Search Results (18,544)

The effect of reversible addition–fragmentation chain transfer (RAFT) polymerization on the structure, morphology, and thermal degradation behavior of polypropylene glycol maleate–acrylic acid copolymers (p-PGM:AA) was investigated using 2-cyano-2-propyl dodecyl trithiocarbonate (CPDT) as the RAFT agent. Copolymers synthesized at different CPDT concentrations were characterized by ¹H/¹³C NMR spectroscopy, gel permeation chromatography (GPC), transmission electron microscopy (TEM), thermogravimetric analysis coupled with mass spectrometry (TG–MS), isoconversional kinetic methods, and density functional theory (DFT) calculations. ¹H NMR spectroscopy revealed a progressive decrease in the relative intensity of vinyl proton signals with increasing CPDT concentration, indicating enhanced conversion of unsaturated fragments during copolymerization. Alkaline hydrolysis followed by ¹H NMR and GPC analysis of the degradation products confirmed cleavage of polyester segments and yielded low-molecular-weight fragments with M_n = 1370 g mol⁻¹ and narrow dispersity (Đ = 1.035), providing additional information on the architecture of the vinyl-polymerized segments. Increasing CPDT concentration resulted in lower molecular weights and narrower molecular weight distributions of the soluble copolymer fractions. TEM analysis demonstrated broader domain size distributions and increased morphological heterogeneity in RAFT-modified samples, accompanied by an increase in swelling degree. Thermogravimetric analysis showed that RAFT-modified systems undergo multi-stage thermal degradation with the appearance of an additional low-temperature stage associated with thermolabile fragments. TG–MS revealed earlier evolution of CO₂ and oxygen-containing species and changes in the distribution of volatile products. DFT calculations indicated a decrease in the HOMO–LUMO energy gap and suggested the participation of RAFT-derived fragments in the energetic characteristics of decarboxylation processes. Isoconversional and nonlinear kinetic analyses demonstrated increased kinetic heterogeneity for branched copolymer s synthesized at elevated CPDT concentrations, whereas cross-linked systems exhibited more uniform degradation behavior. The combined experimental and theoretical results demonstrate that RAFT polymerization provides an effective route for tuning the macromolecular architecture, morphology, and thermal degradation pathways of p-PGM:AA copolymers. Full article

Background/Objectives: To investigate the immediate regulatory effects of magnetic stimulation with different parameters on the excitability of glutamatergic neurons and GABAergic neurons in the mouse hippocampal dentate gyrus (DG), and to analyze the underlying mechanisms using the Hodgkin–Huxley (HH) model. Methods: Whole-cell patch-clamp recordings were performed on acute brain slices to measure changes in resting membrane potential (RMP), the number of action potentials (APs) evoked by 500-ms long-duration stimulation, as well as AP threshold, peak, half-width, maximum rising slope, and maximum falling slope under magnetic stimulation at various frequencies (1, 10, 20 Hz) and intensities (50, 75 mT). An improved HH model was established based on experimental data to analyze the dynamic changes in gating variables under magnetic stimulation. Results: High-frequency magnetic stimulation (10–20 Hz) significantly increased the number of APs in both neuron types. In glutamatergic neurons, the number of APs increased from 10.12 ± 0.52 in the control group to 15.62 ± 0.84 in the 20 Hz-75 mT group; in GABAergic neurons, it increased from 7.88 ± 0.40 to 12.62 ± 0.53. Magnetic stimulation also depolarized RMP and significantly altered multiple AP waveform parameters in both neuron types. Glutamatergic neurons showed a more distinct frequency dependence, whereas GABAergic neurons were more sensitive to changes in both frequency and intensity in terms of RMP and multiple waveform parameters. Simulation results showed that the 1 Hz conditions produced negligible changes in AP firing, gating-variable dynamics, and steady-state ion-channel parameters compared with the Control condition. In contrast, high-frequency stimulation enhanced the dynamic changes of sodium and potassium channel gating variables and altered their voltage-dependent steady-state properties. Specifically, sodium channel activation shifted toward more negative potentials, whereas sodium channel inactivation and potassium channel activation shifted toward more depolarized potentials. Conclusions: Under the experimental conditions of this study, magnetic stimulation immediately enhanced the excitability of glutamatergic and GABAergic neurons in the hippocampal dentate gyrus of male mice in a frequency-dependent manner. The modified HH model reproduced both the weak effects under low-frequency stimulation and the enhanced excitability under high-frequency stimulation, suggesting that these immediate effects may be related to frequency-dependent changes in the gating kinetics and voltage-dependent properties of sodium and potassium channels. Full article

