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Search Results (420)

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14 pages, 433 KiB  
Article
Adaptation and Vulnerability in Chronic Pain: A Study of Profiles Based on Clinical and Psychological Factors
by Juan José Mora-Ascó, Carmen Moret-Tatay, María José Jorques-Infante and María José Beneyto-Arrojo
Eur. J. Investig. Health Psychol. Educ. 2025, 15(9), 168; https://doi.org/10.3390/ejihpe15090168 (registering DOI) - 23 Aug 2025
Abstract
Introduction. Chronic pain (CP) is a multidimensional condition that exerts a considerable impact on individuals’ quality of life and presents a wide range of clinical and psychological expressions. This study sought, firstly, to identify distinct clinical profiles among individuals with CP based on [...] Read more.
Introduction. Chronic pain (CP) is a multidimensional condition that exerts a considerable impact on individuals’ quality of life and presents a wide range of clinical and psychological expressions. This study sought, firstly, to identify distinct clinical profiles among individuals with CP based on clinical indicators, and secondly, to examine the differences in psychological vulnerability and pain-related coping strategies according to the clinical profiles. Methods. A total of 251 adults diagnosed with CP and residing in Spain participated in the study. Participants completed the Purpose in Life Test, the Reflective Functioning Questionnaire, the Interpersonal Needs Questionnaire, the Beck Hopelessness Scale, the Difficulties in Emotion Regulation Scale, and the Pain Coping Questionnaire. A two-step cluster analysis was performed to identify subgroups within the sample, followed by independent samples t-tests to assess psychological differences between clusters. Results. This study identified two clinical profiles among individuals with CP, distinguished by diagnostic delay, disease progression, and functional impact. Cluster 1 exhibited greater functional impairment, lower quality of life, and higher emotional distress (uncertainty, perceived burdensomeness, emotional dysregulation, and hopelessness). In contrast, Cluster 2 showed lower functional impairment, better quality of life, greater use of distraction strategies, and a higher meaning in life. Discussion. These findings suggest that both medical and psychological aspects appear to be associated with each other and may influence the perception, evolution and adaptation to CP. Full article
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16 pages, 268 KiB  
Article
Emotional Intelligence and Adolescents’ Use of Artificial Intelligence: A Parent–Adolescent Study
by Marco Andrea Piombo, Sabina La Grutta, Maria Stella Epifanio, Gaetano Di Napoli and Cinzia Novara
Behav. Sci. 2025, 15(8), 1142; https://doi.org/10.3390/bs15081142 - 21 Aug 2025
Abstract
Artificial Intelligence (AI) profoundly shapes adolescents’ digital experiences, presenting both developmental opportunities and risks related to privacy and psychological well-being. This study investigates first the possible generational gap between adolescents and their parents in AI use and trust, and then the associations between [...] Read more.
Artificial Intelligence (AI) profoundly shapes adolescents’ digital experiences, presenting both developmental opportunities and risks related to privacy and psychological well-being. This study investigates first the possible generational gap between adolescents and their parents in AI use and trust, and then the associations between the Trait Emotional Intelligence (trait EI), parenting styles, perceived social support, and parental involvement on adolescents’ use and trust in AI-based technologies. Participants were 170 adolescents (aged 13–17) and 175 parents from southern Italy, who completed standardized questionnaires assessing parenting styles, Trait Emotional Intelligence (Trait EI), social support, digital literacy, and use and trust in AI. Adolescents used AI more frequently than parents, especially for school- or work-related support and were more likely to seek behavioral advice from AI. They also showed higher trust in AI data security and the quality of behavioral advice than parents. Moreover, greater trait EI and more authoritative (vs. authoritarian) parenting were associated with less frequent AI use and lower use and trust in AI. In 47 matched parent–adolescent dyads, cluster analysis identified Balanced Users (higher trait EI, authoritative parenting, stronger support, cautious AI use) and At-Risk Users (lower trait EI, authoritarian parenting, lower support, heavier and more trusting AI use) Despite no causal inferences can be drawn due to the correlational nature of the data, the results suggested the importance of considering adolescents’ trait EI and authoritative parenting practices in supporting balanced and critical digital engagement, highlighting the concept of a “digital secure base” as essential for navigating the evolving digital landscape. Full article
49 pages, 50264 KiB  
Article
Prediction and Optimization of the Restoration Quality of University Outdoor Spaces: A Data-Driven Study Using Image Semantic Segmentation and Explainable Machine Learning
by Xiaowen Zhuang, Zhenpeng Tang, Shuo Lin and Zheng Ding
Buildings 2025, 15(16), 2936; https://doi.org/10.3390/buildings15162936 - 19 Aug 2025
Viewed by 213
Abstract
Evaluating the restoration quality of university outdoor spaces is often constrained by subjective surveys and manual assessment, limiting scalability and objectivity. This study addresses this gap by applying explainable machine learning to predict restorative quality from campus imagery, enabling large-scale, data-driven evaluation and [...] Read more.
