Search Results (11)

Accurately assessing the accessibility of fire services is critical for enhancing urban safety and the resilience of the built environment. However, existing studies often lack a systematic analysis of spatiotemporal dynamics across an entire municipality. To address this gap, this study develops a citywide dynamic assessment framework for Shanghai, integrating GIS with real-time traffic data across 240 consecutive intervals to assess the service accessibility of 195 fire stations in relation to 7973 key units of fire safety. The principal findings are threefold. First, the results reveal significant urban–suburban heterogeneity in emergency response times. Notably, the proximity advantage of fire stations in central urban areas is offset by traffic congestion, and the marginal benefit of traffic speed improvement exhibits a sharp decline once the average speed exceeds a critical threshold of 13.7–21.0 km/h. Second, the accessibility ratio demonstrates a clear temporal pattern, being highest on holidays and lowest during weekday peak hours, and follows a nonlinear spatial decline from the urban centre to the periphery. This pattern is influenced more critically by the matching of supply and demand than by fire station density alone. Third, the analysis identifies dynamic vulnerability hotspots, which display a ‘bimodal (M-shaped)’ pattern on weekdays and a ‘unimodal (A-shaped)’ pattern on weekends and holidays. This spatiotemporal mismatch shows that central urban areas, despite higher station density, can suffer from both high fire risk and low accessibility, revealing structural patterns consistent with the ‘Inverse Care Law’ in emergency service provision. This study concludes that merely improving traffic conditions is insufficient; optimising the spatial matching of resources is paramount for effective urban disaster prevention. By developing a refined dynamic assessment framework, this study advances current knowledge by focusing on demand locations consistent with actual fire regulatory priorities and examining spatiotemporal patterns across both urban and suburban areas, thereby providing quantitative, evidence-based support for the strategic planning of fire stations and the enhancement of infrastructure resilience. Full article

Current diagnostic modalities for rheumatoid arthritis (RA), such as Magnetic Resonance Imaging (MRI) and ultrasound (US), excel at visualizing structural pathology but are either resource-intensive or often limited to morphological assessment. In this work, we present the design and technical validation of a low-cost continuous-wave near-infrared (NIR) dual-mode optical probe for functional monitoring of joint inflammation. Unlike superficial imaging, NIR light penetrates approximately 3–5 cm and is tissue and wavelength dependent, enabling trans-illumination of the synovial volume. The system combines reflectance and transmission geometries to resolve the ambiguity between disease presence and disease severity. To validate the diagnostic logic, we employed mcxyzn Monte Carlo (MC) simulations to model the optical signature of RA progression from early onset to EULAR-OMERACT grade 2 pannus hypertrophy on a simplified finger model, based on several tissue models in the literature and supported by physical measurements on a multilayer silicone phantom and in vivo signal verification on human volunteers. Our results demonstrate a distinct functional dichotomy: reflectance geometry serves as a binary discriminator of synovial turbidity onset, while transmission flux serves as a monotonic proxy for pannus volume, exhibiting a quantifiable signal decay consistent with the Beer–Lambert law. Signal verification on a subject with confirmed RA pathology demonstrated a significant increase in the effective attenuation coefficient (${\mu }_{eff} ~ 0.59$ mm⁻¹) compared to the healthy baseline (${\mu }_{eff} ~ 0.47$ mm⁻¹). Furthermore, simulation analysis revealed a critical “metric inversion” in darker skin phenotypes (Fitzpatrick V–VI), where the standard beam-broadening signature of inflammation is artificially suppressed by epidermal absorption. We conclude that while transmission flux remains a robust grading metric across diverse skin tones, morphological beam-shape metrics are not robust, particularly in high-absorption populations. By targeting the hemodynamic precursors of structural damage, this dual-mode probe design offers a potential pathway for longitudinal, quantitative monitoring of disease activity at the point of care, while the systematic use of the Monte Carlo framework provides insight into the measurement geometry most suitable for a given clinical endpoint, whether that be detecting the presence or severity of rheumatoid arthritis. Full article

