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44 pages, 29355 KB  
Article
Bayesian-Inspired Dynamic-Lag Causal Graphs and Role-Aware Transformers for Landslide Displacement Forecasting
by Fan Zhang, Yuanfa Ji, Xiaoming Liu, Siyuan Liu, Zhang Lu, Xiyan Sun, Shuai Ren and Xizi Jia
Entropy 2026, 28(1), 7; https://doi.org/10.3390/e28010007 (registering DOI) - 20 Dec 2025
Viewed by 30
Abstract
Increasingly frequent intense rainfall is increasing landslide occurrence and risk. In southern China in particular, steep slopes and thin residual soils produce frequent landslide events with pronounced spatial heterogeneity. Therefore, displacement prediction methods that function across sites and deformation regimes in similar settings [...] Read more.
Increasingly frequent intense rainfall is increasing landslide occurrence and risk. In southern China in particular, steep slopes and thin residual soils produce frequent landslide events with pronounced spatial heterogeneity. Therefore, displacement prediction methods that function across sites and deformation regimes in similar settings are essential for early warning. Most existing approaches adopt a multistage pipeline that decomposes, predicts, and recombines, often leading to complex architectures with weak cross-domain transfer and limited adaptability. To address these limitations, we present CRAFormer, a causal role-aware Transformer guided by a dynamic-lag Bayesian network-style causal graph learned from historical observations. In our system, the discovered directed acyclic graph (DAG) partitions drivers into five causal roles and induces role-specific, non-anticipative masks for lightweight branch encoders, while a context-aware Top-2 gate sparsely fuses the branch outputs, yielding sample-wise attributions. To safely exploit exogenous rainfall forecasts, next-day rainfall is entered exclusively through an ICS tail with a leakage-free block mask, a non-negative readout, and a rainfall monotonicity regularizer. In this study, we curate two long-term GNSS datasets from Guangxi (LaMenTun and BaYiTun) that capture slow creep and step-like motions during extreme rainfall. Under identical inputs and a unified protocol, CRAFormer reduces the MAE and RMSE by 59–79% across stations relative to the strongest baseline, and it lowers magnitude errors near turning points and step events, demonstrating robust performance for two contrasting landslides within a shared regional setting. Ablations confirm the contributions of the DBN-style causal masks, the leakage-free ICS tail, and the monotonicity prior. These results highlight a practical path from causal discovery to forecast-compatible neural predictors for rainfall-induced landslides. Full article
(This article belongs to the Special Issue Bayesian Networks and Causal Discovery)
17 pages, 3453 KB  
Article
Capturing Spatiotemporal Hydraulic Connectivity for Groundwater Level Prediction in Over-Exploited Aquifers: A Multi-Source Fusion Graph Learning Approach (MF-STGCN)
by Rong Liu and Ziyu Guan
Mathematics 2025, 13(24), 3978; https://doi.org/10.3390/math13243978 - 13 Dec 2025
Viewed by 126
Abstract
Accurate prediction of shallow groundwater levels is crucial for water resource management in over-exploited regions like the North China Plain, where intensive pumping has created non-steady flow fields with strong spatial hydraulic interactions. Traditional approaches—whether physical models constrained by parameter equifinality or machine [...] Read more.
