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Search Results (189)

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21 pages, 2585 KiB  
Review
Advances of Articulated Tug–Barge Transport in Enhancing Shipping Efficiency
by Plamen Yanakiev, Yordan Garbatov and Petar Georgiev
J. Mar. Sci. Eng. 2025, 13(8), 1451; https://doi.org/10.3390/jmse13081451 - 29 Jul 2025
Viewed by 198
Abstract
Articulated Tugs and Barges (ATBs) are increasingly recognised for their effectiveness in transporting chemicals, petroleum, bulk goods, and containers, primarily due to their exceptional flexibility and fuel efficiency. Recent projections indicate that the ATB market is on track for significant growth, which is [...] Read more.
Articulated Tugs and Barges (ATBs) are increasingly recognised for their effectiveness in transporting chemicals, petroleum, bulk goods, and containers, primarily due to their exceptional flexibility and fuel efficiency. Recent projections indicate that the ATB market is on track for significant growth, which is expected to lead to an increase in the annual growth rate from 2025 to 2032. This study aims to analyse the current advancements in ATB technology and provide insights into the ATB fleet and the systems that connect tugboats and barges. Furthermore, it highlights the advantages of this transportation system, especially regarding its role in enhancing energy efficiency within the maritime transport sector. Currently, there is limited information available in the public domain about ATBs compared to other commercial vessels. The analysis reveals that much of the required information for modern ATB design is not accessible outside specialised design companies. The study also focuses on conceptual design aspects, which include the main dimensions, articulated connections, propulsion systems, and machinery, concluding with an evaluation of economic viability. Special emphasis is placed on defining the main dimensions, which is a critical part of the complex design process. In this context, the ratios of length to beam (L/B), beam to draft (B/D), beam to depth (B/T), draft to depth (T/D), and power to the number of tugs cubed (Pw/N3) are established as design control parameters in the conceptual design phase. This aspect underscores the novelty of the present study. Additionally, the economic viability is analysed in terms of both CAPEX (capital expenditures) and OPEX (operational expenditures). While CAPEX does not significantly differ between the methods used in different types of commercial ships, OPEX should account for the unique characteristics of ATB vessels. Full article
(This article belongs to the Section Ocean Engineering)
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21 pages, 2201 KiB  
Article
Evaluating China’s Electric Vehicle Adoption with PESTLE: Stakeholder Perspectives on Sustainability and Adoption Barriers
by Daniyal Irfan and Xuan Tang
Sustainability 2025, 17(14), 6258; https://doi.org/10.3390/su17146258 - 8 Jul 2025
Viewed by 547
Abstract
The electric vehicle (EV) business model integrates advanced battery technology, dynamic power train architectures, and intelligent energy management systems with ecosystem strategies and digital services. It incorporates environmental sustainability through lifecycle analysis and renewable energy integration. China, with 9.49 million EV sales in [...] Read more.
The electric vehicle (EV) business model integrates advanced battery technology, dynamic power train architectures, and intelligent energy management systems with ecosystem strategies and digital services. It incorporates environmental sustainability through lifecycle analysis and renewable energy integration. China, with 9.49 million EV sales in 2023 (33% market share), faces infrastructure gaps constraining further growth. China is strategically mitigating CO2 emissions while fostering economic expansion, notwithstanding constraints such as suboptimal battery technology advancements, elevated production expenditure, and enduring ecological impacts. This Political, Economic, Social, Technological, Legal, Environmental (PESTLE) assessment, operationalized through a survey of 800 stakeholders and Statistical Package for the Social Sciences IBM SPSS SPSS (Version 28) quantitative analysis (factor loading = 0.73 for Technology; eigenvalue = 4.12), identifies infrastructure gaps as the dominant barrier (72% of stakeholders). Political factors (β = 0.82) emerged as the strongest adoption predictor, outweighing economic subsidies in significance. The adoption of EVs in China presents a significant prospect for reducing CO2 emissions and advancing technology. However, economic barriers, market dynamics, inadequate infrastructure, regulatory uncertainty, and social acceptance issues are addressed in the assessment. The study recommends prioritizing infrastructure investment (e.g., 500 K fast-charging stations by 2027) and policy stability to overcome adoption barriers. This study provides three key advances: (1) quantification of PESTLE factor weights via factor analysis, revealing technological (infrastructure) and political factors as dominant; (2) identification of infrastructure gaps, not subsidies, as the primary adoption barrier; and (3) demonstration of infrastructure’s persistence post-subsidy cuts. These insights redefine EV adoption priorities in China. Full article
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28 pages, 960 KiB  
Article
Towards Climate-Resilient Agricultural Growth in Nigeria: Can the Current Cash Reserve Ratio Help?
