Toshiki Tanaka,
  • Yoshinobu Hoshii and
  • Katsuyoshi Ito

Background/Objectives: Spread through air spaces (STAS) is defined as the spread of tumor cells into the parenchymal alveolar space beyond the margins of the main tumor, and it is associated with worse clinical outcomes in resected lung adenocarcinom...

  • Article
  • Open Access
33 Citations
6,238 Views
14 Pages

The Use of Artificial Intelligence in the Differentiation of Malignant and Benign Lung Nodules on Computed Tomograms Proven by Surgical Pathology

  • Yung-Liang Wan,
  • Patricia Wanping Wu,
  • Pei-Ching Huang,
  • Pei-Kwei Tsay,
  • Kuang-Tse Pan,
  • Nguyen Ngoc Trang,
  • Wen-Yu Chuang,
  • Ching-Yang Wu and
  • ShihChung Benedict Lo

7 August 2020

The purpose of this work was to evaluate the performance of an existing commercially available artificial intelligence (AI) software system in differentiating malignant and benign lung nodules. The AI tool consisted of a vessel-suppression function a...

  • Article
  • Open Access
6 Citations
2,178 Views
14 Pages

31 January 2023

Objectives: Few studies have explored the use of spectral dual-layer detector-based computed tomography (SDCT) parameters, thymidine kinase-1 (TK1), and tumor abnormal protein (TAP) for the detection of ground-glass nodules (GGNs). Therefore, we aime...

  • Article
  • Open Access
4 Citations
3,152 Views
11 Pages

Solitary Pulmonary Capillary Hemangioma: CT and PET-CT Features with Clinicopathologic Correlation

  • Min Ju Kim,
  • Wonju Hong,
  • Tae Jung Kim,
  • Joungho Han,
  • Yoon-La Choi,
  • Joon Young Choi,
  • Sang Min Lee and
  • Sung Ho Hwang

28 October 2022

The aim of this study was to evaluate the CT and PET-CT features of solitary pulmonary capillary hemangioma (SPCH) with clinicopathologic correlations. This retrospective study included 17 patients with histologically proven SPCH from four tertiary i...

  • Article
  • Open Access
13 Citations
3,260 Views
14 Pages

Clinical and Microbiological Characteristics of Culture-Positive, Influenza-Associated Pulmonary Aspergillosis: A Single-Center Study in Southern Taiwan, 2016–2019

  • Chi-Jung Wu,
  • Cong-Tat Cia,
  • Hsuan-Chen Wang,
  • Chang-Wen Chen,
  • Wei-Chieh Lin,
  • Jen-Chieh Lee,
  • Po-Sheng Chen,
  • Chih-Cheng Hsieh,
  • Wei-Ting Li and
  • Po-Lan Su
  • + 4 authors

4 January 2022

This study delineated the characteristics of 24 (11.2%) culture-positive, influenza-associated pulmonary aspergillosis (IAPA) patients out of 215 patients with severe influenza during 2016–2019 in a medical center in southern Taiwan. Twenty (83...

  • Article
  • Open Access
1,706 Views
9 Pages

Intraoperative Transbronchial Metallic Coil Marking for Small Peripheral Pulmonary Lesions in a Hybrid Operation Room

  • Naoya Kawakita,
  • Hiroaki Toba,
  • Naoki Miyamoto,
  • Shinichi Sakamoto,
  • Hiroyuki Sumitomo,
  • Taihei Takeuchi,
  • Atsushi Morishita,
  • Ayaka Baba,
  • Emi Takehara and
  • Keisuke Fujimoto
  • + 2 authors

1 December 2024

Background/Objectives: Computed tomography (CT)-guided transbronchial metallic coil marking is useful for identifying the locations of small peripheral pulmonary lesions. Even deeply located lesions may be accurately identified and resected with adeq...

  • Article
  • Open Access
904 Views
22 Pages

Malignancy in Ground-Glass Opacity Using Multivariate Regression and Deep Learning Models: A Proof-of-Concept Study

  • Abed Agbarya,
  • Edmond Sabo,
  • Mohammad Sheikh-Ahmad,
  • Leonard Saiegh,
  • Mor Pincas,
  • Miguel Gorenberg,
  • Walid Shalata and
  • Dan Levy Faber

14 November 2025

Background/Objectives: Ground-glass opacity (GGO) refers to areas of increased lung opacity on computed tomography (CT) scans. Distinguishing malignant from benign lesions using CT scans remains significantly challenging. This study aims to compare t...

  • Communication
  • Open Access
1 Citations
2,463 Views
10 Pages

Retrospective Analysis of Subsolid Nodules’ Frequency Using Chest Computed Tomography Detection in an Outpatient Population

  • Ana Paula Zanardo,
  • Vicente Bohrer Brentano,
  • Rafael Domingos Grando,
  • Rafael Ramos Rambo,
  • Felipe Teixeira Hertz,
  • Luis Carlos Anflor Junior,
  • Jonatas Favero Prietto Dos Santos,
  • Gabriela Schneider Galvao and
  • Cristiano Feijo Andrade

9 August 2023

Introduction: The study was designed to evaluate the frequency of detection and the characteristics of subsolid nodules (SSNs) in outpatients’ chest computed tomography (CT) scans from a private hospital in Southern Brazil. Methods: A retrospec...

  • Article
  • Open Access
16 Citations
4,757 Views
17 Pages

Deep-Learning-Based Predictive Imaging Biomarker Model for EGFR Mutation Status in Non-Small Cell Lung Cancer from CT Imaging

  • Abhishek Mahajan,
  • Vatsal Kania,
  • Ujjwal Agarwal,
  • Renuka Ashtekar,
  • Shreya Shukla,
  • Vijay Maruti Patil,
  • Vanita Noronha,
  • Amit Joshi,
  • Nandini Menon and
  • Rajiv Kumar Kaushal
  • + 5 authors

12 March 2024

Purpose: The authors aimed to develop and validate deep-learning-based radiogenomic (DLR) models and radiomic signatures to predict the EGFR mutation in patients with NSCLC, and to assess the semantic and clinical features that can contribute to dete...

  • Article
  • Open Access
1 Citations
2,853 Views
12 Pages

Predicting Invasiveness in Lepidic Pattern Adenocarcinoma of Lung: Analysis of Visual Semantic and Radiomic Features

  • Sean F. Johnson,
  • Seyed Mohammad Hossein Tabatabaei,
  • Grace Hyun J. Kim,
  • Bianca E. Villegas,
  • Matthew Brown,
  • Scott Genshaft,
  • Robert D. Suh,
  • Igor Barjaktarevic,
  • William Dean Wallace and
  • Fereidoun Abtin

18 October 2024

Objectives: To differentiate invasive lepidic predominant adenocarcinoma (iLPA) from adenocarcinoma in situ (AIS)/minimally invasive adenocarcinoma (MIA) of lung utilizing visual semantic and computer-aided detection (CAD)-based texture features on s...

  • Article
  • Open Access
1 Citations
1,616 Views
9 Pages

Clinical Versus Pathological Staging in Patients with Resected Ground Glass Pulmonary Lesions

  • Dan Levy Faber,
  • Abed Agbarya,
  • Andrew Lee,
  • Yael Tsenter,
  • Sonia Schneer,
  • Yulia Robitsky Gelis and
  • Ronen Galili

20 December 2024

Background: A ground glass nodule (GGN) is a radiologically descriptive term for a lung parenchymal area with increased attenuation and preserved bronchial and vascular structures. GGNs are further divided into pure versus subsolid lesions. The diffe...