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  • Article
  • Open Access
33 Citations
5,038 Views
16 Pages

Protective Effects of a Lutein Ester Prodrug, Lutein Diglutaric Acid, against H2O2-Induced Oxidative Stress in Human Retinal Pigment Epithelial Cells

  • Chawanphat Muangnoi,
  • Rianthong Phumsuay,
  • Nattapong Jongjitphisut,
  • Pasin Waikasikorn,
  • Monsin Sangsawat,
  • Paitoon Rashatasakhon,
  • Luminita Paraoan and
  • Pornchai Rojsitthisak

Oxidative stress-induced cell damage and death of the retinal pigmented epithelium (RPE), a polarized monolayer that maintains retinal health and homeostasis, lead to the development of age-related macular degeneration (AMD). Several studies show tha...