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Search Results (339)

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Keywords = orthognathic surgeries

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14 pages, 871 KiB  
Article
Evaluation of Deviations Produced by Soft Tissue Fitting in Virtually Planned Orthognathic Surgery
by Álvaro Pérez-Sala, Pablo Montes Fernández-Micheltorena, Miriam Bobadilla, Ricardo Fernández-Valadés Gámez, Javier Martínez Goñi, Ángela Villanueva, Iñigo Calvo Archanco, José Luis Del Castillo Pardo de Vera, José Luis Cebrián Carretero, Carlos Navarro Cuéllar, Ignacio Navarro Cuellar, Gema Arenas, Ana López López, Ignacio M. Larrayoz and Rafael Peláez
Appl. Sci. 2025, 15(15), 8478; https://doi.org/10.3390/app15158478 (registering DOI) - 30 Jul 2025
Viewed by 364
Abstract
Orthognathic surgery (OS) is a complex procedure commonly used to treat dentofacial deformities (DFDs). These conditions, related to jaw position or size and often involving malocclusion, affect approximately 15% of the population. Due to the complexity of OS, accurate planning is essential. Digital [...] Read more.
Orthognathic surgery (OS) is a complex procedure commonly used to treat dentofacial deformities (DFDs). These conditions, related to jaw position or size and often involving malocclusion, affect approximately 15% of the population. Due to the complexity of OS, accurate planning is essential. Digital assessment using computer-aided design (CAD) and computer-aided manufacturing (CAM) tools enhances surgical predictability. However, limitations in soft tissue simulation often require surgeon input to optimize aesthetic results and minimize surgical impact. This study aimed to evaluate the accuracy of virtual surgery planning (VSP) by analyzing the relationship between planning deviations and surgical satisfaction. A single-center, retrospective study was conducted on 16 patients who underwent OS at San Pedro University Hospital of La Rioja. VSP was based on CT scans using Dolphin Imaging software (v12.0, Patterson Dental, St. Paul, MN, USA) and surgeries were guided by VSP-designed occlusal splints. Outcomes were assessed using the Orthognathic Quality of Life (OQOL) questionnaire and deviations were measured through pre- and postoperative imaging. The results showed high satisfaction scores and good overall outcomes, despite moderate deviations from the virtual plan in many cases, particularly among Class II patients. A total of 63% of patients required VSP modifications due to poor soft tissue fitting, with 72% of these being Class II DFDs. Most deviations involved less maxillary advancement than planned, while maintaining optimal occlusion. This suggests that VSP may overestimate advancement needs, especially in Class II cases. No significant differences in satisfaction were observed between patients with low (<2 mm) and high (>2 mm) deviations. These findings support the use of VSP as a valuable planning tool for OS. However, surgeon experience remains essential, especially in managing soft tissue behavior. Improvements in soft tissue prediction are needed to enhance accuracy, particularly for Class II DFDs. Full article
(This article belongs to the Special Issue Intelligent Medicine and Health Care, 2nd Edition)
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8 pages, 232 KiB  
Article
Clinical Analysis of TMJ Replacement Using a Customized Prosthesis
by Sergio Olate, Víctor Ravelo, Gonzalo Muñoz, Carlos Gaete, Rodrigo Goya and Rômulo Valente
J. Clin. Med. 2025, 14(15), 5314; https://doi.org/10.3390/jcm14155314 - 28 Jul 2025
Viewed by 201
Abstract
Background/Objectives: This study aims to uncover the variables related to the success of the intervention. Methods: A retrospective study was conducted on patients who underwent joint replacement surgery utilizing a customized alloplastic system between 2018 and 2023, comprising subjects with complete records for [...] Read more.
