Search Results (72)

Background/Objective: The criteria for selecting and managing oral moisturizers have yet to be clearly defined. The purpose of this study was to examine the effects of storage temperature and storage time on the pH and oxidation–reduction potential (ORP) of oral moisturizers. Methods: The pH and ORP of 20 commercially available oral moisturizers stored at 37 °C, 25 °C, and 4 °C were measured immediately after opening (0M) and at 1 month (1M), 3 months (3M), and 6 months (6M) post-opening. The data were analyzed using Fisher’s exact test based on the critical pH of enamel and dentin, two-way repeated-measures analysis of variance (ANOVA), and Pearson’s correlation analysis. Results: At 0M, 25% of the products had pH values below the critical threshold for enamel, and 75% fell below that for dentin. The distribution of products significantly differed based on critical pH thresholds (p < 0.05). The two-way repeated-measures ANOVA showed that the pH was significantly affected by the storage time (p < 0.05), but not by the storage temperature or its interaction with time. By contrast, ORP was significantly affected by the storage temperature, storage time, and their interaction (p < 0.05). The Pearson’s correlation analysis revealed a significant negative correlation between pH and ORP at 4 °C (6M), 25 °C (1M, 3M, 6M), and 37 °C (all time points) (p < 0.05). Conclusions: Many oral moisturizers exhibit acidic pH values, indicating that products with a pH of 6.7 or higher should be selected. Additionally, to minimize degradation, oral moisturizers should be stored at 4 °C and used within 3 months of opening. Full article

Background/Objectives: The aim of this systematic review was to identify the role of orthodontics in patients undergoing tumor-ablative surgery, in collaboration with maxillofacial prosthodontic rehabilitation in a multidisciplinary fashion. Methods: This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was registered in the International Prospective Register of Systematic Reviews (PROSPERO) database (CRD42024582050). The focused question was constructed using the PICO (participant, intervention, comparison, and outcome) approach. A three-stage search was performed in PubMed, Scopus, and Web of Science using Medical Subject Heading (MeSH) terms. To assess the risk of bias, the National Institute of Health (NIH) “Quality Assessment Tool for case series/reports” was used. All data was synthesized qualitatively, according to the Synthesis Without Meta-analysis (SWiM) reporting guideline. Results: The initial search yielded 624 articles, of which 22 met the inclusion criteria after screening and eligibility assessment, with most being single-patient case reports and one case series involving 12 patients. The included studies primarily involved tumors in the mandible (64.5%) and maxilla (32.3%). Orthodontic treatment was initiated at various time points, ranging from one month pre-surgery to 19 years post-surgery, primarily utilizing fixed appliances (77.8%). In some studies, orthodontic appliances were used to enhance the stability of maxillofacial prostheses. The results of this study indicate that orthodontic treatment may facilitate prosthetic rehabilitation by improving conditions prior to prosthetic intervention and increasing the retention of the obturator prosthesis. Conclusions: Orthodontic treatment can enhance maxillofacial prosthetic rehabilitation after tumor-ablative surgery by optimizing jaw growth, improving occlusion, and facilitating prosthetic retention or space creation. Further research is needed to establish treatment guidelines. Orthodontic miniscrews may improve temporary prosthesis retention before final implant placement, when indicated. Full article

This in vitro study aims to investigate the fracture properties of 3D-printed resin provisional material designed with different connector dimensions for two-unit fixed dental prostheses (FDPs). The master model was digitally designed following Shillingburg’s all-ceramic restoration tooth preparation guidelines and milled from aluminum. Four two-unit FDPs with different connector dimensions were designed: 2 × 3 mm, 3 × 3 mm, 3 × 4 mm, and 4 × 4 mm (width × length) (Groups A, B, C, and D, respectively; n = 10 for each group). These specimens were printed using 3D-printed resin material (Detax FREEPRINT^® temp). Forty specimens were subjected to a three-point test using a universal testing machine until fracture. The failure mode was examined under a stereomicroscope. The Kruskal–Wallis test at α = 0.05 revealed non-significant differences in fracture resistance load but significantly different elastic modulus, yield strength, and compressive strength (p = 0.061, p < 0.001, p < 0.001, and p < 0.001, respectively) among the different groups. The 2 × 3 mm connectors had higher means of modulus, yield strength, and compressive strength compared to the other groups. The study found that the maximum load causing fractures in 3D-printed provisional material connectors was consistent, regardless of connector cross-section variations. The 2 × 3 mm group performed best, while the 4 × 4 mm group performed worst. Full article