Accurate prediction of shallow groundwater levels is crucial for water resource management in over-exploited regions like the North China Plain, where intensive pumping has created non-steady flow fields with strong spatial hydraulic interactions. Traditional approaches—whether physical models constrained by parameter equifinality or machine learning methods assuming spatial independence—fail to explicitly characterize aquifer hydraulic connectivity and effectively integrate multi-source monitoring data. This study proposes a Multi-source Fusion Spatiotemporal Graph Convolutional Network (MF-STGCN) that represents the monitoring well network as a hydraulic connectivity graph, employing graph convolutions to capture spatial water level propagation patterns while integrating temporal dynamics through LSTM modules. An adaptive fusion mechanism quantifies contributions of natural drivers (precipitation, evaporation) and anthropogenic extraction to water level responses. Validation using 518 monitoring stations (2018–2022) demonstrates that MF-STGCN reduces RMSE compared to traditional time series models, with improvement primarily attributed to explicit modeling of spatial hydraulic dependencies. Interpretability analysis identifies Hebi and Shijiazhuang as severe over-exploitation zones and reveals significant response lag effects in the Handan-Xingtai corridor. This study demonstrates that spatial propagation patterns, rather than single-point temporal features, are key to improving prediction accuracy in over-exploited aquifers, providing a new data-driven paradigm for regional groundwater dynamics assessment and targeted management strategies. Full article
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22 pages, 926 KB  
Article
Structural Model of Key Determinants of Customer Loyalty in Organic Dining Restaurants Within Green Hotels
by Yingwei Pan, Chaiyawit Muangmee, Nusanee Meekaewkunchorn and Tatchapong Sattabut
Tour. Hosp. 2025, 6(5), 271; https://doi.org/10.3390/tourhosp6050271 - 9 Dec 2025
Viewed by 372
Abstract
This study moves beyond the static view prevalent in hospitality loyalty research by developing and longitudinally testing a process-oriented model of loyalty formation. Recognizing that loyalty is a dynamic outcome, we employ a three-wave panel design with a three-month lag, surveying 562 customers [...] Read more.
This study moves beyond the static view prevalent in hospitality loyalty research by developing and longitudinally testing a process-oriented model of loyalty formation. Recognizing that loyalty is a dynamic outcome, we employ a three-wave panel design with a three-month lag, surveying 562 customers of organic restaurants within green-certified hotels. Data are analyzed using a Cross-Lagged Panel Model (CLPM) to meticulously map the temporal interplay among key antecedents, controlling for autoregressive effects and covariates. The findings provide robust evidence for a specific cognitive-to-affective sequence: perceptions of food quality at one time point shape subsequent judgments of perceived value, which in turn drive customer satisfaction, ultimately fostering loyalty in a succeeding period. Crucially, the CLPM also reveals that food quality and price fairness exert significant, direct time-lagged effects on loyalty, suggesting the presence of dual psychological pathways. By establishing temporal precedence and mapping sequential mediation, this study offers a more causally robust and managerially actionable understanding of how customer loyalty evolves. Full article
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16 pages, 881 KB  
Article
Stress and Internalizing Problems in Adolescents: A Dynamic Longitudinal Analysis
by Filipa Ćavar Mišković, Maja Ribar, Daniela Šupe Domić, Petra Dumanić and Goran Milas
J. Pers. Med. 2025, 15(12), 612; https://doi.org/10.3390/jpm15120612 - 8 Dec 2025
Viewed by 398
Abstract
Background/Objectives: Internalizing problems commonly increase during adolescence, yet the precise nature of their reciprocal relationship with stress remains unclear. The present study aimed to clarify the directionality of this association by disentangling stable dispositional influences from dynamic, within-person processes. Specifically, we examined whether [...] Read more.
Background/Objectives: Internalizing problems commonly increase during adolescence, yet the precise nature of their reciprocal relationship with stress remains unclear. The present study aimed to clarify the directionality of this association by disentangling stable dispositional influences from dynamic, within-person processes. Specifically, we examined whether stress and internalizing symptoms exhibit bidirectional effects over time or are primarily shaped by enduring individual differences. Methods: A large, representative sample of 1618 secondary school students (671 males, 947 females; M = 16.3 years) completed measures of subjective stress, emotional problems, and peer problems across three time points spaced six months apart. Data were analyzed using the Random Intercept Cross-Lagged Panel Model (RI-CLPM), which separates stable between-person variance from within-person fluctuations. Model fit was assessed using established criteria (CFI, TLI, RMSEA). Results: Subjective stress and emotional problems were strongly associated, whereas the relationship between stress and peer problems was weaker. In both domains, associations were largely explained by stable, trait-like individual differences. All cross-lagged effects at the within-person level were non-significant, indicating no dynamic, time-ordered influence between constructs. These findings provide no empirical support for the stress sensitization or stress generation hypotheses but are consistent with diathesis–stress models emphasizing enduring dispositional vulnerability. Conclusions: The results suggest that the link between stress and internalizing symptoms during adolescence primarily reflects stable personality-based factors, such as neuroticism or emotional instability, rather than reciprocal causal processes. Preventive interventions should target emotional regulation and resilience to mitigate the impact of dispositional vulnerabilities on adolescent mental health. Full article
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18 pages, 1117 KB  
Article
An Enhanced, Lightweight Large Language Model-Driven Time Series Forecasting Approach for Air Conditioning System Cooling Load Forecasting
by Cong Zhu, Yongkuan Yang, Haiping Chen and Miao Zeng
Mathematics 2025, 13(23), 3887; https://doi.org/10.3390/math13233887 - 4 Dec 2025
Viewed by 278
Abstract
Accurate cooling load forecasting in high-efficiency chiller plants with ice storage systems is essential for intelligent control, energy conservation, and maintaining indoor comfort. However, conventional forecasting methods often struggle to model the complex nonlinear dependencies among influencing variables, limiting their predictive performance. To [...] Read more.
