Search Results (623)

The impact of Oedema Disease produced by Shiga toxigenic Escherichia coli (STEC) in swine is increasing in some production countries due to increasing limitations on treatment with antimicrobials and zinc oxide, either because of the increased prevalence of multi-resistant strains or because of legal restrictions. The main pathological effect of Shiga toxin 2e is represented by damage to the endothelial cells of the blood vessel walls, leading to liquid extravasation and oedema formation in multiple tissues. These oedemas are generally easily identifiable in acute clinical cases. However, disease caused by Shiga toxin can occur without any externally visible oedema in the pigs, as observed in the subclinical presentation of Oedema Disease. It also causes productive losses, so it is important to identify and/or diagnose cases to set up control measures in order to optimize production and health. This article includes a comprehensive review of lesions and signs caused by Shiga toxin toxicosis in pigs, as well as other insights about the aetiology and epidemiology of STEC in pigs, and the effect of Shiga toxin recombinant toxoid vaccines in reducing these clinical and subclinical signs under field conditions. Full article

Background/Objectives: Respectful maternity care involves privacy, dignity, and informed choice within the process of delivery as stipulated by the World Health Organization (WHO). Informed consent is a cornerstone of patient-centered care, representing not just a formal document, but an ongoing ethical and clinical process through which women are offered objective, understandable information to support autonomous, informed decision-making. Methods: This narrative review critically examines the literature on informed consent in maternity care, with particular attention to both obstetric-led and midwifery-led models of care. In addition to identifying institutional, cultural, and systemic obstacles to its successful implementation, the review examines the definition and application of informed consent in perinatal settings and evaluates its effects on women’s autonomy and satisfaction with care. Results: Important conclusions emphasize that improving women’s experiences and minimizing needless interventions require active decision-making participation, a positive provider–patient relationship, and ongoing support from medical professionals. However, significant gaps persist between legal mandates and actual practice due to provider attitudes, systemic constraints, and sociocultural influences. Women’s experiences of consent can be more effectively understood through the use of instruments such as the Mothers’ Respect (MOR) Index and the Mothers’ Autonomy in Decision Making (MADM) Scale. Conclusions: To promote genuinely informed and considerate maternity care, this review emphasizes the necessity of legislative reform and improved provider education in order to close the gap between policy and practice. Full article

Yeasts possess a range of environmental adaptations that allow them to colonize soil and sand. They can circulate seasonally between different components of lake ecosystems, including beach sand, water, and the coastal phyllosphere. The accumulation of people on beaches promotes the development and transmission of yeasts, posing an increasing sanitary and epidemiological risk. The aim of this study was to determine the species and quantitative composition of potentially pathogenic and pathogenic yeasts for humans present in the sand of supervised and unsupervised beaches along the shores of lakes in the city of Olsztyn (northeastern Poland). The study material consisted of sand samples collected during two summer seasons (2019; 2020) from 12 research sites on sandy beaches of four lakes located within the administrative boundaries of Olsztyn. Standard isolation and identification methods used in diagnostic mycological laboratories were applied and are described in detail in the following sections of this study. A total of 259 yeast isolates (264, counting species in two-species isolates separately) belonging to 62 species representing 47 genera were obtained during the study. Among all the isolates, five were identified as mixed (two species from a single colony). Eight isolated species were classified into biosafety level 2 (BSL-2) and risk group 2 (RG-2). The highest average number of viable yeast cells was found in sand samples collected in July 2019 (5.56 × 10² CFU/g), August, and September 2020 (1.03 × 10³ CFU/g and 1.94 × 10³ CFU/g, respectively). The lowest concentrations were in samples collected in April, September, and October 2019, and October 2020 (1.48 × 10² CFU/g, 1.47 × 10² CFU/g, 1.40 × 10² CFU/g, and 1.40 × 10² CFU/g, respectively). The results indicate sand contamination with yeasts that may pose etiological factors for human mycoses. In light of these findings, continuous sanitary-epidemiological monitoring of beach sand and further studies on its mycological cleanliness are warranted, along with actions leading to appropriate legal regulations. Full article