Background/Objectives: Mycophenolate mofetil (MMF) has emerged as a valuable immunosuppressive agent used in the management of oral mucocutaneous diseases, particularly in autoimmune and inflammatory conditions, such as pemphigus vulgaris (PV), oral lichen planus (OLP), mucous membrane pemphigoid (MMP), systemic lupus erythematosus (SLE), erythema multiforme (EM) and recurrent aphthous stomatitis (RAS). This review consolidates the current evidence regarding MMF’s efficacy, safety and clinical applications across these conditions. Methods: A comprehensive review of literature was performed, focusing on the mechanism of action, dosing strategies, therapeutic outcomes and adverse effects associated with MMF therapy in oral mucocutaneous diseases. The potential of therapeutic drug monitoring (TDM) in optimizing MMF therapy and minimizing adverse effects was also explored. Results: The review demonstrates that MMF is effective in inducing disease remission in up to 80% of patients with PV, with notable steroid-sparing effects. In OLP, MMF provided significant clinical improvement, especially in patients with severe and refractory forms of the disease. For MMP, MMF showed an 89% response rate, particularly when combined with corticosteroids, though gastrointestinal side effects were noted in some patients. In SLE, MMF was effective in managing both renal and non-renal manifestations, with favorable remission rates observed in patients receiving MMF therapy. For EM, MMF’s effectiveness was limited, with only a small number of patients responding to therapy. In RAS, there is limited evidence of MMF’s efficacy, with only partial improvement in severe cases reported. MMF is a promising immunomodulatory therapy for oral mucocutaneous diseases, particularly in reducing corticosteroid dependence and improving patient outcomes. However, the variability in the study designs, dosages and patient populations complicates the generalization of these findings. Conclusions: There is a pressing need for randomized controlled trials to validate MMF’s efficacy and long-term safety across all disease categories. The integration of therapeutic drug monitoring (TDM) shows potential for improving disease control and minimizing adverse effects, making it a key consideration for future research. Full article

Three-dimensional (3D) printing is a cutting-edge technology that is widely used in biomedical fields to construct various commercial products or scaffolds for theoretical research. In this review, 3D printing technologies with different principles are briefly introduced, including selective laser melting (SLM), selective laser sintering (SLS), fused deposition modeling (FDM), stereolithography (SLA), and digital light processing (DLP). In addition, the applications of 3D printing in dentistry, such as dental implantology, prosthodontics, orthodontics, maxillofacial surgery, and dental tissue regeneration, were summarized. Furthermore, the perspective and challenges of 3D printing were also addressed to help the readers obtain a clear map for the development of 3D printing in dentistry. Full article

This study aims to evaluate the stress distribution of polyetheretherketone (PEEK) and high noble alloy materials in a detailed 3D model of a central incisor using finite element analysis (FEA). A comprehensive 3D model incorporated the crown, crown cement, post and core, post cement, central incisor root, periodontal ligament (PDL), and bone. The PEEK and high noble alloy material properties were input into the model, and the FEA was performed using ABAQUS software. The results showed that while the stresses on the bone, root, and crown increased slightly with the PEEK compared to the high noble alloy, the difference was minimal and attributed to the PEEK’s reduced stiffness. This led to a higher load transfer to surrounding regions around the post. The factor of safety decreased from 16 to 10 when using PEEK, but this reduction was still within acceptable limits and reduced stress-shielding effects. In conclusion, while there was no significant difference in stress magnitudes and distributions between the PEEK and high noble alloys, the PEEK exhibited superior stress-shielding properties, which may offer an advantage in preserving the underlying tooth structure in post and core restorations. Full article