Background/Objectives: This study aims to uncover the variables related to the success of the intervention. Methods: A retrospective study was conducted on patients who underwent joint replacement surgery utilizing a customized alloplastic system between 2018 and 2023, comprising subjects with complete records for both the planning and follow-up phases. The Student’s t-test was applied with a significance threshold of p < 0.05. Results: Forty-eight subjects were admitted for initial analysis, and 31 subjects were evaluated with a minimum follow-up of 1 year and a maximum of 7 years, with a mean age of 36.37 ± 15.53. The TMJ diagnosis was mainly with degenerative TMJ disease, followed by ankylosis and craniofacial syndromes, and an average of 2.1 ± 1.2 previous surgeries were noted. Degenerative joint disease correlated with increased pain (p < 0.0001) and a higher prevalence of prior joint surgery (p < 0.0001). Thirty-one subjects were followed up with 47 prostheses installed; 74.4% underwent complementary surgery with other facial osteotomies. Significant improvements (p < 0.0001) were observed when comparing pain levels pre- and postoperatively, with a decrease from 5.5 (±2.3) to 2.2 (±0.4). Concerning the interincisal opening, there was a significant increase (p < 0001) from 25.85 (±10.2) mm to 35.93 (±4.2) mm in mouth opening. TMJ replacement treatment is efficient and effective, demonstrating stability in follow-up assessments for up to 7 years. Conclusions: The indications for replacement are diverse and may benefit patients who have not yet progressed to end-stage TMJ disease. Full article
(This article belongs to the Special Issue Innovations in Plastic and Reconstructive Research)
15 pages, 1800 KiB  
Article
Digital Orthodontic Setups in Orthognathic Surgery: Evaluating Predictability and Precision of the Workflow in Surgical Planning
by Olivier de Waard, Frank Baan, Robin Bruggink, Ewald M. Bronkhorst, Anne Marie Kuijpers-Jagtman and Edwin M. Ongkosuwito
J. Clin. Med. 2025, 14(15), 5270; https://doi.org/10.3390/jcm14155270 - 25 Jul 2025
Viewed by 324
Abstract
Background: Inadequate presurgical planning is a key contributor to suboptimal outcomes in orthognathic surgery. This study aims to assess the accuracy of a digital surgical planning workflow conducted prior to any orthodontic intervention. Methods: Digital planning was performed for 26 patients before orthodontic [...] Read more.
Background: Inadequate presurgical planning is a key contributor to suboptimal outcomes in orthognathic surgery. This study aims to assess the accuracy of a digital surgical planning workflow conducted prior to any orthodontic intervention. Methods: Digital planning was performed for 26 patients before orthodontic treatment (T0) and compared to the actual preoperative planning (T1). Digitized plaster casts were merged with CBCT data and converted to orthodontic setups to create a 3D virtual head model. After voxel-based registration of T0 and T1, dental arches were virtually osteotomized and repositioned according to planned outcomes. These T0 segments were then aligned with T1 planning using bony landmarks of the maxilla. Anatomical landmarks were used to construct virtual triangles on maxillary and mandibular segments, enabling assessment of positional and orientational differences. Transformations between T0 and T1 were translated into clinically meaningful metrics. Results: Significant differences were found between T0 and T1 at the dental level. T1 exhibited a greater clockwise rotation of the dental maxilla (mean: 2.85°) and a leftward translation of the mandibular dental arch (mean: 1.19 mm). In SARME cases, the bony mandible showed larger anti-clockwise roll differences. Pitch variations were also more pronounced in maxillary extraction cases, with both the dental maxilla and bony mandible demonstrating increased clockwise rotations. Conclusions: The proposed orthognathic surgical planning workflow shows potential for simulating mandibular outcomes but lacks dental-level accuracy, especially in maxillary anterior torque. While mandibular bony outcome predictions align reasonably with pretreatment planning, notable discrepancies exceed clinically acceptable thresholds. Current accuracy limits routine use; further refinement and validation in larger, homogeneous patient groups are needed to enhance clinical reliability and applicability. Full article
(This article belongs to the Special Issue Orthodontics: Current Advances and Future Options)
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12 pages, 1611 KiB  
Article
Foreign Body in the Masticatory Space as a Rare Complication of Orthognathic Surgery and Associated Dental Procedures: A Case Series and Literature Review
by Andrea Frosolini, Antonino Ungaro, Flavia Cascino, Linda Latini, Valerio Ramieri, Paolo Gennaro and Guido Gabriele
J. Clin. Med. 2025, 14(15), 5234; https://doi.org/10.3390/jcm14155234 - 24 Jul 2025
Viewed by 227
Abstract
Background: Foreign bodies (FBs) within the masticatory space are a rare but significant complication of oral and maxillofacial procedures. Despite advancements in orthognathic surgery, instrument breakage and accidental loss can lead to challenging secondary procedures. Clinical experience with retained foreign bodies in [...] Read more.