Accurate cooling load forecasting in high-efficiency chiller plants with ice storage systems is essential for intelligent control, energy conservation, and maintaining indoor comfort. However, conventional forecasting methods often struggle to model the complex nonlinear dependencies among influencing variables, limiting their predictive performance. To address this, this paper introduces Time-LLM, a novel time series forecasting framework that leverages a frozen large language model (LLM) to improve the accuracy and generalization of cooling load forecasting. Time-LLM extracts features from historical data, reformulates them as natural language prompts, and uses the LLM for temporal sequence modeling; a linear projection layer then maps the LLM output to final predictions. To enable lightweight deployment and improve temporal feature prompting, we propose ETime-LLM, an enhanced variant of Time-LLM. ETime-LLM significantly reduces deployment costs and mitigates the original model’s response lag during trend transitions by focusing on possible turning points. Extensive experiments demonstrate that ETime-LLM consistently outperforms or matches state-of-the-art baselines across short-term, long-term, and few-shot forecasting tasks. Specifically, in the commonly used 24 h forecasting horizon, compared with the original model, ETime-LLM achieves an approximately 17.3% reduction in MAE and a 19.3% reduction in RMSE. It achieves high-quality predictions without relying on costly external data, offering a robust and scalable solution for green and energy-efficient HVAC system management. Full article
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28 pages, 3050 KB  
Review
Safety Engineering for Humanoid Robots in Everyday Life—Scoping Review
by Dávid Kóczi and József Sárosi
Electronics 2025, 14(23), 4734; https://doi.org/10.3390/electronics14234734 - 1 Dec 2025
Viewed by 976
Abstract
As humanoid robots move from controlled industrial environments into everyday human life, their safe integration is essential for societal acceptance and effective human–robot interaction (HRI). This scoping review examines engineering safety frameworks for humanoid robots across four core domains: (1) physical safety in [...] Read more.
As humanoid robots move from controlled industrial environments into everyday human life, their safe integration is essential for societal acceptance and effective human–robot interaction (HRI). This scoping review examines engineering safety frameworks for humanoid robots across four core domains: (1) physical safety in HRI, (2) cybersecurity and software robustness, (3) safety standards and regulatory frameworks, and (4) ethical and societal implications. In the area of physical safety, recent research trends emphasize proactive, multimodal perception-based collision avoidance, the use of compliance mechanisms, and fault-tolerant control to handle hardware failures and falls. In cybersecurity and software robustness, studies increasingly address the full threat landscape, secure real-time communication, and reliability of artificial intelligence (AI)-based control. The analysis of standards and regulations reveals a lag between technological advances and the adaptation of key safety standards in current research. Ethical and societal studies show that safety is also shaped by user trust, perceived safety, and data protection. Within the corpus of 121 peer-reviewed studies published between 2021 and 2025 and included in this review, most work concentrates on physical safety, while cybersecurity, standardization, and socio-ethical aspects are addressed less frequently. These gaps point to the need for more integrated, cross-domain approaches to safety engineering for humanoid robots. Full article
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16 pages, 1719 KB  
Article
Gait Generation and Motion Implementation of Humanoid Robots Based on Hierarchical Whole-Body Control
by Helin Wang and Wenxuan Huang
Electronics 2025, 14(23), 4714; https://doi.org/10.3390/electronics14234714 - 29 Nov 2025
Viewed by 520
Abstract
Attempting to make machines mimic human walking, grasping, balancing, and other behaviors is a deep exploration of cognitive science and biological principles. Due to the existing prediction lag problem, an error compensation mechanism that integrates historical motion data is proposed. By constructing a [...] Read more.
