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17 pages, 1909 KiB  
Article
Ergonomics Study of Musculoskeletal Disorders Among Tram Drivers
by Jasna Leder Horina, Jasna Blašković Zavada, Marko Slavulj and Damir Budimir
Appl. Sci. 2025, 15(15), 8348; https://doi.org/10.3390/app15158348 - 27 Jul 2025
Viewed by 336
Abstract
Work-related musculoskeletal disorders (WMSDs) are among the most prevalent occupational health issues, particularly affecting public transport drivers due to prolonged sitting, constrained postures, and poorly adaptable cabins. This study addresses the ergonomic risks associated with tram driving, aiming to evaluate biomechanical load and [...] Read more.
Work-related musculoskeletal disorders (WMSDs) are among the most prevalent occupational health issues, particularly affecting public transport drivers due to prolonged sitting, constrained postures, and poorly adaptable cabins. This study addresses the ergonomic risks associated with tram driving, aiming to evaluate biomechanical load and postural stress in relation to drivers’ anthropometric characteristics. A combined methodological approach was applied, integrating two standardized observational tools—RULA and REBA—with anthropometric modeling based on three representatives European morphotypes (SmallW, MidM, and TallM). ErgoFellow 3.0 software was used for digital posture evaluation, and lumbar moments at the L4/L5 vertebral level were calculated to estimate lumbar loading. The analysis was simulation-based, using digital human models, and no real subjects were involved. The results revealed uniform REBA (Rapid Entire Body Assessment) and RULA (Rapid Upper Limb Assessment) scores of 6 across all morphotypes, indicating moderate to high risk and a need for ergonomic intervention. Lumbar moments ranged from 51.35 Nm (SmallW) to 101.67 Nm (TallM), with the tallest model slightly exceeding the recommended ergonomic thresholds. These findings highlight a systemic mismatch between cabin design and user variability. In conclusion, ergonomic improvements such as adjustable seating, better control layout, and driver education are essential to reduce the risk of WMSDs. The study proposes a replicable methodology combining anthropometric, observational, and biomechanical tools for evaluating and improving transport workstation design. Full article
(This article belongs to the Section Applied Biosciences and Bioengineering)
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31 pages, 5858 KiB  
Article
Research on Optimization of Indoor Layout of Homestay for Elderly Group Based on Gait Parameters and Spatial Risk Factors Under Background of Cultural and Tourism Integration
by Tianyi Yao, Bo Jiang, Lin Zhao, Wenli Chen, Yi Sang, Ziting Jia, Zilin Wang and Minghu Zhong
Buildings 2025, 15(14), 2498; https://doi.org/10.3390/buildings15142498 - 16 Jul 2025
Viewed by 183
Abstract
This study, in response to the optimization needs of fall risks for the elderly in the context of cultural and tourism integration in Hebei Province, China, established a quantitative correlation system between ten gait parameters and ten types of spatial risk factors. By [...] Read more.
This study, in response to the optimization needs of fall risks for the elderly in the context of cultural and tourism integration in Hebei Province, China, established a quantitative correlation system between ten gait parameters and ten types of spatial risk factors. By collecting gait data (Qualisys infrared motion capture system, sampling rate 200 Hz) and spatial parameters from 30 elderly subjects (with mild, moderate, and severe functional impairments), a multi-level regression model was established. This study revealed that step frequency, step width, and step length were nonlinearly associated with corridor length, door opening width, and step depth (R2 = 0.53–0.68). Step speed, ankle dorsiflexion, and foot pressure were key predictive factors (OR = 0.04–8.58, p < 0.001), driving the optimization of core spatial factors such as threshold height, handrail density, and friction coefficient. Step length, cycle, knee angle, and lumbar moment, respectively, affected bed height (45–60 cm), switch height (1.2–1.4 m), stair riser height (≤35 mm), and sink height adjustment range (0.7–0.9 m). The prediction accuracy of the ten optimized values reached 86.7% (95% CI: 82.1–90.3%), with Hosmer–Lemeshow goodness-of-fit x2 = 7.32 (p = 0.412) and ROC curve AUC = 0.912. Empirical evidence shows that the graded optimization scheme reduced the fall risk by 42–85%, and the estimated fall incidence rate decreased by 67% after the renovation. The study of the “abnormal gait—spatial threshold—graded optimization” quantitative residential layout optimization provides a systematic solution for the data-quantified model of elderly-friendly residential renovations. Full article
(This article belongs to the Section Architectural Design, Urban Science, and Real Estate)
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21 pages, 7110 KiB  
Article
Impact of Contralateral Hemiplegia on Lower Limb Joint Kinematics and Dynamics: A Musculoskeletal Modeling Approach
by Sadia Younis, Alka Bishnoi, Jyotindra Narayan and Renato Mio
Biomechanics 2024, 4(4), 784-804; https://doi.org/10.3390/biomechanics4040058 - 18 Dec 2024
Viewed by 965
Abstract
This study investigates the biomechanical differences between typically developed (TD) individuals and those with contralateral hemiplegia (CH) using musculoskeletal modeling in OpenSim. Ten TD participants and ten CH patients were analyzed for joint angles and external joint moments around the three anatomical axes: [...] Read more.
