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  • Case Report
  • Open Access
3 Citations
4,840 Views
9 Pages

23 December 2021

A 7-year-old castrated male Labrador retriever was referred for evaluation of progressive hind limb paresis of 4 weeks’ duration. On computed tomography and magnetic resonance imaging examination, masses were found in several regions including the lu...

  • Case Report
  • Open Access
2,829 Views
9 Pages

Thoracic Extradural Psammomatous Meningioma on T6–T8: A Case Report and Literature Review

  • Roberto Renan Albavera-Gutiérrez,
  • Arturo Espíndola-Rodríguez,
  • Carlos Alberto Castro-Fuentes,
  • Ana Karen Aguayo Martínez,
  • Omar Esteban Valencia-Ledezma,
  • Juan Manuel Salgado-Camacho,
  • Luis Bernal Mendoza and
  • Ernesto Nuñez Nava

1 October 2024

Tumors of the spine are rare, with an incidence of 1.0 and 1.5 per 100,000 individuals. A 44-year-old female patient underwent emergency surgery for posterior decompression and tumor resection. A 3-level laminectomy was performed from T6 to T8 using...

  • Article
  • Open Access
5 Citations
2,815 Views
14 Pages

Extradural Primary Malignant Spinal Tumors in a Population Younger than 25 Years: An Ambispective International Multicenter Study on Onco-Surgical Outcomes

  • Alexander C. Disch,
  • Stefano Boriani,
  • Alessandro Luzzati,
  • Laurence D. Rhines,
  • Charles G. Fisher,
  • Aron Lazary,
  • Ziya L. Gokaslan,
  • Dean Chou,
  • Michelle J. Clarke and
  • The AO Spine Knowledge Forum Tumor
  • + 4 authors

30 January 2023

Extradural malignant primary spinal tumors are rare and outcome data, especially for younger patients, is limited. In a worldwide (11 centers) study (Predictors of Mortality and Morbidity in the Surgical Management of Primary Tumors of the Spine stud...

  • Article
  • Open Access
815 Views
15 Pages

20 October 2025

Background/Objectives: The anterior communicating artery (AcomA) is one of the most common sites of intracranial aneurysms. We aimed to investigate the effect of routine extradural anterior clinoidectomy (EAC) and extradural lamina terminalis fenestr...

  • Case Report
  • Open Access
944 Views
9 Pages

13 August 2025

Continuous extradural infusions (CEIs) provide sustained analgesia, avoiding fluctuations seen with bolus administrations. An extradural catheter was placed in a cat with severe abdominal trauma following a vehicular accident. To provide sustained pa...

  • Case Report
  • Open Access
6 Citations
6,500 Views
10 Pages

2 December 2021

A 23-year-old woman was presented to the Emergency Unit with intracranial hypertension syndrome and blindness in her left eye which had started recently. A cranial native computed tomography scan and a magnetic resonance imaging (MRI) with contrast e...

  • Article
  • Open Access
5 Citations
2,692 Views
9 Pages

Extradural Clinoidectomy in Clinoidal Meningiomas: Analysis of the Surgical Technique and Evaluation of the Clinical Outcome

  • Luigi Sampirisi,
  • Luca D’Angelo,
  • Mauro Palmieri,
  • Alessandro Pesce and
  • Antonio Santoro

23 September 2022

The surgical treatment of clinoidal meningiomas is currently still discussed in the literature. Different surgical approaches have been proposed and evaluated, in multiple studies, in order to improve the surgical outcomes. The aim of this study is t...

  • Systematic Review
  • Open Access
3 Citations
2,200 Views
15 Pages

Primary Extradural Meningioma: A Systematic Review of Diagnostic Features, Clinical Management, and Surgical Outcomes

  • Kishore Balasubramanian,
  • Jeffrey A. Zuccato,
  • Abdurrahman F. Kharbat,
  • Christopher Janssen,
  • Nancy M. Gonzalez and
  • Ian F. Dunn

22 November 2024

Objective: This systematic review consolidates the literature on primary extradural meningiomas (PEMs), a rare subset of meningiomas. We describe the clinical features, management strategies used, and treatment outcomes for published cases. Methods:...

