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Search Results (1,195)

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Keywords = mental health prediction

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19 pages, 357 KiB  
Article
Resilience and Mobbing Among Nurses in Emergency Departments: A Cross-Sectional Study
by Aristotelis Koinis, Ioanna V. Papathanasiou, Ioannis Moisoglou, Ioannis Kouroutzis, Vasileios Tzenetidis, Dimitra Anagnostopoulou, Pavlos Sarafis and Maria Malliarou
Healthcare 2025, 13(15), 1908; https://doi.org/10.3390/healthcare13151908 - 5 Aug 2025
Abstract
Background: Moral harassment (mobbing) in healthcare, particularly among nurses, remains a persistent issue with detrimental effects on mental health, resilience, and quality of life. Aim: We examine the relationship between the resilience of nurses working in Emergency Departments (EDs) and how these factors [...] Read more.
Background: Moral harassment (mobbing) in healthcare, particularly among nurses, remains a persistent issue with detrimental effects on mental health, resilience, and quality of life. Aim: We examine the relationship between the resilience of nurses working in Emergency Departments (EDs) and how these factors influence experiences of workplace mobbing. Methods: This cross-sectional study included 90 nurses from four public hospitals in Greece’s 5th Health District. Data were collected between October 2023 and March 2024 using the WHOQOL-BREF, Workplace Psychologically Violent Behaviors (WPVB) scale and the Connor–Davidson Resilience Scale (CD-RISC). The sample consisted primarily of full-time nurses (84.3% female; mean age = 43.1 years), with 21.1% reporting chronic conditions. Most participants were married (80.0%) and had children (74.4%), typically two (56.1%). Statistical analyses—conducted using SPSS version 27.0—included descriptive statistics, Pearson and Spearman correlations, multiple linear regression, and mediation analysis, with significance set at p < 0.05. Results: Resilience was moderate (mean = 66.38%; Cronbach’s α = 0.93) and positively correlated with all WHOQOL-BREF domains—physical, psychological, social, and environmental (r = 0.30–0.40)—but not with the overall WHOQOL-BREF. The mean overall WHOQOL-BREF score was 68.4%, with the lowest scores observed in the environmental domain (mean = 53.76%). Workplace mobbing levels were low to moderate (mean WPVB score = 17.87), with subscale reliabilities ranging from α = 0.78 to 0.95. Mobbing was negatively associated with social relationships and the environmental WHOQOL-BREF (ρ = –0.23 to –0.33). Regression analysis showed that cohabitation and higher resilience significantly predicted better WHOQOL-BREF outcomes, whereas mobbing was not a significant predictor. Mediation analysis (bootstrap N = 5000) indicated no significant indirect effect of resilience in the relationship between mobbing and WHOQOL-BREF. Conclusions: Resilience was identified as a key protective factor for nurses’ quality of life in emergency care settings. Although workplace mobbing was present at low-to-moderate levels, it was negatively associated with specific WHOQOL-BREF domains. Enhancing mental resilience among nurses may serve as a valuable strategy to mitigate the psychological effects of moral harassment in healthcare environments. Full article
(This article belongs to the Special Issue Health and Social Care Policy—2nd Edition)
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13 pages, 241 KiB  
Article
The Pivotal Role of Social Support, Self-Compassion and Self-Care in Predicting Physical and Mental Health Among Mothers of Young Children
by Shiran Bord, Liron Inchi, Yuval Paldi, Ravit Baruch, Miriam Schwartz Shpiro, Shani Ronen, Limor Eizenberg, Ilana Gens and Maya Yaari
Healthcare 2025, 13(15), 1889; https://doi.org/10.3390/healthcare13151889 - 1 Aug 2025
Viewed by 220
Abstract
Background: Mothers’ health significantly affects their well-being and that of their families. The early years of motherhood can be tough and impact mental health. This study examined the associations between mothers’ self-compassion, social support, and self-care behaviors and their physical and mental well-being. [...] Read more.
