Search Results (5,839)

With the construction of transportation networks in mountainous areas under the Western Development Strategy, double-row pile foundations on slopes have been widely applied. However, due to the distortion of the soil stress field, their load distribution mechanism under bidirectional loading is extremely complex. To investigate the internal force distribution laws and deformation and failure modes, a systematic study was conducted utilizing theoretical derivation: 60 scale indoor physical model tests, and 3D refined finite element numerical simulations. The results show that the force distribution of double-row piles in slope environments differs significantly: the upper-row piles, affected by active earth pressure and sliding thrust, bear significantly higher load than the lower-row piles; meanwhile, the lower-row piles, constrained by stronger deep soil, can more fully utilize their vertical bearing capacity. Parametric analysis indicates that the terrain slope has a nonlinear amplification effect on the displacement difference at the pile top, with 50° being the critical mutation slope that triggers the failure of connection joints. In addition, the deformation mode of double-row piles undergoes a change when the pile spacing exceeds 5 times the pile diameter. Therefore, in practical engineering design, the traditional concept of symmetrical reinforcement should be abandoned in favor of differentiated bending reinforcement targeting the shallow surface layer of the upper-row piles and the deep inflection point of the lower-row piles. For working conditions with a slope greater than 50°, additional measures such as prestressed anchor cables must be applied to reduce the sliding load. Meanwhile, the row spacing should be strictly controlled within 5 times the pile diameter to fully ensure the diaphragm effect and the overall synergistic stability of the structure. Full article

Objectives: This study investigated the interplay between pre- and post-match physiological responses and subsequent emotional changes in male water polo players competing in the Italian Serie C league (third national level, sub-elite), focusing on differences between official championship (competitive) and non-competitive (training) settings. Methods: Sixteen male Italian Serie C water polo players participated. Salivary biomarkers (cortisol, immunoglobulin A (IgA), and uric acid) were measured, alongside psychological assessments of cognitive anxiety, somatic anxiety, and self-confidence. Measurements were taken before and after both training and competition matches. Results: A significant anticipatory rise in salivary cortisol was observed before competition matches compared to training, highlighting the psychological stress associated with competitive events. Post-match, cortisol levels remained elevated to a greater extent after competition. Salivary IgA levels decreased significantly following both training and competition, with a more pronounced reduction after official matches, and exhibited a negative correlation with cortisol. Salivary uric acid, a marker of oxidative stress, increased post-exercise and was significantly higher after competition. Players reported higher somatic and cognitive anxiety and lower self-confidence before competition compared to training, and pre-competition cortisol levels were positively correlated with both anxiety measures and negatively correlated with self-confidence. Conclusions: These findings highlight the distinct physiological and psychological responses elicited by competitive versus non-competitive settings in water polo, emphasizing the importance of considering the emotional context when monitoring athletes’ stress and recovery. The social meaning of competitive contexts may be embodied, impacting stress and immune responses. Full article

Taiwan’s subtropical climate poses substantial heat stress challenges to poultry production. This study compared four red-feathered rooster lines (n = 10 per line, BB homozygous HSP70 genotype)—three commercially bred lines (F, T, K) selected for maximum body weight, and one native trial line (TLRI-09) developed through marker-assisted selection targeting the HSP70 BB genotype—during a one-hour acute heat challenge at 42 °C. A pre-specified statistical decision tree was applied: normality was assessed by the Shapiro–Wilk test for each group’s change score (Δ = post − pre); one-way ANOVA with Tukey’s HSD was used when all groups were normally distributed; Kruskal–Wallis with Dunn’s post hoc test (Bonferroni correction) was used otherwise. Within-group pre-to-post changes were assessed by paired t-test. TLRI-09 showed a substantially lower body weight (909 ± 102 g vs. 2039–2226 g) and zero mortality, whereas each commercial line experienced one death (10%). Cloacal temperatures in F, T, and K groups exceeded the thermometer’s upper limit (>44 °C) within one hour; TLRI-09 reached only 42.8 ± 0.1 °C. Respiratory rate increment was highest in TLRI-09 (Δ = 82.0 ± 8.4 breaths/min) and differed significantly among lines (p < 0.001). Plasma T₃ change differed among lines (p = 0.006); post hoc analysis identified a significant K vs. T contrast only (p = 0.019). These results indicate that, despite sharing the same HSP70 genotype, breeding objective is an important determinant of acute thermal resilience—an observation that warrants further validation under chronic and commercial production conditions. Full article