Attempting to make machines mimic human walking, grasping, balancing, and other behaviors is a deep exploration of cognitive science and biological principles. Due to the existing prediction lag problem, an error compensation mechanism that integrates historical motion data is proposed. By constructing a humanoid autonomous walking control system, this paper aims to use a three-dimensional linear inverted pendulum model to plan the general framework of motion. Firstly, the landing point coordinates of the single foot support period are preset through gait cycle parameters. In addition, it is substituted into dynamic equation to solve the centroid (COM) trajectory curve that conforms to physical constraints. A hierarchical whole-body control architecture is designed, with a task priority based on quadratic programming solver used at the bottom to decompose high-level motion instructions into joint space control variables and fuse sensor data. Furthermore, the numerical iterative algorithm is used to solve the sequence of driving angles for each joint, forming the control input parameters for driving the robot’s motion. This algorithm solves the limitations of traditional inverted pendulum models on vertical motion constraints by optimizing the centroid motion trajectory online. At the same time, it introduces a contact phase sequence prediction mechanism to ensure a smooth transition of the foot trajectory during the switching process. Simulation results demonstrate that the proposed framework improves disturbance rejection capability by over 30% compared to traditional ZMP tracking and achieves a real-time control loop frequency of 1 kHz, confirming its enhanced robustness and computational efficiency. Full article
(This article belongs to the Special Issue Advances in Intelligent Computing and Systems Design)
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14 pages, 2862 KB  
Article
Prestrike Characteristics of Double-Break Vacuum Circuit Breakers in Making Power Frequency Voltage
by Siyi Wei, Xiaofei Yao, Yuqian Niu, Zongyao Ge, Haoen Sun, Minju Xu and Feiyue Ma
Electronics 2025, 14(23), 4667; https://doi.org/10.3390/electronics14234667 - 27 Nov 2025
Viewed by 226
Abstract
Vacuum circuit breakers (VCBs) have been extensively employed in switching shunt capacitor banks. However, research on the prestrike characteristics of double-break VCBs in making power frequency voltage remains limited. This study aims to investigate the influence of different closing time differences on the [...] Read more.
Vacuum circuit breakers (VCBs) have been extensively employed in switching shunt capacitor banks. However, research on the prestrike characteristics of double-break VCBs in making power frequency voltage remains limited. This study aims to investigate the influence of different closing time differences on the prestrike characteristics of double-break VCBs in making power frequency voltage, and to compare these influences with those of single-break VCBs. Experiments were conducted using vacuum interrupters rated at 24 kV, with contacts made of CuCr40 alloy doped with 1 wt% graphene. Taking the closing time of the high-voltage break as the time zero point, three closing time differences (0 ms, 0.727 ms, and −0.347 ms) were set, and experiments were carried out at six closing phase angles (from 0° to 150° in 30° increments) for each condition. The experimental results demonstrate that when the closing of the high-voltage break lags behind that of the low-voltage break by 0.347 ms, the double-break VCB exhibits optimal prestrike performance, where prestrike is almost entirely suppressed except at the 90° phase angle. Furthermore, the prestrike performance during the closing of the double-break VCB is significantly superior to that of the single-break VCB, characterized by a steeper RDDS curve. These findings provide a theoretical basis for the design of control-switching double-break VCBs. Full article
(This article belongs to the Special Issue Modern Design and Application of High-Voltage Circuit Breakers)
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21 pages, 9585 KB  
Article
Mapping Rice Cropping Systems in Data-Scarce Regions Using NDVI Time-Series and Dynamic Time Warping Clustering: A Case Study of Maliana, Timor-Leste
by Pedro Junior Fernandes and Masahiko Nagai
Appl. Sci. 2025, 15(23), 12544; https://doi.org/10.3390/app152312544 - 26 Nov 2025
Viewed by 1494
Abstract
Mapping of rice-cropping regimes is crucial for effective irrigation planning and yield monitoring, particularly in data-scarce regions. We analyzed 48 months of 3 m PlanetScope NDVI data, aggregated to a 25 m hexagonal grid, and used Dynamic Time Warping Clustering to segment phenological [...] Read more.