This study evaluated the impact of glazing and multiple firing on the flexural strength, translucency, and color stability of three types of zirconia: 3 mol% yttria-stabilized tetragonal zirconia polycrystals (3Y-TZP), 4 mol% yttria partially stabilized zirconia (4Y-PSZ), and 5 mol% yttria partially stabilized zirconia (5Y-PSZ). A total of 120 samples were categorized into four groups: polishing only (P), polishing + glazing (PG), polishing + glazing + one glaze firing (PGF), and polishing + glazing + two glaze firings (PGFF). A three-point bending test was used for assessing flexural strength and a spectrophotometer analysis for assessing color difference (ΔE*_ab) and translucency parameter (TP). Statistical analysis included one-way ANOVA and Kruskal–Wallis tests, with significance set at α = 0.05. The type 3Y-TZP showed the highest flexural strength (918.46 MPa) and lowest translucency (TP = 4.32), while 5Y-PSZ exhibited the lowest strength (401.58 MPa, p < 0.001) and highest translucency (TP = 6.26, p ≤ 0.012). Heat treatment resulted in a significant reduction in the flexural strength of 5Y-PSZ (p = 0.002), followed by 3Y-TZP (p = 0.04). The type 5Y-PSZ exhibited significant change in translucency (p = 0.003) and unacceptable variations in color (ΔE*_ab: 1.49–9.6). The type 4Y-PSZ exhibited the highest stability in flexural strength, translucency, and color under multiple treatments. In conclusion, while glazing and firing significantly compromised 5Y-PSZ’s flexural strength and altered its color and translucency, 4Y-PSZ demonstrated the highest stability. Full article

The present study describes the case of a severe surgical complication in a 42-year-old female patient undergoing bimaxillary orthognathic surgery for the correction of skeletal class III, where a detachment of the surgical plates and fibrous healing of the palatal suture occurred. The aim of this study was to enlighten two important concepts: (I) how occlusal and mandible position changes can be well tolerated by the temporomandibular joint even in the case of a failed orthognathic surgery; (II) how a prosthodontic approach based on the search for occlusal stabilization made it possible to manage a complicated clinical case. Clinical Presentation: Clinically, the patient presented an occlusal instability and a split and mobile maxillary bone with respect to the cranial base. The case was resolved using full-mouth prosthodontic rehabilitation to fix the occlusal instability and guide maxillofacial surgeons, establishing the new occlusal position during an orthognathic reintervention. Clinical Relevance: The function was reestablished independently on any treatment planning centered on the temporomandibular joint repositioning concepts. However, although neuromuscular plasticity and the patient’s adaptation skills can explain the clinical success in such complex rehabilitations, these findings must be interpreted with caution due to the limited generalizability inherent to the study’s design. Full article

Additive manufacturing (3D printing) has transformed dentistry by providing solutions with high precision and accuracy achieved through digital workflows, which facilitate the creation of intricate and personalized structures. Additionally, 3D printing promotes cost efficiency by reducing material waste and errors while enabling on-demand production, minimizing the need for extensive inventories. Recent advancements in 3D-printed resin materials have enhanced their clinical applications by improving mechanical strength, biocompatibility, esthetics, and durability. These innovations have facilitated the fabrication of complex and patient-specific structures, such as dental prostheses, surgical guides, and orthodontic appliances, while significantly reducing production time and material waste. Ongoing research and innovation are expected to strengthen resin properties, including strength, translucency, and durability, broadening their clinical applications. The ongoing evolution of 3D printing technology is poised to play a critical role in driving personalized treatments, streamlining clinical workflows, and shaping the future of dental care. This narrative review comprehensively examines the production techniques and clinical applications of 3D-printed photopolymer resins across various dental specialties, including prosthodontics, orthodontics, pediatric dentistry, maxillofacial surgery, periodontology, endodontics, and conservative dentistry. Additionally, the review provides insight into the transformative impact of these technologies on patient care, highlights existing challenges, and suggests future directions for advancing resin properties and their integration into routine dental practice. Full article