by Amara Priscilia Ozoji, Chika Anastesia Anisiuba, Chinwe Ada Olelewe, Imaobong Judith Nnam, Chidiebere Nnamani, Ngozi Mabel Nwekwo, Arinze Reminus Odoh and Geoffrey Ndubuisi Udefi
Sustainability 2025, 17(13), 6003; https://doi.org/10.3390/su17136003 - 30 Jun 2025
Viewed by 400
Abstract
The ability of the agriculture sector, which is exposed to climate hazards, to cope with climate challenges and to strive in spite of them, is conceptualized as the resilience of agriculture. In enhancing climate-resilient agriculture, the cash reserve ratio (CRR) is generally perceived [...] Read more.
The ability of the agriculture sector, which is exposed to climate hazards, to cope with climate challenges and to strive in spite of them, is conceptualized as the resilience of agriculture. In enhancing climate-resilient agriculture, the cash reserve ratio (CRR) is generally perceived to serve two crucial functions: first, encouraging banks to allocate credit to agriculturalists for climate-resilient agricultural practices; second, enhancing agriculturalists’ ability to sustain agricultural output growth in spite of climate crises. In light of this, we conducted an ex post evaluation of the effect of the currently in-use CRR on bank loans to climate-challenged Nigeria’s agriculture sector for climate-resilient agricultural practices. Additionally, this study investigates the CRR’s impact(s) on agricultural output growth amidst climate challenges. Other additional independent variables include monetary policy rate, government capital expenditures on agriculture, and government recurrent expenditures on agriculture, as well as temperature, precipitation, and the renewable energy supply. Using annual data from 1990 to 2022, the results from an autoregressive, distributed lag approach suggest that the standard CRR stipulated by the Central Bank of Nigeria in the present era of climate change cannot entirely sustain climate-resilient agriculture, evident in the present study’s discoveries on its inability to perform its two major functions (credit and growth) in enhancing agricultural resilience. These findings highlight the need for the green differentiation of the CRR to ensure its effective utilization in enhancing climate resilience. Full article
(This article belongs to the Special Issue Sustainability of Rural Areas and Agriculture under Uncertainties)
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31 pages, 1271 KiB  
Article
Assessment of the Projects’ Prospects in the Economic and Technological Development of the Oil and Gas Complex in the Republic of Mozambique
by Tatyana Semenova and Nunes Churrana
Resources 2025, 14(7), 106; https://doi.org/10.3390/resources14070106 - 28 Jun 2025
Viewed by 1070
Abstract
This study is devoted to a comprehensive technical and economic assessment of the prospects for the development of the oil and gas sector in the Republic of Mozambique in the context of the global energy transition. The analysis of key gas projects, including [...] Read more.