This study investigates the biomechanical differences between typically developed (TD) individuals and those with contralateral hemiplegia (CH) using musculoskeletal modeling in OpenSim. Ten TD participants and ten CH patients were analyzed for joint angles and external joint moments around the three anatomical axes: frontal, sagittal, and transverse. The analysis focused on hip, pelvis, lumbar, knee, ankle, and subtalar joint movements, leveraging MRI-derived bone length data and gait analysis. Significant differences (p < 0.05) were observed in hip flexion, pelvis tilt, lumbar extension, and ankle joint angles, highlighting the impact of hemiplegia on these specific joints. However, parameters like hip adduction and rotation, knee moment, and subtalar joint dynamics did not show significant differences, with p > 0.05. The comparison of joint angle and joint moment correlations between TD and CH participants highlights diverse coordination patterns in CH. Joint angles show significant shifts, such as HF and LR (−0.35 to −0.97) and PR and LR (0.22 to −0.78), reflecting disrupted interactions, while others like HR and LR (0.42 to 0.75) exhibit stronger coupling in CH individuals. Joint moments remain mostly stable, with HF and HA (0.54 to 0.53) and PR and LR (−0.51 to −0.50) showing negligible changes. However, some moments, like KA and HF (0.11 to −0.13) and PT and KA (0.75 to 0.67), reveal weakened or altered relationships. These findings underscore biomechanical adaptations and compensatory strategies in CH patients, affecting joint coordination. Overall, CH individuals exhibit stronger negative correlations, reflecting impaired coordination. These findings provide insight into the musculoskeletal alterations in hemiplegic patients, potentially guiding the development of targeted rehabilitation strategies. Full article
(This article belongs to the Special Issue Personalized Biomechanics and Orthopedics of the Lower Extremity)
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14 pages, 1431 KiB  
Article
Impact of Diaphragm-Strengthening Core Training on Postural Stability in High-Intensity Squats
by Hyun Seo, Guyeol Jeong and Buongo Chun
Life 2024, 14(12), 1612; https://doi.org/10.3390/life14121612 - 5 Dec 2024
Cited by 2 | Viewed by 2849
Abstract
This study analyzed the effects of an 8-week diaphragmatic core training program on postural stability during high-intensity squats and examined its efficacy in injury prevention and performance enhancement. Thirty-seven male participants were randomly assigned to three groups: diaphragmatic core training group (DCTG, n [...] Read more.