Volcanic islands host exceptional geological features that illustrate complex endogenic processes and interactions with climatic and marine forces, while also being particularly vulnerable to the impacts of climate change. Despite their scientific, educational, touristic, and aesthetic values, such islands remain underrepresented within the UNESCO Global Geoparks (UGGp). This study reviews current volcanic island geoparks and evaluates territories with potential for future designation, based on documented geoheritage, geosite inventories, and geoconservation frameworks. Geoparks are categorized according to their dominant narratives—ranging from recent Quaternary volcanism to broader tectonic, sedimentary, and metamorphic histories. Through an analysis of their distribution, management strategies, and integration into territorial planning, this work highlights the challenges that insular territories face, including vulnerability to global environmental change, limited legal protection, and structural inequalities in access to international resources recognition. It concludes that volcanic island geoparks represent strategic platforms for implementing sustainable development models, especially in ecologically and socially fragile contexts. Enhancing their global representation will require targeted efforts in ecologically and socially fragile contexts. Enhancing their global representation will require targeted efforts in capacity building, funding access, and regional cooperation—particularly across the Global South. Full article

This study focuses on the position of civil law research in the Web of Science (WoS) and Scopus scientific databases. Two of the most reputable university rankings, the Shanghai Ranking of World Universities (Shanghai University Rankings) and the Times Higher Education rankings, evaluate the quality of research on the law subject matter directly based on its position in the WoS and Scopus, respectively. This study shows that there are only 13 civil law journals in WoS, while the situation is only slightly better in Scopus. That is why the civil law colleges are ranked much lower in the Shanghai rankings and still very low in the Times Higher Education rankings. This study, in particular, indicates that there are a low number of civil law journals published in languages other than English. Thereby, the most important civil law journals are excluded from the evaluation, and the rankings of civil law colleges are not accurate. The study further focuses on the number of journals included in the WoS and Scopus in a specific area of civil and commercial law. It shows that several core legal areas of civil and commercial law either are not covered at all in WoS and Scopus or are available in very few journals that publish legal research only in the English language. It further reveals that very few languages other than English are represented in WoS and Scopus in the civil law area, and some important civil law nations are not represented by a single law journal publishing in their official languages. This research aims to provide suggestions for university rankings and academic databases on how to evaluate civil law research more appropriately. Full article

Background: Suicide in older adults represents an insufficiently addressed public health problem, despite the aging population and the increase in mental disorders in this group. The COVID-19 pandemic and associated measures, such as lockdown, could have exacerbated this phenomenon. This study aimed to analyze the impact of the confinement decreed during the state of alarm in Spain on the incidence of deaths by suicide in people over 70 years of age in Extremadura. Methods: An observational and retrospective study was carried out, using data from the Institutes of Legal Medicine and Forensic Sciences, comparing the figures for 2020 with the years 2019, 2021, along with the average for the period 2015–2019. Statistical analyses included Chi-square tests and calculation of Relative Risk with 95% CI. Results: The results revealed a significant increase in deaths by suicide in the third quarter of 2020 compared to the periods compared, especially among men. Conclusions: It is concluded that confinement may have negatively influenced the mental health of older adults, which underscores the need for specific interventions and attention to regional contextual factors. Full article