This study is devoted to a comprehensive technical and economic assessment of the prospects for the development of the oil and gas sector in the Republic of Mozambique in the context of the global energy transition. The analysis of key gas projects, including Coral South FLNG and Mozambique LNG, focused on their technological features, economic parameters and environmental impact. It is shown that the introduction of floating liquefaction technology reduces capital expenditures, increases operational flexibility, and minimizes infrastructure risks, especially in conditions of geopolitical instability. Based on a comparative analysis of the projects, it was found that the use of modular solutions and the integration of carbon capture and storage (CCS) systems contribute to improving sustainability and investment attractiveness. A patent analysis of technological innovations was carried out, which made it possible to substantiate the prospects for using nanotechnologies and advanced CO2 capture systems for further development of the sector. The results of the study indicate the need to strengthen content localization, develop human capital, and create effective revenue management mechanisms to ensure sustainable growth. The developed strategic development concept is based on the principles of the sixth technological paradigm, which implies an emphasis on environmental standards and technological modernization, including on the basis of nanotechnology. Thus, it is established that the successful implementation of gas projects in Mozambique can become the basis for long-term socio-economic development of the country, provided that technological and institutional innovations are integrated. Full article
(This article belongs to the Special Issue Assessment and Optimization of Energy Efficiency)
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24 pages, 3890 KiB  
Article
Dietary Insulinogenic Amino Acid Restriction Improves Glucose Metabolism in a Neonatal Piglet Model
by Matthew W. Gorton, Parniyan Goodarzi, Xia Lei, Michael Anderson, Mohammad Habibi, Nedra Wilson and Adel Pezeshki
Nutrients 2025, 17(10), 1675; https://doi.org/10.3390/nu17101675 - 15 May 2025
Viewed by 772
Abstract
Background: Dietary consumption of insulinogenic amino acids (IAA) is known to contribute to the development of insulin resistance. It remains to be studied whether dietary IAA restriction improves glucose metabolism and insulin sensitivity and whether this improvement is related to alterations in glucose [...] Read more.
Background: Dietary consumption of insulinogenic amino acids (IAA) is known to contribute to the development of insulin resistance. It remains to be studied whether dietary IAA restriction improves glucose metabolism and insulin sensitivity and whether this improvement is related to alterations in glucose metabolism in peripheral tissues. The objective of this study was to examine the effect of IAA restriction on glucose metabolism in a piglet model. Methods: Following the acclimation period, thirty-two seven-day-old male piglets were randomly assigned into one of three groups for three weeks as follows (n = 10–11/group): (1) NR (control): basal diet without IAA restriction; (2) R50: basal diet with IAA restricted by 50%; (3) R75: basal diet with IAA restricted by 75%. IAA were alanine (Ala), arginine (Arg), isoleucine (Ile), leucine (Leu), lysine (Lys), threonine (Thr), phenylalanine (Phe), and valine (Val) as suggested by previous studies. Thermal images, body weight, and growth parameters were recorded weekly, oral glucose tolerance tests were performed on week 2 of the study, and blood and tissue samples were collected on week 3 after a meal test. Results: R75 improved glucose tolerance and, together with R50, reduced blood insulin concentration and homeostatic model assessment for insulin resistance (HOMA-IR) value, which is suggestive of improved insulin sensitivity following IAA restriction. R75 increased thermal radiation and decreased adipocyte number in white adipose tissue (WAT). R75 had a greater transcript of glucose transporter 1 (GLUT1), phosphofructokinase, liver type (PFKL), and pyruvate kinase, liver, and RBC (PKLR) in the liver and glucokinase (GCK) in WAT indicating a higher uptake of glucose in the liver and greater glycolysis in both liver and WAT. R75 increased the mRNA abundance of insulin receptor substrate 1 (IRS1) and protein kinase B (AKT1) in skeletal muscle suggestive of enhanced insulin signaling. Further, R75 had a higher mRNA of fibroblast growth factor 21 (FGF-21) in both the liver and hypothalamus and its upstream molecules such as activating transcription factor 4 (ATF4) and inhibin subunit beta E (INHBE) which may contribute to increased energy expenditure and improved glucose tolerance during IAA restriction. Conclusions: IAA restriction improves glucose tolerance and insulin sensitivity in piglets while not reducing body weight, likely through improved hepatic glycolysis and insulin signaling in skeletal muscle, and induced FGF-21 signaling in both the liver and hypothalamus. Full article
(This article belongs to the Section Proteins and Amino Acids)
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16 pages, 744 KiB  
Review
Enhancing Crop Nitrogen Efficiency: The Role of Mixed Nitrate and Ammonium Supply in Plant Growth and Development
by Zhiqi Yang, Huifeng Yan, Haiwei Liu, Lan Yang, Guohua Mi and Peng Wang
Biology 2025, 14(5), 546; https://doi.org/10.3390/biology14050546 - 14 May 2025
Cited by 2 | Viewed by 776
Abstract
Nitrogen fertilizers play a critical role in enhancing crop yields; however, excessive application has resulted in significant environmental challenges, including water contamination and increased greenhouse gas emissions. Therefore, improving nitrogen use efficiency is essential for sustainable agriculture. This review based on a systematic [...] Read more.