Artificial intelligence (AI) is an area of computer science that focuses on designing machines or systems that can perform operations that would typically need human intelligence. AI is a rapidly developing technology that has grabbed the interest of researchers from all across the globe in the healthcare industry. Advancements in machine learning and data analysis have revolutionized oral health diagnosis, treatment, and management, making it a transformative force in healthcare, particularly in dentistry. Particularly in dentistry, AI is becoming increasingly prevalent as it contributes to the diagnosis of oro-facial diseases, offers treatment modalities, and manages practice in the dental operatory. All dental disciplines, including oral medicine, operative dentistry, pediatric dentistry, periodontology, orthodontics, oral and maxillofacial surgery, prosthodontics, and forensic odontology, have adopted AI. The majority of AI applications in dentistry are for diagnoses based on radiographic or optical images, while other tasks are less applicable due to constraints such as data availability, uniformity, and computational power. Evidence-based dentistry is considered the gold standard for decision making by dental professionals, while AI machine learning models learn from human expertise. Dentistry AI and technology systems can provide numerous benefits, such as improved diagnosis accuracy and increased administrative task efficiency. Dental practices are already implementing various AI applications, such as imaging and diagnosis, treatment planning, robotics and automation, augmented and virtual reality, data analysis and predictive analytics, and administrative support. The dentistry field has extensively used artificial intelligence to assist less-skilled practitioners in reaching a more precise diagnosis. These AI models effectively recognize and classify patients with various oro-facial problems into different risk categories, both individually and on a group basis. The objective of this descriptive review is to review the most recent developments of AI in the field of dentistry. Full article

This study investigates the impact of tightening torque (preload) and the friction coefficient on stress generation and fatigue resistance of a Ti-6Al-4V abutment screw with an internal hexagonal connection under dynamic multi-axial masticatory loads in high-cycle fatigue (HCF) conditions. A three-dimensional model of the implant–abutment assembly was simulated using ANSYS Workbench 16.2 computer aided engineering software with chewing forces ranging from 300 N to 1000 N, evaluated over 1.35 × 10⁷ cycles, simulating 15 years of service. Results indicate that the healthy range of normal to maximal mastication forces (300–550 N) preserved the screw’s structural integrity, while higher loads (≥800 N) exceeded the Ti-6Al-4V alloy’s yield strength, indicating a risk of plastic deformation under extreme conditions. Stress peaked near the end of the occluding phase (206.5 ms), marking a critical temporal point for fatigue accumulation. Optimizing the friction coefficient (0.5 µ) and preload management improved stress distribution, minimized fatigue damage, and ensured joint stability. Masticatory forces up to 550 N were well within the abutment screw’s capacity to sustain extended service life and maintain its elastic behavior. Full article

Background: The present study evaluated the histological outcomes of two dental restorative materials, polyacid-modified composite resin (compomer) and conventional composite resin, in the primary molars of puppies. Materials and Methods: Twenty sound primary molars in four puppies were used. The puppies were rendered unconscious using general anesthesia. Similar cylindrical Class V cavities were prepared in 16 of the 20 selected primary molars. The teeth were divided into three groups: Group I: Eight cavities were restored with compomer; Group II: Eight cavities were restored with conventional composite resin; Group III: Four teeth remained untreated and were used as controls. In Groups I and II, four teeth were examined histologically after 2 weeks and the other four after 6 weeks. The histological findings were analyzed and compared to determine the effects of each type of resin material on the dentine and the pulp. Results: At 6 weeks, the specimens tested for compomer showed obvious destructive changes in the central region and the region of the pulp adjacent to the cavity. The specimens tested for conventional composite resin revealed, at 6 weeks, massive destruction of the pulp tissues and abscess formation was observed. All the specimens tested in the control group showed normal cellularity, normal vascularity, and proper alignment of odontoblast cells. Conclusions: The teeth restored with compomer demonstrated more favorable pulpal reactions when compared with the teeth restored with conventional composite resin after 6 weeks. Full article