  • Article
  • Open Access
8 Citations
2,887 Views
12 Pages

Extradural Motor Cortex Stimulation in Parkinson’s Disease: Long-Term Clinical Outcome

  • Carla Piano,
  • Francesco Bove,
  • Delia Mulas,
  • Enrico Di Stasio,
  • Alfonso Fasano,
  • Anna Rita Bentivoglio,
  • Antonio Daniele,
  • Beatrice Cioni,
  • Paolo Calabresi and
  • Tommaso Tufo

Previous investigations have reported on the motor benefits and safety of chronic extradural motor cortex stimulation (EMCS) for patients with Parkinson’s disease (PD), but studies addressing the long-term clinical outcome are still lacking. In this...

  • Article
  • Open Access
2 Citations
2,940 Views
13 Pages

Outcomes of Surgical Treatment for Extradural Benign Primary Spinal Tumors in Patients Younger than 25 Years: An Ambispective International Multicenter Study

  • Alexander C. Disch,
  • Stefano Boriani,
  • Aron Lazary,
  • Laurence D. Rhines,
  • Alessandro Luzzati,
  • Ziya L. Gokaslan,
  • Charles G. Fisher,
  • Michael G. Fehlings,
  • Michelle J. Clarke and
  • The AO Spine Knowledge Forum Tumor
  • + 4 authors

20 January 2023

Extradural primary spinal tumors were retrospectively analyzed from a prospective database of 1495 cases. All subjects with benign primary tumors under the age of 25 years, who were enrolled between 1990 and 2012 (Median FU was 2.4 years), were ident...

  • Article
  • Open Access
9 Citations
5,391 Views
13 Pages

Surgical Management of Pre-Chiasmatic Intraorbital Optic Nerve Gliomas in Children after Loss of Visual Function—Resection from Bulbus to Chiasm

  • Julian Zipfel,
  • Jonas Tellermann,
  • Dorothea Besch,
  • Eckart Bertelmann,
  • Martin Ebinger,
  • Pablo Hernáiz Driever,
  • Jens Schittenhelm,
  • Rudi Beschorner,
  • Arend Koch and
  • Martin Ulrich Schuhmann
  • + 1 author

24 March 2022

Optic pathway gliomas in children carry significant morbidity and therapeutic challenges. For the subgroup of pre-chiasmatic gliomas, intraorbital and intradural resection is a curative option after blindness. We present a two-center cohort using dif...

  • Article
  • Open Access
3 Citations
5,342 Views
9 Pages

Selective Vestibular Neurectomy through the Presigmoid Retrolabyrinthine Approach in the Treatment of Meniere’s Disease

  • Fabrizio Salvinelli,
  • Francesca Bonifacio,
  • Mara Capece,
  • Denis Aiudi,
  • Alessio Iacoangeli,
  • Fabio Greco,
  • Maurizio Gladi and
  • Maurizio Iacoangeli

Background: Meniere’s disease (MD) is a disabling disease, especially in patients who are refractory to medical therapy. Moreover, selective vestibular neurectomy (VN), in these selected cases, can be considered a surgical alternative which pre...

  • Case Report
  • Open Access
4 Citations
5,341 Views
8 Pages

A Combination of Magnetic Resonance Imaging Techniques to Localize the Dural Defect in a Case of Superficial Siderosis—A Case Report

  • Hiroyuki Katoh,
  • Shuhei Shibukawa,
  • Keiko Yamaguchi,
  • Akihiko Hiyama,
  • Tomohiko Horie,
  • Masato Sato and
  • Masahiko Watanabe

Background: Superficial siderosis is a progressively disabling disease caused by recurrent subarachnoid hemorrhage with accumulation of hemosiderin in the surface of the central nervous system. Although a wide variety of conditions may cause superfic...

  • Article
  • Open Access
1 Citations
2,471 Views
12 Pages

Shoulder Traction as a Possible Risk Factor for C5 Palsy in Anterior Cervical Surgery: A Cadaveric Study

  • Ja-Yeong Yoon,
  • Sung-Min Kim,
  • Seong-Hwan Moon,
  • Hak-Sun Kim,
  • Kyung-Soo Suk,
  • Si-Young Park,
  • Ji-Won Kwon and
  • Byung-Ho Lee

1 September 2024

Background and Objectives: Many risk factors for postoperative C5 palsy (PC5P) have been reported regarding a “cord shift” after a posterior approach. However, there are few reports about shoulder traction as a possible risk factor of ant...