Background: Mothers’ health significantly affects their well-being and that of their families. The early years of motherhood can be tough and impact mental health. This study examined the associations between mothers’ self-compassion, social support, and self-care behaviors and their physical and mental well-being. Methods: In August 2023, an online cross-sectional survey was conducted among 514 Israeli mothers with children under three. Mothers’ physical and mental health was assessed using SF12. Self-compassion was measured by the Self-Compassion Scale (SCS). Social support was evaluated through the Multidimensional Scale of Perceived Social Support (MSPSS), and self-care was assessed via the Pittsburgh Enjoyable Activities Test (PEAT). Results: Respondents’ average age was 31.5 years. Their self-reported physical health was relatively high, with a mean of 78.36 (SD = 21) on a 0–100 scale (n = 442). Mental health scores were lower, with a mean of 65.88 (SD = 20.28, n = 401). Perceived physical health was higher among Jewish mothers, younger mothers, and those with higher income levels. Additionally, greater social support and self-compassion correlated with better perceived physical health (Adj R2 = 0.11, p < 0.001). For mental health, higher scores were observed among Jewish mothers, younger mothers, and full-time employed mothers. Furthermore, higher social support, self-compassion, and self-care practices were associated with improved perceptions of mental health (Adj R2 = 0.39, p < 0.001). Conclusions: Promoting the well-being of mothers is crucial for their health, their children’s well-being, and the family unit. Health professionals working with mothers of young children should emphasize and help promote social support, self-compassion, and self-care activities. Full article
16 pages, 287 KiB  
Article
An Analysis of Chronic Stress, Substance Use, and Mental Health Among a Sample of Young Sexual Minority Men in New York City: The P18 Cohort Study
by Michael Briganti, Hao Liu, Marybec Griffin and Perry N. Halkitis
Youth 2025, 5(3), 79; https://doi.org/10.3390/youth5030079 - 1 Aug 2025
Viewed by 102
Abstract
Introduction: Sexual minority men (SMM) are at increased risk for psychosocial stressor exposure, substance use, and poor mental health relative to heterosexual men. While the burden of mental health is growing in the United States, among SMM these trends are increasing at a [...] Read more.
Introduction: Sexual minority men (SMM) are at increased risk for psychosocial stressor exposure, substance use, and poor mental health relative to heterosexual men. While the burden of mental health is growing in the United States, among SMM these trends are increasing at a greater rate, driving health disparities. Methods: Framed within a minority stress framework, these analyses examine how stressors explain substance use and poorer mental health over time. Participants were asked questions on stressor exposure (stigma, discrimination, internalized homophobia, perceived stress), mental health (anxiety, depression, PTSD), and substance use (alcohol to intoxication, club drugs, poly club drugs) over 36 months among 528 SMM in NYC. Results: Perceived stress increased frequency of all substance use, whereas discrimination decreased days of club and poly club drug use. Depression severity predicted increased days of club drug and poly club drug use. PTSD severity predicted increased days of club drug and poly club drug use. Conclusion: We are able to expand on the literature with granular substance use data to highlight associations with stressors and mental health. These findings support an increased need for systematic policy solutions and public health interventions to address drivers of substance use disparities among young SMM. Full article
16 pages, 291 KiB  
Article
General and Specific Social Trust as Predictors of Depressive Symptoms: Evidence from Post-Crisis Iceland
by Haukur Freyr Gylfason
World 2025, 6(3), 107; https://doi.org/10.3390/world6030107 - 1 Aug 2025
Viewed by 236
Abstract
Social trust has been linked to the development and severity of depression, but trust is a complex, multidimensional construct. This study examines the extent to which two distinct forms of trust, general trust and specific trust, predict depressive symptoms. Drawing on longitudinal data [...] Read more.
Social trust has been linked to the development and severity of depression, but trust is a complex, multidimensional construct. This study examines the extent to which two distinct forms of trust, general trust and specific trust, predict depressive symptoms. Drawing on longitudinal data from the Directorate of Health’s national surveys conducted in 2007 and 2009, the analysis includes responses from 3211 Icelanders selected through a stratified random sample. Depressive symptoms were assessed using the Depression, Anxiety, and Stress Scale (DASS), while specific trust captured trust in close relationships, and general trust measured broader perceptions of trustworthiness in others. The two forms of trust together explained 7.6% of the variance in depressive symptoms, with specific trust contributing a substantially greater share. Both remained significant predictors after controlling for prior depression and physical health. These findings highlight the protective role of specific trust and suggest that general trust, an indicator of broader social capital, may also help buffer against depression. The results underscore the relevance of trust as a public health resource and support continued research into social determinants of mental health in Iceland. Full article
16 pages, 808 KiB  
Article
Work-Related Low Back Pain and Psychological Distress Among Physiotherapists in Saudi Arabia: A Cross-Sectional Study
by Amjad Abdullah Alsenan, Mohamed K. Seyam, Ghada M. Shawky, Azza M. Atya, Mohamed A. Abdel Ghafar and Shahnaz Hasan
Healthcare 2025, 13(15), 1853; https://doi.org/10.3390/healthcare13151853 - 30 Jul 2025
Viewed by 227
Abstract
Background: Musculoskeletal disorders significantly affect healthcare professionals, particularly physiotherapists, due to the physical demands of their work. The link between physical ailments and psychological distress is especially prominent in clinical settings. Objectives: To assess the prevalence of work-related low back pain [...] Read more.
