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16,035 Results Found

  • Article
  • Open Access
9 Citations
4,436 Views
11 Pages

30 August 2021

To establish whether clinical prognostic factor outcomes differed based on the initial severity of facial weakness and to determine the association between the initial severity of facial weakness and favorable outcomes. This retrospective cohort stud...

  • Article
  • Open Access
10 Citations
3,383 Views
9 Pages

Association of the Unstimulated Whole Salivary Cytokine IL-1β Levels with Initial, Moderate and Severe Periodontitis. A Case Control Study

  • Muhammad M. Majeed,
  • Imtiaz Ahmed,
  • Talat Roome,
  • Yasser Alali,
  • Khulud A. Al-Aali,
  • Naseer Ahmed,
  • Zohra Saleem,
  • Abdulkareem A. Alhumaidan,
  • Waqas A. Farooqui and
  • Tariq Abduljabbar
  • + 2 authors

Periodontitis (P) is a highly prevalent inflammatory disease of the oral cavity. The objective of the study was to evaluate the stages of pro-inflammatory cytokine IL-1β in initial, moderate and severe periodontitis. One hundred and twenty two p...

  • Article
  • Open Access
1,291 Views
26 Pages

4 August 2025

Background/Objectives: Children with severe physical and communication disabilities face many challenges. They have very limited opportunities for upright, hands-free, self-initiated mobility. Current findings in neuroscience and theories on child de...

  • Article
  • Open Access
3 Citations
2,223 Views
13 Pages

1 April 2023

(1) Background: We constructed scores for moderate-to-severe and muscle-predominant types of Graves’ orbitopathy (GO) risk prediction based on initial ophthalmic findings. (2) Methods: 400 patients diagnosed with GO and followed up at both endo...

  • Article
  • Open Access
31 Citations
7,104 Views
10 Pages

Effects of Initial Age and Severity on Cranial Remolding Orthotic Treatment for Infants with Deformational Plagiocephaly

  • Tiffany Graham,
  • Beverley Adams-Huet,
  • Nicole Gilbert,
  • Kirsten Witthoff,
  • Terran Gregory and
  • Mary Walsh

24 July 2019

The aim of this study is to review the effects of an infant’s presenting age and severity of deformation on cranial remolding orthotic (CRO) treatment outcomes for patients with deformational plagiocephaly. This study is a retrospective chart review...

  • Feature Paper
  • Article
  • Open Access
20 Citations
8,879 Views
11 Pages

SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) causes a variety of responses in those who contract the virus, ranging from asymptomatic infections to acute respiratory failure and death. While there are likely multiple mechanisms trigge...

  • Article
  • Open Access
1,298 Views
9 Pages

20 November 2024

Objective: We aimed to determine whether the severity of acute Kawasaki disease (KD) can be predicted based on whether a patient remains febrile or becomes afebrile immediately after the completion of initial immunoglobulin treatment (IVIG). Methods:...

  • Article
  • Open Access
1 Citations
900 Views
15 Pages

Association Between Pre-Admission ATRIA Scores and Initial Stroke Severity in Acute Ischemic Stroke: A Cross-Sectional Study

  • Hakan Süygün,
  • Merve Akgül Günay,
  • Damla Yalçınkaya Öner,
  • Enes Çon,
  • Mehmet Mustu,
  • Ahmet Yılmaz,
  • Sümeyye Fatma Ozer,
  • Burçin Daş,
  • Ahmet Karakurt and
  • Özgür Akgul

1 July 2025

Objectives: This study aimed to investigate the relationship between the anticoagulation and risk factors in atrial fibrillation (ATRIA) score and initial stroke severity in patients with acute ischemic stroke of varying etiologies, including atrial...

  • Brief Report
  • Open Access
12 Citations
8,945 Views
6 Pages

Bowel Dilatation on Initial Plane Abdominal Radiography May Help to Assess the Severity of Necrotizing Enterocolitis in Preterm Infants

  • Zlatan Zvizdic,
  • Irmina Sefic Pasic,
  • Amra Dzananovic,
  • Nedzad Rustempasic,
  • Emir Milisic,
  • Asmir Jonuzi and
  • Semir Vranic

23 January 2020

Background: Necrotizing enterocolitis (NEC) is the most common life-threatening gastrointestinal emergency associated with prematurity. Timely diagnosis and adequate treatment are crucial to reduce the morbidity and mortality of the affected infants....