Evaluating the restoration quality of university outdoor spaces is often constrained by subjective surveys and manual assessment, limiting scalability and objectivity. This study addresses this gap by applying explainable machine learning to predict restorative quality from campus imagery, enabling large-scale, data-driven evaluation and capturing complex nonlinear relationships that traditional methods may overlook. Using Fujian Agriculture and Forestry University as a case study, this study extracted road network data, generated 297 coordinates at 50-m intervals, and collected 1197 images. Surveys were conducted to obtain restorative quality scores. The Mask2Former model was used to extract landscape features, and decision tree algorithms (RF, XGBoost, GBR) were selected based on MAE, MSE, and EVS metrics. The combination of optimal algorithms and SHAP was employed to predict restoration quality and identify key features. This research also used a multivariate linear regression model to identify features with significant statistical impact but lower features importance ranking. Finally, the study also analyzed heterogeneity in scores for three restoration indicators and five campus zones using k-means clustering. Empirical results show that natural elements like vegetation and water positively affect psychological perception, while structural components like walls and fences have negative or nonlinear effects. On this basis, this study proposes spatial optimization strategies for different campus areas, offering a foundation for creating high-quality outdoor environments with restorative and social functions. Full article
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18 pages, 2817 KiB  
Article
Phenotyping Fatigue Profiles in Marfan Syndrome Through Cluster Analysis: A Cross-Sectional Study of Psychosocial and Clinical Correlates
by Nathasha Samali Udugampolage, Jacopo Taurino, Alessandro Pini, Edward Callus, Arianna Magon, Gianluca Conte, Giada De Angeli, Miriam Angolani, Giulia Paglione, Irene Baroni, Pasquale Iozzo and Rosario Caruso
J. Clin. Med. 2025, 14(16), 5802; https://doi.org/10.3390/jcm14165802 - 16 Aug 2025
Viewed by 290
Abstract
Background/Objectives: Fatigue is a highly prevalent and burdensome symptom among individuals with Marfan syndrome (MFS), yet its heterogeneity and underlying psychosocial and clinical correlates remain underexplored. This study aimed to identify and characterize distinct fatigue-related profiles in MFS patients using a data-driven [...] Read more.
Background/Objectives: Fatigue is a highly prevalent and burdensome symptom among individuals with Marfan syndrome (MFS), yet its heterogeneity and underlying psychosocial and clinical correlates remain underexplored. This study aimed to identify and characterize distinct fatigue-related profiles in MFS patients using a data-driven cluster analysis approach. Methods: A cross-sectional study was conducted involving 127 patients with MFS from a specialized connective tissue disorder center in Italy. Participants completed self-reported measures of fatigue severity (Fatigue Severity Scale, FSS), depressive symptoms (Patient Health Questionnaire-9, PHQ-9), and insomnia (Insomnia Severity Index, ISI). The body mass index (BMI) and clinical data were also collected. A t-distributed stochastic neighbor embedding (t-SNE) analysis was performed to reduce dimensionality, followed by hierarchical clustering (Ward’s method), exploring solutions from k = 2 to k = 10. The optimal cluster solution was identified based on silhouette scores and clinical interpretability. Results: Three distinct clusters emerged: (1) a cluster characterized by low fatigue with minimal psychological and sleep-related symptoms (younger patients, lower PHQ-9 and ISI scores), (2) a cluster characterized by moderate fatigue with moderate psychological and sleep-related symptoms (intermediate age, moderate PHQ-9 and ISI scores), and (3) a cluster characterized by high fatigue with elevated psychological and sleep-related symptoms (older patients, higher PHQ-9, ISI, and FSS scores). Significant differences were observed across clusters in age, BMI, depressive symptoms, insomnia severity, and fatigue levels (all p < 0.05). Conclusions: Our findings highlight the heterogeneity of fatigue experiences in MFS and suggest the importance of profiling patients to guide personalized interventions. This approach may inform precision medicine strategies and enhance the quality of life for individuals with this rare disease. Full article
(This article belongs to the Section Cardiovascular Medicine)
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31 pages, 1381 KiB  
Article
Exploring Generation Z’s Acceptance of Artificial Intelligence in Higher Education: A TAM and UTAUT-Based PLS-SEM and Cluster Analysis
by Réka Koteczki and Boglárka Eisinger Balassa
Educ. Sci. 2025, 15(8), 1044; https://doi.org/10.3390/educsci15081044 - 14 Aug 2025
Viewed by 321
Abstract
In recent years, the rapid growth of artificial intelligence (AI) has significantly transformed higher education, particularly among Generation Z students who are more open to new technologies. Tools such as ChatGPT are increasingly being used for learning, yet empirical research on their acceptance, [...] Read more.