Mapping of rice-cropping regimes is crucial for effective irrigation planning and yield monitoring, particularly in data-scarce regions. We analyzed 48 months of 3 m PlanetScope NDVI data, aggregated to a 25 m hexagonal grid, and used Dynamic Time Warping Clustering to segment phenological patterns. Internal validation consistently identified two main clusters, indicating two dominant seasonality modes. Cluster 1 exhibited a higher mean NDVI, fewer low-canopy months, more vigorous growth periods, more peaks, and greater annual cycling, which suggests irrigated double cropping. Cluster 2 exhibited prolonged low NDVI values and a greater amplitude, consistent with single-rainfed systems. The rain–NDVI analysis supported these findings: Cluster 1 responded modestly to rainfall, whereas Cluster 2 exhibited a stronger and delayed response. Independent spatial checks confirmed these classifications. Off-season greenness, measured as NDVI above 0.50 from July to November, was concentrated near main and secondary canals and decreased with distance from intake points. This workflow combines DTW clustering with rainfall lag and off-season greenness analysis, effectively distinguishing between irrigated and rain-fed regimes using satellite time series. These findings are considered indicative rather than definitive, providing an assessment of cropping systems in Timor-Leste and demonstrating that DTW-based NDVI clustering offers a scalable approach in data-scarce regions. Full article
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22 pages, 6047 KB  
Article
Temporal and Spatial Dynamics of Groundwater Drought Based on GRACE Satellite and Its Relationship with Agricultural Drought
by Weiran Luo, Fei Wang, Mengting Du, Jianzhong Guo, Ziwei Li, Ning Li, Rong Li, Ruyi Men, Hexin Lai, Qian Xu, Kai Feng, Yanbin Li, Shengzhi Huang and Qingqing Tian
Agriculture 2025, 15(23), 2431; https://doi.org/10.3390/agriculture15232431 - 25 Nov 2025
Viewed by 323
Abstract
Terrestrial water storage includes soil water storage, groundwater storage, surface water storage, snow water equivalent, plant canopy water storage, biological water storage, etc., which can comprehensively reflect the total change in water volume during processes such as precipitation, evapotranspiration, runoff, and human water [...] Read more.
Terrestrial water storage includes soil water storage, groundwater storage, surface water storage, snow water equivalent, plant canopy water storage, biological water storage, etc., which can comprehensively reflect the total change in water volume during processes such as precipitation, evapotranspiration, runoff, and human water use in the basin hydrological cycle. The Gravity Recovery and Climate Experiment (GRACE) satellite provides a powerful tool and a new approach for observing changes in terrestrial water storage and groundwater storage. The North China Plain (NCP) is a major agricultural region in the northern arid area of China, and long-term overexploitation of groundwater has led to increasingly prominent ecological vulnerability issues. This study uses GRACE and Global Land Data Assimilation System (GLDAS) hydrological model data to assess the spatiotemporal patterns of groundwater drought in the NCP and its various sub-regions from 2003 to 2022, identify the locations, occurrence probabilities, and confidence intervals of seasonal and trend mutation points, quantify the complex interactive effects of multiple climate factors on groundwater drought, and reveal the propagation time from groundwater drought to agricultural drought. The results show that: (1) from 2003 to 2022, the linear tendency rate of groundwater drought index (GDI) was −0.035 per 10 years, indicating that groundwater drought showed a gradually worsening trend during the study period; (2) on an annual scale, the most severe groundwater drought occurred in 2021 (GDI = −1.59). In that year, the monthly average GDI in the NCP ranged from −0.58 to −2.78, and the groundwater drought was most severe in July (GDI = −2.02); (3) based on partial wavelet coherence, the best univariate, bivariate for groundwater drought were soil moisture (PASC = 19.13%); and (4) in Beijing, Tianjin and Hebei, the propagation time was mainly concentrated in 1–5 months, with average lag times of 2.87, 3.20, and 2.92 months, respectively. This study can not only reduce and mitigate the harm of groundwater drought to agricultural production, social life, and ecosystems by monitoring changes in groundwater storage, but also provide a reference for the quantitative identification of the dominant factors of groundwater drought. Full article