  • Letter
  • Open Access
5 Citations
3,587 Views
11 Pages

How Initial Forest Cover, Site Characteristics and Fire Severity Drive the Dynamics of the Southern Boreal Forest

  • Victor Danneyrolles,
  • Osvaldo Valeria,
  • Ibrahim Djerboua,
  • Sylvie Gauthier and
  • Yves Bergeron

3 December 2020

Forest fires are a key driver of boreal landscape dynamics and are expected to increase with climate change in the coming decades. A profound understanding of the effects of fire upon boreal forest dynamics is thus critically needed for our ability t...

  • Article
  • Open Access
7 Citations
3,148 Views
11 Pages

10 February 2022

Patients with Coronavirus-2019 (COVID-19) manifest many neuromuscular complications. We evaluated the correlations between electromyography and nerve conduction measurements among COVID-19 patients and the severity of the initial infection, as well a...

  • Article
  • Open Access
12 Citations
3,550 Views
17 Pages

Long-Term SARS-CoV-2 Specific Immunity Is Affected by the Severity of Initial COVID-19 and Patient Age

  • Margarethe Konik,
  • Monika Lindemann,
  • Markus Zettler,
  • Lara Meller,
  • Sebastian Dolff,
  • Vera Rebmann,
  • Peter A. Horn,
  • Ulf Dittmer,
  • Adalbert Krawczyk and
  • Hana Rohn
  • + 12 authors

8 October 2021

The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently the greatest medical challenge. Although crucial to the future management of the pandemic, the factors affecting the persi...

  • Article
  • Open Access
1 Citations
1,854 Views
10 Pages

Prognostic Value of Initial Inflammatory Biomarkers, ECG Findings, and Computed Tomography in the Assessment of Acute Pulmonary Embolism Severity

  • Bojana Uzelac,
  • Vladimir Jakovljević,
  • Vladimir Živković,
  • Jelena Janković,
  • Katarina Lazarević,
  • Danilo Marković,
  • Marija Laban-Lazović,
  • Andrija Jovanović,
  • Marina Đikić and
  • Sanja Stanković
  • + 2 authors

13 October 2025

Background and Objectives: Acute pulmonary thromboembolism (PTE) is one of the leading causes of cardiovascular mortality. Recent insights into PTE pathophysiology emphasize the complex interplay of multiple mechanisms, particularly the roles of thro...

  • Article
  • Open Access
3 Citations
1,916 Views
14 Pages

Significance of Initial Chest CT Severity Score (CTSS) and Patient Characteristics in Predicting Outcomes in Hospitalized COVID-19 Patients: A Single Center Study

  • Aleksandra Milenkovic,
  • Simon Nikolic,
  • Zlatan Elek,
  • Jelena Aritonovic Pribakovic,
  • Aleksandra Ilic,
  • Kristina Bulatovic,
  • Milos Gasic,
  • Bojan Jaksic,
  • Milan Stojanovic and
  • Filip Petrović
  • + 4 authors

29 October 2024

The aim of this study is to examine the prognostic role of initial chest computed tomography severity score index (CTSS) and its association with demographic, socio-epidemiological, and clinical parameters in COVID-19 hospitalized patients. A retrosp...

  • Article
  • Open Access
3 Citations
2,752 Views
11 Pages

Maxillary Arch Dimensions in 6-Year-Old Cleft Children in Northern Finland: A Cross-Sectional Study

  • Mirjami Corcoran,
  • Saujanya Karki,
  • Leena Ylikontiola,
  • Riitta Lithovius,
  • George K. Sándor and
  • Virpi Harila

The aim was to cross-sectionally examine the maxillary arch dimensions in 6-year-old children with cleft lip and/or palate and to compare them with the initial cleft sizes among patients with cleft palate. The study included 89 patients with clefts t...

  • Article
  • Open Access
11 Citations
5,095 Views
10 Pages

23 August 2021

Climate driven increases in fire frequency and severity are predicted for Mediterranean climatic zones, including the Pacific coast of California. A recent high severity wildfire that burned in the Santa Cruz Mountains affected a variety of vegetatio...

  • Article
  • Open Access
14 Citations
4,095 Views
18 Pages

Effect of Severe Shot Peening on the Very-High Cycle Notch Fatigue of an AW 7075 Alloy

  • Michal Jambor,
  • Libor Trško,
  • Jan Klusák,
  • Stanislava Fintová,
  • Daniel Kajánek,
  • František Nový and
  • Otakar Bokůvka

18 September 2020

The severe shot peening process was applied to the notched specimens from an AW 7075 alloy with the aim to improve fatigue endurance in the very-high cycle fatigue region. To reveal the stress state in the notch vicinity, finite element analysis was...