  • Article
  • Open Access
5 Citations
3,631 Views
14 Pages

Extremely Rare Pathologies of the Craniovertebral Junction Region: A Case Series and Review of the Literature

  • Eugenia Maiorano,
  • Giannantonio Spena,
  • Fabio Sovardi,
  • Puya Dehgani-Mobaraki,
  • Fabio Pagella,
  • Andrea Montalbetti,
  • Elisabetta Peppucci,
  • Christian Grasso and
  • Cesare Zoia

28 August 2023

Background: The craniovertebral junction is a complex region, connecting the occiput, the atlas, the axis, and the containing vital neural and vascular structures. There is a great variability in diseases involving the craniovertebral junction, of di...

  • Article
  • Open Access
3 Citations
3,225 Views
13 Pages

A Prevalence Anatomic-Imaging Study of the Posterior Inferior Cerebellar Artery’s Origin

  • Ana-Maria Davidoiu,
  • Mugurel Constantin Rusu,
  • Corneliu Toader and
  • Petrinel Mugurel Rădoi

26 August 2024

Background and Objectives: Typically, the vertebral arteries (VAs) enter the posterior fossa through dural rings and further unite, forming the basilar artery. The posterior inferior cerebellar artery (PICA) is usually a branch of the V4 segment of t...

  • Case Report
  • Open Access
1 Citations
3,256 Views
14 Pages

Given the complex and multifaceted nature of resecting giant tumors in the anterior, middle, and, to a lesser extent, the posterior fossa, we present two example strategies for navigating the intricacies of such tumors. The foundational premise of th...

  • Article
  • Open Access
7 Citations
3,387 Views
11 Pages

9 January 2023

Minimization of the surgical approaches to spinal extradural metastases resection and stabilization was advocated by the 2012 Oncological Guidelines for Spinal Metastases Management. Minimally invasive approaches to spine oncology surgery (MISS) are...

  • Case Report
  • Open Access
1,536 Views
20 Pages

Twice the Leak: Managing CSF Fistulas in a Recurrent Thoracic Arachnoid Cyst—A Case Report

  • Federica Bellino,
  • Leonardo Bradaschia,
  • Marco Ajello and
  • Diego Garbossa

21 August 2025

Background and Clinical Significance: Spinal arachnoid cysts are rare lesions that may become symptomatic through progressive spinal cord compression. We present a complex case of a thoracic extradural SAC in a 17-year-old male, managed through a ste...

  • Case Report
  • Open Access
2,569 Views
8 Pages

Cervical Disc Extrusion with Dorsal Migration in a Pet Rabbit

  • Laura Porcarelli,
  • Elena Dell’Era,
  • Tommaso Collarile,
  • Valeria De Palma,
  • Noemi Morara,
  • Kaspar Matiasek and
  • Daniele Corlazzoli

21 July 2024

An 8-year-old rabbit presented with a 5-day history of acute difficulty in walking. Neurological examination revealed tetraparesis, proprioceptive deficits in both pelvic limbs and the right thoracic limb, decreased withdrawal reflex on the right tho...

  • Article
  • Open Access
6 Citations
3,050 Views
14 Pages

Delayed Postoperative Hyponatremia Following Endoscopic Transsphenoidal Surgery for Non-Adenomatous Parasellar Tumors

  • Hirotaka Hasegawa,
  • Masahiro Shin,
  • Noriko Makita,
  • Yuki Shinya,
  • Kenji Kondo and
  • Nobuhito Saito

20 December 2020

Little is known about delayed postoperative hyponatremia (DPH) accompanied with transsphenoidal surgery for non-adenomatous skull base tumors (NASBTs). Consecutive data on 30 patients with parasellar NASBT was retrospectively reviewed with detailed a...