Background: Musculoskeletal disorders significantly affect healthcare professionals, particularly physiotherapists, due to the physical demands of their work. The link between physical ailments and psychological distress is especially prominent in clinical settings. Objectives: To assess the prevalence of work-related low back pain (LBP), stress, anxiety, and depression among physiotherapists in Saudi Arabia, and to identify associated local risk factors. Methods: A cross-sectional study using convenience sampling included 710 licensed physiotherapists across Saudi Arabia. Participants completed an online survey containing demographic data and the validated measures, including the Visual Analog Scale (VAS) for pain, the Oswestry Disability Index (ODI), and the Depression, Anxiety, and Stress Scale-21 (DASS-21) for psychological distress. Data were analysed using descriptive statistics, chi-square tests, correlation, and regression analyses. Results: Of 710 responses, 697 were valid; 378 physiotherapists reported work-related LBP. The mean pain intensity was 4.6 (SD = 1.6), with 54.2% experiencing moderate to severe disability. Mental health results showed 49.7% had depressive symptoms and 33.9% experienced some level of anxiety. Significant correlations were observed between disability and psychological distress (anxiety: r = 0.382; depression: r = 0.375; stress: r = 0.406; all p < 0.001). Regression analyses indicated psychological distress significantly predicted disability, with R2 values ranging from 0.125 to 0.248, being higher among inpatient physiotherapists. Conclusions: This study reveals a high prevalence of LBP and psychological distress among Saudi physiotherapists, with stress being the strongest predictor of LBP severity. Integrated ergonomic and mental health interventions, including workplace wellness programs and psychological support, are recommended to reduce risks and promote a healthier, more sustainable physiotherapy workforce. Full article
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15 pages, 276 KiB  
Article
Association Between Patient Sociodemographic and Clinical Characteristics and Acute Mental Health Service Utilization Within One Year Following Enrollment in the Rapid Access and Stabilization Program in Nova Scotia
by Medard K. Adu, Samuel Obeng Nkrumah, Belinda Agyapong, Gloria Obuobi-Donkor, Ejemai Eboreime, Lori Wozney and Vincent Israel Opoku Agyapong
J. Clin. Med. 2025, 14(15), 5241; https://doi.org/10.3390/jcm14155241 - 24 Jul 2025
Viewed by 264
Abstract
Background/Objectives: The Rapid Access and Stabilization Program (RASP), launched in Nova Scotia in April 2023, aims to improve timely psychiatric care, reduce reliance on emergency services, and provide early intervention. This study describes the sociodemographic and clinical characteristics of the RASP participants [...] Read more.