Groundwater contamination by nitrates (NO₃⁻) and nitrites (NO₂⁻) is an urgent problem in rural areas of Eastern Europe, with profound public health and sustainability implications. This paper presents an integrated assessment of groundwater vulnerability and water quality in rural wells in the Ceanu Mare commune, Cluj County, Romania—a representative area of the Northern Transylvania Basin, characterized by diverse geological structures, intensive agricultural activities, and incomplete public water infrastructure. This study combines detailed hydrochemical analyses, household-level studies, and geological context to identify and quantify key factors influencing nitrate and microbial contamination in rural wells, providing a comprehensive perspective on water quality challenges in the central part of Romania. This study adopts a multidisciplinary approach, integrating detailed geotechnical investigations conducted through four strategically located boreholes. These are complemented by extensive hydrogeological and lithological characterization, as well as rigorous chemical and microbiological analyses of nearby wells. The results reveal persistently elevated concentrations of NO₃⁻ and NO₂⁻, commonly associated with inadequate livestock waste management and the proximity of manure storage areas. Microbiological contamination was also frequent. In this study, the NO₃⁻ levels in well water ranged from 39.7 to 48 mg/L, reaching up to 96% of the EU/WHO threshold (50 mg/L), while the NO₂⁻ concentrations varied from 0.50 to 0.69 mg/L, exceeding the legal limit (0.5 mg/L) in 87% of the sampled wells. Ammonium (NH₄⁺) was detected (0.25–0.34 mg/L) in all the wells, below the maximum allowed limit (0.5 mg/L) but indicative of ongoing organic pollution. All the well water samples were non-compliant for microbiological parameters, with E. coli detected in 100% of cases (5–13 CFU/100 mL). The regional clay–marl substrate offers only limited natural protection against pollutant infiltration, primarily due to lithological heterogeneity and discontinuities observed within the clay–marl layers in the study area. This research delivers a replicable model for rural groundwater assessment and addresses a critical gap in regional and European water safety studies. It also provides actionable recommendations for sustainable groundwater management, infrastructure development, and community risk reduction in line with EU water directives. Full article

Freshwater ecosystems face escalating degradation, demanding real-time, scalable, and biodiversity-aware monitoring solutions. This review proposes an integrated framework combining artificial intelligence (AI), geographic information systems (GISs), and environmental DNA (eDNA) to overcome these limitations and support next-generation river health assessment. The AI-GIS-eDNA system was applied to four representative river basins—the Mississippi, Amazon, Yangtze, and Danube—demonstrating enhanced predictive accuracy (up to 94%), spatial pollution mapping precision (85–95%), and species detection sensitivity (+18–30%) compared to conventional methods. Furthermore, the framework reduces operational costs by up to 40%, highlighting its potential for cost-effective deployment in low-resource regions. Despite its strengths, challenges persist in the areas of regulatory acceptance, data standardization, and digital infrastructure. We recommend legal recognition of AI and eDNA indicators, investment in explainable AI (XAI), and global data harmonization initiatives. The integrated AI-GIS-eDNA framework offers a scalable and policy-relevant tool for adaptive freshwater governance in the Anthropocene. Full article

The use of artificial intelligence (AI) in dermatology is skyrocketing, but a comprehensive overview integrating regulatory, ethical, validation, and clinical issues is lacking. This work aims to review current research, map applicable legal regulations, identify ethical challenges and methods of verifying AI models in dermatology, assess publication trends, compare the most popular neural network architectures and datasets, and identify good practices in creating AI-based applications for dermatological use. A systematic literature review is conducted in accordance with the PRISMA guidelines, utilising Google Scholar, PubMed, Scopus, and Web of Science and employing bibliometric analysis. Since 2016, there has been exponential growth in deep learning research in dermatology, revealing gaps in EU and US regulations and significant differences in model performance across different datasets. The decision-making process in clinical dermatology is analysed, focusing on how AI is augmenting skin imaging techniques such as dermatoscopy and histology. Further demonstration is provided regarding how AI is a valuable tool that supports dermatologists by automatically analysing skin images, enabling faster diagnosis and the more accurate identification of skin lesions. These advances enhance the precision and efficiency of dermatological care, showcasing the potential of AI to revolutionise the speed of diagnosis in modern dermatology, sparking excitement and curiosity. Then, we discuss the regulatory framework for AI in medicine, as well as the ethical issues that may arise. Additionally, this article addresses the critical challenge of ensuring the safety and trustworthiness of AI in dermatology, presenting classic examples of safety issues that can arise during its implementation. The review provides recommendations for regulatory harmonisation, the standardisation of validation metrics, and further research on data explainability and representativeness, which can accelerate the safe implementation of AI in dermatological practice. Full article

