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  • Feature Paper
  • Article
  • Open Access
13 Citations
5,216 Views
16 Pages

Preparation of Sesquiterpene Lactone Derivatives: Cytotoxic Activity and Selectivity of Action

  • María F. Beer,
  • Augusto E. Bivona,
  • Andrés Sánchez Alberti,
  • Natacha Cerny,
  • Guillermo F. Reta,
  • Víctor S. Martín,
  • José M. Padrón,
  • Emilio L. Malchiodi,
  • Valeria P. Sülsen and
  • Osvaldo J. Donadel

20 March 2019

Cancer is one of the most important causes of death worldwide. Solid tumors represent the great majority of cancers (>90%) and the chemotherapeutic agents used for their treatment are still characterized by variable efficacy and toxicity. Sesquite...