(This article belongs to the Section Ecosystem, Environment and Climate Change in Agriculture)
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35 pages, 7205 KB  
Article
Spatiotemporal Evolution and Drivers of the Carbon Footprint and Embodied Carbon Transfer in the Advanced Manufacturing Industry: Case Study of the Western Region in China
by Yan Zou, Yinlong Li and Zhijie Han
Sustainability 2025, 17(22), 10272; https://doi.org/10.3390/su172210272 - 17 Nov 2025
Viewed by 320
Abstract
Motivated by the policy urgency of China’s dual-carbon goals and the practical obstacle that official input–output (IO) and MRIO tables are sparse and non-consecutive, this study investigates how to generate credible, mechanism-aware provincial–sector forecasts of carbon footprints and embodied transfers for Western China—a [...] Read more.
Motivated by the policy urgency of China’s dual-carbon goals and the practical obstacle that official input–output (IO) and MRIO tables are sparse and non-consecutive, this study investigates how to generate credible, mechanism-aware provincial–sector forecasts of carbon footprints and embodied transfers for Western China—a region with pronounced structural heterogeneity. We develop a regionalized forecasting pipeline that fuses balance-constrained MRIO completion (RAS–CE) with a Whale-optimized Grey Neural Network (WOA–GNN), bridging the data gap (2007–2017 reconstruction) and delivering 2018–2030 projections at province–sector resolution. The novelty lies in integrating RAS–CE with a meta-heuristic grey learner and layering explainable network analytics—Grey Relational Analysis (GRA) for factor ranking, complex-network measures with QAP regressions for driver identification, and SHAP for post hoc interpretation—so forecasts are not only accurate but also actionable. Empirically, (i) energy mix/intensity and output scale are the dominant amplifiers of footprints, while technology upgrading (process efficiency, electrification) is the most robust mitigator; (ii) a structural sectoral hierarchy persists—S2 (non-metallic minerals) remains clinker/heat-intensive, S3 (general/special equipment) operates as a mid-chain hub, and S6/S7 (electrical machinery/instruments) maintain lower, more controllable intensities as the grid decarbonizes; (iii) by 2030, the embodied carbon network becomes denser and more centralized, with Sichuan–Chongqing–Guizhou–Guangxi forming high-betweenness corridors; and (iv) QAP/SHAP converge on geographic contiguity (D) and economic differentials (E) as the strongest positive drivers (openness Z and technology gaps T secondary; energy-mix differentials F weakly dampening). Policy-wise, the framework points to green-power contracting and trading for hubs, deep retrofits in S2/S3 (low-clinker binders, waste-heat recovery, efficient drives, targeted CCUS), technology diffusion to lagging provinces, and corridor-level governance—demonstrating why the RAS–CE + WOA–GNN coupling is both necessary and impactful for data-constrained regional carbon planning. Full article
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24 pages, 1442 KB  
Article
Enhancing Student Motivation and Competencies via the WWH Teaching Method: A Case Study on the NoSQL Database Course
by Bin Yu, Yihong Liu, Yuhui Fan, Shaohua Liu, Xiaoyan Li and Ruoyu Li
Electronics 2025, 14(22), 4453; https://doi.org/10.3390/electronics14224453 - 14 Nov 2025
Viewed by 289
Abstract
NoSQL databases are vital for modern big data applications, yet traditional teaching methods struggle with lagging content, insufficient practice, and low student engagement. To address these issues, this paper proposes the WWH-integrated teaching method “Why learn, What learn, How learn” for a NoSQL [...] Read more.