In recent years, the rapid growth of artificial intelligence (AI) has significantly transformed higher education, particularly among Generation Z students who are more open to new technologies. Tools such as ChatGPT are increasingly being used for learning, yet empirical research on their acceptance, especially in Hungary, is limited. This study aims to explore the psychological, technological, and social factors that influence the acceptance of AI among Hungarian university students and to identify different user groups based on their attitudes. The methodological novelty lies in combining two approaches: partial least-squares structural equation modelling (PLS-SEM) and cluster analysis. The survey, based on the TAM and UTAUT models, involved 302 Hungarian students and examined six dimensions of AI acceptance: perceived usefulness, ease of use, attitude, social influence, enjoyment and behavioural intention. The PLS-SEM results show that enjoyment (β = 0.605) is the strongest predictor of the intention to use AI, followed by usefulness (β = 0.167). All other factors also had significant effects. Cluster analysis revealed four groups: AI sceptics, moderately open users, positive acceptors, and AI innovators. The findings highlight that the acceptance of AI is shaped not only by functionality but also by user experience. Educational institutions should, therefore, provide enjoyable and user-friendly AI tools and tailor support to students’ attitude profiles. Full article
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22 pages, 3599 KiB  
Article
Exploring Artificial Personality Grouping Through Decision Making in Feature Spaces
by Yuan Zhou and Siamak Khatibi
AI 2025, 6(8), 184; https://doi.org/10.3390/ai6080184 - 11 Aug 2025
Viewed by 373
Abstract
Human personality (HP) is seen as an individual’s consistent patterns of feeling, thinking, and behaving by today’s psychological studies, in which HPs are characterized in terms of traits—in particular, as relatively enduring characteristics that influence human behavior across many situations. In this sense, [...] Read more.
Human personality (HP) is seen as an individual’s consistent patterns of feeling, thinking, and behaving by today’s psychological studies, in which HPs are characterized in terms of traits—in particular, as relatively enduring characteristics that influence human behavior across many situations. In this sense, more generally, artificial personality (AP) is studied in computer science to develop AI agents who should behave more like humans. However, in this paper, we suggest another approach by which the APs of individual agents are distinguishable based on their behavioral characteristics in achieving tasks and not necessarily in their human-like performance. As an initial step toward AP, we propose an approach to extract human decision-making characteristics as a generative resource for encoding the variability in agent personality. Using an application example, we demonstrate the feasibility of grouping APs, divided into several steps consisting of (1) defining a feature space to measure the commonality of decision making between individual and a group of people; (2) grouping APs by using multidimensional orthogonal features in the feature space to guarantee inter-individual differences between APs in achieving for the same task; and (3) evaluating the consistency of grouping APs by performing a cluster-stability analysis. Finally, our thoughts for the future implementation of APs are discussed and presented. Full article
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19 pages, 298 KiB  
Review
Speaking the Self: How Native-Language Psychotherapy Enables Change in Refugees: A Person-Centered Perspective
by Viktoriya Zipper-Weber
Healthcare 2025, 13(15), 1920; https://doi.org/10.3390/healthcare13151920 - 6 Aug 2025
Viewed by 369
Abstract
Background: Since the outbreak of war in Ukraine, countless forcibly displaced individuals facing not only material loss, but also deep psychological distress, have sought refuge across Europe. For those traumatized by war, the absence of a shared language in therapy can hinder healing [...] Read more.