Background/Objectives: The Rapid Access and Stabilization Program (RASP), launched in Nova Scotia in April 2023, aims to improve timely psychiatric care, reduce reliance on emergency services, and provide early intervention. This study describes the sociodemographic and clinical characteristics of the RASP participants and examines their association with acute service use. Methods: This cross-sectional descriptive study used self-reported surveys and administrative data from 738 RASP participants. Descriptive statistics summarized key sociodemographic and clinical variables. Associations between these characteristics and acute service use (emergency department visits, inpatient admissions, and mobile crisis calls) were examined using chi-square and Fisher’s Exact tests. Bonferroni correction was applied for multiple comparisons. Results: The sample was predominantly female (65.2%) and aged 20–40 years (38.4%). Despite high rates of severe anxiety (53.9%) and depression (36.0%), acute service use was low: emergency department visits (7.2%), mobile crisis calls (1.0%), and inpatient admissions (0.8%). Preliminary analyses showed that education level and housing status were associated with ED visits and inpatient admissions. However, these associations did not remain statistically significant after Bonferroni correction. Conclusions: Although mental health symptom severity was high, acute mental health service use remained low after RASP enrollment, indicating the program’s potential in reducing reliance on crisis services. No participant characteristics were significantly associated with acute service use after adjustment, underscoring the complexity of predicting utilization and the need for robust multivariable models. Continued investment in rapid access programs may be essential to improving timely mental health care and supporting early intervention strategies. Full article
(This article belongs to the Section Mental Health)
12 pages, 851 KiB  
Article
How Does Physical Activity Affect the Mental Health of Adults with Intellectual Disability? A Cross-Sectional Study Analyzing the Complex Interplay Between Variables
by Tommaso Piva, Andrea Raisi, Valentina Zerbini, Sabrina Masotti, Erica Menegatti, Alessandro Grande, Giovanni Grazzi, Gianni Mazzoni, Emilio Paolo Visintin, Martino Belvederi Murri and Simona Mandini
J. Funct. Morphol. Kinesiol. 2025, 10(3), 285; https://doi.org/10.3390/jfmk10030285 - 24 Jul 2025
Viewed by 257
Abstract
Background: Individuals with intellectual disability face an increased risk of mental health issues compared to the general population. Despite the proven efficacy of physical activity (PA) in improving anxiety and depression in the general population, little is known about this relationship in adults [...] Read more.
Background: Individuals with intellectual disability face an increased risk of mental health issues compared to the general population. Despite the proven efficacy of physical activity (PA) in improving anxiety and depression in the general population, little is known about this relationship in adults with intellectual disability and the factors that influence it. The purpose of the study was to determine whether a correlation exists between PA and perceived levels of anxiety and depression, and assess gender disparities in PA and mental health. Method: People with intellectual disability were recruited from day centers and sports events. The amount of PA was evaluated through the International Physical Activity Questionnaire. Perceived mental health was assessed through the Zung Self-Rating Anxiety (ZAS) and Depression Scale (ZDS). Results: In total, 99 adults (34 females, aged 33 ± 12) participated in the study. A gender disparity was found in anxiety levels, while depression, PA, and type of sport participation did not differ between males and females. Multiple regression analysis highlights how the depression score was significantly predicted by gender (β = −3.57, p = 0.015), intellectual disability level (β =−3.08, p < 0.008), and PA (β =−0.10, p= 0.001), while anxiety was influenced by gender (β = −4.48, p = 0.003) and intellectual disability level (β = −3.23, p = 0.007). Conclusions: These findings underscore the relevance of physical activity as a factor associated with lower depressive symptoms in adults with intellectual disability, highlighting its potential role in mental health promotion within this population. Full article
(This article belongs to the Section Physical Exercise for Health Promotion)
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12 pages, 236 KiB  
Article
Should an Anesthesiologist Be Interested in the Patient’s Personality? Relationship Between Personality Traits and Preoperative Anesthesia Scales of Patients Enrolled for a Hip Replacement Surgery
by Jakub Grabowski, Agnieszka Maryniak, Dariusz Kosson and Marcin Kolacz
J. Clin. Med. 2025, 14(15), 5227; https://doi.org/10.3390/jcm14155227 - 24 Jul 2025
Viewed by 258
Abstract
Background: Preparing patients for surgery considers assessing the patient’s somatic health, for example by the American Society of Anesthesiology (ASA) scale or the Revised Cardiac Risk Index (RCRI), known as the Lee index. This process usually ignores mental functioning (personality and anxiety), which [...] Read more.