NoSQL databases are vital for modern big data applications, yet traditional teaching methods struggle with lagging content, insufficient practice, and low student engagement. To address these issues, this paper proposes the WWH-integrated teaching method “Why learn, What learn, How learn” for a NoSQL database course. WWH combines three core approaches: the general–special method, which structures knowledge from foundational concepts to specialized technologies; the comparative method, which contextualizes NoSQL value via real-scenario analysis; and the theory–practice combination method, which links concepts to hands-on tasks, supplemented by the problem-guidance and key-highlighting strategies. A quasi-experiment with two cohorts (80 students each; 2023 cohort as control, 2024 as experimental) validated WWH. Quantitative results showed significant improvements: theoretical exam scores rose by 9.2 points (t(158) = 9.21, p < 0.001) and experimental scores by 10.3 points (t(158) = 7.92, p < 0.001), and classroom discussion rates increased from 45.2% to 82.7% (χ2(1) = 28.90, p < 0.001). Qualitative analysis of student essays and project reports further confirmed deeper conceptual understanding, stronger tradeoff awareness, and enhanced knowledge integration in the experimental cohort. This study provides an evidence-based, student-centered framework for modernizing NoSQL instruction, better preparing students for industry data management needs. Full article
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20 pages, 2110 KB  
Article
Gene Regulatory Network Inference Relating to Glycolysis in Escherichia coli with Causal Discovery Method Based on Machine Learning
by Akihito Nakanishi, Natsumi Omino, Ren Owa, Hayato Kinoshita and Hiroaki Fukunishi
Bacteria 2025, 4(4), 60; https://doi.org/10.3390/bacteria4040060 - 13 Nov 2025
Viewed by 423
Abstract
Escherichia coli LS5218 is an attractive host for producing polyhydroxybutyrate. The strain, however, strongly requires heterologous gene expressions like phaC for efficient production. For enhancing the production, the whole gene expressions relating to end product-producing flow should be optimized so that not only [...] Read more.
Escherichia coli LS5218 is an attractive host for producing polyhydroxybutyrate. The strain, however, strongly requires heterologous gene expressions like phaC for efficient production. For enhancing the production, the whole gene expressions relating to end product-producing flow should be optimized so that not only heterologous induced-genes but also other relating genes are comprehensively analyzed on the transcription levels, resulting in normally time-consuming mutant-creation. Additionally, the explanation for each transcriptional relationship is likely to follow the relationships on known metabolic pathway map to limit the consideration. This study aimed to infer gene regulatory networks within glycolysis, a central metabolic pathway in LS5218, using machine learning-based causal discovery methods. To construct a directed acyclic graph representing the gene regulatory network, we employed the NOTEARS algorithm (Non-combinatorial Optimization via Trace Exponential and Augmented lagRangian for Structure learning). Using transcription data of 264 time-resolved sampling points, we inferred the gene regulatory network and identified several distal regulatory relationships. Notably, gapA, a key enzyme controlling the transition between the preparatory and rewarding phases in glycolysis, was found to influence pgi, the enzyme at the pathway’s entry point. These findings suggest that inferring such nonlocal regulatory interactions can provide valuable insights for guiding genetic engineering strategies. Full article
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45 pages, 10023 KB  
Article
Path Planning for Autonomous Vehicle Control in Analogy to Supersonic Compressible Fluid Flow—An Obstacle Avoidance Scenario in Vehicular Traffic Flow
by Kasra Amini and Sina Milani
Future Transp. 2025, 5(4), 173; https://doi.org/10.3390/futuretransp5040173 - 10 Nov 2025
Cited by 1 | Viewed by 517
Abstract
There have been many attempts to model the flow of vehicular traffic in analogy to the flow of fluids. Given the evident change in distance between vehicles driving in platoons, the compressibility of traffic flow is inferred and, considering the reaction time-scales of [...] Read more.