The purpose of this work is twofold: first, it aims to derive an exact analytical form of the Pareto index based on the already developed model of the economy as a scale-free network comprising a given amount of either wealth or income (total number of links, each link representing a non-zero amount or quantum of income or wealth) distributed among its variable number of actors (nodes), all of whom have equal access to the system), and second, it aims to employ the derived analytical form of the Pareto index to determine the degree to which the observed inequality in wealth and in income as measured by the respective empirical values of the Pareto index is inherent in the economic system rather than the result of externally imposed factors invariably reflecting a lack of equal access. The derived analytical form of the Pareto index for wealth or for income is described by an exponential function whose exponent is the inverse of the average number of wealth or of income per actor (one-half of the average number of links per node) in the economic model. This exponent features prominently in the scale-free model of the economy and has a numerical value of 0.69 when the Pareto index attains a numerical value of 2, which signifies the optimal, albeit still unequal, distribution of wealth or of income in the economy under the condition of equal access. Because of the correspondence of the scale-free model of the economy to a physical system comprising quantum particles such as photons in thermodynamic equilibrium or state of maximum entropy in accordance with the laws of statistical mechanics, the inverse of the exponent is proportional to the temperature of the economic system, and a new parameter introduced to describe in a comprehensible manner the deviation in the economic system from its optimal distribution of wealth or income. A comparison of the empirical wealth and income Pareto indexes based on economic data for the four largest economies in the word, i.e., USA, China, Germany, and Japan, which account for over 50% of the global GDP, versus the corresponding optimal values per the scale-free model of the economy reveals interesting trends that can be explained away by the prevailing degrees of equal access, as manifested by inadequate education, health care, and housing, as well as the existence of rules and institutions favoring certain actors over others, particularly with regard to the accumulation of wealth. It has also been determined that the newly introduced parameters in the scale-free model of the economy of temperature as well as the quanta of wealth and of income should be expressed in power purchase exchange rates for meaningful comparisons among national economies over time. Full article

An overview is presented of several diverse branches of work in the area of effectively 2D fluid equilibria which have in common that they are constrained by an infinite number of conservation laws. Broad concepts, and the enormous variety of physical phenomena that can be explored, are highlighted. These span, roughly in order of increasing complexity, Euler flow, nonlinear Rossby waves, 3D axisymmetric flow, shallow water dynamics, and 2D magnetohydrodynamics. The classical field theories describing these systems bear some resemblance to perhaps more familiar fluctuating membrane and continuous spin models, but the fluid physics drives these models into unconventional regimes exhibiting large scale jet and eddy structures. From a dynamical point of view these structures are the end result of various conserved variable forward and inverse cascades. The resulting balance between large scale structure and small scale fluctuations is controlled by the competition between energy and entropy in the system free energy, in turn highly tunable through setting the values of the conserved integrals. Although the statistical mechanical description of such systems is fully self-consistent, with remarkable mathematical structure and diversity of solutions, great care must be taken because the underlying assumptions, especially ergodicity, can be violated or at minimum lead to exceedingly long equilibration times. Generalization of the theory to include weak driving and dissipation (e.g., non-equilibrium statistical mechanics and associated linear response formalism) could provide additional insights, but has yet to be properly explored. Full article

Virtual care spread rapidly at the outbreak of the COVID-19 pandemic. Restricting in-person contact contributed to reducing the spread of infection and saved lives. However, the benefits of virtual care were not evenly distributed within and across social groups, and existing inequalities became exacerbated for those unable to fully access to, or benefit from virtual services. This “perspective” paper discusses the extent to which challenges in virtual care access and use in the context of COVID-19 follow the Inverse Care Law. The latter stipulates that the availability and quality of health care is inversely proportionate to the level of population health needs. We highlight the inequalities affecting some disadvantaged populations’ access to, and use of public and private virtual care, and contrast this with a utopian vision of technology as the “solution to everything”. In public and universal health systems, the Inverse Care Law may manifests itself in access issues, capacity, and/or lack of perceived benefit to use digital technologies, as well as in data poverty. For commercial “Direct-To-Consumer” services, all of the above may be encouraged via a consumerist (i.e., profit-oriented) approach, limited and episodic services, or the use of low direct cost platforms. With virtual care rapidly growing, we set out ways forward for policy, practice, and research to ensure virtual care benefits for everyone, which include: (1) pay more attention to “capabilities” supporting access and use of virtual care; (2) consider digital technologies as a basic human right that should be automatically taken into account, not only in health policies, but also in social policies; (3) take more seriously the impact of the digital economy on equity, notably through a greater state involvement in co-constructing “public health value” through innovation; and (4) reconsider the dominant digital innovation research paradigm to better recognize the contexts, factors, and conditions that influence access to and use of virtual care by different groups. Full article