This study analyzed the effects of an 8-week diaphragmatic core training program on postural stability during high-intensity squats and examined its efficacy in injury prevention and performance enhancement. Thirty-seven male participants were randomly assigned to three groups: diaphragmatic core training group (DCTG, n = 12), core training group (CTG, n = 13), and control group (CG, n = 12). Outcome measurements included diaphragm thickness, respiratory function (mean and maximal respiratory pressures), and squat postural stability (distance between the sacral and upper body center points, peak trunk extension moment, peak knee flexion moment, and dynamic postural stability index). Compared to both CTG and CG, DCTG demonstrated significantly greater improvements in diaphragm thickness (DCTG: 34.62% increase vs. CTG: 1.36% and CG: 3.62%, p < 0.001), mean respiratory pressure (DCTG: 18.88% vs. CTG: 1.31% and CG: 0.02%, p < 0.001), and maximal respiratory pressure (DCTG: 18.62% vs. CTG: 0.72% and CG: 1.90%, p < 0.001). DCTG also showed superior improvements in postural stability measures, including reductions in the distance between sacral and upper body center points (DCTG: −6.19% vs. CTG: −3.26% and CG: +4.55%, p < 0.05), peak trunk extension moment (DCTG: −15.22% vs. CTG: −5.29% and CG: +19.31%, p < 0.001), and dynamic postural stability index (DCTG: −28.13% vs. CTG: −21.43% and CG: no change, p < 0.001). No significant between-group differences were observed in peak knee flexion moment. Core training incorporating diaphragmatic strengthening was more effective than conventional training in improving postural stability during high-intensity squats. Core training programs, including diaphragmatic strengthening exercises, may contribute to injury prevention and performance enhancement in exercises requiring lumbar stability, such as squats. Full article
(This article belongs to the Special Issue Resistance Training Is Medicine)
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15 pages, 1608 KiB  
Article
Age-Related Differences in the Functional Demand Placed on the Lumbar Spine during Walking in Healthy Older versus Younger Men
by Alexander Dallaway, Michael Duncan, Corbin Griffen, Derek Renshaw, Jason Tallis and John Hattersley
Geriatrics 2024, 9(5), 108; https://doi.org/10.3390/geriatrics9050108 - 23 Aug 2024
Cited by 1 | Viewed by 1631
Abstract
Age-related declines in the musculoskeletal system may place additional demands on the lumbar spine during everyday activities such as walking. This study aimed to investigate age-related differences in the functional demand (FD) of walking on the lumbar spine in older and younger adults. [...] Read more.
Age-related declines in the musculoskeletal system may place additional demands on the lumbar spine during everyday activities such as walking. This study aimed to investigate age-related differences in the functional demand (FD) of walking on the lumbar spine in older and younger adults. A motion analysis system with integrated force plates was used to acquire kinematic and kinetic data on 12 older (67.3 ± 6.0 years) and 12 younger (24.7 ± 3.1 years) healthy men during walking at a self-selected speed along a 10 m walkway. Isokinetic dynamometry was used to acquire the maximal joint moment capacity of the lumbar spine. The FD of the lumbar spine was calculated as the muscle moment during key phases of the gait cycle (GC) relative to the maximum moment capacity of the lumbar spine. The difference in FD between age groups was not significant (p = 0.07) and there were no significant differences between the young group (YG) and older group (OG) for any individual phase in the GC. Despite the lack of statistical significance, the results indicate that a practical difference may exist, as walking was approximately 20% more functionally demanding on the lumbar spine in the OG compared to the YG. Therefore, older adults may employ modified gait strategies to reduce mechanical load whilst walking to fall within the limits of their maximal force-producing capacity in the lumbar spine, which may have implications for injury risk. Full article
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16 pages, 3418 KiB  
Article
Biomechanical Study of Symmetric Bending and Lifting Behavior in Weightlifter with Lumbar L4-L5 Disc Herniation and Physiological Straightening Using Finite Element Simulation
by Caiting Zhang, Yang Song, Qiaolin Zhang, Ee-Chon Teo and Wei Liu
Bioengineering 2024, 11(8), 825; https://doi.org/10.3390/bioengineering11080825 - 12 Aug 2024
Cited by 1 | Viewed by 2882
Abstract
Background: Physiological curvature changes of the lumbar spine and disc herniation can cause abnormal biomechanical responses of the lumbar spine. Finite element (FE) studies on special weightlifter models are limited, yet understanding stress in damaged lumbar spines is crucial for preventing and rehabilitating [...] Read more.