Nitrogen fertilizers play a critical role in enhancing crop yields; however, excessive application has resulted in significant environmental challenges, including water contamination and increased greenhouse gas emissions. Therefore, improving nitrogen use efficiency is essential for sustainable agriculture. This review based on a systematic search of Web of Science and CNKI for peer-reviewed studies on maize nitrogen efficiency published between 1945 and 2024 (excluding conference abstracts), this review presents the first multiscale synthesis demonstrating how balanced nitrate–ammonium nutrition coordinates N–C metabolism and phytohormone signaling to boost nitrogen use efficiency and stimulate maize growth, with supporting evidence from other crops. By integrating results from hydroponic and field experiments, the review evaluates the influence of mixed nitrogen sources on nitrogen uptake, root morphology, photosynthesis, carbon metabolism, and hormone signaling. Findings indicate that optimal NO3:NH4+ ratios improve nitrogen absorption through enhanced root development and activation of specific nitrogen transporters. Additionally, mixed nitrogen nutrition increases photosynthetic efficiency, promotes carbon assimilation, reduces energy expenditure, and stimulates auxin-mediated growth. This review shows that balanced nitrate–ammonium co-application synergistically enhances crop nitrogen-use efficiency and yield, provides a theoretical basis for high-efficiency nitrogen-fertilizer development, and helps alleviate environmental pressures, advance sustainable agriculture, and secure food and ecosystem safety. Its efficacy, however, is modulated by soil type, climate, and genotypic variation, necessitating systematic validation and application optimization in future research. Full article
(This article belongs to the Special Issue Plant Nutrition—Molecular Biology and Genetics)
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22 pages, 3034 KiB  
Article
Does Fiscal Decentralization Drive CO2 Emissions? A Quantile Regression Analysis
by Wilman Gustavo Carrillo-Pulgar, Juan Pablo Vallejo-Mata, Katherine Gissel Tixi-Gallegos, Patricio Alejandro Sánchez Cuesta and Josué Romero-Alvarado
J. Risk Financial Manag. 2025, 18(5), 235; https://doi.org/10.3390/jrfm18050235 - 27 Apr 2025
Viewed by 1097
Abstract
Achieving sustainable models is a crucial challenge today, where government actions play a fundamental role. Therefore, this study aims to analyze the impact of fiscal decentralization on CO2 emissions in 40 economies between 2000 and 2020. To this end, an unbalanced panel [...] Read more.
Achieving sustainable models is a crucial challenge today, where government actions play a fundamental role. Therefore, this study aims to analyze the impact of fiscal decentralization on CO2 emissions in 40 economies between 2000 and 2020. To this end, an unbalanced panel was constructed, and the Method of Moments Quantile Regression (MMQR) was employed. As a robustness check, Driscoll and Kraay’s standard errors approach was used. The MMQR results indicate that fiscal decentralization has a positive and significant effect across all quantiles of CO2 emissions. Additionally, it was found that revenue-side decentralization has a greater impact on the lower quantiles of CO2 emissions, while expenditure-side decentralization has a stronger effect on the upper quantiles. The findings also reveal that renewable energy mitigates CO2 emissions, whereas economic growth, resource rents, and information and communication technologies increase them, although the latter with lower statistical significance. These findings are expected to serve as a basis for public policy formulation aimed at improving environmental quality. Full article
(This article belongs to the Section Energy and Environment: Economics, Finance and Policy)
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18 pages, 286 KiB  
Article
Sustainable Development in Focus: CO2 Emissions and Capital Accumulation
by Erdem Oncu, Nil Sirel Ozturk and Ali Erdogan
Sustainability 2025, 17(8), 3513; https://doi.org/10.3390/su17083513 - 14 Apr 2025
Viewed by 457
Abstract
In the modern era, CO2 emissions is a popular and significant study topic. Environmental sustainability is adversely affected by CO2 emissions, which have become the main cause of climate change. Using panel data analysis, this study investigated the connections between CO [...] Read more.