  • Article
  • Open Access
7 Citations
6,417 Views
17 Pages

Reoperation in Chiari-1 Malformations

  • Giuseppe Talamonti,
  • Marco Picano,
  • Maria Fragale,
  • Eleonora Marcati,
  • Giulia Meccariello,
  • Davide Boeris and
  • Marco Cenzato

13 April 2023

(1) Background: The issue of unsuccessful surgery for Chiari-1 malformation (CM-1), as well as its potential causes and possible solutions, remains poorly documented and studied. (2) Methods: From a retrospective review of a personal series of 98 pat...

  • Case Report
  • Open Access
319 Views
10 Pages

13 February 2026

Background and Clinical Significance: We report a rare case of a 66-year-old male with malignant non-germinal center-type large B-cell lymphoma involving the thoracic epidural, cauda equina, and filum terminal simultaneously. Case Presentation: The p...

  • Article
  • Open Access
3 Citations
2,546 Views
14 Pages

19 July 2024

Objective: Intradural spinal metastases are considered rare. At present, limited information is available on incidence, surgical management, and outcomes. Methods: We conducted a retrospective patient chart review from 2002 to 2024, identifying all p...

  • Case Report
  • Open Access
1,905 Views
8 Pages

3 September 2024

Electrical burn injuries to the scalp are at risk of extensive tissue damage and neurological complications. We present the case of a patient who came into contact with a high-voltage power line while cherry picking, resulting in a large full-thickne...

  • Review
  • Open Access
18 Citations
15,152 Views
25 Pages

Intradural Pediatric Spinal Tumors: An Overview from Imaging to Novel Molecular Findings

  • Antonio Marrazzo,
  • Antonella Cacchione,
  • Sabrina Rossi,
  • Alessia Carboni,
  • Carlo Gandolfo,
  • Andrea Carai,
  • Angela Mastronuzzi and
  • Giovanna Stefania Colafati

18 September 2021

Pediatric spinal tumors are rare and account for 10% of all central nervous system tumors in children. Onset usually occurs with chronic nonspecific symptoms and may depend on the intra- or extradural neoplastic location. Meningiomas, schwannomas, an...

  • Article
  • Open Access

Surgical Management of Juvenile Nasopharyngeal Angiofibroma Using Lateral Rhinotomy: Study of 80 Cases

  • Ninad Gaikwad,
  • Nilam Sathe,
  • Abhijeet Bhatia,
  • Dhanashree Chiplunkar and
  • Manoj Patil

16 December 2011

A series of 80 patients with histopathologically confirmed juvenile nasopharyngeal angiofibroma were treated surgically over a period of ten years (1995–2004). The lateral rhinotomy approach was used to expose the tumor and its extensions. Lateral rh...

  • Article
  • Open Access
1 Citations
3,063 Views
21 Pages

Clinical Features, MRI Findings, Treatment, and Outcomes in Dogs with Haemorrhagic Myelopathy Secondary to Steroid-Responsive Meningitis-Arteritis: Nine Cases (2017–2024)

  • Giuseppe Vitello,
  • Beatrice Enrica Carletti,
  • Sergio A. Gomes,
  • Luca Motta,
  • Alessia Colverde,
  • Andrea Holmes and
  • Massimo Mariscoli

This retrospective multicentre study investigated haemorrhagic myelopathy as a rare complication of steroid-responsive meningitis-arteritis (SRMA) in nine dogs. The affected dogs exhibited varied neurological deficits, including cervical hyperesthesi...

  • Feature Paper
  • Article
  • Open Access
26 Citations
5,515 Views
24 Pages

Neuroprotection, Recovery of Function and Endogenous Neurogenesis in Traumatic Spinal Cord Injury Following Transplantation of Activated Adipose Tissue

  • Stephana Carelli,
  • Toniella Giallongo,
  • Federica Rey,
  • Mattia Colli,
  • Delfina Tosi,
  • Gaetano Bulfamante,
  • Anna Maria Di Giulio and
  • Alfredo Gorio

8 April 2019

Spinal cord injury (SCI) is a devastating disease, which leads to paralysis and is associated to substantially high costs for the individual and society. At present, no effective therapies are available. Here, the use of mechanically-activated lipoas...