Although the long-term behavior of ground anchors depends fundamentally on interfacial behavior, the independent effect of the strand–grout interface on load loss has not been comprehensively investigated. This study establishes a physical model testing method that isolates the strand–grout interface and systematically investigates both short-term and long-term load loss behavior. Pull-out tests and long-term monitoring tests were conducted using grout uniaxial compressive strength ($q_u$ = 18–30 MPa) and bond length ($L_b$ = 900–1500 mm) as primary design variables. Long-term monitoring confirmed that prestress loss at the strand–grout interface is induced by the progressive pull-out displacement of the strand over time, following a logarithmic decay pattern. The load reduction coefficient n was significantly more sensitive to $L_b$ than to $q_u$; n increased sharply from 0.015 to 0.069 as $L_b$ decreased. Anchors with insufficient bond length exhibited secondary load reduction behavior that disrupted the stable log-linear decay, posing significant risk to long-term performance. Based on RMSE analysis of the fitted logarithmic model, a minimum monitoring period of approximately 50 days is recommended for reliable long-term prediction when bond length is adequate. These findings identify $q_u$ and $L_b$ as the governing parameters, providing a quantitative basis for optimizing prestress design and enhancing the long-term reliability of anchor systems. Full article

Background: Lepidium meyenii Walp (L. meyenii), traditionally known as maca, is widely recognized for its health-promoting properties, including potential protection against exercise-induced muscle damage (EIMD). However, its precise effect on post-exercise blood biomarkers remains unclear. Objective: This study aimed to qualitatively review research published until April 2026 examining L. meyenii supplementation to reduce blood markers of muscle damage and protein degradation post-exertion in animal studies. Specifically, the effect size (ES) of L. meyenii supplementation on post-exercise levels of creatine kinase (CK), lactate dehydrogenase (LDH), and blood urea nitrogen (BUN) was estimated. Methods: This systematic review and meta-analysis were conducted in accordance with the PRISMA guidelines. The certainty of the evidence was assessed using the GRADE framework. Relevant studies were identified through Web of Science, Scopus, SPORTDiscus, PubMed, and MEDLINE. Eligible studies included in vivo experiments in animals with controlled designs and pre-/post-intervention assessments. Methodological quality and risk of bias were evaluated using the CAMARADES tool. Statistical analysis involved standardized mean differences (SMD) using Hedges’ g with 95% confidence intervals. Results: 15 studies were included in the systematic review, and 14 studies in animals in the meta-analysis. The CAMARADES scores ranged from 5 to 7 points, indicating moderate methodological quality. Supplementation with L. meyenii was not associated with statistically significant changes in LDH (SMD = −1.37; 95% CI −3.34 to 0.59), BUN (SMD = −0.37; 95% CI −2.16 to 1.42) nor CK (SMD = 0.29; 95% CI −5.45 to 6.03), with very high heterogeneity (I² > 97%). Exploratory subgroup analyses and meta-regression analyses by formulation type and dose did not identify any moderators that could robustly explain this heterogeneity. Conclusions: The available evidence does not support a robust overall effect of L. meyenii supplementation on blood biomarkers of muscle damage or protein catabolism in animals subjected to physical stress. The high degree of heterogeneity could not be robustly explained by either the type of formulation or the dose. These findings, which are exploratory and hypothesis-generating in nature, highlight the need for standardized, well-characterized formulations and trials with adequate statistical power. Full article