In the modern era, CO2 emissions is a popular and significant study topic. Environmental sustainability is adversely affected by CO2 emissions, which have become the main cause of climate change. Using panel data analysis, this study investigated the connections between CO2 emissions and economic development, capital accumulation, and the use of renewable energy. Long-term connections between variables were examined using the Augmented Mean Group (AMG) and Common Correlated Effects Mean Group (CCEMG) estimators, taking into account heterogeneity and cross-sectional dependence. Additionally, the Dumitrescu–Hurlin Panel Granger Causality Test was used to assess dynamic interactions between variables. Although CH4 emissions increase CO2 emissions, the effects of economic growth and capital accumulation are not statistically significant, as determined using the AMG and CCEMG. Although the use of renewable energy was shown to have the potential to lower CO2 emissions, this impact was not statistically significant. The results of the dynamic panel demonstrate that CO2 emissions increase with capital accumulation. Although methane (CH4) emissions significantly impact CO2 emissions, economic growth, capital accumulation, and renewable energy use do not show statistically significant effects, highlighting the varying influences of these factors across nations. The findings of this study emphasize the need to integrate environmental regulations into capital investment strategies and adopt country-specific policies to effectively reduce CO2 emissions. They also underscore the need to customize green legislation to the specific conditions of each nation while simultaneously advocating for further expenditures in clean energy and the formulation of policies to supplant fossil fuels. Full article
(This article belongs to the Section Economic and Business Aspects of Sustainability)
13 pages, 258 KiB  
Review
Residual Feed Intake as a Behavioral, Nutritional and Economic Criterion in Poultry Production
by Anastasiya Ramankevich, Sofiia Danko, Rafał Banaszkiewicz, Kornel Kasperek and Grzegorz Zięba
Animals 2025, 15(8), 1115; https://doi.org/10.3390/ani15081115 - 12 Apr 2025
Cited by 1 | Viewed by 1640
Abstract
Rising feed costs in the poultry industry have the greatest impact on the price of the final product. To address this issue, several indicators have been developed to assess feed efficiency. One such indicator is residual feed intake (RFI) which represents the difference [...] Read more.
Rising feed costs in the poultry industry have the greatest impact on the price of the final product. To address this issue, several indicators have been developed to assess feed efficiency. One such indicator is residual feed intake (RFI) which represents the difference between actual and expected feed consumption. A lower RFI indicates better performance, making it a valuable trait for sustainable poultry production. RFI is influenced by several factors, including metabolism, body temperature regulation, arrangement of feathers, behavior and physical activity, all of which affect energy expenditure. The trait has moderate heritability, enabling genetic improvement through selective breeding. Accurate calculation of RFI is essential for effective selection, taking into account growth and maintenance needs. Understanding these factors enables breeders to increase feed efficiency, reduce production costs and promote sustainability within the industry. Full article
13 pages, 3264 KiB  
Article
Integrative Utilization of Transcriptomics and Metabolomics Sheds Light on Disparate Growth Performance of Whiteleg Shrimp, Litopenaeus vannamei
by Xin Zhang, Bo Ma, Pengying Li, Ting Chen, Chunhua Ren, Chaoqun Hu and Peng Luo
Int. J. Mol. Sci. 2025, 26(7), 3133; https://doi.org/10.3390/ijms26073133 - 28 Mar 2025
Viewed by 664
Abstract
Litopenaeus vannamei is a key economic species in aquaculture, yet the molecular mechanisms underlying its growth variability remain unclear. This study conducted transcriptomic and metabolomic analyses of fast-growing (NL) and slow-growing (NS) shrimp under identical conditions. A total of 1280 differentially expressed genes [...] Read more.