Background: Physiological curvature changes of the lumbar spine and disc herniation can cause abnormal biomechanical responses of the lumbar spine. Finite element (FE) studies on special weightlifter models are limited, yet understanding stress in damaged lumbar spines is crucial for preventing and rehabilitating lumbar diseases. This study analyzes the biomechanical responses of a weightlifter with lumbar straightening and L4-L5 disc herniation during symmetric bending and lifting to optimize training and rehabilitation. Methods: Based on the weightlifter’s computed tomography (CT) data, an FE lumbar spine model (L1-L5) was established. The model included normal intervertebral discs (IVDs), vertebral endplates, ligaments, and a degenerated L4-L5 disc. The bending angle was set to 45°, and weights of 15 kg, 20 kg, and 25 kg were used. The flexion moment for lifting these weights was theoretically calculated. The model was tilted at 45° in Abaqus 2021 (Dassault Systèmes Simulia Corp., Johnston, RI, USA), with L5 constrained in all six degrees of freedom. A vertical load equivalent to the weightlifter’s body mass and the calculated flexion moments were applied to L1 to simulate the weightlifter’s bending and lifting behavior. Biomechanical responses within the lumbar spine were then analyzed. Results: The displacement and range of motion (ROM) of the lumbar spine were similar under all three loading conditions. The flexion degree increased with the load, while extension remained unchanged. Right-side movement and bending showed minimal change, with slightly more right rotation. Stress distribution trends were similar across loads, primarily concentrated in the vertebral body, increasing with load. Maximum stress occurred at the anterior inferior margin of L5, with significant stress at the posterior joints, ligaments, and spinous processes. The posterior L5 and margins of L1 and L5 experienced high stress. The degenerated L4-L5 IVD showed stress concentration on its edges, with significant stress also on L3-L4 IVD. Stress distribution in the lumbar spine was uneven. Conclusions: Our findings highlight the impact on spinal biomechanics and suggest reducing anisotropic loading and being cautious of loaded flexion positions affecting posterior joints, IVDs, and vertebrae. This study offers valuable insights for the rehabilitation and treatment of similar patients. Full article
(This article belongs to the Special Issue Advances in Trauma and Injury Biomechanics)
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24 pages, 395 KiB  
Article
Lumbar Paravertebral Muscle Pain Management Using Kinesitherapy and Electrotherapeutic Modalities
by Sînziana Călina Silişteanu, Elisabeta Antonescu, Lavinia Duică, Maria Totan, Andrei Ionuţ Cucu and Andrei Ioan Costea
Healthcare 2024, 12(8), 853; https://doi.org/10.3390/healthcare12080853 - 18 Apr 2024
Cited by 2 | Viewed by 3057
Abstract
Background: Low back pain is considered a public health problem internationally. Low back pain is a cause of disability that occurs in adolescents and causes negative effects in adults as well. The work environment and physical and psychosocial factors can influence the occurrence [...] Read more.
Background: Low back pain is considered a public health problem internationally. Low back pain is a cause of disability that occurs in adolescents and causes negative effects in adults as well. The work environment and physical and psychosocial factors can influence the occurrence and evolution of low back pain. Methods: The purpose of this paper is to highlight the physiological and functional changes in young adults with painful conditions of the lumbar spine, after using exercise therapy. The study was of the longitudinal type and was carried out over a period 6 months in an outpatient setting. The rehabilitation treatment included electrotherapeutic modalities and kinesitherapy. Results: The results obtained when evaluating each parameter, for all moments, show statistically significant values in both groups. The results obtained regarding the relationship between the therapeutic modalities specific to rehabilitation medicine and low back pain are consistent with those reported in studies. Conclusions: Depending on the clinical-functional status of each patient, kinesitherapy can accelerate the heart rate and increase the blood pressure and oxygen saturation of the arterial blood, values that can later return to their initial levels, especially through training. Full article
(This article belongs to the Special Issue The 10th Anniversary of Healthcare—Pain Management)
17 pages, 7125 KiB  
Article
Pelvic Ring Fractures: A Biomechanical Comparison of Sacral and Lumbopelvic Fixation Techniques
by Sudharshan Tripathi, Norihiro Nishida, Sophia Soehnlen, Amey Kelkar, Yogesh Kumaran, Toshihiro Seki, Takashi Sakai and Vijay K. Goel
Bioengineering 2024, 11(4), 348; https://doi.org/10.3390/bioengineering11040348 - 2 Apr 2024
Cited by 2 | Viewed by 2214
Abstract
Background Context: Pelvic ring fractures are becoming more common in the aging population and can prove to be fatal, having mortality rates between 10% and 16%. Stabilization of these fractures is challenging and often require immediate internal fixation. Therefore, it is necessary to [...] Read more.