Chilling injury is a major problem limiting the postharvest storage and marketability of mango fruit at low temperature. The present study investigated the individual and combined effects of sodium nitroprusside (SNP), L-arginine (Arg) and salicylic acid (SA) on chilling tolerance, regulation of oxidative stress and the postharvest quality of ‘Keitt’ mango fruit stored at 5 ± 1 °C for 28 days followed by 4 days of shelf life at 23 °C. Fruits were pre-treated with 1 mM SNP, 1 mM Arg, 2 mM SA or their binary combinations before storage. The chilling injury, membrane damage, lipid peroxidation, protein oxidation and fruit softening were greatly enhanced by cold storage in untreated fruits. In contrast, all the treatments significantly ameliorated these deteriorative changes, and the combined treatments were superiorly effective. Among these, SNP + Arg was the most effective treatment, which reduced the chilling injury index from 4.05 in control fruits to 1.00 after shelf life, completely inhibiting the incidence of decay and reducing electrolyte leakage and malondialdehyde accumulation by 47.4 and 48.2%, respectively. The same treatment also maintained higher firmness, titratable acidity, visual appearance and ascorbic acid content than untreated fruits. The enhanced chilling tolerance was accompanied by increased antioxidant defense, as SNP + Arg significantly stimulated the activities of superoxide dismutase, catalase and peroxidase, but suppressed the activity of pectin methylesterase. Multivariate analyses, such as PCA, clustered heatmap and integrated stress index, demonstrated a strong negative relationship between oxidative stress markers and antioxidant metabolism. The results showed that combined SNP and Arg treatments enhanced chilling tolerance through increasing antioxidant capacity, preserving membrane integrity, and retarding ripening-related metabolism, which provides an effective way to maintain the postharvest quality of cold-stored mango fruit. Full article

Brittle geomaterials such as coal and rock are prone to unstable failure under high stress and dynamic disturbances, where rapid release of stored elastic strain energy can trigger dynamic disasters. Polyurea, a high-strength and high-ductility elastomer, can form a continuous flexible coating on the surface of coal/rock to regulate their deformation–fracture behavior. Here, uniaxial compression tests were performed on coal specimens coated with polyurea layers of different thicknesses (0–1.25 mm). Acoustic emission (AE) and digital image correlation (DIC) were jointly employed to characterize macroscopic deformation, microcrack evolution, fracture-mode transition, and energy partitioning. The results show that polyurea provides passive lateral confinement that suppresses lateral expansion and shifts macroscopic failure from brittle splitting to progressive ductile damage. AE-based AF–RA analysis indicates that thicker coatings increase the normal stress and shear resistance along potential fracture planes, promoting a microfracture transition from shear-dominated to tension-dominated cracking. Energy analysis demonstrates that the coating enhances pre-peak energy dissipation via coordinated deformation with the coal, while thicker coatings (≥1.00 mm) exhibit pronounced post-peak elastic tensile deformation to absorb and buffer fracture-released energy, impeding the instantaneous energy release typical of bare coal. Moreover, the elastic energy index shows that polyurea markedly reduces impact tendency, with an appropriate thickness stabilizing specimens from strong to weak/non-impact propensity. These findings clarify the coupled confinement–fracture–energy regulation mechanisms of polyurea coatings and provide quantitative guidance for coating-thickness design to mitigate dynamic failure hazards in brittle materials. Full article