Background: Preparing patients for surgery considers assessing the patient’s somatic health, for example by the American Society of Anesthesiology (ASA) scale or the Revised Cardiac Risk Index (RCRI), known as the Lee index. This process usually ignores mental functioning (personality and anxiety), which is known to influence health. The purpose of this study is to analyze the existence of a relationship between personality traits (the Big Five model and trait-anxiety) and anesthesia scales (ASA scale, Lee index) used for the preoperative evaluation of patients. Methods: The study group comprised 102 patients (59 women, 43 men) scheduled for hip replacement surgery. Patients completed two psychological questionnaires: the NEO-FFI (NEO Five Factors Inventory) and the X-2 STAI (State-Trait Anxiety Inventory) sheet. Next, the presence and possible strength of the relationship between personality traits and demographic and medical variables were analyzed using Spearman’s rho rank correlation coefficient. Results: Patients with a high severity of trait anxiety are classified higher on the ASA scale (rs = 0.359; p < 0.001). Neuroticism, defined according to the Big Five model, significantly correlates with scales of preoperative patient assessment: the ASA classification (rs = 0.264; p < 0.001) and the Lee index (rs = 0.202; p = 0.044). A hierarchical regression model was created to test the possibility of predicting ASA scores based on personality. It explained more than 34% of the variance and was a good fit to the data (p < 0.05). The controlled variables of age and gender accounted for more than 23% of the variance. Personality indicators (trait anxiety, neuroticism) additionally accounted for slightly more than 11% of the variance. Trait anxiety (Beta = 0.293) proved to be a better predictor than neuroticism (Beta = 0.054). Conclusions: These results indicate that inclusion of personality screening in the preoperative patient evaluation might help to introduce a more individualized approach to patients, which could result in better surgical outcomes. Full article
(This article belongs to the Special Issue Perioperative Anesthesia: State of the Art and the Perspectives)
16 pages, 508 KiB  
Article
Exploring the Role of Self-Forgiveness to Explain the Relationship Between Religiosity and Wellbeing in Individuals with Serious Mental Illness
by Sandra D. Reid, Shelly-Ann Hunte, Marielle Joseph and Marsha Ivey
Religions 2025, 16(8), 955; https://doi.org/10.3390/rel16080955 - 23 Jul 2025
Viewed by 281
Abstract
Self-forgiveness is identified as a contributor to psychological wellbeing and may serve as a mechanism through which religiosity supports mental health. There is a dearth of research on wellbeing and the role of self-forgiveness in the English-speaking Caribbean. This preliminary study explored the [...] Read more.
Self-forgiveness is identified as a contributor to psychological wellbeing and may serve as a mechanism through which religiosity supports mental health. There is a dearth of research on wellbeing and the role of self-forgiveness in the English-speaking Caribbean. This preliminary study explored the relationship between religiosity, self-forgiveness, and wellbeing among persons with serious mental illness (SMI), a population largely overlooked in this context. A convenience sample of 362 out-patients receiving care in Trinidad and Tobago completed self-reported measures of self-forgiveness, the Religious Commitment Inventory, and Havard’s Flourishing Measure. Inferential statistics examined group differences in religiosity and wellbeing, and predictive relationships among key variables. Among persons with SMI, higher religiosity was significantly associated with greater wellbeing (p < 0.0001). Additionally, there was greater wellbeing among those who reported a propensity to self-forgive compared to those who did not (p < 0.0001). Self-forgiveness explained a significant part of the relationship between religiosity and wellbeing. Furthermore, among the non-highly religious, self-forgiveness was also significantly associated with greater wellbeing (p < 0.001). Our findings suggest that self-forgiveness may mediate the link between religiosity and wellbeing, highlighting its potential as a therapeutic coping mechanism for individuals with serious mental illness. This study adds to the growing literature on religious coping in mental health and underscores the need for further research to clarify the mediating role of self-forgiveness. Full article
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32 pages, 1548 KiB  
Article
The Emergence of Ecological Consciousness: A Transformative Journey
by McKenna Corvello, Cerine Benomar and Stefania Maggi
Youth 2025, 5(3), 76; https://doi.org/10.3390/youth5030076 - 23 Jul 2025
Viewed by 368
Abstract
The global youth mental health crisis is increasingly intertwined with climate change, as young people experience heightened climate anxiety and ecological grief. This study examines the relationship between nature connectedness, climate worry, coping strategies, and mental health outcomes among Canadian university students. Drawing [...] Read more.