There have been many attempts to model the flow of vehicular traffic in analogy to the flow of fluids. Given the evident change in distance between vehicles driving in platoons, the compressibility of traffic flow is inferred and, considering the reaction time-scales of the driver (human or autonomous), it is argued that this compressibility is increased as relative velocities increase—giving the lag in imposed redirection by the driver and the controller units a higher relative importance. Therefore, a supersonic compressible flow field has been opted for as the most analogous base flow. On this point, added to by the overall extreme similarities of the two above-mentioned flows, the non-dimensional group of the traffic Mach number MT has been defined in the present research, providing the possibility of calculating a suggested flow field and its corresponding shockwave systems, for any given obstacle ahead of the traffic flow. This suggested flow field is then taken as the basis to obtain trajectories designed for avoiding collision with the obstacle, and in compliance with the physics of the underlying analogous fluid flow phenomena, namely the internal supersonic compressible flow around a double wedge. It should be noted that herein we do not model the traffic flow but propose these trajectories for more optimal collision avoidance, and therefore the above-mentioned similarities (explained in detail in the manuscript) suffice, without the need to rely on full analogies between the two flows. The manuscript further analyzes the applicability of the proposed analogy in the path-planning process for an autonomous passenger vehicle, through dynamics and control of a full-planar vehicle model with an autonomous path-tracking controller. Simulations are performed using realistic vehicle parameters and the results show that the fluid flow analogy is compatible with the vehicle dynamics, as it is able to follow the target path generated by fluid flow calculations with minor deviations. Simulation results demonstrate that the proposed method produces smooth and dynamically consistent trajectories that remain stable under varying traffic scenarios. The controller achieves accurate path tracking and rapid convergence, confirming the feasibility of the fluid-flow analogy for real-time vehicle control. Full article
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51 pages, 56694 KB  
Article
Spatial Flows of Information Entropy as Indicators of Climate Variability and Extremes
by Bernard Twaróg
Entropy 2025, 27(11), 1132; https://doi.org/10.3390/e27111132 - 31 Oct 2025
Viewed by 718
Abstract
The objective of this study is to analyze spatial entropy flows that reveal the directional dynamics of climate change—patterns that remain obscured in traditional statistical analyses. This approach enables the identification of pathways for “climate information transport”, highlights associations with atmospheric circulation types, [...] Read more.
The objective of this study is to analyze spatial entropy flows that reveal the directional dynamics of climate change—patterns that remain obscured in traditional statistical analyses. This approach enables the identification of pathways for “climate information transport”, highlights associations with atmospheric circulation types, and allows for the localization of both sources and “informational voids”—regions where entropy is dissipated. The analytical framework is grounded in a quantitative assessment of long-term climate variability across Europe over the period 1901–2010, utilizing Shannon entropy as a measure of atmospheric system uncertainty and variability. The underlying assumption is that the variability of temperature and precipitation reflects the inherently dynamic character of climate as a nonlinear system prone to fluctuations. The study focuses on calculating entropy estimated within a 70-year moving window for each calendar month, using bivariate distributions of temperature and precipitation modeled with copula functions. Marginal distributions were selected based on the Akaike Information Criterion (AIC). To improve the accuracy of the estimation, a block bootstrap resampling technique was applied, along with numerical integration to compute the Shannon entropy values at each of the 4165 grid points with a spatial resolution of 0.5° × 0.5°. The results indicate that entropy and its derivative are complementary indicators of atmospheric system instability—entropy proving effective in long-term diagnostics, while its derivative provides insight into the short-term forecasting of abrupt changes. A lag analysis and Spearman rank correlation between entropy values and their potential supported the investigation of how circulation variability influences the occurrence of extreme precipitation events. Particularly noteworthy is the temporal derivative of entropy, which revealed strong nonlinear relationships between local dynamic conditions and climatic extremes. A spatial analysis of the information entropy field was also conducted, revealing distinct structures with varying degrees of climatic complexity on a continental scale. This field appears to be clearly structured, reflecting not only the directional patterns of change but also the potential sources of meteorological fluctuations. A field-theory-based spatial classification allows for the identification of transitional regions—areas with heightened susceptibility to shifts in local dynamics—as well as entropy source and sink regions. The study is embedded within the Fokker–Planck formalism, wherein the change in the stochastic distribution characterizes the rate of entropy production. In this context, regions of positive divergence are interpreted as active generators of variability, while sink regions function as stabilizing zones that dampen fluctuations. Full article
(This article belongs to the Special Issue 25 Years of Sample Entropy)
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