Background: Foreign bodies (FBs) within the masticatory space are a rare but significant complication of oral and maxillofacial procedures. Despite advancements in orthognathic surgery, instrument breakage and accidental loss can lead to challenging secondary procedures. Clinical experience with retained foreign bodies in the masticatory space following orthognathic surgery and related dental procedures is summarized. Methods: A retrospective search was conducted in the surgical and radiological database of a tertiary referral center for maxillofacial surgery, covering procedures from January 2017 to December 2024. Patients were included if they had undergone orthognathic surgery and presented with a retained FB in the masticatory space confirmed through imaging. Clinical records, operative notes, imaging studies, and follow-up data were reviewed. Results: Out of 2092 procedures, four patients (0.19%) were identified. Two FBs were related to broken surgical instruments during orthognathic surgery (a suture needle and a burr fragment), while two were fractured local anesthesia needles during third molar extraction under local anesthesia. All FBs were located in deep compartments of the masticatory space (paramandibular or pterygopalatine region). Surgical retrieval via transoral approach under general anesthesia was successful in all cases. One patient experienced transient facial nerve dyskinesia; no long-term complications or recurrences were noted. Conclusions: Retained foreign bodies in the masticatory space are infrequent yet warrant prompt recognition and surgical management to mitigate the risk of infection, nerve damage, and repeated procedures. Thorough instrument checks, proper technique, and advanced imaging modalities are crucial for minimizing these complications in orthognathic surgery. Full article
(This article belongs to the Special Issue New Perspective of Oral and Maxillo-Facial Surgery)
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12 pages, 6587 KiB  
Article
Overcoming the Limitations of Conventional Orthognathic Surgery: A Novel Approach Using Implate
by Valerio Ramieri, Laura Viola Pignataro, Tito Matteo Marianetti, Davide Spadoni, Andrea Frosolini and Paolo Gennaro
J. Clin. Med. 2025, 14(14), 5012; https://doi.org/10.3390/jcm14145012 - 15 Jul 2025
Viewed by 321
Abstract
Introduction: This manuscript addresses the limitations of traditional orthognathic surgery in achieving both functional and aesthetic correction in patients with Class II malocclusion and severe mandibular retrusion. Current techniques often struggle to simultaneously address mandibular deficiency and inadequate transverse dimension, leading to [...] Read more.
Introduction: This manuscript addresses the limitations of traditional orthognathic surgery in achieving both functional and aesthetic correction in patients with Class II malocclusion and severe mandibular retrusion. Current techniques often struggle to simultaneously address mandibular deficiency and inadequate transverse dimension, leading to unsatisfactory outcomes. Methods: Seven male patients underwent bimaxillary osteotomy with mandibular advancement. A novel surgical plate, Implate, was used, which was designed to facilitate precise osteotomy and stabilization. Pre-surgical planning included CBCT scanning, 3D modeling, and surgical simulation. Postoperative assessments included clinical examinations, CT and OPT scans. Results: Implate successfully addressed the challenges of conventional techniques, minimizing the formation of bony steps and achieving a more harmonious facial profile. The minimally invasive procedure, with careful periosteal and muscle management, contributed to stable outcomes, and no complications were reported. At the 6-month follow-up, OPT analysis showed a mean mandibular width increase of 18.1 ± 6.2 mm and vertical ramus height gains of 6.0 ± 3.1 mm (left) and 5.8 ± 1.7 mm (right). Conclusions: According to our preliminary experience, the integration of Implate into surgical practice offers a significant improvement in treating complex Class II malocclusions. By simultaneously correcting mandibular retrusion and width while minimizing complications, Implate provides a superior solution compared to traditional methods. This innovative approach highlights the potential of combining advanced surgical techniques with personalized 3D-printed implants to achieve optimal functional and aesthetic outcomes. Further prospective studies with controls and longer follow-up are needed to validate the efficacy and reproducibility of Implate in wider clinical use. Full article
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16 pages, 3137 KiB  
Systematic Review
Correction of Anterior Open Bite Using Temporary Anchorage Devices: A Systematic Review and Meta-Analysis
by Patricia Burgos-Lancero, Marta Ibor-Miguel, Laura Marqués-Martínez, Paula Boo-Gordillo, Esther García-Miralles and Clara Guinot-Barona
J. Clin. Med. 2025, 14(14), 4958; https://doi.org/10.3390/jcm14144958 - 13 Jul 2025
Viewed by 439
Abstract
Background/Objectives: Anterior open bite (AOB) is a complex malocclusion characterized by the lack of vertical overlap between the upper and lower teeth during maximum intercuspation. It often results in functional impairments and aesthetic concerns. Traditional treatments for adult patients, including orthognathic surgery, are [...] Read more.