The present study provides a solvent-free organic synthesis of quaternary ammonium salts: bis(2-hydroxyethyl)dimethylammonium taurate ([BHEDMA][Tau]) and bis(2-hydroxyethyl)dimethylammonium acetate ([BHEDMA][OAc]). These ionic compounds are promising materials for carbon dioxide capture processes, as mono sorbents, supplemental components in the conventional process of chemical absorption, and in the combined membrane approach for improving sorption efficiency. The synthesized compounds were characterized by ¹H NMR and FT-IR spectroscopies and elemental analysis. Afterward, the sorption properties of the compounds were evaluated using the inverse gas chromatography (IGC) method, and their thermodynamic parameters were calculated in the temperature range of 303.15–333.15 K. The enthalpy change (∆_sH) was less than 80 kJ·mol⁻¹, indicated by the physical nature of sorption and also proved by FT-IR. Henry’s law constant in regard to carbon dioxide at 303.15 K was equal to 4.76 MPa for [BHEDMA][Tau], being almost 2.5 lower than for [BHEDMA][OAc] (11.55 MPa). The calculated carbon dioxide sorption capacity for [BHEDMA][Tau] and [BHEDMA][OAc] amounted to 0.58 and 0.30 mmol·g⁻¹, respectively. The obtained parameters are comparable with the known solid sorbents and ionic liquids used for CO₂ capture. However, the synthesized compounds, combining the advantages of both alkanolamines and ionic liquids, contain no fluorine in their structure and thus match the principles of environmental care. Full article

Background: There are approximately two billion workers in the informal economy globally. Compared to workers in the formal economy, these workers are often marginalised with minimal or no benefits from occupational health and safety regulations, labour laws, social protection and/or health care. Thus, informal economy workers may have higher occupational health risks compared to their formal counterparts. Our objective was to systematically review and meta-analyse evidence on relative differences (or inequalities) in health services use and health outcomes among informal economy workers, compared with formal economy workers. Methods: We searched PubMed and EMBASE in March 2020 for studies published in 1999–2020. The eligible population was informal economy workers. The comparator was formal economy workers. The eligible outcomes were general and occupational health services use, fatal and non-fatal occupational injuries, HIV, tuberculosis, musculoskeletal disorders, depression, noise-induced hearing loss and respiratory infections. Two authors independently screened records, extracted data, assessed risk of bias with RoB-SPEO, and assessed quality of evidence with GRADE. Inverse variance meta-analyses were conducted with random effects. Results: Twelve studies with 1,637,297 participants from seven countries in four WHO regions (Africa, Americas, Eastern Mediterranean and Western Pacific) were included. Compared with formal economy workers, informal economy workers were found to be less likely to use any health services (odds ratio 0.89, 95% confidence interval 0.85–0.94, four studies, 195,667 participants, I² 89%, low quality of evidence) and more likely to have depression (odds ratio 5.02, 95% confidence interval 2.72–9.27, three studies, 26,260 participants, I² 87%, low quality of evidence). We are very uncertain about the other outcomes (very-low quality of evidence). Conclusion: Informal economy workers may be less likely than formal economy workers to use any health services and more likely to have depression. The evidence is uncertain for relative differences in the other eligible outcomes. Further research is warranted to strengthen the current body of evidence and needed to improve population health and reduce health inequalities among workers. Full article