Background Context: Pelvic ring fractures are becoming more common in the aging population and can prove to be fatal, having mortality rates between 10% and 16%. Stabilization of these fractures is challenging and often require immediate internal fixation. Therefore, it is necessary to have a biomechanical understanding of the different fixation techniques for pelvic ring fractures. Methods: A previously validated three-dimensional finite element model of the lumbar spine, pelvis, and femur was used for this study. A unilateral pelvic ring fracture was simulated by resecting the left side of the sacrum and pelvis. Five different fixation techniques were used to stabilize the fracture. A compressive follower load and pure moment was applied to compare different biomechanical parameters including range of motion (contralateral sacroiliac joint, L1-S1 segment, L5-S1 segment), and stresses (L5-S1 nucleus stresses, instrument stresses) between different fixation techniques. Results: Trans-iliac–trans-sacral screw fixation at S1 and S2 showed the highest stabilization for horizontal and vertical displacement at the sacral fracture site and reduction of contralateral sacroiliac joint for bending and flexion range of motion by 165% and 121%, respectively. DTSF (Double transiliac rod and screw fixation) model showed highest stabilization in horizontal displacement at the pubic rami fracture site, while the L5_PF_W_CC (L5-Ilium posterior screw fixation with cross connectors) and L5_PF_WO_CC (L5-Ilium posterior screw fixation without cross connectors) showed higher rod stresses, reduced L1-S1 (approximately 28%), and L5-S1 (approximately 90%) range of motion. Conclusions: Longer sacral screw fixations were superior in stabilizing sacral and contralateral sacroiliac joint range of motion. Lumbopelvic fixations displayed a higher degree of stabilization in the horizontal displacement compared to vertical displacement of pubic rami fracture, while also indicating the highest rod stresses. When determining the surgical approach for pelvic ring fractures, patient-specific factors should be accounted for to weigh the advantages and disadvantages for each technique. Full article
(This article belongs to the Special Issue Advances in Trauma and Injury Biomechanics)
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15 pages, 3516 KiB  
Article
Can Pressure Data from Wearable Insole Devices Be Utilized to Estimate Low Back Moments for Exoskeleton Control System?
by Seungheon Chae, Ahnryul Choi, Jeehae Kang and Joung Hwan Mun
Actuators 2024, 13(3), 92; https://doi.org/10.3390/act13030092 - 27 Feb 2024
Cited by 1 | Viewed by 1972
Abstract
This study presents a machine learning model for predicting lumbar spine moments using data from low-cost sensors, with the ultimate aim of developing a control strategy for waist-active exoskeleton devices. The limitation of sparse features in low-cost insoles was addressed by leveraging a [...] Read more.
This study presents a machine learning model for predicting lumbar spine moments using data from low-cost sensors, with the ultimate aim of developing a control strategy for waist-active exoskeleton devices. The limitation of sparse features in low-cost insoles was addressed by leveraging a source model constructed based on data acquired from the high-precision Pedar-X device, employing a transfer learning technique. The model’s performance saw significant improvement through a training approach that incorporated high-precision commercial insole data and fine-tuning with low-cost insole data. In comparison to the conventional model, this method resulted in a noteworthy 7% enhancement in performance, achieving an rRMSE of approximately 12% and a correlation coefficient of 0.9 in lumbar joint moment prediction. If the model can demonstrate real-time efficacy and effectiveness across various operations in future applications, it holds substantial potential for deployment as an active exoskeleton device for the waist. Full article
(This article belongs to the Section Control Systems)
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16 pages, 2824 KiB  
Article
Inter-Specimen Analysis of Diverse Finite Element Models of the Lumbar Spine
by James Doulgeris, Maohua Lin, William Lee, Kamran Aghayev, Ioannis Dimitri Papanastassiou, Chi-Tay Tsai and Frank D. Vrionis
Bioengineering 2024, 11(1), 24; https://doi.org/10.3390/bioengineering11010024 - 26 Dec 2023
Cited by 3 | Viewed by 2202
Abstract
Over the past few decades, there has been a growing popularity in utilizing finite element analysis to study the spine. However, most current studies tend to use one specimen for their models. This research aimed to validate multiple finite element models by comparing [...] Read more.