The global youth mental health crisis is increasingly intertwined with climate change, as young people experience heightened climate anxiety and ecological grief. This study examines the relationship between nature connectedness, climate worry, coping strategies, and mental health outcomes among Canadian university students. Drawing on Pihkala’s process model of eco-anxiety, we propose the Developing Ecological Consciousness Model, a three-act framework that traces young people’s journey from climate awareness to meaningful engagement. Using path analysis on two independent samples (N = 1825), we found that nature connectedness predicts increased climate worry, which in turn correlates with higher levels of depression and anxiety. However, meaning-focused coping emerged as a protective factor, mitigating these negative mental health impacts. Problem-focused coping alone was insufficient, highlighting the need for balanced strategies. The study underscores the dual role of nature connectedness—both as a source of climate distress and a foundation for resilience. These findings highlight the need for interventions that foster ecological consciousness while addressing the emotional toll of climate change, offering insights for policymakers, educators, and mental health practitioners working with youth in a warming world. Full article
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16 pages, 283 KiB  
Article
Pre-Mastectomy Breast Reconstruction Intentions in Women with Breast Cancer: Psychosocial and Personality Predictors Informing Mental Health Promotion
by Valentini Bochtsou, Eleni I. Effraimidou, Maria Samakouri, Spyridon Plakias, Maria-Eleni Zachou and Aikaterini Arvaniti
Healthcare 2025, 13(14), 1761; https://doi.org/10.3390/healthcare13141761 - 21 Jul 2025
Viewed by 771
Abstract
Background/Objectives: Despite the psychological benefits of breast reconstruction (BR) after mastectomy, uptake remains limited among women with breast cancer. This study explores psychosocial and personality predictors of BR intentions in the pre-mastectomy phase, aiming to inform strategies for mental health promotion in oncology [...] Read more.
Background/Objectives: Despite the psychological benefits of breast reconstruction (BR) after mastectomy, uptake remains limited among women with breast cancer. This study explores psychosocial and personality predictors of BR intentions in the pre-mastectomy phase, aiming to inform strategies for mental health promotion in oncology care. Methods: This cross-sectional analysis used preoperative data from a longitudinal study at a university hospital in Greece. Women with primary breast cancer scheduled for mastectomy completed a battery of validated self-report measures, including the International Personality Item Big-Five Factor Markers (IPIP-BFFM), the Hospital Anxiety and Depression Scale (HADS), and the Short Form-36 Health Survey (SF-36). Demographic, clinical, and psychosocial data were also collected. Binary logistic regression was used to examine predictors of (a) BR information-seeking and (b) BR intention. Results: Seventy-four women participated (mean age = 61.1 years). Older age predicted lower BR intention (Exp(b) = 0.897, 95% CI: 0.829–0.970) and information-seeking (Exp(b) = 0.925, 95% CI: 0.859–0.997). Single/divorced status was associated with reduced BR information-seeking (Exp(b) = 0.053, 95% CI: 0.005–0.549). Openness to experience significantly predicted both outcomes (BR information-seeking: Exp(b) = 1.115, 95% CI: 1.028–1.209); BR intention: Exp(b) = 1.095, 95% CI: 1.016–1.181). Higher physical health-related QoL scores were associated with increased BR intention (Exp(b) = 1.039, 95% CI: 1.007–1.072), whereas higher mental health-related QoL (Exp(b) = 0.952, 95% CI: 0.912–0.994) and higher depression scores (Exp(b) = 0.797, 95% CI: 0.638–0.996) were linked to decreased BR intent. No psychological factor significantly predicted information-seeking. Conclusions: These findings underscore the value of psychosocial screening and personality-informed counseling prior to surgery. By identifying individuals less likely to seek information or consider BR, pre-mastectomy assessments can contribute to tailored, mental health-promoting interventions and support informed, patient-centered surgical decision-making. Full article
27 pages, 4187 KiB  
Article
Assessing Occupational Work-Related Stress and Anxiety of Healthcare Staff During COVID-19 Using Fuzzy Natural Language-Based Association Rule Mining
by Abdulaziz S. Alkabaa, Osman Taylan, Hanan S. Alqabbaa and Bulent Guloglu
Healthcare 2025, 13(14), 1745; https://doi.org/10.3390/healthcare13141745 - 18 Jul 2025
Viewed by 249
Abstract
Background/Objective: Frontline healthcare staff who contend diseases and mitigate their transmission were repeatedly exposed to high-risk conditions during the COVID-19 pandemic. They were at risk of mental health issues, in particular, psychological stress, depression, anxiety, financial stress, and/or burnout. This study aimed to [...] Read more.