Background: Since the outbreak of war in Ukraine, countless forcibly displaced individuals facing not only material loss, but also deep psychological distress, have sought refuge across Europe. For those traumatized by war, the absence of a shared language in therapy can hinder healing and exacerbate suffering. While cultural diversity in psychotherapy has gained recognition, the role of native-language communication—especially from a person-centered perspective—remains underexplored. Methods: This narrative review with a thematic analysis examines whether and how psychotherapy in the mother tongue facilitates access to therapy and enhances therapeutic efficacy. Four inter-related clusters emerged: (1) the psychosocial context of trauma and displacement; (2) language as a structural gatekeeper to care (RQ1); (3) native-language therapy as a mechanism of change (RQ2); (4) potential risks such as over-identification or therapeutic mismatch (RQ2). Results: The findings suggest that native-language therapy can support the symbolic integration of trauma and foster the core conditions for healing. The implications for multilingual therapy formats, training in interpreter-mediated settings, and future research designs—including longitudinal, transnational studies—are discussed. Conclusions: In light of the current crises, language is not just a tool for access to therapy, but a pathway to psychological healing. Full article
(This article belongs to the Special Issue Healthcare for Immigrants and Refugees)
32 pages, 18361 KiB  
Review
Responsive Therapeutic Environments: A Dual-Track Review of the Research Literature and Design Case Studies in Art Therapy for Children with Autism Spectrum Disorder
by Jing Liang, Jingxuan Jiang, Jinghao Hei and Jiaqi Zhang
Buildings 2025, 15(15), 2735; https://doi.org/10.3390/buildings15152735 - 3 Aug 2025
Viewed by 670
Abstract
Art therapy serves as a crucial intervention modality for children with autism spectrum disorder (ASD), demonstrating unique value in emotional expression, sensory integration, and social communication. However, current practice presents critical challenges, including the disconnect between design expertise and clinical needs, unclear mechanisms [...] Read more.
Art therapy serves as a crucial intervention modality for children with autism spectrum disorder (ASD), demonstrating unique value in emotional expression, sensory integration, and social communication. However, current practice presents critical challenges, including the disconnect between design expertise and clinical needs, unclear mechanisms of environmental factors’ impact on therapeutic outcomes, and insufficient evidence-based support for technology integration. Purpose: This study aimed to construct an evidence-based theoretical framework for art therapy environment design for children with autism, clarifying the relationship between environmental design elements and therapeutic effectiveness. Methodology: Based on the Web of Science database, this study employed a dual-track approach comprising bibliometric analysis and micro-qualitative content analysis to systematically examine the knowledge structure and developmental trends. Research hotspots were identified through keyword co-occurrence network analysis using CiteSpace, while 24 representative design cases were analyzed to gain insights into design concepts, emerging technologies, and implementation principles. Key Findings: Through keyword network visualization analysis, this study identified ten primary research clusters that were systematically categorized into four core design elements: sensory feedback design, behavioral guidance design, emotional resonance design, and therapeutic support design. A responsive therapeutic environment conceptual framework was proposed, encompassing four interconnected components based on the ABC model from positive psychology: emotional, sensory, environmental, and behavioral dimensions. Evidence-based design principles were established emphasizing child-centeredness, the promotion of multisensory expression, the achievement of dynamic feedback, and appropriate technology integration. Research Contribution: This research establishes theoretical connections between environmental design elements and art therapy effectiveness, providing a systematic design guidance framework for interdisciplinary teams, including environmental designers, clinical practitioners, technology developers, and healthcare administrators. The framework positions technology as a therapeutic mediator rather than a driver, ensuring technological integration supports rather than interferes with children’s natural creative impulses. This contributes to creating more effective environmental spaces for art therapy activities for children with autism while aligning with SDG3 goals for promoting mental health and reducing inequalities in therapeutic access. Full article
(This article belongs to the Special Issue Art and Design for Healing and Wellness in the Built Environment)
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24 pages, 2839 KiB  
Article
Personality Assessment Inventory in Fibromyalgia: Links to Functional, Physical–Somatic, and Emotional Impact
by Andrea Doreste, Jesus Pujol, Eva Penelo, Víctor Pérez, Laura Blanco-Hinojo, Gerard Martínez-Vilavella, Fabiola Ojeda, Jordi Monfort and Joan Deus
Eur. J. Investig. Health Psychol. Educ. 2025, 15(8), 149; https://doi.org/10.3390/ejihpe15080149 - 1 Aug 2025
Viewed by 409
Abstract
Background: Fibromyalgia (FM) is a chronic condition characterized by widespread pain, fatigue, cognitive difficulties, and psychological symptoms. Patients often present distinct personality traits and psychopathological patterns associated with symptom severity. Objective: To examine psychopathological profiles in FM patients based on functional, physical–somatic, and [...] Read more.