Background/Objectives: Anterior open bite (AOB) is a complex malocclusion characterized by the lack of vertical overlap between the upper and lower teeth during maximum intercuspation. It often results in functional impairments and aesthetic concerns. Traditional treatments for adult patients, including orthognathic surgery, are effective but invasive. Temporary anchorage devices (TADs) have emerged as a minimally invasive alternative. The aim of this systematic review and meta-analysis was to evaluate the effectiveness of TADs for molar intrusion in the correction of AOB. Methods: A systematic review was conducted according to the PRISMA 2020 guidelines. An electronic search was performed in PubMed and Scopus until March 2025. The inclusion criteria comprised clinical studies in humans published in English or Spanish in the last 10 years. The risk of bias was assessed using RoB 2, ROBINS-I, and the Joanna Briggs Institute tools. A random-effects meta-analysis was carried out to estimate pooled intrusion values, and heterogeneity was evaluated using Cochran’s Q test and the I2 statistic. Results: Twelve studies were included. Molar intrusion using TADs achieved significant overbite improvements, with a pooled mean intrusion of 1.70 mm (95% CI: 0.53–2.87 mm). The heterogeneity among studies was high (I2 = 88.5%). Despite variability in force magnitude and TAD type, lighter forces were generally associated with similar outcomes and fewer adverse effects. Conclusions: TADs offer a predictable and less invasive alternative to orthognathic surgery for AOB correction. When appropriately indicated and biomechanically managed, they provide effective vertical control and short- to medium-term stability in adult patients. Full article
(This article belongs to the Special Issue Latest Advances in Orthodontics)
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12 pages, 1504 KiB  
Article
Precision of the Fully Digital 3D Treatment Plan in Orthognathic Surgery
by Paula Locmele, Oskars Radzins, Martins Lauskis, Girts Salms, Anda Slaidina and Andris Abeltins
J. Clin. Med. 2025, 14(14), 4916; https://doi.org/10.3390/jcm14144916 - 11 Jul 2025
Viewed by 252
Abstract
Background/Objectives: The aim of this study was to investigate the accuracy of implementing a virtual treatment plan in orthognathic surgery. Methods: The study included 30 patients (11 males and 19 females with a mean age of 23.7 years) with a digital surgical plan. [...] Read more.
Background/Objectives: The aim of this study was to investigate the accuracy of implementing a virtual treatment plan in orthognathic surgery. Methods: The study included 30 patients (11 males and 19 females with a mean age of 23.7 years) with a digital surgical plan. All patients underwent bimaxillary orthognathic surgery: LeFort I osteotomy of the maxilla combined with bilateral split sagittal osteotomy (BSSO) of the mandible. Eleven landmarks on the pre-surgical (planned) model and the same landmarks on the post-surgical model were used for comparison and linear difference measurements between the real and predicted outcomes in all three planes—transversal, sagittal, and vertical. Results: All median values fell within the 2 mm range in the transversal plane, and the mean displacement was 0.57 mm. In the sagittal and vertical planes, the treatment outcome in the maxilla was more precise than in the mandible. The mean displacement in the sagittal plane was −0.88 mm and that in the vertical plane was 0.44 mm. All deviations were less than 2 mm. Conclusions: The data obtained in this study show that the digital surgical plan for orthognathic surgery is clinically reliable in all planes. Full article
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37 pages, 438 KiB  
Review
Three-Dimensionally Printed Splints in Dentistry: A Comprehensive Review
by Luka Šimunović, Samir Čimić and Senka Meštrović
Dent. J. 2025, 13(7), 312; https://doi.org/10.3390/dj13070312 - 10 Jul 2025
Viewed by 646
Abstract
Three-dimensional (3D) printing has emerged as a transformative technology in dental splint fabrication, offering significant advancements in customization, production speed, material efficiency, and patient comfort. This comprehensive review synthesizes the current literature on the clinical use, benefits, limitations, and future directions of 3D-printed [...] Read more.