Litopenaeus vannamei is a key economic species in aquaculture, yet the molecular mechanisms underlying its growth variability remain unclear. This study conducted transcriptomic and metabolomic analyses of fast-growing (NL) and slow-growing (NS) shrimp under identical conditions. A total of 1280 differentially expressed genes (DEGs) related to protein processing, ribosomes, and oxidative phosphorylation, along with 5297 differentially abundant metabolites (DMs) involved in arginine biosynthesis, amino acid metabolism, and pantothenate and CoA biosynthesis, were identified and analyzed. An integrative analysis revealed that the NL shrimp exhibited an enhanced retinol, glutathione, riboflavin, and purine metabolism, which implies a higher tolerance to environmental stress. In contrast, the NS shrimp showed increased fatty acid degradation and an accelerated TCA cycle. This suggests that NS shrimp might require a substantial amount of energy to cope with environmental changes, consequently resulting in increased energy expenditures. This study provides significant insights into the molecular mechanisms underlying the growth disparity in L. vannamei, offering valuable data for future research aimed at optimizing shrimp growth performance and enhancing aquaculture productivity. Full article
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33 pages, 3775 KiB  
Article
Renewable Investments, Environmental Spending, and Emissions in Eastern Europe: A Spatial-Economic Analysis of Management and Policy Decisions Efficiency
by Bogdan Nichifor, Luminita Zait and Ovidiu Turcu
Sustainability 2025, 17(7), 3010; https://doi.org/10.3390/su17073010 - 28 Mar 2025
Cited by 1 | Viewed by 813
Abstract
The transition to a low-carbon economy is a key challenge for Eastern Europe, where economic growth, energy investments, and emission reduction policies interact in complex ways. This study employs a spatial econometric approach to assess the effectiveness of renewable energy investments and government [...] Read more.
The transition to a low-carbon economy is a key challenge for Eastern Europe, where economic growth, energy investments, and emission reduction policies interact in complex ways. This study employs a spatial econometric approach to assess the effectiveness of renewable energy investments and government environmental spending in mitigating CO2 emissions across the region. Using panel data and spatial Durbin models (SDMs), we identify significant spillover effects in emissions reduction, revealing those environmental policies in one country influence neighboring regions. The results indicate that renewable investments have a positive but localized impact on emissions reduction, whereas government environmental expenditure exhibits diminishing returns beyond a threshold of 0.01 GDP. Threshold regression analysis confirms that excessive spending may lead to inefficiencies, reversing its expected benefits. Additionally, stochastic frontier analysis (SFA) highlights disparities in energy efficiency, with some countries demonstrating stronger optimization strategies than others. These findings underscore the importance of policy coordination and targeted investment strategies to enhance the effectiveness of decarbonization efforts. Strengthening regional cooperation and optimizing environmental expenditure allocation can significantly improve sustainability outcomes in Eastern Europe. Full article
(This article belongs to the Special Issue Carbon Neutrality and Green Development)
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17 pages, 995 KiB  
Article
A Pilot Study: Maternal Undernutrition Programs Energy Metabolism and Alters Metabolic Profile and Morphological Characteristics of Skeletal Muscle in Postnatal Beef Cattle
by Daichi Nishino, Taketo Haginouchi, Takeshi Shimogiri, Susumu Muroya, Kenji Kawabata, Saki Urasoko, Ichiro Oshima, Shinobu Yasuo and Takafumi Gotoh
Metabolites 2025, 15(3), 209; https://doi.org/10.3390/metabo15030209 - 19 Mar 2025
Cited by 1 | Viewed by 749
Abstract
Objectives: This study investigated the long-term effects of maternal undernutrition on overall muscle metabolism, growth performance, and muscle characteristics in postnatal offspring of Wagyu (Japanese Black) cattle. Methods: Wagyu cows were divided into nutrient-adequate (control, CNT; n = 4, 120% of [...] Read more.