Saline irrigation is a major constraint to crop production in newly reclaimed desert lands, even when pre-sowing soil salinity is low. This two-season field study evaluated whether plant growth-promoting rhizobacteria could improve barley performance under saline irrigation water with an electrical conductivity of 11.8 dS m⁻¹ in the El Moghra region, Egypt. The barley cultivar Giza 2000 was grown under five inoculation treatments: an uninoculated saline-irrigated control; a single inoculation with Azospirillum lipoferum; and combined inoculations with A. lipoferum and Bacillus coagulans, Bacillus circulans, or Enterobacter cloacae. Because freshwater was unavailable at the experimental site, treatment effects were evaluated relative to the saline-irrigated control. Across both growing seasons, single inoculation with A. lipoferum produced the most consistent improvements in growth, yield formation, nutrient accumulation, soil biological activity, and seed nutritional quality. The combined treatment of A. lipoferum and B. circulans was generally the second-most effective. Bacterial inoculation also improved adjustment to physiological stress, as indicated by greater proline accumulation, lower antioxidant enzyme activities, and enhanced expression of stress-related genes associated with proline biosynthesis and secondary metabolism. Overall, the results indicate that A. lipoferum applied alone was more effective than the tested combinations of bacteria under saline irrigation. These findings provide field-based evidence that inoculant performance depends on strain composition and that single-strain inoculation can be a promising strategy for improving barley production in reclaimed sandy soils irrigated with saline water. Full article

This study established a refined, distributed SWAT modeling framework that integrates elevation-band and snowmelt modules to reconstruct the alpine hydrological and sediment cycles of the Koshi River Basin (KRB) over the period 1990–2024, with climate scenarios constructed using the delta change approach. The KRB, a major transboundary watershed traversing China, Nepal, and India, was selected owing to its critical hydro-climatic role under the destabilizing “Asian Water Tower”; it generates substantial sediment yield, hosts the densest concentration of hydropower potential within the Ganges system, and spans an extreme vertical gradient from Mount Everest to the southern alluvial plains. Results reveal accelerated warming at a rate of 0.21 °C per decade and an overall warming–wetting trend, punctuated by an abrupt interdecadal shift around 2015. Precipitation dominated interannual streamflow variability, with enhanced rainfall triggering basin-wide sediment surges that overwhelmed the natural buffering capacity of the land surface. Conversely, rising temperatures intensified actual evapotranspiration, markedly depleting soil water and reducing total water yield and monsoon runoff, although sustained snow and glacier melt effectively elevated the dry-season low-flow baseline. The integrated climate forcing reshaped the disparity between hydrological extremes, imposing severe seasonal eco-hydrological stress that manifested as a pre-monsoon deficit in terrestrial green water and acute summer sediment outbursts for aquatic habitats. Furthermore, the flood regime exhibited an altered distribution, with mid-to-high frequency floods enhanced while low-frequency extreme flood peaks declined. The hydro-sedimentological regime consequently exhibits pronounced nonlinear responses to climate change, providing a critical, threshold-based scientific foundation for adaptive transboundary water resource management. Full article

A total of 159 wheat–Thinopyrum intermedium derivatives, originating from six Zhong partial amphiploids, were evaluated for resistance to powdery mildew (Blumeria graminis f. sp. tritici) at both seedling and adult-plant stages, as well as for field resistance to wheat aphids, together with key agronomic traits. Adult-plant resistance to powdery mildew was common across three years: 34 lines (21.4%) exhibited stable resistance, and 27 (17.0%) were moderately resistant. Resistance frequencies differed among pedigree backgrounds, with Zhong 2 & 5 derivatives showing the highest proportion of stable resistant lines (35.7%). Seedling resistance was detected in 63 lines (39.6%). Aphid resistance was less frequent, with 61 lines (38.4%) classified as resistant, including two highly resistant lines derived from Zhong 3 and Zhong 1 & 3 backgrounds. Combined resistance traits were comparatively rare. Thirty-two lines exhibited resistance to powdery mildew at both seedling and adult-plant stages, while nine lines displayed combined resistance to seedling mildew, adult mildew, and aphids. Analysis of agronomic traits indicated that environmental effects accounted for a substantial proportion of the observed phenotypic variation, whereas pedigree background and resistance responses contributed comparatively little. Correlation analyses revealed generally weak associations between resistance responses and agronomic traits, suggesting that resistance was not a major determinant of agronomic performance within the evaluated population. The identified resistant materials, therefore, represent valuable pre-breeding resources for the incorporation of resistance to multiple biotic stresses in wheat. Further genetic characterization and multi-environment evaluation will facilitate their effective utilization in wheat improvement programs. Full article