Background: Fibromyalgia (FM) is a chronic condition characterized by widespread pain, fatigue, cognitive difficulties, and psychological symptoms. Patients often present distinct personality traits and psychopathological patterns associated with symptom severity. Objective: To examine psychopathological profiles in FM patients based on functional, physical–somatic, and emotional impairment domains, as well as on cumulative disease severity. Materials and Methods: A cross-sectional study was conducted with 70 women clinically diagnosed with FM at a specialized Fibromyalgia Unit. Psychological functioning was assessed using the Personality Assessment Inventory, and disease impact was measured with the Fibromyalgia Impact Questionnaire. Hierarchical cluster analyses were used to classify participants into mild and severe clusters across FIQ domains, and psychological profiles were compared. Results: Patients with severe functional impairment had more affective dysregulation (76.43 vs. 70.20, p < 0.01) and somatic complaints (85.57 vs. 79.76, p < 0.05) than those with mild impairment. The severe–physical cluster showed greater mood instability, somatization, and suicidal ideation (60.94 vs. 53.61, p < 0.05). The severe–emotional cluster had higher rates of major depression (85.71% vs. 64.28%) and persistent depressive disorder (76.19% vs. 70.61%, p < 0.05). Severe showed more emotional instability and somatization, distinguishing it from mild. Greater cumulative severity intensified depressive and somatic disorders. Discussion: Findings support FM’s biopsychosocial profile, where emotional distress may relate to psychological and physical symptoms, reinforcing the need for personalized, multidisciplinary care and comprehensive assessment. Full article
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24 pages, 3726 KiB  
Article
Telemedicine-Supported CPAP Therapy in Patients with Obstructive Sleep Apnea: Association with Treatment Adherence and Clinical Outcomes
by Norbert Wellmann, Versavia Maria Ancusa, Monica Steluta Marc, Ana Adriana Trusculescu, Camelia Corina Pescaru, Flavia Gabriela Martis, Ioana Ciortea, Alexandru Florian Crisan, Adelina Maritescu, Madalina Alexandra Balica and Ovidiu Fira-Mladinescu
J. Clin. Med. 2025, 14(15), 5339; https://doi.org/10.3390/jcm14155339 - 29 Jul 2025
Viewed by 451
Abstract
Background/Objectives: Obstructive sleep apnea (OSA) is a highly prevalent disorder that significantly impacts quality of life and daily functioning. While continuous positive airway pressure (CPAP) therapy is effective, long-term adherence remains a challenge. This single-arm observational study aimed to evaluate clinical outcomes and [...] Read more.