Three-dimensional (3D) printing has emerged as a transformative technology in dental splint fabrication, offering significant advancements in customization, production speed, material efficiency, and patient comfort. This comprehensive review synthesizes the current literature on the clinical use, benefits, limitations, and future directions of 3D-printed dental splints across various disciplines, including prosthodontics, orthodontics, oral surgery, and restorative dentistry. Key 3D printing technologies such as stereolithography (SLA), digital light processing (DLP), and material jetting are discussed, along with the properties of contemporary photopolymer resins used in splint fabrication. Evidence indicates that while 3D-printed splints generally meet ISO standards for flexural strength and wear resistance, their mechanical properties are often 15–30% lower than those of heat-cured PMMA in head-to-head tests (flexural strength range 50–100 MPa vs. PMMA 100–130 MPa), and study-to-study variability is high. Some reports even show significantly reduced hardness and fatigue resistance in certain resins, underscoring material-specific heterogeneity. Clinical applications reviewed include occlusal stabilization for bruxism and temporomandibular disorders, surgical wafers for orthognathic procedures, orthodontic retainers, and endodontic guides. While current limitations include material aging, post-processing complexity, and variability in long-term outcomes, ongoing innovations—such as flexible resins, multi-material printing, and AI-driven design—hold promise for broader adoption. The review concludes with evidence-based clinical recommendations and identifies critical research gaps, particularly regarding long-term durability, pediatric applications, and quality control standards. This review supports the growing role of 3D printing as an efficient and versatile tool for delivering high-quality splint therapy in modern dental practice. Full article
(This article belongs to the Special Issue Digital Dentures: 2nd Edition)
15 pages, 1327 KiB  
Article
Aesthetic Impact of Orthognathic Surgery vs. Orthodontic Camouflage in Class II Division 1 Patients with Convex Facial Profile: A Follow-Up Using Combined Frontal and Profile Views
by Simos Psomiadis, Iosif Sifakakis, Ioannis Iatrou and Nikolaos Gkantidis
J. Clin. Med. 2025, 14(12), 4277; https://doi.org/10.3390/jcm14124277 - 16 Jun 2025
Viewed by 783
Abstract
Background/Objectives: A previous study evaluating convex facial profiles at rest demonstrated that combined orthodontic and orthognathic surgical treatment is more effective in enhancing facial aesthetics compared to orthodontic camouflage alone. The present follow-up study aimed to reassess these findings by incorporating both [...] Read more.
Background/Objectives: A previous study evaluating convex facial profiles at rest demonstrated that combined orthodontic and orthognathic surgical treatment is more effective in enhancing facial aesthetics compared to orthodontic camouflage alone. The present follow-up study aimed to reassess these findings by incorporating both profile and frontal facial views in the aesthetic evaluation. Methods: This retrospective cohort study sample included 36 consecutively selected patients with convex facial profiles and Class II Division 1 malocclusion. Two groups of 18 non-growing patients with similar characteristics were compared. Group A was treated with orthodontics and orthognathic surgery, whereas Group B was treated with orthodontics exclusively. Pre- and post-treatment profile and frontal facial photographs were simultaneously presented to orthodontists, oral and maxillofacial surgeons, convex profile patients, and laypeople, asking them to assess changes in facial appearance. Results: Significant positive changes in facial appearance were perceived for Group A, in contrast to no changes for Group B, with a difference of 17/100 visual analogue scale (VAS) units. The rater groups demonstrated a high degree of consistency (ICC > 0.88). Multivariate analysis revealed significant differences in perceived changes between the two treatment groups (F = 14.63, p < 0.001, Pillai’s Trace = 0.36, and partial η2 = 0.36), with no significant effects from the rater group (p > 0.05). Similar results are evident when only profile photos were rated (p > 0.05). Conclusions: The combined orthodontic and orthognathic surgery approach effectively enhances facial appearance in convex profile cases, whereas orthodontic treatment alone does not result in significant changes. These findings should be clearly communicated during patient consultations and considered in treatment planning. Full article
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14 pages, 352 KiB  
Review
Comparative Analysis of Fully Guided and Free-Hand Orthognathic Surgery: Advancements, Precision, and Clinical Outcomes
by Sophia Tsokkou, Ioannis Konstantinidis, Antonios Keramas, Georgios Kiosis, Kanellos Skourtsidis, Danai Alexiou, Georgia-Nektaria Keskesiadou, Sofia Karachrysafi, Theodora Papamitsou and Ioannis Chatzistefanou
Dent. J. 2025, 13(6), 260; https://doi.org/10.3390/dj13060260 - 11 Jun 2025
Viewed by 464
Abstract
Background/Objectives: Orthognathic surgery has evolved with digital advancements, improving precision and predictability. Traditional free-hand techniques rely on surgeon expertise, often leading to variable outcomes. Fully guided approaches integrate computer-assisted surgery, including virtual surgical planning (VSP), CAD/CAM, and dynamic navigation, enhancing accuracy and [...] Read more.