Polyamine treatments are beneficial against various stress factors due to direct protective effects and the regulation of metabolite remodelling and gene expression. However, their protective, specific effects as priming under stress conditions remain not fully understood. We hypothesised that the positive effect of priming decreases even shortly after priming. To investigate the duration of action of putrescine treatment against osmotic stress, and to reveal species- and time-dependent differences, the effects of putrescine seed-soaking were monitored in wheat and maize during osmotic stress. The putrescine pre-treatment was effective in both species against osmotic stress during three trials ran in parallel, even when the stress was applied 7 days after seed-soaking. Leaves and roots responded differently, and putrescine induced certain unique changes under control and osmotic stress conditions. The effects of the treatments at the metabolite level changed between the sub-experiments and differed between the two species. Putrescine alone had an increasing effect on jasmonic acid-isoleucine level in the roots of both wheat and maize, and it induced the expression of WRKY97 in both the leaves and roots of maize plants throughout the experiment. These results highlight that different hormonal and transcriptional changes induced by putrescine were associated with the observed positive effects. Full article

Precision agriculture increasingly relies on high-resolution, long-term remote sensing to delineate sub-field management zones. However, traditional spatial zonation assumes temporal stationarity, utilizing seasonal aggregates that obscure transient, intra-annual stress signals. This study develops a data-driven framework to characterize both persistent and non-stationary crop water use dynamics by integrating monthly, 30-m evapotranspiration (ET) data from OpenET (2000–2025) with zero-shot temporal anomaly detection. A pre-trained time-series foundation model (Chronos-T5-Small) generated counterfactual expectations for sub-field ET, quantifying deviations using a mean absolute error-based anomaly score. Unsupervised clustering of these anomaly scores with longitudinal ET metrics partitioned the landscape into dynamic biophysical regimes. Cross-registered against legacy persistence mapping based on seasonal totals, the foundation model showed strong directional agreement (86.1%, Cohen’s Kappa = 0.716) in identifying chronically constrained zones across 869 shared active pixels. Crucially, the framework identified 966 historically persistent pixels undergoing stability decay, of which 95.3% were statistically verified via paired t-tests to have collapsed into the field’s baseline variance pool. Furthermore, counterfactual anomaly detection isolated zones of recent acute divergence, differentiating enduring edaphic constraints from sudden system disruptions. This approach demonstrates how foundation models can transition from purely predictive engines to diagnostic instruments, advancing operational precision agriculture. Full article

Objectives: This study investigated the effects of exercise selection and rest interval duration on post-exercise cardiac autonomic modulation following resistance exercise (RE). Methods: Eleven (4 females) resistance-trained individuals performed a single RE session consisting of either a multi-joint exercise (back squat) or a single-joint exercise (leg extension), using rest intervals of 1 or 2 min between sets. Heart rate variability (HRV) was assessed at baseline (pre-exercise) and 30 min following the RE session. RR intervals were recorded for 15 min with participants resting in the supine position on an examination bed in a quiet environment. For HRV analysis, a 5-min artifact-free segment of RR intervals was selected and processed using Kubios HRV software, version 4.3.0 (Kubios Oy, Kuopio, Finland). The HRV metrics analyzed included the root mean square of successive differences (RMSSD), low-frequency normalized (LF), the low-frequency/high-frequency (LF/HF) ratio, and the standard deviation of transverse dispersion (SD1). Results: A significant main effect of time was observed for RMSSD, LF, and the LF/HF ratio. The back squat exercise elicited a significant reduction (p < 0.05) in vagal-related indices (RMSSD and SD1) regardless of interval duration. Longer rest intervals were associated with increased (p < 0.05) sympathetic modulation, as reflected by higher LF and LF/HF values 30 min post-exercise. No significant time × group interactions were observed for most HRV variables. Conclusions: Exercise selection and rest interval duration differentially influence post-exercise cardiac autonomic responses following RE. Multi-joint exercises induce greater vagal withdrawal, whereas longer rest intervals favor sympathetic predominance during recovery. These findings highlight the importance of manipulating RE variables to manage autonomic stress and recovery. Full article