Over the past few decades, there has been a growing popularity in utilizing finite element analysis to study the spine. However, most current studies tend to use one specimen for their models. This research aimed to validate multiple finite element models by comparing them with data from in vivo experiments and other existing finite element studies. Additionally, this study sought to analyze the data based on the gender and age of the specimens. For this study, eight lumbar spine (L2–L5) finite element models were developed. These models were then subjected to finite element analysis to simulate the six fundamental motions. CT scans were obtained from a total of eight individuals, four males and four females, ranging in age from forty-four (44) to seventy-three (73) years old. The CT scans were preprocessed and used to construct finite element models that accurately emulated the motions of flexion, extension, lateral bending, and axial rotation. Preloads and moments were applied to the models to replicate physiological loading conditions. This study focused on analyzing various parameters such as vertebral rotation, facet forces, and intradiscal pressure in all loading directions. The obtained data were then compared with the results of other finite element analyses and in vivo experimental measurements found in the existing literature to ensure their validity. This study successfully validated the intervertebral rotation, intradiscal pressure, and facet force results by comparing them with previous research findings. Notably, this study concluded that gender did not have a significant impact on the results. However, the results did highlight the importance of age as a critical variable when modeling the lumbar spine. Full article
(This article belongs to the Special Issue Computational Biomechanics, Volume II)
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13 pages, 4021 KiB  
Article
An Integrated Approach for Designing and Analyzing Lumbar Vertebral Biomodels with Artificial Disc Replacement
by Mhd Ayham Darwich, Katreen Ebrahem, Maysaa Shash, Hasan Mhd Nazha, Szabolcs Szávai, Yicha Zhang and Daniel Juhre
Appl. Mech. 2023, 4(4), 1227-1239; https://doi.org/10.3390/applmech4040063 - 8 Dec 2023
Cited by 1 | Viewed by 3910
Abstract
This study aims to develop an integrated approach for 3D lumbar vertebral biomodel design and analysis, specifically targeting unilevel disc degeneration and the replacement of lumbar artificial discs. Key objectives include improving existing design methods through 3D techniques, inverse modeling, and an engineering [...] Read more.
This study aims to develop an integrated approach for 3D lumbar vertebral biomodel design and analysis, specifically targeting unilevel disc degeneration and the replacement of lumbar artificial discs. Key objectives include improving existing design methods through 3D techniques, inverse modeling, and an engineering biomodel preparation protocol. Additionally, the study evaluates mechanical properties in the implantation area and between disc components to gauge the effectiveness of artificial discs in restoring functional movement within the studied biological model. The construction of a biological model representing the L3–L4 functional spinal unit was based on measurements from radiographic images and computed tomography data obtained from the study sample. The 3D finite element method in Ansys software (v. 19.2, ANSYS, Inc., Canonsburg, PA, USA) was used to monitor the distribution of equivalent stress values within the core of the two artificial discs and the behavior of vertebral bone components in the model. This approach enabled the creation of personalized digital models tailored to the specific implantation requirements of each patient. Stress analysis identified critical areas within the disc cores, suggesting potential design modifications to optimize artificial disc performance, such as selectively increasing core thickness in specific regions and considering adjustments during implantation. For example, preserving part of the lateral annulus fibrosus from the degenerative disc and maintaining the anterior and posterior longitudinal ligaments may play a crucial role in balancing the forces and moments experienced by the lumbar section. This study provides valuable insights into the development of patient-specific solutions for lumbar disc degeneration cases, with the potential for enhancing artificial disc design and implantation techniques for improved functional outcomes. Full article
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19 pages, 2380 KiB  
Systematic Review
Effects of Exercise and Sports Intervention and the Involvement Level on the Mineral Health of Different Bone Sites in the Leg, Hip, and Spine: A Systematic Review and Meta-Analysis
by Thiago P. Oliveira, Mário C. Espada, Danilo A. Massini, Ricardo A. M. Robalo, Tiago A. F. Almeida, Víctor Hernández-Beltrán, José M. Gamonales, Eliane A. Castro and Dalton M. Pessôa Filho
Int. J. Environ. Res. Public Health 2023, 20(15), 6537; https://doi.org/10.3390/ijerph20156537 - 7 Aug 2023
Cited by 9 | Viewed by 4139
Abstract
The current study analysed whether the osteogenic stimuli of exercises and sports have an independent effect on bone mineral density (BMD). Studies with a design having two different cohorts were searched and selected to distinguish the effect due to long-term involvement (i.e., athletes [...] Read more.