As the discipline of prosthodontics evolves, it encounters a dynamic landscape characterized by innovation and improvement. This comprehensive analysis underscores future developments and transformative solutions across its various subspecialties: fixed, removable, implant, and maxillofacial prosthodontics. The narrative review examines the latest advancements in prosthetic technology, focusing on several critical areas. The integration of artificial intelligence and machine learning into prosthetic design and fitting processes is revolutionizing the field, serving as a common thread that links these innovative technologies across all subspecialties. This includes advancements in automated diagnostics, predictive analysis, and treatment planning. Furthermore, the review offers a forward-looking perspective on how these innovations are influencing each prosthetic dentistry domain, patient outcomes, and current clinical practices. By thoroughly analyzing contemporary research and emerging technologies, the study illustrates how these advancements represent a growing focal point of interest in developing countries, such as Romania, with the potential to redefine the trajectory of prosthetic rehabilitation and enhance patient care not only within this country but also beyond. Full article

The literature presents insufficient data evaluating the displacement and micromotion effects resulting from the combined use of tooth-implant connections in fixed partial dentures. Analyzing the biomechanical behavior of tooth-implant fixed partial denture (FPD) prothesis is vital for achieving an optimum design and successful clinical implementation. The objective of this study was to determine the relative significance of connector design on the displacement and micromotion of tooth-implant-supported fixed dental prostheses under occlusal vertical loading. A unilateral Kennedy class I mandibular model was created using a 3D reconstruction from CT scan data. Eight simulated designs of tooth-implant fixed partial dentures (FPDs) were split into two groups: Group A with rigid connectors and Group B with non-rigid connectors. The models were subjected to a uniform vertical load of 100 N. Displacement, strain, and stress were computed using finite element analysis. The materials were defined as isotropic, homogeneous, and exhibiting linear elastic properties. This study focused on assessing the maximum displacement in various components, including the bridge, mandible, dentin, cementum, periodontal ligament (PDL), and implant. Displacement values were predominantly higher in Group B (non-rigid) compared to Group A (rigid) in all measured components of the tooth-implant FPDs. Accordingly, a statistically significant difference was observed between the two groups at the FPD bridge (p value = 0.021 *), mandible (p value = 0.021 *), dentin (p value = 0.043 *), cementum (p value = 0.043 *), and PDL (p value = 0.043 *). Meanwhile, there was an insignificant increase in displacement values recorded in the distal implant (p value = 0.083). This study highlighted the importance of connector design in the overall stability and performance of the prosthesis. Notably, the 4.7 mm × 10 mm implant in Group B showed a displacement nearly 92 times higher than its rigid counterpart in Group A. Overall, the 5.7 mm × 10 mm combination of implant length and diameter showcased the best performance in both groups. The findings demonstrate that wider implants with a proportional length offer greater resistance to displacement forces. In addition, the use of rigid connection design provides superior biomechanical performance in tooth-implant fixed partial dentures and reduces the risk of micromotion with its associated complications such as ligament overstretching and implant overload, achieving predictable prognosis and enhancing the stability of the protheses. Full article

The newest technology allows the medical industry to manufacture innovative products such as milled titanium prosthodontic parts in an implant for a screw-retained suprastructure. In the literature, there are some articles on the clinical usage of subperiosteal implants, but none of these publications, either in PubMed or Google Scholar, thoroughly describe the workflow for the design and manufacture of individual implants for maxillofacial surgery with milled threads for a screw-retained prosthodontic bridge. The aim of the article is to present a step-by-step method of producing personalized implants, from the first steps of production to the implantation of the final product. The article includes information on patient qualification for surgery, computational preparation and skull printing, planning of Mai Implants^®, meshing, 3D printing and milling, cleaning, rinsing, anodizing, and laser marking, as well as the cleaning and sterilization process in a hospital or dental clinic. A detailed description of implant production allows for the analysis of each step and the development of technology. The production of implants is an expensive procedure, but considering all the advantages of the Mai Implants^® treatment and the disadvantages of alternatives, the product is worth the price. Full article