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20 Results Found

  • Review
  • Open Access
57 Citations
10,066 Views
15 Pages

9 January 2021

Plants are functional macrobes living in a close association with diverse communities of microbes and viruses as complex systems that continuously interact with the surrounding environment. The microbiota within the plant holobiont serves various ess...

  • Article
  • Open Access
10 Citations
3,024 Views
15 Pages

From Gut to Blood: Spatial and Temporal Pathobiome Dynamics during Acute Abdominal Murine Sepsis

  • Christina Hartwig,
  • Susanne Drechsler,
  • Yevhen Vainshtein,
  • Madeline Maneth,
  • Theresa Schmitt,
  • Monika Ehling-Schulz,
  • Marcin Osuchowski and
  • Kai Sohn

Abdominal sepsis triggers the transition of microorganisms from the gut to the peritoneum and bloodstream. Unfortunately, there is a limitation of methods and biomarkers to reliably study the emergence of pathobiomes and to monitor their respective d...

  • Article
  • Open Access
1 Citations
1,892 Views
14 Pages

Microspatial Heterogeneities and the Absence of Postmortem Contamination in Alzheimer’s Disease Brain Microbiota: An Alzheimer’s Pathobiome Initiative (AlzPI) Study

  • Myat N. Thwe,
  • Yves Moné,
  • Bhaswati Sen,
  • Samuel Czerski,
  • Ahmed Azad,
  • Joshua P. Earl,
  • Donald C. Hall and
  • Garth D. Ehrlich

The discovery of profound differences in the brain microbiota of Alzheimer’s disease (AD) patients and age-matched controls (AMCs) raised questions of postmortem contamination and bacterial transport processes which could be informed by microsp...

  • Article
  • Open Access
1 Citations
2,031 Views
18 Pages

Assessment of Antimicrobial Resistance Genes and Pathobiome Diversity in Domestic Wastewater of a Tropical Country

  • Fernando Molina-Ospina,
  • Bradd Mendoza-Guido,
  • Andrea Quesada-Gonzalez,
  • Luz Chacon and
  • Mary Luz Barrios-Hernandez

23 May 2025

Wastewater treatment plants (WWTPs) are recognised as key hotspots for the dissemination of antimicrobial-resistant bacteria and antimicrobial resistance genes (ARGs). However, studies addressing the role of domestic WWTPs in the spread of resistance...

  • Article
  • Open Access
10 Citations
3,538 Views
26 Pages

Profiling Walnut Fungal Pathobiome Associated with Walnut Dieback Using Community-Targeted DNA Metabarcoding

  • Marie Belair,
  • Flora Pensec,
  • Jean-Luc Jany,
  • Gaétan Le Floch and
  • Adeline Picot

20 June 2023

Walnut dieback can be caused by several fungal pathogenic species, which are associated with symptoms ranging from branch dieback to fruit necrosis and blight, challenging the one pathogen–one disease concept. Therefore, an accurate and extensi...

  • Review
  • Open Access
19 Citations
5,322 Views
21 Pages

The Intestinal Microbiome after Traumatic Injury

  • Jennifer A. Munley,
  • Stacey L. Kirkpatrick,
  • Gwendolyn S. Gillies,
  • Letitia E. Bible,
  • Philip A. Efron,
  • Ravinder Nagpal and
  • Alicia M. Mohr

The intestinal microbiome plays a critical role in host immune function and homeostasis. Patients suffering from—as well as models representing—multiple traumatic injuries, isolated organ system trauma, and various severities of traumatic...

  • Article
  • Open Access
10 Citations
8,091 Views
15 Pages

Bartonella henselae Detected in Malignant Melanoma, a Preliminary Study

  • Marna E. Ericson,
  • Edward B. Breitschwerdt,
  • Paul Reicherter,
  • Cole Maxwell,
  • Ricardo G. Maggi,
  • Richard G. Melvin,
  • Azar H. Maluki,
  • Julie M. Bradley,
  • Jennifer C. Miller and
  • Lynne T. Bemis
  • + 6 authors

Bartonella bacilliformis (B. bacilliformis), Bartonella henselae (B. henselae), and Bartonella quintana (B. quintana) are bacteria known to cause verruga peruana or bacillary angiomatosis, vascular endothelial growth factor (VEGF)-dependent cutaneous...

  • Article
  • Open Access
4 Citations
4,194 Views
20 Pages

Protective Effects of Systiva® Seed Treatment Fungicide for the Control of Winter Wheat Foliar Diseases Caused at Early Stages Due to Climate Change

  • Ioannis Vagelas,
  • Chris Cavalaris,
  • Lefkothea Karapetsi,
  • Charalambos Koukidis,
  • Dimitris Servis and
  • Panagiotis Madesis

24 August 2022

Foliar fungal diseases are a serious threat to winter wheat production and climate change appears to favor pathogens associated with leaf blotch and tan spot symptoms in the Mediterranean area. The present work aimed to highlight these risks and prop...

  • Article
  • Open Access
20 Citations
5,346 Views
22 Pages

A Novel In Planta Enrichment Method Employing Fusarium graminearum-Infected Wheat Spikes to Select for Competitive Biocontrol Bacteria

  • Waldo Deroo,
  • Larissa De Troyer,
  • Fréderic Dumoulin,
  • Sarah De Saeger,
  • Marthe De Boevre,
  • Steven Vandenabeele,
  • Leen De Gelder and
  • Kris Audenaert

17 March 2022

This work introduces an alternative workflow for the discovery of novel bacterial biocontrol agents in wheat against Fusarium head blight (FHB). Unlike the mass testing of isolate collections, we started from a diverse inoculum by extracting microbio...