  • Feature Paper
  • Article
  • Open Access
47 Citations
3,974 Views
9 Pages

17 April 2021

Clinical reports on early immune dysregulation in acute pancreatitis (AP) are scarce. Herein we investigate the initial temporal development of selected biomarkers. Blood samples were taken at 0–24 and 25–48 h after onsets of AP were acquired. Mean v...

  • Article
  • Open Access
27 Citations
6,155 Views
19 Pages

20 January 2020

Thunderstorms in southeastern South America (SESA) stand out in satellite observations as being among the strongest on Earth in terms of satellite-based convective proxies, such as lightning flash rate per storm, the prevalence for extremely tall, wi...

  • Article
  • Open Access
3 Citations
2,346 Views
26 Pages

A Case Study on the Convection Initiation Mechanisms over the Northern Edge of Tarim Basin, Xinjiang, Northwest China

  • Aerzuna Abulimiti,
  • Qi Sun,
  • Lin Yuan,
  • Yongqiang Liu,
  • Junqiang Yao,
  • Lianmei Yang,
  • Jie Ming and
  • Abuduwaili Abulikemu

3 October 2023

The convection initiation (CI) mechanisms of severe storms have received increasing attention because severe storms have been occurring more frequently around the globe in recent years. In this work, the CI mechanisms of severe convective weather ass...

  • Article
  • Open Access
18 Citations
6,499 Views
20 Pages

Impact of Model Resolution and Initial/Boundary Conditions in Forecasting Flood-Causing Precipitations

  • Francesco Ferrari,
  • Federico Cassola,
  • Peter Enos Tuju,
  • Alessandro Stocchino,
  • Paolo Brotto and
  • Andrea Mazzino

In late summer and autumn Mediterranean coastal regions are quite regularly affected by small-scale, flood-producing convective systems. The complexity of mesoscale triggering mechanisms, related to low-level temperature gradients, moisture convergen...

  • Article
  • Open Access
6 Citations
3,270 Views
11 Pages

Background: In chronic obstructive pulmonary disease (COPD), there are two known classifications for assessing what is called disease severity. One is the Global Initiative for Chronic Obstructive Lung Disease (GOLD) classification, which is based on...

  • Article
  • Open Access
2 Citations
3,149 Views
15 Pages

Depression is a major cause of disability among populations worldwide. Apart from primary symptoms, depressed patients often have a higher cardiovascular risk profile. Multimodal therapy concepts, including exercise, have emerged as promising approac...

  • Article
  • Open Access
11 Citations
4,679 Views
32 Pages

Evaluating a New Relative Phenological Correction and the Effect of Sentinel-Based Earth Engine Compositing Approaches to Map Fire Severity and Burned Area

  • Adrián Israel Silva-Cardoza,
  • Daniel José Vega-Nieva,
  • Jaime Briseño-Reyes,
  • Carlos Ivan Briones-Herrera,
  • Pablito Marcelo López-Serrano,
  • José Javier Corral-Rivas,
  • Sean A. Parks and
  • Lisa M. Holsinger

29 June 2022

The remote sensing of fire severity and burned area is fundamental in the evaluation of fire impacts. The current study aimed to: (i) compare Sentinel-2 (S2) spectral indices to predict field-observed fire severity in Durango, Mexico; (ii) evaluate t...

  • Article
  • Open Access
5 Citations
4,920 Views
25 Pages

Initial Study on COMT and DRD2 Gene Polymorphisms as Well as the Influence of Temperament and Character Trait on the Severity of Alcohol Craving in Alcohol-Dependent Patients

  • Damian Czarnecki,
  • Marcin Ziółkowski,
  • Jan Chodkiewicz,
  • Anna Długosz,
  • Joanna Feldheim,
  • Napoleon Waszkiewicz,
  • Agnieszka Kułak-Bejda,
  • Marta Gorzkiewicz,
  • Jacek Budzyński and
  • Edward Jacek Gorzelańczyk
  • + 8 authors

15 December 2021

The main aim of this work was to determine the impact of COMT and DRD2 gene polymorphisms together with temperament and character traits on alcohol craving severity alcohol-dependent persons. The sample comprised of 89 men and 16 women (aged 38&plusm...