Legal requirements for minimum distances between vehicles are often not met for short periods of time, especially when changing lanes on multi-lane roads. These situations are typically non-hazardous, as human drivers anticipate surrounding traffic, allowing for shorter headways and improved traffic flow. Automated vehicles (AVs), however, are typically designed to maintain strict headway limits, potentially reducing traffic efficiency. Therefore, legal questions arise as to whether mandatory gap and headway limits for AVs may be violated during periods of non-compliance. While traffic flow simulation is a common method for analyzing AV impacts, previous studies have typically modeled AV behavior using driver models originally designed to replicate human driving. These models are not well suited for representing clearly defined, structured non-compliant maneuvers, as they cannot simulate intentional, rule-deviating strategies. This paper addresses this gap by introducing a concept for AV non-compliant behavior and implementing it as a module within a pre-existing AV driver model. Simulations were conducted on a three-lane highway with an on-ramp under varying traffic volumes and AV penetration rates. The results showed that, with an AV-penetration rate of more than 25%, road capacity at highway entrances could be increased and travel times reduced by over 20%, provided that AVs were allowed to merge with a legal gap of 0.9 s and a minimum non-compliant gap of 0.6 s lasting up to 3 s. This suggests that performance gains are achievable under adjusted legal requirements. In addition, the proposed framework can serve as a foundation for further development of AV driver models aiming at improving traffic efficiency while maintaining regulatory compliance. Full article

Global refugee flows’ increasing scale and complexity pose significant challenges to national education systems. Turkey, hosting one of the largest populations of refugees and individuals under temporary protection, faces unique pressures in ensuring equitable educational access for refugee students. Addressing these challenges requires a shift from linear, fragmented interventions toward holistic, systemic approaches. This study applies a Community-Based System Dynamics (CBSD) methodology to explore the systemic barriers affecting refugee students’ participation in education. Through structured Group Model Building workshops involving teachers, administrators, and Non-Governmental Organization (NGO) representatives, a causal loop diagram (CLD) was collaboratively developed to capture the feedback mechanisms and interdependencies sustaining educational inequalities. Five thematic subsystems emerged: language and academic integration, economic and family dynamics, psychosocial health and trauma, institutional access and legal barriers, and social cohesion and discrimination. The analysis reveals how structural constraints, social dynamics, and individual behaviors interact to perpetuate exclusion or facilitate integration. This study identifies critical feedback loops and leverage points and provides actionable insights for policymakers and practitioners seeking to design sustainable, systems-informed interventions. Our findings emphasize the importance of participatory modeling in addressing complex societal challenges and contribute to advancing systems thinking in refugee education. Full article

As major countries around the world have successively proposed the construction goal of “Beautiful National Land Space”, how to effectively integrate urban design with spatial control in specific geographical environments and use urban design to achieve efficient spatial control has become a new research trend. The process of planning the national territory is constrained by the legal framework, involving multiple planning stages and multiple stakeholders. In an ideal state, these planning stages and stakeholders should coordinate with each other, but during the actual implementation of the plan, these factors are often not coordinated enough, making it difficult for the plan to play a role. In this study, Mile City in Yunnan Province, a representative city in the unique intermontane basin area of Southwestern China, was used as a case to explore how to use urban design methods in territorial spatial planning to achieve more efficient spatial control. This study provides scientific support for establishing an indicator control system for urban design methods by combining multiple data collection methods such as text analysis, image analysis, and interview methods. The distinctive features of Mile City have been further enhanced by optimizing its spatial layout through urban design, and it has been scientifically integrated into the territorial spatial planning system. The results indicate that the successful implementation of urban design highly relies on the reform willingness of local governments, clear control frameworks, and the coordinated integration of regional ecological resources and landscape features. This study proposed a set of urban design control methods suitable for intermontane basin-type cities and formed a comprehensive control framework including city, town, and landscape. In addition, it will provide methodological support and references for improving the scientific management of “Beautiful Land” in the special geographical environment of Southwest China. Full article