  • Communication
  • Open Access
10 Citations
3,260 Views
16 Pages

30 July 2023

Fusarium basal rot disease (FBR) is a destructive threat to onion crops around the globe. It causes seedlings’ death, development disruption, and pre- and post-harvest bulb infection and rotting, with a concern for toxin infestation. It is an e...

  • Article
  • Open Access
3 Citations
4,145 Views
14 Pages

Cultivar Susceptibility to Olive Knot Disease and Association with Endophytic Microbiota Community

  • Grazia Licciardello,
  • Alexandros Mosca,
  • Silvia Di Silvestro,
  • Damiano Puglisi,
  • Maria Patrizia Russo,
  • Vittoria Catara and
  • Paola Caruso

4 February 2023

Olive knot disease (OKD) induced by the bacterium Pseudomonas savastanoi pv. savastanoi seriously affects olive production in the Mediterranean basin. Nowadays, the only strategies to control the disease are pruning and the application of cupric...

  • Review
  • Open Access
2 Citations
1,860 Views
21 Pages

4 July 2025

Phytoplasmas are wall-less, phloem-restricted bacteria responsible for numerous significant plant diseases worldwide. An increasing body of evidence indicates that phytoplasmas can coexist with other pathogens in mixed infections, including various 1...

  • Article
  • Open Access
644 Views
20 Pages

Potential Bacterial Biomarkers Associated with Penaeus stylirostris Shrimp Larvae to Infer Holobiont Health and Dysbiosis Across Larvae Stages

  • Nolwenn Callac,
  • Carolane Giraud,
  • Valérie Perez,
  • Dominique Ansquer,
  • Jean-Sébastien Lam,
  • Viviane Boulo,
  • Dominique Pham and
  • Nelly Wabete

Microbiota play a pivotal role in holobionts, influencing nutrient intake, growth, and overall health. In this context, microbial dysbiosis of Penaeus stylirostris larvae seem to be associated with huge larval mortalities in hatcheries in New Caledon...

  • Article
  • Open Access
534 Views
19 Pages

Microbial Imbalance and Stochastic Assembly Drive Gut Dysbiosis in White-Gill Diseased Larimichthys crocea (Richardson, 1846)

  • Xuan Wang,
  • Huangwei Cheng,
  • Ting Liu,
  • Xuelei Wang,
  • Xiongfei Wu,
  • Junqi Yu,
  • Demin Zhang,
  • Weiliang Shen and
  • Dandi Hou

White-gill disease has emerged as one of the major health threats in large yellow croaker Larimichthys crocea (Richardson, 1846) aquaculture, yet its underlying microbial mechanisms remain poorly understood. In this study, we investigated the gut mic...

  • Review
  • Open Access
68 Citations
12,052 Views
17 Pages

The Importance of the Microbiome in Critically Ill Patients: Role of Nutrition

  • Rocio Moron,
  • Julio Galvez,
  • Manuel Colmenero,
  • Per Anderson,
  • José Cabeza and
  • Maria Elena Rodriguez-Cabezas

7 December 2019

Critically ill patients have an alteration in the microbiome in which it becomes a disease-promoting pathobiome. It is characterized by lower bacterial diversity, loss of commensal phyla, like Firmicutes and Bacteroidetes, and a domination of pathoge...

  • Article
  • Open Access
9 Citations
5,626 Views
24 Pages

Salmo salar Skin and Gill Microbiome during Piscirickettsia salmonis Infection

  • Marcos Godoy,
  • Yoandy Coca,
  • Rudy Suárez,
  • Marco Montes de Oca,
  • Jacob W. Bledsoe,
  • Ian Burbulis,
  • Diego Caro,
  • Juan Pablo Pontigo,
  • Vinicius Maracaja-Coutinho and
  • César Sáez-Navarrete
  • + 2 authors

27 December 2023

Maintaining the high overall health of farmed animals is a central tenant of their well-being and care. Intense animal crowding in aquaculture promotes animal morbidity especially in the absence of straightforward methods for monitoring their health....

  • Article
  • Open Access
5 Citations
5,710 Views
15 Pages

23 November 2023

Superelongation disease (SED) is a fungal disease that affects cassava in the Caribbean. The symptoms include the appearance of dry necrotic spots and lesions on the leaves, which may severely affect the plant yield. However, the primary causal patho...

  • Review
  • Open Access
5 Citations
5,281 Views
17 Pages

Tailored Pre-Operative Antibiotic Prophylaxis to Prevent Post-Operative Surgical Site Infections in General Surgery

  • Mason Vierra,
  • Mohsen Rouhani Ravari,
  • Fatemeh Soleymani Sardoo and
  • Benjamin D. Shogan

The average American today undergoes three inpatient and two outpatient surgical procedures during one’s life, each of which carries with it a risk of post-operative infection. It has long been known that post-operative infections cause signifi...

  • Review
  • Open Access
13 Citations
5,966 Views
29 Pages

Antimicrobial multidrug resistance (MDR) is a global challenge, not only for public health, but also for sustainable agriculture. Antibiotics used in humans should be ruled out for use in veterinary or agricultural settings. Applying antimicrobial pe...

  • Feature Paper
  • Article
  • Open Access
4 Citations
3,353 Views
27 Pages

Fusarium basal rot (FBR) places a significant limitation on Allium production worldwide. The damage caused by the disease can be observed throughout the entire crop cycle. This research aimed to further our understanding of the impact of FBR on the c...