  • Case Report
  • Open Access
948 Views
6 Pages

Severe Nephritis as Initial Sign of Waldenström’s Macroglobulinemia

  • Thomas Knoop,
  • Kristin Kampevold Larsen,
  • Friedemann Leh,
  • Anette Lodvir Hemsing,
  • Ingrid Anna Teigen and
  • Håkon Reikvam

19 December 2019

Waldenström’s macroglobulinemia (WM), characterized with monoclonal immunoglobulins of type M and lymphoplasmacytic lymphoma, is a rare clonal Bcell disorder. WM usually present as an indolent lymphoma, and renal involvement is, in contrast to multip...

  • Case Report
  • Open Access
1 Citations
3,580 Views
6 Pages

29 June 2024

Background: Sarcoidosis is a multisystemic disease that is histologically characterized by non-caseating granulomas in one or more organs. Although hypercalcemia is commonly seen in sarcoidosis, clinically significant hypercalcemia as the initial pre...

  • Article
  • Open Access
1 Citations
2,834 Views
27 Pages

Mapping Soil Burn Severity and Crown Scorch Percentage with Sentinel-2 in Seasonally Dry Deciduous Oak and Pine Forests in Western Mexico

  • Oscar Enrique Balcázar Medina,
  • Enrique J. Jardel Peláez,
  • Daniel José Vega-Nieva,
  • Adrián Israel Silva-Cardoza and
  • Ramón Cuevas Guzmán

5 July 2025

There is a need to evaluate Sentinel-2 (S2) fire severity spectral indices (SFSIs) for predicting vegetation and soil burn severity for a variety of ecosystems. We evaluated the performance of 26 SFSIs across three fires in seasonally dry oak–p...

  • Article
  • Open Access
4 Citations
3,048 Views
12 Pages

12 August 2020

Bacteremia is linked to substantial morbidity and medical costs. However, the association between the timing of achieving hemodynamic stability and clinical outcomes remains undetermined. Of the multicenter cohort consisted of 888 adults with communi...

  • Review
  • Open Access
2,466 Views
12 Pages

Early Initiation of Biologic Therapies to Prevent Severe Asthma Progression

  • Alessandra Tomasello,
  • Alida Benfante,
  • Stefania Principe and
  • Nicola Scichilone

6 October 2025

Asthma is a chronic inflammatory disease with a heterogeneous course, often progressing silently from mild symptoms to severe, treatment-refractory disease. Current guidelines recommend biologic therapies after failure of high-dose inhaled corticoste...

  • Article
  • Open Access
4 Citations
3,509 Views
15 Pages

7 January 2022

We performed a hydrogen combustion analysis in the Advanced Power Reactor 1400 MWe (APR1400) containment during a severe accident initiated by a small break loss of coolant accident (SBLOCA) which occurred at a lower part of the cold leg using a mult...

  • Article
  • Open Access
6 Citations
3,299 Views
12 Pages

Multidrug-Resistant Healthcare-Associated Infections in Neonates with Severe Respiratory Failure and the Impacts of Inappropriate Initial Antibiotic Therap

  • Jen-Fu Hsu,
  • Shih-Ming Chu,
  • Hsiao-Chin Wang,
  • Chen-Chu Liao,
  • Mei-Yin Lai,
  • Hsuan-Rong Huang,
  • Ming-Chou Chiang,
  • Ren-Huei Fu and
  • Ming-Horng Tsai

Background: Multidrug-resistant (MDR) pathogens have emerged as an important issue in neonatal intensive care units (NICUs), especially in critically ill neonates with severe respiratory failure. We aimed to investigate neonatal healthcare-associated...

  • Article
  • Open Access
2 Citations
4,326 Views
12 Pages

Longitudinal Associations between Life Satisfaction and Cannabis Use Initiation, Cessation, and Disorder Symptom Severity in a Cohort of Young Swiss Men

  • Marianthi Lousiana Deligianni,
  • Joseph Studer,
  • Jean-Bernard Daeppen,
  • Gerhard Gmel and
  • Nicolas Bertholet

Motivations for cannabis use may include coping with negative well-being. Life satisfaction, a hallmark of subjective well-being, could play a role in cannabis use among young adults. This study aims to assess whether life satisfaction (SWLS) at age...

  • Article
  • Open Access
22 Citations
4,651 Views
17 Pages

1 August 2017

The decomposition characteristics of a SF6 gas-insulated medium were used to diagnose the partial discharge (PD) severity in DC gas-insulated equipment (DC-GIE). First, the PD characteristics of the whole process were studied from the initial PD to t...