Background/Objectives: Orthognathic surgery has evolved with digital advancements, improving precision and predictability. Traditional free-hand techniques rely on surgeon expertise, often leading to variable outcomes. Fully guided approaches integrate computer-assisted surgery, including virtual surgical planning (VSP), CAD/CAM, and dynamic navigation, enhancing accuracy and efficiency. This review compares these approaches, assessing their impact on surgical accuracy, efficiency, and patient outcomes. Methods: A scoping review was conducted across PubMed, MEDLINE, Scopus, Cochrane Library, and Embase databases, focusing on clinical trials and cohort studies. Key parameters analyzed include surgical precision, operative efficiency, complication rates, and functional/aesthetic results. Results: Fully guided techniques achieve sub-millimetric accuracy with mean length deviations ranging from 1.3 mm to 2.4 mm and mean angular deviations between 2.29° and 3.51°. Moreover, these approaches markedly reduce operative time, averaging between 34 min and 1.7 h, and postoperative complications. Digital tools streamline workflow, improving reproducibility and aesthetic outcomes. Free-hand methods remain cost-effective but require greater surgical expertise, often resulting in longer recovery periods and higher variability. Conclusions: Computer-assisted orthognathic surgery enhances precision and efficiency, outperforming free-hand techniques in accuracy and predictability. While free-hand methods remain viable for simpler cases, fully guided approaches optimize surgical execution. Future research should explore hybrid strategies combining digital precision with manual adaptability to further refine surgical techniques. Full article
(This article belongs to the Special Issue Dentistry in the 21st Century: Challenges and Opportunities)
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13 pages, 2395 KiB  
Case Report
Non-Extraction Orthodontic Camouflage for Severe Class II Malocclusion Post-TMJ Gap Arthroplasty: A Case Report
by Eser Rengin Nalbantoglu, Sina Uckan and Parmjit Singh
Oral 2025, 5(2), 45; https://doi.org/10.3390/oral5020045 - 10 Jun 2025
Viewed by 781
Abstract
Background/Objectives: Orthodontic camouflage is a treatment strategy designed to address mild to moderate skeletal discrepancies through dental compensation when growth modification or orthognathic surgery (OGS) is unsuitable or declined by the patient. This report highlights the treatment of a child with a skeletal [...] Read more.
Background/Objectives: Orthodontic camouflage is a treatment strategy designed to address mild to moderate skeletal discrepancies through dental compensation when growth modification or orthognathic surgery (OGS) is unsuitable or declined by the patient. This report highlights the treatment of a child with a skeletal Class II pattern, Class II division 1 malocclusion, a 10.8 mm overjet, traumatic overbite, and unilateral temporomandibular joint (TMJ) ankylosis on the left side. Methods: The treatment plan focused on correcting the proclination of the maxillary incisors and improving the facial profile. A non-extraction camouflage approach using pre-adjusted edgewise appliances was implemented following a gap arthroplasty procedure on the left TMJ. Results: The patient achieved a satisfactory treatment outcome, with an ideal static and functional occlusion and significant improvement in facial esthetics. The approach effectively managed the severe mandibular retrognathia and TMJ ankylosis without OGS, thereby minimizing the risk of progressive condylar resorption. Conclusions: This case underscores the importance of personalized treatment plans tailored to each patient’s dental, skeletal, and individual needs. It demonstrates that non-surgical camouflage treatments can be a viable alternative for addressing severe mandibular retrognathia with TMJ ankylosis, achieving favorable esthetic and functional outcomes. Full article
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19 pages, 1614 KiB  
Article
The Occlusal Contact Area Is Associated with the Magnitude but Not Peak Timing of Changes in Chewing-Induced Brain Blood Flow in Mandibular Prognathism
by Hiroyuki Kanzaki, Chihiro Kariya, Kana Yoshida, Yuri Inagawa, Masao Kumazawa and Hiroshi Tomonari
Dent. J. 2025, 13(6), 250; https://doi.org/10.3390/dj13060250 - 3 Jun 2025
Viewed by 1184
Abstract
Background/Objectives: Jaw deformities affect not only facial aesthetics but also various oral functions. While previous studies have demonstrated that mandibular prognathism (MP) alters masticatory-induced brain blood flow (BBF), the temporal characteristics of these hemodynamic changes have remained unclear. In this cross-sectional observational [...] Read more.