Unpaid family caregivers must consider the economic trade-off between caregiving and paid employment. Prior literature has suggested that labor force participation (LFP) declines with caregiving intensity, but no study has evaluated this relationship by accounting for the presence of both kinks and discontinuities. Here we used respondents of the China Health and Retirement Longitudinal Study baseline survey who were nonfarming, of working age (aged 45–60) and had a young grandchild and/or a parent/parent-in-law. For women and men separately, a caregiving threshold-adjusted probit model was used to assess the association between LFP and weekly unpaid caregiving hours. Instrumental variables were used to rule out the endogeneity of caregiving hours. Of the 3718 respondents in the analysis, LFP for men was significantly and inversely associated with caregiving that involved neither discontinuities nor kinks. For women, a kink was identified at the caregiving threshold of eight hrs/w such that before eight hours, each caregiving hour was associated with an increase of 0.0257 in the marginal probability of LFP, but each hour thereafter was associated with a reduction of 0.0014 in the marginal probability of LFP. These results have implications for interventions that simultaneously advance policies of health, social care and labor force. Full article

We examined the influencing factors of the undermet care needs of the Chinese disabled oldest old people when their children are both caregivers and are themselves older people. Data were obtained from a cross-sectional survey: the Chinese Longitudinal Healthy Longevity Survey (CLHLS) in 2018. The study participants included 1617 disabled oldest old people whose primary caregiver were their children or children-in-law and were aged 60 years and over. The results showed that the prevalence of undermet needs remained high, with 49.6% disabled oldest old people reporting undermet care needs. Binary logistic regression analysis revealed that living in a rural area (OR = 1.309, 95% CI = 1.133–1.513) and a higher frailty index (OR = 1.103, 95% CI = 1.075–1.131) were significantly positively associated with higher odds for undermet care needs, while a higher annual household income (OR = 0.856, 95% CI = 0.795–0.923), more financial support from children (OR = 0.969, 95% CI = 0.941–0.997), higher care expenditures (OR = 1.044, 95% CI = 1.002–1.088), better caregiver’s performance (OR = 0.282, 95% CI = 0.196–0.407) and sufficient income to pay for daily expenses (OR = 0.710, 95% CI = 0.519–0.973) were significantly inversely associated with higher odds for undermet care needs. This evidence suggests the importance of policies to establish a community-based socialized long-term care system and supporting family caregivers of the disabled oldest old people. Full article

The Inverse Care Law is principally concerned with the effect of market forces on health care which create inequities in access to health services through privileging individuals who possess the forms of social capital that are valued within health care settings. The fields of disaster risk reduction need to consider the ways in which inequities, driven by economic and social policy as well as institutional decision-making, create vulnerabilities prior to a disaster, which are then magnified post disaster through entrenched structural differences in access to resources. Drawing on key principles within the Inverse Care Law, the Inverse Response Law refers to the idea that people in lower socio-economic groups are more likely to be impacted and to experience disparities in service provision during the disaster response and recovery phase. In a market model of recovery, vulnerable groups struggle to compete for necessary services creating inequities in adaptive capacity as well as in social and wellbeing outcomes over time. Both the Inverse Care Law and the Inverse Response Law focus on the structural organisation of services at a macro level. In this article, the Inverse Care Law is outlined, its application to medical treatment following disasters considered and an explanation of the Inverse Response Law provided. Case studies from recent disasters, in London, New Zealand, Puerto Rico and Mexico City are examined in order to illustrate themes at work relating to the Inverse Response Law. Full article

The Sendai Framework for Disaster Risk Reduction (2015) is a global strategy for addressing disaster risk and resilience that has been ratified by member countries of the United Nations. Its guiding principles emphasise building resilience through inter-sectoral collaboration, as well as partnerships that facilitate community empowerment and address underlying risk factors. Both public health and the emergency management sector face similar challenges related to developing and implementing strategies that involve structural change, facilitating community resilience and addressing individual risk factors. Familiarity with public health principles enables an understanding of the holistic approach to risk reduction that is outlined within the Sendai Framework. We present seven concepts that resonate with contemporary public health practice, namely: the social determinants of health; inequality and inequity; the inverse care law; community-based and community development approaches; hard to reach communities and services; the prevention paradox; and the inverse prevention law. These ideas from public health provide a useful conceptual base for the ”new” agenda in disaster risk management that underpins the 2015 Sendai Framework. The relevance of these ideas to disaster risk management and research is illustrated through drawing on the Sendai Framework, disaster literature and exemplars from the 2010–2011 earthquakes in Canterbury, New Zealand. Full article