  • Article
  • Open Access
16 Citations
3,291 Views
18 Pages

Evolution of Neuroimaging Findings in Severe COVID-19 Patients with Initial Neurological Impairment: An Observational Study

  • François Lersy,
  • Caroline Bund,
  • Mathieu Anheim,
  • Mary Mondino,
  • Vincent Noblet,
  • Shirley Lazzara,
  • Clelie Phillipps,
  • Olivier Collange,
  • Walid Oulehri and
  • Stéphane Kremer
  • + 12 authors

1 May 2022

Background and Objectives: Cerebral complications related to the COVID-19 were documented by brain MRIs during the acute phase. The purpose of the present study was to describe the evolution of these neuroimaging findings (MRI and FDG-PET/CT) and des...

  • Review
  • Open Access
10 Citations
7,071 Views
18 Pages

To Improve the Initial Inpatient Management of Adolescents Admitted with Severe Anorexia Nervosa: A Narrative Review and a Convenient Protocol

  • Stephanie Proulx-Cabana,
  • Marie-Elaine Metras,
  • Danielle Taddeo,
  • Olivier Jamoulle,
  • Jean-Yves Frappier and
  • Chantal Stheneur

5 January 2022

Inadequate nutritional rehabilitation of severely malnourished adolescents with Anorexia Nervosa (AN) increases the risk of medical complications. There is no consensus on best practices for inpatient nutritional rehabilitation and medical stabilizat...

  • Review
  • Open Access
2,866 Views
16 Pages

Acute Severe Ulcerative Colitis (ASUC): Clinical Features, Initial Management, and the Role of Advanced Therapies

  • Fares Jamal,
  • Marina Ivanov,
  • Sandra Elmasry,
  • Alejandro J. Gonzalez and
  • Talha A. Malik

Acute severe ulcerative colitis (ASUC) is a medical emergency affecting up to 25% of patients with ulcerative colitis (UC), with colectomy required in approximately 25–30% of cases during the initial admission. Intravenous corticosteroids remai...

  • Article
  • Open Access
702 Views
13 Pages

24 March 2025

Introduction: This study presents long-term data of pediatric AIS patients with a favorable initial clinical presentation who were followed by a tertiary pediatric neurology clinic with a well-organized stroke team. Method: Patients who were diagnose...

  • Article
  • Open Access
9 Citations
4,737 Views
18 Pages

Convective Initiation Proxies for Nowcasting Precipitation Severity Using the MSG-SEVIRI Rapid Scan

  • Donatello Gallucci,
  • Maria Pia De Natale,
  • Domenico Cimini,
  • Francesco Di Paola,
  • Sabrina Gentile,
  • Edoardo Geraldi,
  • Salvatore Larosa,
  • Saverio Teodosio Nilo,
  • Elisabetta Ricciardelli and
  • Filomena Romano
  • + 1 author

9 August 2020

In this study, we investigate the ability of several convective initiation predictors based on satellite infrared observations to distinguish convective weak precipitation events from those leading to intense rainfall. The two types of precipitation...

  • Article
  • Open Access
3 Citations
3,649 Views
9 Pages

The Efficacy of Intraosseous Access for Initial Resuscitation in Patients with Severe Trauma: A Retrospective Multicenter Study in South Korea

  • Youngmin Kim,
  • Seung Hwan Lee,
  • Sung Wook Chang,
  • Yo Huh,
  • Sunju Kim,
  • Jeong Woo Choi,
  • Hang Joo Cho and
  • Gil Jae Lee

25 June 2024

Background/Objective: In patients with severe trauma, intraosseous (IO) access is an alternative when intravenous (IV) access proves challenging. However, detailed insights into its utilization patterns and effectiveness are lacking. This study aims...

  • Article
  • Open Access
10 Citations
3,828 Views
10 Pages

10 November 2022

Low body mass index (BMI) is an independent predictor of prolonged hospital stay and mortality in patients with chronic obstructive pulmonary disease (COPD). However, to the best of our knowledge, no studies have examined the validity of Asian BMI cu...

  • Systematic Review
  • Open Access
5 Citations
4,265 Views
11 Pages

27 February 2023

The purpose of this systematic review was to analyze evidence based on existing studies on the ability of initial CT imaging to predict mortality in severe traumatic brain injuries (TBIs) in pediatric patients. An experienced librarian searched for a...