Background/Objectives: Jaw deformities affect not only facial aesthetics but also various oral functions. While previous studies have demonstrated that mandibular prognathism (MP) alters masticatory-induced brain blood flow (BBF), the temporal characteristics of these hemodynamic changes have remained unclear. In this cross-sectional observational study, we investigated the following two specific objectives: (1) whether food hardness affects not only the magnitude but also the temporal patterns of BBF changes during mastication and (2) how malocclusion is associated with these temporal hemodynamic responses. Methods: Twenty-six participants with normal occlusion (NORM) and twenty patients with MP participated in this study. BBF was measured using functional near-infrared spectroscopy, while participants chewed soft paraffin or hard gummy candy. Maximum oxygenated hemoglobin (oxy-Hb) values and time-to-peak BBF were analyzed. Results: While food hardness did not significantly affect maximum oxy-Hb within groups, the MP group showed significantly lower responses during hard gummy candy mastication compared to the NORM group. The occlusal contact area exhibited significant positive correlation with maximum oxy-Hb values, while the ANB angle, an indicator of intermaxillary skeletal relationship, showed no significant correlation with BBF parameters. The hard gummy candy/paraffin ratio of maximum oxy-Hb was significantly higher in the NORM group compared to the MP group. Time-to-peak BBF was approximately twice as long for hard gummy candy compared to paraffin in both groups, with no significant differences between groups. Conclusions: These findings reveal that while MP attenuates the magnitude of masticatory-induced BBF, particularly during hard food mastication, the temporal adaptation to increased food hardness is preserved. This dissociation between magnitude and timing effects suggests that intact basic neurovascular coupling mechanisms would be maintained even in the condition of altered masticatory function in a MP subject, which is providing new insights for rehabilitation strategies in orthognathic surgery cases. Full article
(This article belongs to the Topic Oral Health Management and Disease Treatment)
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17 pages, 3070 KiB  
Article
Virtual Guided and Customized Orthognathic Surgery in Patients with Obstructive Sleep Apnea Syndrome: Accuracy and Clinical Outcomes
by Marta Benito Anguita, Saad Khayat, Soledad López Martín, Natalia Bravo Quelle, Ignacio Navarro Cuéllar, Ana López López, José Luis Cebrián Carretero, José Luis del Castillo Pardo de Vera, Pablo Montes Fernández-Micheltorena, Manuel Tousidonis Rial, Giovanni Dell’Aversana Orabona, Farzin Falahat, José Zamorano León and Carlos Navarro Cuéllar
J. Clin. Med. 2025, 14(11), 3780; https://doi.org/10.3390/jcm14113780 - 28 May 2025
Viewed by 744
Abstract
Background: This preliminary case series aimed to evaluate the clinical and morphometric outcomes of maxillomandibular advancement (MMA) surgery in patients with severe obstructive sleep apnea (OSA) using virtual surgical planning (VSP), patient-specific cutting guides, and customized titanium plates. Primary outcomes included changes in [...] Read more.
Background: This preliminary case series aimed to evaluate the clinical and morphometric outcomes of maxillomandibular advancement (MMA) surgery in patients with severe obstructive sleep apnea (OSA) using virtual surgical planning (VSP), patient-specific cutting guides, and customized titanium plates. Primary outcomes included changes in the Apnea–Hypopnea Index (AHI), airway dimensions, surgical accuracy, and quality of life. Methods: In this preliminary case series, six patients with severe OSA underwent MMA surgery planned using three-dimensional VSP, and executed with the aid of CAD-/CAM-generated surgical guides and patient-specific osteosynthesis. Clinical variables included AHI, Epworth Sleepiness Scale (ESS), and computed tomography-based airway morphometry. Surgical accuracy was assessed by comparing planned and achieved skeletal movements. Statistical analysis was performed using Wilcoxon signed-rank tests and Spearman’s correlation. Results: The mean preoperative AHI decreased significantly from 48.8 ± 23.6 to 12.4 ± 10.0 (p = 0.035), and ESS scores improved from 14.5 ± 4.6 to 7.8 ± 2.1 (p = 0.029). Mean airway area increased significantly from 51.8 ± 9.0 mm2 to 91.8 ± 26.6 mm2 (p = 0.035). A strong but non-significant correlation was observed between airway gain and ESS improvement (p = 0.754, p = 0.084). No patients required CPAP at 6-month follow-up, and all were asymptomatic. The anteroposterior accuracy of skeletal movements was high: 82.6% for the maxilla and 85.8% for the pogonion, with mean absolute errors of 1.25 mm and 1.95 mm, respectively. Vertical accuracy was lower, particularly in