3D (three-dimensional) property volume is an important data carrier for 3D land administration by using 3D cadastral technology, which can be used to express the legal space (property rights) scope matching with physical entities such as buildings and land. A 3D property volume is represented by a dense set of 3D coordinate points arranged in a predefined order and is displayed alongside the parcel map for reference and utilization by readers. To store a 3D property volume in the database, it is essential to record the connectivity relationships among the original 3D coordinate points, the associations between points and lines for representing boundary lines, and the relationships between lines for defining surfaces. Only by preserving the data structure that represents the relationships among points, lines, and surfaces can the 3D property volume in a parcel map be fully reconstructed. This approach inevitably results in the database storage volume significantly exceeding the original size of the point set, thereby causing storage redundancy. Consequently, this paper introduces a reversible 3D property volume compression coding method (called 3DPV-CC) to address this issue. By analyzing the distribution characteristics of the coordinate points of the 3D property volume, a specific rule for sorting the coordinate points is designed, enabling the database to have the ability of data storage and recovery by merely storing a reordered point set. The experimental results show that the 3DPV-CC method has excellent support capabilities for 3D property volumes of the vertical and slopped types, and can compress and restore the coordinate point set of the 3D property volume for drawing 3D parcel maps. The compression capacity of our method in the test is between 23.66% and 38.42%, higher than the general data compression methods (ZIP/7Z/RAR: 8.37–10.32%). By means of this method, land or real estate administrators from government departments can store 3D property volume data at a lower cost. This is conducive to enhancing the informatization level of land management. Full article

The combustion of fossil fuels is a major source of greenhouse gas emissions, drives climate change, and has intensified the search for cleaner energy alternatives such as biomass. Biomass derived from renewable organic materials, is considered a sustainable and carbon-neutral energy source. While biomass represents a renewable and clean energy source, its combustion, especially in pellet form, can produce various pollutants such as CO₂, SO₂, NO₂, CO, and PM. This study focuses on analyzing the combustion of six different pellet brands and the emissions they produce. A dedicated experimental procedure was designed and implemented to evaluate the combustion performance. The temperature shows a gradual increase in ambient temperature around 2.5 °C across all tests, with a similar behavior, the temperature of flue gas shows a similar behavior between tests with temperatures peaking around 300 °C and 340 °C. In the tests conducted, all pellets complied with the legal emission limits defined by legislation. The efficiency calculated using the direct method was lower by around 55%, primarily due to the use of an older boiler (manufactured in 2004) and short duration of the test. The indirect method shows better efficiency, around 70%, influenced by lower moisture content of the pellets. The results indicate that B pellets had a superior performance compared to the others evaluated. Full article

Blockchain technology is being increasingly deployed to store and process transactions and information in the global financial sector. Blockchain underpins cryptocurrencies such as Bitcoin and facilitates decentralized finance (DeFi), representing a paradigm shift in the global financial landscape, offering alternative solutions to traditional banking, and fostering financial inclusion. In developing economies such as Morocco, where a significant portion of the population remains unbanked, these digital financial innovations present both opportunities and challenges. This study examines the potential role of cryptocurrencies and DeFi in enhancing financial inclusion in Morocco, where cryptocurrencies have been banned since 2017. However, the public continues to use cryptocurrencies, circumventing restrictions, and the Moroccan Central Bank is now preparing to introduce new regulations to legalize their use within the country. In this context, this article analyses the potential of cryptocurrencies to mitigate barriers such as high transaction costs, restricted access to financial services in rural areas, and limited financial literacy in the country. The study pursues a mixed-methods approach, which combines a quantitative survey with qualitative expert interviews and adapts the Unified Theory of Acceptance and Use of Technology (UTAUT) model to the Moroccan context. The findings reveal that while cryptocurrencies offer cost-efficient financial transactions and improved accessibility, their adoption may be constrained by regulatory uncertainty, security risks, and technological limitations. The novelty of the article thus lies in its focus on the key mechanisms that influence the adoption of cryptocurrencies and their potential impact in a specific national context. In so doing, the study highlights the need for a structured regulatory framework, investment in digital infrastructure, and targeted financial literacy initiatives to optimize the potential role of cryptocurrencies in progressing financial inclusion in Morocco. This underscores the need for integrated models and guidelines for policymakers, financial institutions, and technology providers to ensure the responsible introduction of cryptocurrencies in developing world environments. Full article