Background/Objectives: Obstructive sleep apnea (OSA) is a highly prevalent disorder that significantly impacts quality of life and daily functioning. While continuous positive airway pressure (CPAP) therapy is effective, long-term adherence remains a challenge. This single-arm observational study aimed to evaluate clinical outcomes and adherence patterns during telemedicine-supported CPAP therapy and identify distinct phenotypic response clusters in Romanian patients with OSA. Methods: This prospective observational study included 86 adults diagnosed with OSA, treated with ResMed Auto CPAP devices at “Victor Babeș” University Hospital in Timișoara, Romania. All patients were remotely monitored via the AirView™ platform and received monthly telephone interventions to promote adherence when necessary. Clinical outcomes were assessed through objective telemonitoring data. K-means clustering and t-distributed stochastic neighbor embedding (t-SNE) were employed to explore phenotypic response patterns. Results: During telemedicine-supported CPAP therapy, significant clinical improvements were observed. The apnea–hypopnea index (AHI) decreased from 42.0 ± 21.1 to 1.9 ± 1.3 events/hour. CPAP adherence improved from 75.5% to 90.5% over six months. Average daily usage increased from 348.4 ± 85.8 to 384.2 ± 65.2 min. However, post hoc analysis revealed significant concerns about the validity of self-reported psychological improvements. Self-esteem changes showed negligible correlation with objective clinical measures (r < 0.2, all p > 0.1), with only 3.3% of variance being explained by measurable therapeutic factors (R2 = 0.033). Clustering analysis identified four distinct adherence and outcome profiles, yet paradoxically, patients with lower adherence showed greater self-esteem improvements, contradicting therapeutic causation. Conclusions: Telemedicine-supported CPAP therapy with structured monthly interventions was associated with substantial clinical improvements, including excellent AHI reduction (22-fold) and high adherence rates (+15% after 6 months). Data-driven phenotyping successfully identified distinct patient response profiles, supporting personalized management approaches. However, the single-arm design prevents definitive attribution of improvements to telemonitoring versus natural adaptation or placebo effects. Self-reported psychological outcomes showed concerning patterns suggesting predominant placebo responses rather than therapeutic benefits. While the overall findings demonstrate the potential value of structured telemonitoring for objective CPAP outcomes, controlled trials are essential to establishing true therapeutic efficacy and distinguishing intervention effects from measurement bias. Full article
(This article belongs to the Special Issue Advances in Pulmonary Disease Management and Innovation in Treatment)
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26 pages, 3526 KiB  
Article
All Roads Lead to Excellence: A Comparative Scientometric Assessment of French and Dutch European Research Council Grant Winners’ Academic Performance in the Domain of Social Sciences and Humanities
by Gergely Ferenc Lendvai, Petra Aczél and Péter Sasvári
Publications 2025, 13(3), 34; https://doi.org/10.3390/publications13030034 - 24 Jul 2025
Viewed by 647
Abstract
This study investigates how differing national research governance models impact academic performance by comparing European Research Council (ERC) grant winners in the social sciences and humanities from France and the Netherlands. Situated within the broader context of centralized versus decentralized research systems, the [...] Read more.
This study investigates how differing national research governance models impact academic performance by comparing European Research Council (ERC) grant winners in the social sciences and humanities from France and the Netherlands. Situated within the broader context of centralized versus decentralized research systems, the analysis aims to understand how these structures shape publication trends, thematic diversity, and collaboration patterns. Drawing on Scopus and SciVal data covering 9996 publications by 305 ERC winners between 2019 and 2023, we employed a multi-method approach, including latent Dirichlet allocation for topic modeling, compound annual growth rate analysis, and co-authorship network analysis. The results show that neuroscience, climate change, and psychology are dominant domains, with language and linguistics particularly prevalent in France and law and political science in the Netherlands. French ERC winners are more likely to be affiliated with national or sectoral institutions, whereas in the Netherlands, elite universities dominate. Collaboration emerged as a key success factor, with an average of four co-authors per publication and network analyses revealing central figures who bridge topical clusters. International collaborations were consistently linked with higher visibility, while single-authored publications showed limited impact. These findings suggest that institutional context and collaborative practices significantly shape research performance in both countries. Full article
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17 pages, 893 KiB  
Article
How Do Information Interventions Influence Walking and Cycling Behavior?
by Wenxuan Lu, Lan Wu, Chaoying Yin, Ming Yang, Qiyuan Yang and Xiaoyi Zhang
Buildings 2025, 15(15), 2602; https://doi.org/10.3390/buildings15152602 - 23 Jul 2025
Viewed by 310
Abstract
In the context of promoting sustainable mobility, walking and cycling have been widely recognized for their environmental and health benefits. However, a notable gap often exists between residents’ motivation to engage in these modes and their actual behavior. This study focuses on this [...] Read more.