This review examines the relationship between climate-driven heat stress (HS) and bovine mastitis in the Po Valley, a key European dairy region characterized by intensive production systems and increasing climatic vulnerability. It aims to contextualize how rising temperature–humidity index (THI) levels influence animal health and productivity. This study synthesizes the current literature on biometeorological conditions, epidemiological trends, and physiological mechanisms linking HS to mastitis. Evidence indicates that prolonged exposure to elevated THI impairs thermoregulation, disrupts endocrine and metabolic balance, and weakens immune function, thereby increasing susceptibility to intramammary infections. Epidemiological data reveal a clear seasonal pattern, with mastitis incidence peaking during summer months and a growing predominance of environmental pathogens. Additionally, HS negatively affects milk yield and quality, amplifying economic losses in dairy systems. The findings highlight that mastitis in this context is not merely an infectious disease but a multifactorial condition shaped by environmental, physiological, and management factors. Overall, this review underscores the need for integrated mitigation strategies, including improved housing, nutrition, genetic selection, and precision monitoring, to enhance resilience. In the face of ongoing climate change, adapting dairy production systems will be essential to safeguard animal welfare, maintain productivity, and ensure the long-term sustainability of the Po Valley dairy sector. Full article

Due to the memory and non-local characteristics of fractional calculus, fractional-order tracking differentiator (FOTD) performs excellently in suppressing impulse noise. However, the parameters of FOTD need to be manually adjusted according to the scene requirements, and cannot automatically maintain optimal performance in scenarios where the signal and noise intensities change dynamically. To address this issue, this paper proposes a multi-parameter optimization-driven FOTD (OFOTD) based on envelope entropy, enhancing the adaptability of FOTD in complex scenarios. Furthermore, a fractional multisynchrosqueezing transform (FRMSST) is developed, and OFOTD-FRMSST is established to accurately represent the signal under impulsive noise. Finally, OFOTD-FRMSST is applied to parameter estimation of linear frequency modulation (LFM) signal, demonstrating its superiority in accuracy, noise robustness, and practicality. Experimental results demonstrate that, from both time domain and time-frequency plane, OFOTD achieves enhanced noise suppression performance through adaptive parameter optimization. Furthermore, in comparison with existing methods, OFOTD-FRMSST yields a more accurate signal representation under impulsive noise, thereby improving accuracy and noise robustness of parameter estimation. Full article

This paper focuses on the analysis of long-term land surface temperature (LST) dynamics and land-use changes in the city of Košice, Slovakia, during the period 1985–2025. The analysis is based on multi-temporal Landsat satellite imagery processed within a geographic information system (GIS) environment. Non-parametric statistical methods, including the Mann–Kendall trend test and the Theil–Sen slope estimator, were applied at the pixel level to identify the direction, magnitude, and statistical significance of long-term trends. Land-use changes were evaluated using CORINE Land Cover data together with the NDVI and NDBI spectral indices. The results revealed a statistically significant increase in land surface temperature across almost the entire urban area, with the mean LST increasing by 5.83 °C between 1985 and 2025. The analysis also confirmed a strong positive correlation between built-up areas and LST values, whereas vegetation cover exhibited a significant cooling effect represented by a strong negative correlation with surface temperature. Spatial analysis identified pronounced warming hotspots concentrated mainly in industrial and newly urbanized areas, while vegetation-stabilized zones showed lower warming intensity or localized cooling trends. The findings highlight the dominant influence of urbanization processes on the city’s thermal regime and emphasize the importance of urban vegetation as a key adaptation element for mitigating the surface urban heat island effect. The study also illustrates the added value of integrating remote sensing data, GIS tools, and pixel-based trend analysis in the assessment of long-term changes in the urban thermal environment of medium-sized Central European cities. The results provide a spatial basis for climate adaptation planning and future assessments of urban thermal comfort and environmental quality. Full article