Background/Objective: Frontline healthcare staff who contend diseases and mitigate their transmission were repeatedly exposed to high-risk conditions during the COVID-19 pandemic. They were at risk of mental health issues, in particular, psychological stress, depression, anxiety, financial stress, and/or burnout. This study aimed to investigate and evaluate the occupational stress of medical doctors, nurses, pharmacists, physiotherapists, and other hospital support crew during the COVID-19 pandemic in Saudi Arabia. Methods: We collected both qualitative and quantitative data from a survey given to public and private hospitals using methods like correspondence analysis, cluster analysis, and structural equation models to investigate the work-related stress (WRS) and anxiety of the staff. Since health-related factors are unclear and uncertain, a fuzzy association rule mining (FARM) method was created to address these problems and find out the levels of work-related stress (WRS) and anxiety. The statistical results and K-means clustering method were used to find the best number of fuzzy rules and the level of fuzziness in clusters to create the FARM approach and to predict the work-related stress and anxiety of healthcare staff. This innovative approach allows for a more nuanced appraisal of the factors contributing to work-related stress and anxiety, ultimately enabling healthcare organizations to implement targeted interventions. By leveraging these insights, management can foster a healthier work environment that supports staff well-being and enhances overall productivity. This study also aimed to identify the relevant health factors that are the root causes of work-related stress and anxiety to facilitate better preparation and motivation of the staff for reorganizing resources and equipment. Results: The results and findings show that when the financial burden (FIN) of healthcare staff increased, WRS and anxiety increased. Similarly, a rise in psychological stress caused an increase in WRS and anxiety. The psychological impact (PCG) ratio and financial impact (FIN) were the most influential factors for the staff’s anxiety. The FARM results and findings revealed that improving the financial situation of healthcare staff alone was not sufficient during the COVID-19 pandemic. Conclusions: This study found that while the impact of PCG was significant, its combined effect with FIN was more influential on staff’s work-related stress and anxiety. This difference was due to the mutual effects of PCG and FIN on the staff’s motivation. The findings will help healthcare managers make decisions to reduce or eliminate the WRS and anxiety experienced by healthcare staff in the future. Full article
(This article belongs to the Special Issue Depression, Anxiety and Emotional Problems Among Healthcare Workers)
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18 pages, 3116 KiB  
Article
Effects of Probiotic Supplementation on Depressive Symptoms, Sleep Quality, and Modulation of Gut Microbiota and Inflammatory Biomarkers: A Randomized Controlled Trial
by S Rehan Ahmad, Abdullah M. AlShahrani and Anupriya Kumari
Brain Sci. 2025, 15(7), 761; https://doi.org/10.3390/brainsci15070761 - 18 Jul 2025
Viewed by 1299
Abstract
Background: More than merely determining our sleep pattern, our body’s internal clock also improves the quality of our sleep, alleviates the symptoms of depression, and maintains the balance of our gut flora. Methods: We carried out a 12-week randomized controlled trial with 99 [...] Read more.
Background: More than merely determining our sleep pattern, our body’s internal clock also improves the quality of our sleep, alleviates the symptoms of depression, and maintains the balance of our gut flora. Methods: We carried out a 12-week randomized controlled trial with 99 adults from Kolkata, New Delhi, and Pune who reported sleep problems and symptoms of depression or anxiety. Participants received either a probiotic formulated to improve sleep quality and reduce depressive symptoms or a placebo. We tracked sleep using overnight studies and wearable devices, assessed depressive symptoms with standardized questionnaires, and analyzed stool samples to profile gut bacteria and their metabolites using gene sequencing and metabolomics. Advanced statistics and machine learning helped us pinpoint the key microbial and metabolic factors tied to sleep and mental health. Results: At the start, participants with disrupted sleep and depressive symptoms had fewer beneficial gut bacteria like Bifidobacterium and Lactobacillus, more inflammation-related microbes, and lower levels of helpful short-chain fatty acids. These imbalances were linked to poorer sleep efficiency, less REM sleep, and higher depression and anxiety scores. After 12 weeks, those taking the circadian-supporting probiotic saw a statistically significant increase in beneficial gut bacteria, improved sleep efficiency (+7.4%, p = 0.02), and greater reductions in depression and anxiety compared to the placebo. Increases in SCFA-producing bacteria most strongly predicted improvements. Conclusions: Our results show that taking a probiotic supplement can help bring your gut back into balance, support better sleep, and lift symptoms of depression and anxiety. This offers a hopeful and practical option for people looking for real relief from these deeply connected challenges. Full article
(This article belongs to the Special Issue Relationships Between Disordered Sleep and Mental Health)
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15 pages, 874 KiB  
Article
Depression, Anxiety, and Stress Symptoms in Women with Rheumatic Disease of Reproductive Age: Lessons from the COVID-19 Pandemic
by Nora Rosenberg, Antonia Mazzucato-Puchner, Peter Mandl, Valentin Ritschl, Tanja Stamm and Klara Rosta
J. Clin. Med. 2025, 14(14), 5038; https://doi.org/10.3390/jcm14145038 - 16 Jul 2025
Viewed by 358
Abstract
Background: Women with systemic autoimmune rheumatic disease (SARD) are at higher risk of developing infection-related complications, anxiety, and depression. Using the example of the COVID-19 pandemic, we aimed to explore the impact of this external stressor on symptoms of depression, anxiety, and stress [...] Read more.