In the context of promoting sustainable mobility, walking and cycling have been widely recognized for their environmental and health benefits. However, a notable gap often exists between residents’ motivation to engage in these modes and their actual behavior. This study focuses on this motivation–behavior discrepancy and explores how heterogeneous information interventions—within the constraints of the existing built environment—can effectively influence residents’ travel psychology and behavior. Drawing on Protection Motivation Theory, this study aims to uncover the psychological mechanisms behind travel-mode choices and quantify the relative impacts of different types of information interventions. A travel survey was conducted in Yangzhou, China, collecting data from 1052 residents. Cluster analysis was performed using travel psychology data to categorize travel motivations and examine their alignment with actual travel behavior. A random forest model was then employed to assess the effects of individual attributes, travel characteristics, and information intervention attributes on the choice of walking and cycling. The results reveal a significant motivation–behavior gap: while 76% of surveyed residents expressed motivation to walk or cycle, only 30% actually adopted these modes. Based on this, further research shows that informational attributes exhibit a stronger effect in terms of promoting walking and cycling behavior compared to individual attributes and travel characteristics. Among these, health-related information demonstrates the maximum efficacy in areas with well-developed infrastructure. Specifically, health-related information has a greater impact on cycling (21.4%), while environmental information exerts a stronger influence on walking (7.31%). These findings suggest that leveraging information to promote walking and cycling should be more targeted. Full article
(This article belongs to the Special Issue New Trends in Built Environment and Mobility)
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11 pages, 452 KiB  
Review
Lysergic Acid Amide (LSA), an LSD Analog: Systematic Review of Pharmacological Effects, Adverse Outcomes, and Therapeutic Potentials
by Paula S. C. C. Castro, Kae Leopoldo, Maria Olivia Pozzolo Pedro, Juliana Takitane, Henrique Silva Bombana, André Brooking Negrão, Jaqueline R. Scholz and João Maurício Castaldelli-Maia
Pharmacy 2025, 13(4), 98; https://doi.org/10.3390/pharmacy13040098 - 21 Jul 2025
Viewed by 1650
Abstract
Objective: To systematically review the scientific literature on lysergic acid amide (LSA), focusing on its physical, neurobiological, and social effects, as well as its potential risks and therapeutic uses. Methods: A systematic review was conducted across PubMed, Google Scholar, and Web [...] Read more.
Objective: To systematically review the scientific literature on lysergic acid amide (LSA), focusing on its physical, neurobiological, and social effects, as well as its potential risks and therapeutic uses. Methods: A systematic review was conducted across PubMed, Google Scholar, and Web of Science up to December 2023, using keywords such as “ergine,” “lysergic acid amide,” and “legal high.” Studies were included if they reported original human data on the physical, neurobiological, psychological, or social effects of LSA; seventeen studies were included. Animal studies, in vitro research, and non-original articles were excluded. Two independent reviewers screened and selected the studies, with a third resolving discrepancies. Data were extracted using a standardized form. The review followed PRISMA guidelines and was prospectively registered on the Open Science Framework. Results: LSA is primarily consumed through preparations made from the seeds of Convolvulaceae plants. Reported effects include euphoria, hallucinations, nausea, and anxiety. Severe adverse outcomes, such as psychosis, hypertension, and hospitalization, have also been documented. Some evidence suggests its potential therapeutic application for cluster headaches. However, variability in dosing and misinformation on digital platforms heighten the risks associated with LSA use. Conclusions: LSA poses significant health risks, exacerbated by online misinformation and variability in its effects, and a lack of scientific studies. Further research is essential to clarify its pharmacological profile, establish guidelines for safe use, and raise public awareness about its dangers. Full article
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27 pages, 4187 KiB  
Article
Assessing Occupational Work-Related Stress and Anxiety of Healthcare Staff During COVID-19 Using Fuzzy Natural Language-Based Association Rule Mining
by Abdulaziz S. Alkabaa, Osman Taylan, Hanan S. Alqabbaa and Bulent Guloglu
Healthcare 2025, 13(14), 1745; https://doi.org/10.3390/healthcare13141745 - 18 Jul 2025
Viewed by 333
Abstract
Background/Objective: Frontline healthcare staff who contend diseases and mitigate their transmission were repeatedly exposed to high-risk conditions during the COVID-19 pandemic. They were at risk of mental health issues, in particular, psychological stress, depression, anxiety, financial stress, and/or burnout. This study aimed to [...] Read more.