Reliable rainfall information is fundamental for climate-risk analysis and operational monitoring in Mediterranean regions such as Apulia (Southern Italy), one of the areas most affected by climate change-driven shifts in rainfall patterns. Recent evaluations across Italy and comparable Mediterranean settings consistently show that gridded precipitation performance is highly dependent on orography and dataset typology: reanalyses often provide the best overall agreement with gauges, while satellite and blended products can exhibit larger biases, with persistent challenges in complex terrain and for high-intensity events. In this context—and given the documented spatial heterogeneity of rainfall extremes within Apulia—validation of such gridded datasets with respect to ground observations remains essential for early warning and climatological applications. In the present work, we evaluate four widely used precipitation products—CHIRPS-v2, the newly released CHIRPS-v3, IMERG, and ERA5—benchmarking them against the Apulia region Civil Protection rain-gauge network. We provide diagnostics aligned with early warning and climate monitoring: bias and error statistics, rainfall intensity distributions, and dry spell duration. A key contribution is, to our knowledge, the first dedicated validation of CHIRPS-v3 in Apulia, which is timely given that CHIRPS-v3 was explicitly developed to address shortcomings such as underestimated temporal variance and to leverage expanded station inputs. The results indicate that CHIRPS-v3 yields systematic improvements over CHIRPS-v2 across multiple metrics, while ERA5 generally shows the strongest overall agreement with gauges—consistent with broader Italian evidence. Full article

In this paper, a reconfigurable multi-form radar compound coherent jamming signal generator is proposed based on a dual-polarization quadrature phase shift keying (DP-QPSK) modulator cascaded with an intensity modulator (IM). The radar signal and jamming seed signal are loaded on the upper path and the lower path of the DP-QPSK modulator to achieve carrier-suppressed single-sideband (CS-SSB) modulation and phase modulation, respectively. The periodic rectangular pulse (PRP) signal is fed into the IM to achieve interrupted-sampling repeater jamming in the optical domain. In our proposed scheme, cosine phase modulation and interrupted-sampling repeater jamming (CPMJ-ISRJ) and frequency shift and interrupted-sampling repeater jamming (FSJ-ISRJ) are obtained only by changing the form of the jamming seed signal, without changing the overall structure of the scheme. The jamming effectiveness of the above schemes is evaluated through simulation. Multiple false targets are obtained after cross-correlation with the original radar signal. The number of generated false targets can reach 18. We also conducted a detailed simulation to analyze the impact of different parameters on the jamming effect. Because the scheme is filter-free, it has a large frequency tuning range. Moreover, due to the special CS-SSB modulation, the modulated signals are immune to the chromatic dispersion-induced power fading effect. The proposed scheme has potential application prospects in future electronic countermeasure systems. Full article

The transition from MIS3 interstadial to the coldest stadial of the last glacial (MIS 2) marked a rapid change in the climate. Findings of multiproxy (sedimentological, MS, geochemical (AAS, XRD), micromorphological, anthracological, phytolith and malacological) studies from a loess/paleosol sequence in northeastern Hungary highlighted the transformation of a reddish-brown fossil soil layer (cambisol) to a podzolic soil with signs of iterative wildfires during the terminal part of MIS3. According to our findings, a Scots pine (Pinus sylvestris) dominated open parkland emerged on the northern slopes during the second phase of MIS3 hosted by a special reddish-brown soil. Then the last phase of MIS3 was marked by the development of spruce (Picea abies) dominated open parkland. Results further suggest that vegetation change passed a critical threshold leading to an unusually rapid expansion of spruce (within ca. 100 yr). This rapid expansion of spruce, changing the geochemistry of the litter to a more acidic state likely caused the initiation of podzolization and the transformation of the original soil. The opening of MIS2 marked not only intensive dust accumulation but also a steady decline of arboreal elements as well, leading to the emergence of a cold tundra on top of the podosol with charcoal remains. Full article

In protected areas, fragmentation and artificial light at night are usually present alongside changes in land type, from natural to agricultural or urban. We explored the intensity of edge effects on light trap responses of nocturnal insects at the margin of the floodplain forest in the Donau-Auen National Park in Central Europe, Austria. Specifically, we examined the abundance and biomass of nocturnal insects and characterized the community composition and diversity of moths with respect to the local habitat. In this study, 58 species were observed, with 21 unique records on the forest edge and nine in the interior. Traps in the forest interior harbored significantly higher nocturnal insect biomass. However, moth assemblages were more diverse at edge sites due to many singletons, attributed to individuals attracted from areas with open vegetation. Nine species (15.5% of total) were recorded later than expected given their summer flight periods, potentially reflecting the effects of ongoing climate change associated with warmer autumns. Overall, we observed higher moth species diversity at the forest edge, and insect biomass and moth abundance were higher within the forest. These findings underscore the urgent need to incorporate local anthropogenic landscape and climate change as synergically evolutionary drivers in future population and community-focused research. Full article