Rock pillars in deep underground mines are subjected to complex stress environments. The combined effects of in situ stress and cyclic disturbances from mining activities lead to a redistribution of the surrounding rock mass stress field, which readily triggers instability and failure, posing severe threats to mining engineering safety. To investigate the damage mechanism of cyclic loading on rock and its weakening effect on the bearing capacity of mine pillars, this study takes limestone as the research object. A series of uniaxial compression tests were conducted on limestone specimens subjected to triaxial cyclic pre-damage, complemented by numerical simulations to further characterize the energy and deformation evolution of the damaged limestone under cyclic loading conditions. The findings are as follows: (i) Triaxial cyclic tests on limestone show that both the input energy and dissipated energy follow similar trends, decreasing rapidly in the initial stage before stabilizing. The elastic strain energy remains largely constant, with most of the input energy being stored as elastic strain energy. Under constant stress levels and cycle numbers, increases in confining pressure and frequency reduce the rock’s input energy, elastic strain energy, and dissipated energy. (ii) The peak stress of damaged limestone exhibits a positive correlation with the pre-damage confining pressure and cyclic frequency, while it decreases with an increasing number of cycles. Higher confining pressure and frequency raise the input energy, elastic potential energy, and dissipated energy at the peak stress point. (iii) Deformation and failure in damaged limestone originate from the development and propagation of localized deformation zones. Increased lateral displacement within these zones promotes the formation of macroscopic fractures. Due to significant structural heterogeneity inside the localized areas, the evolution of deformation energy is influenced by regional characteristics. (iv) Simulation results indicate that the uniaxial compressive failure of limestone involves the accumulation and propagation of micro-scale tensile cracks, which ultimately coalesce into macro-scale shear fracture surfaces. During uniaxial loading of pre-damaged limestone, newly generated cracks predominantly initiate around pre-existing cracks, with only a limited number distributed randomly. Their peak intensity shows a positive correlation with the pre-damage confining pressure. Full article

Prolonged endurance exercise performed in hot ambient conditions is associated with an increased prevalence of performance-limiting gastrointestinal perturbations. This study aimed to examine the associations between biomarkers of exercise-induced gastrointestinal syndrome (EIGS) and exercise-associated gastrointestinal symptoms (Ex-GIS) under exertional heat stress (EHS). Fifty-six non-heat acclimated endurance-trained individuals completed 2 h of steady state running at 60% maximal oxygen uptake ($\stackrel{.}{V}{\mathrm{O}}_{2\max }$) with an ambient temperature of 35.1 °C and relative humidity 29.4%. Venous blood samples were collected immediately pre- and post-exercise to quantify plasma concentrations of gastrointestinal epithelial injury and systemic inflammatory biomarkers, whilst gastrointestinal symptoms were recorded at regular intervals throughout the exercise protocol. Spearman’s rank correlation identified moderately significant relationships between interleukin-6 (IL-6) with defecation-bloody stools; interleukin-10 (IL-10) with upper abdominal pain; and IL-10, IL-1 receptor antagonist (IL-1ra), and systemic inflammatory response (SIR) profile with flatulence. Simple linear regression demonstrated that IL-6 explained a small but significant proportion of the variance defecation-bloody stool (adjusted R² = 0.094, p = 0.024); whilst variance in flatulence was independently explained by IL-10 (adjusted R² = 0.138, p = 0.025), IL-1ra (adjusted R² = 0.122, p = 0.033), and SIR-Profile (adjusted R² = 0.112, p = 0.040). These findings suggest that Ex-GIS development is multifactorial in aetiology and pathophysiology, and that symptom reporting alone likely underestimates perturbations to the gastrointestinal tract during EHS. Full article