Objectives: This study investigated the long-term effects of maternal undernutrition on overall muscle metabolism, growth performance, and muscle characteristics in postnatal offspring of Wagyu (Japanese Black) cattle. Methods: Wagyu cows were divided into nutrient-adequate (control, CNT; n = 4, 120% of requirements) and nutrient-restricted groups (NR; n = 4; 60% of requirements), and treated from day 35 of gestation until parturition. Diets were delivered on the basis of crude protein requirements, meeting 100% and 80% of dry matter requirements in CNT and NR groups, respectively. All offspring were provided with the same diet from birth to 300 days of age (d). Longissimus thoracis muscle (LM) samples were collected from the postnatal offspring. Results: The NR offspring had lower birth body weight, but their body weight caught up before weaning. These offspring showed enhanced efficiency in nutrient utilization during the post-weaning growth period. Comprehensive analyses of metabolites and transcripts revealed the accumulation of proteinogenic amino acid, asparagine, in NR offspring LM at 300 d, while the abundance of nicotinamide adenine dinucleotide (NADH) and succinate were reduced. These changes were accompanied by decreased gene expression of nicotinamide phosphoribosyltransferase (NAMPT), NADH: ubiquinone oxidoreductase subunit A12 (NDUFA12), and NADH dehydrogenase subunit 5 (ND5), which are essential for mitochondrial energy production. Additionally, NR offspring LM exhibited decreased abundance of neurotransmitter, along with a higher proportion of slow-oxidative myofibers and a lower proportion of fast-oxidative myofibers at 300 d. Conclusions: Offspring from nutrient-restricted cows might suppress muscle energy production, primarily in the mitochondria, and conserve energy expenditure for muscle protein synthesis. These findings suggest that maternal undernutrition programs a thrifty metabolism in offspring muscle, with long-term effects. Full article
(This article belongs to the Special Issue Unlocking the Mysteries of Muscle Metabolism in the Animal Sciences)
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17 pages, 885 KiB  
Review
Phenotype Assessment and Putative Mechanisms of Ammonium Toxicity to Plants
by Lin-Bei Xie, Li-Na Sun, Zhong-Wei Zhang, Yang-Er Chen, Ming Yuan and Shu Yuan
Int. J. Mol. Sci. 2025, 26(6), 2606; https://doi.org/10.3390/ijms26062606 - 13 Mar 2025
Cited by 1 | Viewed by 777
Abstract
Ammonium (NH4+) and nitrate (NO3) are the primary inorganic nitrogen (N) sources that exert influence on plant growth and development. Nevertheless, when NH4+ constitutes the sole or dominant N source, it can inhibit plant growth, [...] Read more.
Ammonium (NH4+) and nitrate (NO3) are the primary inorganic nitrogen (N) sources that exert influence on plant growth and development. Nevertheless, when NH4+ constitutes the sole or dominant N source, it can inhibit plant growth, a process also known as ammonium toxicity. Over multiple decades, researchers have shown increasing interest in the primary causes, mechanisms, and detoxification strategies of ammonium toxicity. Despite this progress, the current investigations into the mechanisms of ammonium toxicity remain equivocal. This review initially presents a comprehensive assessment of phenotypes induced by ammonium toxicity. Additionally, this review also recapitulates the existing mechanisms of ammonium toxicity, such as ion imbalance, disruption of the phytohormones homeostasis, ROS (reactive oxygen species) burst, energy expenditure, and rhizosphere acidification. We conclude that alterations in carbon–nitrogen (C-N) metabolism induced by high NH4+ may be one of the main reasons for ammonium toxicity and that SnRK1 (Sucrose non-fermenting 1-related kinase) might be involved in this process. The insights proffered in this review will facilitate the exploration of NH4+ tolerance mechanisms and the development of NH4+-tolerant crops in agricultural industries. Full article
(This article belongs to the Special Issue Plant Physiology and Molecular Nutrition)
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21 pages, 3386 KiB  
Article
Assessment of Socio-Economic and Environmental Impacts of Energy Efficiency Improvements in Multi-Apartment Buildings: Case Study of Lithuania
by Rimantė Balsiūnaitė, Viktorija Bobinaitė, Inga Konstantinavičiūtė and Vidas Lekavičius
Sustainability 2025, 17(3), 957; https://doi.org/10.3390/su17030957 - 24 Jan 2025
Viewed by 1120
Abstract
This research aims to assess the socio-economic and environmental impacts of the Lithuanian long-term renovation strategy, focusing on improvements in the energy performance of renovated multi-apartment buildings in the country. The methodology used in the study is centred on the CleanProd general equilibrium [...] Read more.