The urban heat island (UHI) effect has become a prominent ecological and energy challenge amid rapid urbanization. This study comprehensively examined the spatiotemporal dynamics of UHI intensity in built-up areas across 216 Chinese cities spanning five climatic zones from 2000 to 2020 and quantified UHI-triggered energy consumption, as well as revealing its driving mechanisms. The results showed a significant increasing trend in UHI intensity across China’s urban built-up areas during summer days, summer nights, and winter nights from 2000 to 2020, with corresponding annual growth rates of 10.23, 5.61, and 5.08 km²·°C·a⁻¹, respectively. However, winter daytime UHI intensity declined dramatically from 4.72 °C in 2000 to −10.21 °C in 2020, which can be attributed to the reduction in socioeconomic activities during the COVID-19 period. UHI intensity intensified significantly across all climate zones, with the largest increases observed in the middle temperate zone and warm temperate zone, reaching 127.23 km²·°C and 116.04 km²·°C, respectively. Spatially, 39.8% of the 216 cities exhibited a significant increasing trend in UHI intensity, while only 2.8% showed a decreasing trend. After 2005, the contribution of large cities to UHI intensity continued to rise, reaching 54% in 2020. This study estimated UHI-induced energy consumption in terms of standard coal equivalent, with the northern and middle subtropical zones jointly accounting for over 61.9% of the annual average consumption. Regression results confirmed that impervious surface expansion served as the dominant positive driver of UHI, while vegetation coverage exerted a strong cooling effect. These findings can facilitate the formulation of region-specific UHI mitigation and energy conservation policies for cities under different climatic conditions and at diverse development scales. Mechanistic analysis further revealed that variations in impervious surface area dominated the rise in UHI intensity, whereas changes in the normalized difference vegetation index exerted a significant mitigating effect. These findings provide a solid scientific basis for targeted UHI mitigation and energy-saving management strategies for cities across different climate zones and urban scales. Full article

Decadal changes in the community structure of coral reef-associated fishes reflect prevailing poor environmental conditions. This study analyzed temporal shifts in fish communities (e.g., diversity, density, and biomass) recorded via SCUBA belt transects across coral reefs on the center–southern coast of Quintana Roo (eastern Yucatan Peninsula) in the Mexican Caribbean. Sites were initially investigated in 1995 and revisited in 2024 after the construction of a cruise ship pier, and we compared sites under different protection categories. Mean density and biomass decreased significantly over time, particularly at reef sites outside of a protected area in 1995. While species richness and density of commercially important fishes were higher in protected sites in 1995, parrotfishes (Scarinae) maintained stable density and biomass across both years and protection status. No significant differences were found in the biomass of other fishes (e.g., Haemulidae, Lutjanidae). Changes recorded may reflect historical fishing pressure, including poaching, but probably also pollution from intense growth of coastal tourism infrastructure in 2024, as well as damage from the beached Sargassum influx. Ultimately, the positive effect offered by protected areas is not enough to mitigate the local and regional environmental impacts on coral reefs. Our findings serve as a reference point where coastal development and climate change interact and affect coral reefs. Full article

Background and Objectives: Knee osteoarthritis (KOA) and other degenerative chondropathies are major causes of pain and disability. When core conservative treatments are insufficient, intra-articular hyaluronic acid (HA) and platelet-rich plasma (PRP) are commonly used as adjunctive options, although evidence remains difficult to interpret because of heterogeneity in patients, products, preparation protocols, and treatment schedules. This exploratory retrospective study described short-term clinical outcomes after two standardized intra-articular protocols, hybrid HA and autologous PRP, in a real-world outpatient physiatry setting. Materials and Methods: This monocentric retrospective study included 40 treated knees (19 HA, 21 PRP) from 31 unique patients at the Policlinico di Bari between October 2022 and November 2024. The HA group received two injections of a hybrid high-/low-molecular-weight HA formulation, whereas the PRP group received three injections of autologous PRP. Outcomes were pain intensity, assessed by the Numerical Rating Scale (NRS), and function, assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), from baseline to end-of-cycle follow-up. Results: Both groups showed short-term clinical improvement. Mean NRS scores decreased from 6.26 to 2.26 in the HA group and from 6.76 to 2.29 in the PRP group, with no significant between-group difference in change from baseline (p = 0.509). WOMAC improved by 25.42 ± 20.39 points in the HA group and 20.19 ± 16.18 points in the PRP group (p = 0.372). In the main regression analysis, treatment type was not a significant predictor of outcome; unadjusted and age-/sex-adjusted WOMAC sensitivity models suggested a possible HA advantage that was not retained after full adjustment. Conclusions: In this small exploratory cohort, both protocols were associated with short-term improvements, without definitive fully adjusted evidence of between-group superiority. These findings should not be interpreted as evidence of equivalence or definitive comparative efficacy. Full article