  • Article
  • Open Access
1,608 Views
9 Pages

The purpose: Evaluation of the short-term and long-term results of a phased correction of the tetralogy of Fallot (ToF) with stenting of the right ventricular outflow tract (RVOT) in comparison with a one-stage total correction (TC) of the defect. Ma...

  • Review
  • Open Access
22 Citations
7,345 Views
16 Pages

15 April 2021

Fungi represent one of the most diverse and abundant eukaryotes on earth, and their ubiquity and small proteolytically active products make them pervasive allergens that affect humans and other mammals. The immunologic parameters surrounding fungal a...

  • Review
  • Open Access
3 Citations
7,729 Views
16 Pages

Resuscitation and Initial Management After Moderate-to-Severe Traumatic Brain Injury: Questions for the On-Call Shift

  • Jesús Abelardo Barea-Mendoza,
  • Mario Chico-Fernández,
  • Maria Angeles Ballesteros,
  • Alejandro Caballo Manuel,
  • Ana M. Castaño-Leon,
  • J. J. Egea-Guerrero,
  • Alfonso Lagares,
  • Guillermo Morales-Varas,
  • Jon Pérez-Bárcena and
  • Juan Antonio Llompart-Pou
  • + 1 author

2 December 2024

Traumatic brain injury (TBI) is a leading cause of disability and mortality globally, stemming from both primary mechanical injuries and subsequent secondary responses. Effective early management of moderate-to-severe TBI is essential to prevent seco...

  • Article
  • Open Access
1 Citations
4,640 Views
14 Pages

Intraosseous and Intra-Articular Platelet-Rich Plasma for Severe Knee Osteoarthritis: A Real-World-Outcomes Initiative

  • José Miguel Catalán,
  • Gabriel Escarrer-Garau,
  • Maria del Mar Estrany-Celià,
  • Catalina Parra,
  • Laura Arbona-González,
  • Josep Mercader-Barceló and
  • Severiano Dos-Anjos

22 May 2025

Background/Objectives: The inconsistent clinical outcomes of platelet-rich plasma (PRP) therapy for knee osteoarthritis (KOA) highlight the need to elucidate PRP’s therapeutic potential and influencing factors. Real-world evidence can provide v...

  • Article
  • Open Access
1 Citations
1,209 Views
11 Pages

17 June 2025

Background: Numerous novel medications are being developed to treat moderate to severe atopic dermatitis (AD), notably biologics and Janus kinase inhibitors (JAKis). However, the exact guideline for the first determination of which medication has not...

  • Review
  • Open Access
30 Citations
10,635 Views
31 Pages

(1) Background: Extracorporeal membrane oxygenation (ECMO) is increasingly used for acute respiratory failure with few absolute but many relative contraindications. The provider in charge often has a difficult time weighing indications and contraindi...

  • Review
  • Open Access
29 Citations
7,587 Views
16 Pages

Whole Blood, Fixed Ratio, or Goal-Directed Blood Component Therapy for the Initial Resuscitation of Severely Hemorrhaging Trauma Patients: A Narrative Review

  • Mark Walsh,
  • Ernest E. Moore,
  • Hunter B. Moore,
  • Scott Thomas,
  • Hau C. Kwaan,
  • Jacob Speybroeck,
  • Mathew Marsee,
  • Connor M. Bunch,
  • John Stillson and
  • Quincy K. Tran
  • + 6 authors

17 January 2021

This narrative review explores the pathophysiology, geographic variation, and historical developments underlying the selection of fixed ratio versus whole blood resuscitation for hemorrhaging trauma patients. We also detail a physiologically driven a...

  • Article
  • Open Access
35 Citations
5,676 Views
16 Pages

A Randomized Trial of Deep Brain Stimulation to the Subcallosal Cingulate and Nucleus Accumbens in Patients with Treatment-Refractory, Chronic, and Severe Anorexia Nervosa: Initial Results at 6 Months of Follow Up

  • Gloria Villalba Martínez,
  • Azucena Justicia,
  • Purificación Salgado,
  • José María Ginés,
  • Rocío Guardiola,
  • Carlos Cedrón,
  • María Polo,
  • Ignacio Delgado-Martínez,
  • Santiago Medrano and
  • Víctor Pérez
  • + 5 authors

22 June 2020

Background: The main objective of this study was to assess the safety and efficacy of deep brain stimulation (DBS) in patients with severe anorexia nervosa (AN). Methods: Eight participants received active DBS to the subcallosal cingulate (SCC) or nu...

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