Background/Objective: Frontline healthcare staff who contend diseases and mitigate their transmission were repeatedly exposed to high-risk conditions during the COVID-19 pandemic. They were at risk of mental health issues, in particular, psychological stress, depression, anxiety, financial stress, and/or burnout. This study aimed to investigate and evaluate the occupational stress of medical doctors, nurses, pharmacists, physiotherapists, and other hospital support crew during the COVID-19 pandemic in Saudi Arabia. Methods: We collected both qualitative and quantitative data from a survey given to public and private hospitals using methods like correspondence analysis, cluster analysis, and structural equation models to investigate the work-related stress (WRS) and anxiety of the staff. Since health-related factors are unclear and uncertain, a fuzzy association rule mining (FARM) method was created to address these problems and find out the levels of work-related stress (WRS) and anxiety. The statistical results and K-means clustering method were used to find the best number of fuzzy rules and the level of fuzziness in clusters to create the FARM approach and to predict the work-related stress and anxiety of healthcare staff. This innovative approach allows for a more nuanced appraisal of the factors contributing to work-related stress and anxiety, ultimately enabling healthcare organizations to implement targeted interventions. By leveraging these insights, management can foster a healthier work environment that supports staff well-being and enhances overall productivity. This study also aimed to identify the relevant health factors that are the root causes of work-related stress and anxiety to facilitate better preparation and motivation of the staff for reorganizing resources and equipment. Results: The results and findings show that when the financial burden (FIN) of healthcare staff increased, WRS and anxiety increased. Similarly, a rise in psychological stress caused an increase in WRS and anxiety. The psychological impact (PCG) ratio and financial impact (FIN) were the most influential factors for the staff’s anxiety. The FARM results and findings revealed that improving the financial situation of healthcare staff alone was not sufficient during the COVID-19 pandemic. Conclusions: This study found that while the impact of PCG was significant, its combined effect with FIN was more influential on staff’s work-related stress and anxiety. This difference was due to the mutual effects of PCG and FIN on the staff’s motivation. The findings will help healthcare managers make decisions to reduce or eliminate the WRS and anxiety experienced by healthcare staff in the future. Full article
(This article belongs to the Special Issue Depression, Anxiety and Emotional Problems Among Healthcare Workers)
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35 pages, 1200 KiB  
Systematic Review
The Social Side of Biodiversity Loss: A Review of Individual, Collective, and Structural Drivers in Coastal Regions
by Alexander Yendell, Yvonne Jaeckel, Giulia Bär and Helene Lerch
Sustainability 2025, 17(14), 6547; https://doi.org/10.3390/su17146547 - 17 Jul 2025
Viewed by 1210
Abstract
This literature review investigates how social, cultural, political, and psychological factors contribute to biodiversity loss in coastal ecosystems. While biodiversity decline is often analyzed from ecological or economic perspectives, this review focuses on the societal dimensions that shape environmental attitudes and behaviors. Using [...] Read more.
This literature review investigates how social, cultural, political, and psychological factors contribute to biodiversity loss in coastal ecosystems. While biodiversity decline is often analyzed from ecological or economic perspectives, this review focuses on the societal dimensions that shape environmental attitudes and behaviors. Using a semi-structured approach, we searched Web of Science, Scopus, and Google Scholar for peer-reviewed studies that address social influences on biodiversity, particularly in coastal contexts. Boolean logic and targeted keywords guided the selection, complemented by snowballing techniques to identify additional relevant literature. From over 600 initial results, 57 studies were included in the final synthesis. The literature spans diverse disciplines, including sociology, political science, environmental psychology, and cultural studies. Although many studies do not explicitly focus on coastal areas, they provide transferable insights into conservation-related behavior and structural drivers of biodiversity pressure. The review identifies thematic clusters and theoretical gaps, particularly regarding underexplored social variables and insufficient attention to multi-level dynamics. Our findings underline the need for stronger integration of societal dimensions into biodiversity research and policy, especially in coastal regions facing complex socio-ecological challenges. Full article
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