Behavior change technologies are increasingly deployed in everyday contexts where perception errors are difficult to avoid. Such errors can undermine user trust and long-term engagement, while purely technical approaches to error elimination are often impractical in open-world environments. This study proposes a fault-tolerant design that translates algorithmic uncertainty into anthropomorphic expressions of vulnerability. By decoupling task-outcome feedback from internal confidence states, an embodied agent communicates uncertainty through a five-level nonverbal framework comprising posture, facial expression, and motion intensity. The approach was implemented in an interactive waste-sorting system and examined through a three-week field study in a semi-public university corridor. Three feedback strategies were compared: an outcome-only baseline, a persistently confident agent, and an adaptive agent whose vulnerability expression varied according to a transformed confidence signal. The findings suggest differences in user behavior across conditions. Under the adaptive condition, user sorting accuracy exhibited a fluctuation–recovery pattern during the final deployment phase, whereas accuracy under the confident-agent condition showed a declining trend. Correct-trial stay durations were shorter under the adaptive condition, consistent with the formation of a more streamlined interaction routine. In contrast, observations from error cases were limited by the small number of misclassification events. Due to the exploratory nature of the study, the small sample size of the questionnaire and the sequential deployment structure, the results should be considered preliminary evidence. Nevertheless, the findings suggest that expressing vulnerability in an anthropomorphic way may be a promising approach for communicating uncertainty in behavior change systems. Full article

Under the “dual carbon” goals, Taiyuan, a prefecture-level administrative unit and energy-intensive region in Shanxi Province, China, has experienced changes in soil carbon storage and soil carbon flux under rapid urbanization and industrialization. To clarify the spatial patterns of soil carbon storage and flux, 26 field sampling sites, including 78 soil samples, were analyzed using laboratory measurements and an optimized tunable diode laser absorption spectroscopy–geographic information system (TDLAS–GIS) integrated monitoring approach. This study investigated the spatial patterns of soil carbon storage and flux and discussed their potentially associated factors, providing an exploratory workflow for regional carbon monitoring. The results showed clear spatial heterogeneity, with an average soil organic carbon (SOC) content of 10.86 g/kg. High-SOC areas were mainly located in the southern and southwestern plains, while lower SOC levels occurred in urban expansion zones and highly disturbed surfaces. The western mountainous areas were important ecological barriers but were not the highest measured SOC zones. At the site level, arable land and forestland showed higher mean SOC values than grassland, with average SOC contents of 12.47, 12.07, and 8.27 g/kg, respectively, although these land-use-related differences were not statistically significant. Soil carbon flux was relatively higher in some mountainous regions and industrial–ecological transition areas but lower in several urban expansion areas. The results suggest that urbanization and industrial activity may be associated with changes in SOC and soil-atmosphere CO₂ exchange. This study describes the spatial variation characteristics of soil carbon storage and flux, establishes a reproducible TDLAS–GIS workflow for regional carbon monitoring, and provides exploratory support for ecological sustainability, sustainable land management, and the “dual carbon” strategy in northern resource-based cities. Full article

In recent decades, residential mobility has emerged as a fundamental interpretative key lens for understanding contemporary urban transformations, particularly in polycentric and fragmented urban contexts. Movements between different residential settings reflect economic, social and cultural changes, impacting the organisation of urban spaces, the demand for services and mobility systems. In territories characterised by dispersed settlement patterns and strong functional polarisation, these dynamics tend to promote the intensive use of private means, with consequent negative impacts on environmental sustainability, social equity and economic efficiency. In response to these critical issues, there is growing interest in sustainable mobility models based on proximity and on the integration between daily travel, access to services and the quality of public space. Within this perspective, greenways are configured as hybrid infrastructures, capable of reorganising mobility while contributing to the regeneration of urban spaces. In the Caserta area, in the Campania region, the disused route of the former Alifana railway represents a topic of great interest, both for research and planning. Its potential strategic conversion into a greenway opens a broader perspective than that so far considered at the regional level, which has mainly focused on the infrastructure dimension. The paper analyses the strengths and weaknesses of an approach limited to infrastructural mobility, proposing a comparative evaluation of project scenarios—including the non-intervention hypothesis—both through the application of the MACBETH approach and preliminary parametric estimation of construction costs, in order to emphasise the importance of integrating social and environmental benefits, as well as quality of life, into decision-making processes. Full article