The current study analysed whether the osteogenic stimuli of exercises and sports have an independent effect on bone mineral density (BMD). Studies with a design having two different cohorts were searched and selected to distinguish the effect due to long-term involvement (i.e., athletes vs. non-active young with good bone health) and due to the planning of intervention (i.e., pre- vs. post-training) with exercises and sports. Moreover, only studies investigating the bone sites with a body-weight support function (i.e., lower limb, hip, and spine regions) were reviewed, since the osteogenic effects have incongruous results. A meta-analysis was performed following the recommendations of PRISMA. Heterogeneity (I2) was determined by combining Cochran’s Q test with the Higgins test, with a significance level of α = 0.05. The studies reporting the effect of involvement in exercise and sports showed high heterogeneity for the lower limb, total hip, and spine (I2 = 90.200%, 93.334%, and 95.168%, respectively, with p < 0.01) and the effect size on sports modalities (Hedge’s g = 1.529, 1.652, and 0.417, respectively, with p < 0.05) ranging from moderate to high. In turn, the studies reporting the effect of the intervention planning showed that there was no heterogeneity for the lower limb (I2 = 0.000%, p = 0.999) and spine (I2 = 77.863%, p = 0.000); however, for the hip, it was moderate (I2 = 49.432%, p = 0.054), with a low effect between the pre- and post-training moments presented only for the hip and spine (Hedge’s g = 0.313 and 0.353, respectively, with p < 0.05). The current analysis supported the effect of involvement in exercise and sports by evidencing the effect of either weight-bearing or non-weight-bearing movements on BMD at the femoral, pelvic, and lumbar bones sites of the athletes when comparing to non-athletes or non-active peers with healthy bones. Moreover, the effect of different exercise and sports interventions highlighted the alterations in the BMD in the spine bone sites, mainly with long-term protocols (~12 months) planned with a stimulus with high muscle tension. Therefore, exercise and sport (mainly systematic long-term practice) have the potential to increase the BMD of bones with body-weight support beyond the healthy values reached during life phases of youth and adulthood. Full article
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16 pages, 5753 KiB  
Article
Biomechanical Load of Neck and Lumbar Joints in Open-Surgery Training
by Ce Zhang, Charlotte Christina Roossien, Gijsbertus Jacob Verkerke, Han Houdijk, Juha M. Hijmans and Christian Greve
Sensors 2023, 23(15), 6974; https://doi.org/10.3390/s23156974 - 5 Aug 2023
Cited by 6 | Viewed by 2317
Abstract
The prevalence of musculoskeletal symptoms (MSS) like neck and back pain is high among open-surgery surgeons. Prolonged working in the same posture and unfavourable postures are biomechanical risk factors for developing MSS. Ergonomic devices such as exoskeletons are possible solutions that can reduce [...] Read more.
The prevalence of musculoskeletal symptoms (MSS) like neck and back pain is high among open-surgery surgeons. Prolonged working in the same posture and unfavourable postures are biomechanical risk factors for developing MSS. Ergonomic devices such as exoskeletons are possible solutions that can reduce muscle and joint load. To design effective exoskeletons for surgeons, one needs to quantify which neck and trunk postures are seen and how much support during actual surgery is required. Hence, this study aimed to establish the biomechanical profile of neck and trunk postures and neck and lumbar joint loads during open surgery (training). Eight surgical trainees volunteered to participate in this research. Neck and trunk segment orientations were recorded using an inertial measurement unit (IMU) system during open surgery (training). Neck and lumbar joint kinematics, joint moments and compression forces were computed using OpenSim modelling software and a musculoskeletal model. Histograms were used to illustrate the joint angle and load distribution of the neck and lumbar joints over time. During open surgery, the neck flexion angle was 71.6% of the total duration in the range of 10~40 degrees, and lumbar flexion was 68.9% of the duration in the range of 10~30 degrees. The normalized neck and lumbar flexion moments were 53.8% and 35.5% of the time in the range of 0.04~0.06 Nm/kg and 0.4~0.6 Nm/kg, respectively. Furthermore, the neck and lumbar compression forces were 32.9% and 38.2% of the time in the range of 2.0~2.5 N/kg and 15~20 N/kg, respectively. In contrast to exoskeletons used for heavy lifting tasks, exoskeletons designed for surgeons exhibit lower support torque requirements while additional degrees of freedom (DOF) are needed to accommodate combinations of neck and trunk postures. Full article
(This article belongs to the Special Issue IMU Sensors for Human Activity Monitoring)
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11 pages, 6994 KiB  
Article
Low- and Negative-Pressure Hydrocephalus: New Report of Six Cases and Literature Review
by Alicia Godoy Hurtado, Patrick Barstchi, Juan Francisco Brea Salvago, Rajab Al-Ghanem, Jose Manuel Galicia Bulnes and Osamah El Rubaidi
J. Clin. Med. 2023, 12(12), 4112; https://doi.org/10.3390/jcm12124112 - 18 Jun 2023
Cited by 7 | Viewed by 4255 | Correction
Abstract
Low- or very-low-pressure hydrocephalus is a serious and rare phenomenon, which is becoming better known since it was first described in 1994 by Pang and Altschuler. Forced drainage at negative pressures can, in most cases, restore the ventricles to their original size, thus [...] Read more.