Background: Women with systemic autoimmune rheumatic disease (SARD) are at higher risk of developing infection-related complications, anxiety, and depression. Using the example of the COVID-19 pandemic, we aimed to explore the impact of this external stressor on symptoms of depression, anxiety, and stress in a sample of women with SARD in a cross-sectional study design. Methods: Females aged 18–50 with SARD were enrolled from 04/2021 to 04/2022 at the Medical University of Vienna or through an online self-help group, while snowball sampling was used to recruit an age-matched healthy control group. Participants completed questionnaires including: (1) demographic information, medical history, and access to healthcare; (2) the Depression, Anxiety, and Stress Scale (DASS-21); and (3) the Coronavirus Anxiety Scale (CAS). Parameters were compared between groups using Chi-squared, Fisher’s exact, and Mann–Whitney U tests. Linear regression analysis was used to investigate which individual factors predicted the DASS-21 in women with SARD. Results: The study sample consisted of 226 women (n = 99 with SARD and n = 127 healthy controls). Women with SARD reported lower DASS-21 stress (p = 0.008) and CAS scores (p = 0.057) than the control group. There were no significant differences in DASS-21 anxiety or depression scores. Among women with SARD, a linear regression model identified the most important predictors of DASS-21 as access to rheumatological care (p = 0.002) and recent disease activity (p = 0.028). Conclusions: Despite the pandemic, women with SARD reported mental health outcomes equal to or better than those of the healthy control group. Continued access to rheumatological care may serve as an important protective factor for their mental health during large-scale crises like pandemics. Full article
(This article belongs to the Special Issue Diagnosis and Treatment of Rheumatic Diseases)
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Article
Transformer-Based Decomposition of Electrodermal Activity for Real-World Mental Health Applications
by Charalampos Tsirmpas, Stasinos Konstantopoulos, Dimitris Andrikopoulos, Konstantina Kyriakouli and Panagiotis Fatouros
Sensors 2025, 25(14), 4406; https://doi.org/10.3390/s25144406 - 15 Jul 2025
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Abstract
Decomposing Electrodermal Activity (EDA) into phasic (short-term, stimulus-linked responses) and tonic (longer-term baseline) components is essential for extracting meaningful emotional and physiological biomarkers. This study presents a comparative analysis of knowledge-driven, statistical, and deep learning-based methods for EDA signal decomposition, with a focus [...] Read more.
Decomposing Electrodermal Activity (EDA) into phasic (short-term, stimulus-linked responses) and tonic (longer-term baseline) components is essential for extracting meaningful emotional and physiological biomarkers. This study presents a comparative analysis of knowledge-driven, statistical, and deep learning-based methods for EDA signal decomposition, with a focus on in-the-wild data collected from wearable devices. In particular, the authors introduce the Feel Transformer, a novel Transformer-based model adapted from the Autoformer architecture, designed to separate phasic and tonic components without explicit supervision. The model leverages pooling and trend-removal mechanisms to enforce physiologically meaningful decompositions. Comparative experiments against methods such as Ledalab, cvxEDA, and conventional detrending show that the Feel Transformer achieves a balance between feature fidelity (SCR frequency, amplitude, and tonic slope) and robustness to noisy, real-world data. The model demonstrates potential for real-time biosignal analysis and future applications in stress prediction, digital mental health interventions, and physiological forecasting. Full article
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