the chin region, where error analysis showed greater variability. No statistically significant differences were found between planned and achieved movements in any vector. Conclusions: MMA surgery performed with VSP, cutting guides, and customized titanium plates offers a highly effective, safe, and precise treatment modality for selected OSA patients. This approach leads to a significant reduction in AHI, expansion of the upper airway, and improvement in patient-reported daytime functioning. High accuracy in skeletal repositioning—particularly in anteroposterior vectors—supports the reliability and reproducibility of digitally guided orthognathic surgery. These findings reinforce the role of technologically assisted MMA as a definitive treatment for severe OSA. Full article
(This article belongs to the Special Issue Innovations in Maxillofacial Surgery)
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11 pages, 1091 KiB  
Article
Evaluation of Mandibular Fixation Techniques Using Monocortical Plates After Mandibular Setback Surgery
by Seung-Woo Lee, Bong-Jin Jeong and Junho Jung
Life 2025, 15(6), 845; https://doi.org/10.3390/life15060845 - 23 May 2025
Viewed by 424
Abstract
This study aimed to evaluate mandibular fixation techniques using monocortical plates following sagittal split ramus osteotomy in skeletal Class III patients. Ninety-three patients were categorized into three groups based on fixation methods: four-hole miniplate with one proximal and two distal screws (Group 1); [...] Read more.
This study aimed to evaluate mandibular fixation techniques using monocortical plates following sagittal split ramus osteotomy in skeletal Class III patients. Ninety-three patients were categorized into three groups based on fixation methods: four-hole miniplate with one proximal and two distal screws (Group 1); four-hole miniplate with four screws (Group 2); sliding plate with two proximal and one distal screws (Group 3). Cone-beam computed tomography scans were obtained at three time points: immediately postoperative (T1), 6 months (T2), and 12 months (T3). The yaw, roll, and pitch rotations of the proximal segment, as well as horizontal and vertical changes of the pogonion, were evaluated. Group 1 exhibited significantly greater counterclockwise rotation of the proximal segments at T2 (p = 0.021) and T3 (p = 0.035) compared to the other groups. Additionally, Group 1 showed significantly smaller anterior and superior displacement of the pogonion at T3 (0.97 ± 2.10 mm, p = 0.009; 0.03 ± 1.62 mm, p = 0.011, respectively). Following surgical wafer removal, intimate occlusal contact is archived and the elimination of premature contacts through postoperative orthodontic treatment contributes to counterclockwise autorotation of the mandible. Therefore, anterior and superior movements of the pogonion are expected if firm fixation between the proximal and distal segments is achieved. Therefore, these findings suggest that a single proximal screw, as seen in a three-screw fixation, may act as a fulcrum, insufficiently resisting postoperative clockwise rotation of the distal segments. Full article
(This article belongs to the Section Medical Research)
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Article
Retrospective Analysis of Surgical Site Infection After Titanium Plate Removal Following Orthognathic Surgery
by Kazuyuki Yusa, Tomoharu Hemmi, Satoshi Kasuya, Nobuyuki Sasahara and Shigeo Ishikawa
J. Clin. Med. 2025, 14(11), 3657; https://doi.org/10.3390/jcm14113657 - 23 May 2025
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Abstract
Background/Objectives: This study aimed to investigate associations between surgical site infection (SSI) and plate removal following orthognathic surgery. Methods: The study sample consisted of 191 patients (126 females, 65 males). Plate removal was performed in 174 patients with a mean age of 26.4 [...] Read more.
Background/Objectives: This study aimed to investigate associations between surgical site infection (SSI) and plate removal following orthognathic surgery. Methods: The study sample consisted of 191 patients (126 females, 65 males). Plate removal was performed in 174 patients with a mean age of 26.4 ± 9.7 years. Multiple logistic regression analysis was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for risk factors for SSI after plate removal. Results: Forty-three patients developed SSI after plate removal. The only risk factor independently associated with SSI after plate removal was a history of SSI after orthognathic surgery (OR 2.476, 95% CI 1.040–5.892). Conclusions: Patients who experience SSI after orthognathic surgery are at higher risk of SSI after plate removal, so protocols for perioperative management should be carefully considered. Full article
(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
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