Low- or very-low-pressure hydrocephalus is a serious and rare phenomenon, which is becoming better known since it was first described in 1994 by Pang and Altschuler. Forced drainage at negative pressures can, in most cases, restore the ventricles to their original size, thus achieving neurological recovery. We present six new cases that suffered this syndrome from 2015 to 2020: two of them after medulloblastoma surgery; a third one as a consequence of a severe head trauma that required bifrontal craniectomy; another one after craniopharyngioma surgery; a fifth one with leptomeningeal glioneuronal tumor; and, finally, a patient carrier a shunt for normotensive hydrocephalus diagnosed ten years before. At the moment of development of this condition, four of them had mid-low-pressure cerebrospinal fluid (CSF) shunts. Four patients required cerebrospinal fluid (CSF) drainage at negative pressures oscillating from zero to −15 mmHg by external ventricular drainage until ventricular size normalized, followed by the placement of a new definitive low-pressure shunt, one of them to the right atrium. The duration of drainage in negative pressures through external ventricular drainage (EVD) ranged from 10 to 40 days with concomitant intracranial pressure monitoring at the neurointensive care unit. Approximately 200 cases of this syndrome have been described in the literature. The causes are varied and superimposable to those of high-pressure hydrocephalus. Neurological impairment is due to ventricular size and not to pressure values. Subzero drainage is still the most commonly used method, but other treatments have been described, such as neck wrapping, ventriculostomy of the third ventricle, and lumbar blood patches when associated with lumbar puncture. Its pathophysiology is not clear, although it seems to involve changes in the permeability and viscoelasticity of the brain parenchyma together with an imbalance in CSF circulation in the craniospinal subarachnoid space. Full article
(This article belongs to the Special Issue Recent Advances and Current Controversies in Hydrocephalus)
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13 pages, 2604 KiB  
Review
Transthyretin Cardiac Amyloidosis: A Cardio-Orthopedic Disease
by Federico Perfetto, Mattia Zampieri, Giulia Bandini, Roberto Fedi, Roberto Tarquini, Raffaella Santi, Luca Novelli, Marco Allinovi, Alessia Argirò and Francesco Cappelli
Biomedicines 2022, 10(12), 3226; https://doi.org/10.3390/biomedicines10123226 - 12 Dec 2022
Cited by 7 | Viewed by 3861
Abstract
Orthopaedic manifestations of wild-type transthyretin amyloidosis are frequent and characteristic, including idiopathic bilateral carpal tunnel syndrome, idiopathic lumbar canal stenosis, atraumatic rupture of the brachial biceps tendon, and, more rarely, finger disease and rotator cuff. These manifestations often coexisting in the same patient, [...] Read more.
Orthopaedic manifestations of wild-type transthyretin amyloidosis are frequent and characteristic, including idiopathic bilateral carpal tunnel syndrome, idiopathic lumbar canal stenosis, atraumatic rupture of the brachial biceps tendon, and, more rarely, finger disease and rotator cuff. These manifestations often coexisting in the same patient, frequently male and aged, steadily precede cardiac involvement inducing a rapidly progressive heart failure with preserved ejection fraction. Although transthyretin cardiac amyloidosis remains a cardiac relevant disease, these extracardiac localisation may increase diagnostic suspicion and allow for early diagnosis assuming the role of useful diagnostic red flags, especially in light of new therapeutic opportunities that can slow or stop the progression of the disease. For the cardiologist, the recognition of these extracardiac red flags is of considerable importance to reinforce an otherwise less emerging diagnostic suspicion. For orthopedists and rheumatologists, the presence in an old patient with or without clinical manifestations of cardiovascular disease, of an unexpected and inexplicable constellation of musculoskeletal symptoms, can represent a fundamental moment for an early diagnosis and treatment is improving a patient’s outcome. Full article
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