This research aims to assess the socio-economic and environmental impacts of the Lithuanian long-term renovation strategy, focusing on improvements in the energy performance of renovated multi-apartment buildings in the country. The methodology used in the study is centred on the CleanProd general equilibrium model, which is based on publicly available data from the FIGARO database and Eurostat’s non-financial transaction statistics. The four renovation financing scenarios analysed are represented in the model by changes in the demand for energy resources and construction and other transactions related to the renovation programme. To reflect the dynamic nature of the renovation programme, counterfactual equilibria are sought for each year of the renovation programme. The results revealed that renovation of multi-apartment buildings brings net benefits, including long-term increases in gross domestic products (GDPs) and employment, as well as a decrease in economy-wide greenhouse gas (GHG) emissions, and is aligned with the binding European Union’s energy efficiency target to reduce energy consumption at least by 11.7% in 2030 (in comparison to 2020). The Increase in Taxes on Products scenario is modelled as the most favourable scenario. It assures annual GDP growth by 0.37%, employment growth by 2170 jobs a year, including 606 jobs for young people, and an annual decrease in GHG emissions by 929–1043 ktCO2eq. It is found that the most considerable benefits are received during the renovation of medium-size buildings when construction demand increases by EUR 600,000–800,000 per year and natural gas and district heating demand are reduced by EUR 59,000–187,000 per year. Other scenarios demonstrating different building renovation and energy efficiency support practices, including Costless, Reallocation of Governmental Expenditure, and Governmental Loan, show relevant but slightly lower benefits. Full article
(This article belongs to the Section Energy Sustainability)
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9 pages, 595 KiB  
Article
The Epigenetic Machinery and Energy Expenditure: A Network to Be Revealed
by Elisabetta Prada, Giulia Bruna Marchetti, Denise Pires Marafon, Alessandra Mazzocchi, Giulietta Scuvera, Lidia Pezzani, Carlo Agostoni and Donatella Milani
Genes 2025, 16(1), 104; https://doi.org/10.3390/genes16010104 - 19 Jan 2025
Viewed by 1093
Abstract
Mendelian disorders of the epigenetic machinery (MDEMs) include a large number of conditions caused by defective activity of a member of the epigenetic machinery. MDEMs are characterized by multiple congenital abnormalities, intellectual disability and abnormal growth. that can be variably up- or down-regulated. [...] Read more.
Mendelian disorders of the epigenetic machinery (MDEMs) include a large number of conditions caused by defective activity of a member of the epigenetic machinery. MDEMs are characterized by multiple congenital abnormalities, intellectual disability and abnormal growth. that can be variably up- or down-regulated. Background/Objectives: In several MDEMs, a predisposition to metabolic syndrome and obesity since childhood has been reported. Methods: To investigate the metabolic bases of this abnormal growth, we collected physical data from a heterogeneous pool of 38 patients affected by MDEMs. Thirty-five patients performed indirect calorimetry (as a measure of resting energy expenditure, REE) and blood tests to monitor plasmatic nutritional parameters. Conclusions: Although limited by a small-sized and heterogeneous sample, our study demonstrates a linear correlation between REE and physical parameters, OFC, height and weight, and observed a slight imbalance on several plasmatic spies of metabolic syndrome predisposition. Furthermore, we demonstrated a significantly higher REE in Sotos Syndrome type 1 patients compared to the controls, which resulted independent from height, suggesting that impaired metabolism in these patients may go beyond overgrowth. Full article
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