  • Article
  • Open Access
619 Views
25 Pages

19 December 2025

Objectives: Atypical teratoid/rhabdoid tumors (ATRTs) are rare, malignant central nervous system (CNS) neoplasms that predominantly affect infants and young children. While ATRT arises throughout the CNS, its extracranial counterpart, malignant rhabd...

  • Article
  • Open Access
15 Citations
6,714 Views
14 Pages

A New Concept of Sustainable Wind Turbine Blades: Bio-Inspired Design with Engineered Adhesives

  • Leon Mishnaevsky,
  • Mohsen Jafarpour,
  • Johanna Krüger and
  • Stanislav N. Gorb

22 September 2023

In this paper, a new concept of extra-durable and sustainable wind turbine blades is presented. The two critical materials science challenges of the development of wind energy now are the necessity to prevent the degradation of wind turbine blades fo...

  • Case Report
  • Open Access
1 Citations
2,387 Views
7 Pages

3 November 2022

Schwannomatosis is characterized by the presence of multiple schwannomas without landmarks of NF2. It is considered the rarest form of neurofibromatosis (NF). Here, we report the first case of familial schwannomatosis with regard to the segmental/gen...

  • Case Report
  • Open Access
1 Citations
4,455 Views
7 Pages

Surgical Treatment of Cavernous Sinus Cavernomas: Evidence from Vietnam

  • Duc-Anh Nguyen,
  • Hao The Nguyen,
  • Thang Van Duong,
  • Binh Hoa Pham and
  • Hoang-Long Vo

Cavernous sinus cavernomas, a rare vascular malformation, represents 3% of all benign cavernous sinus tumors. Both clinical and radiological signs are important for differentiating this condition from other cavernous sinus diseases. The best treatmen...

  • Article
  • Open Access
6 Citations
3,760 Views
12 Pages

Compromised Cranio-Spinal Suspension in Chiari Malformation Type 1: A Potential Role as Secondary Pathophysiology

  • Belinda Shao,
  • Jonathan A. Poggi,
  • Natalie Amaral-Nieves,
  • Daniel Wojcik,
  • Kevin L. Ma,
  • Owen P. Leary and
  • Petra M. Klinge

15 December 2022

In Chiari Malformation Type I (CM1), low-lying tonsils obstruct the cisterna magna at the foramen magnum, thereby compromising the essential juncture between the cranial and spinal compartments. The anatomical obstruction of the cisterna magna inhibi...

  • Article
  • Open Access
19 Citations
4,570 Views
5 Pages

Surgical Approach for Spinal Tumors: Our Experience in Combined Military Hospital Dhaka

  • Md Aminul Islam,
  • Maj Shamantha Afreen,
  • Nicola Montemurro and
  • Bipin Chaurasia

12 August 2021

(1) Background: spinal tumors not only causes structural problem but also it affects body functionality, too. Surgery has a key role in management of patients with spinal tumor. The aim of this study is that to observe their clinical profile, functio...

  • Case Report
  • Open Access
1 Citations
3,681 Views
11 Pages

29 March 2023

We present a case of occipital lobe meningioma resection in an elderly cat. The surgery was performed with the goal of avoiding major bleeding. An 11-year-old castrated indoor-only male Persian Chinchilla (5.5 kg) was presented with a month-long hist...

  • Article
  • Open Access
1 Citations
2,474 Views
12 Pages

Clinical and Pathological Profiles of Vertebral Bone Metastases from Endometrial Cancers: Evidence from a Twenty-Year Case Series

  • Stefano Bandiera,
  • Francesca Salamanna,
  • Veronica Borsari,
  • Deyanira Contartese,
  • Marco Bontempi,
  • Matilde Tschon,
  • Giovanni Tosini,
  • Stefano Pasini,
  • Silvia Terzi and
  • Alessandro Gasbarrini
  • + 1 author

25 November 2022

Patients with endometrial cancer (EC) frequently have metastases to lungs, extra-pelvic nodes, and liver. Although an uncommon occurrence, cases of EC metastasis to bone, prevalently in vertebral bone, have also been reported. The objective of this s...

  • Article
  • Open Access
8 Citations
6,778 Views
22 Pages

Neuropathology of Central and Peripheral Nervous System Lymphoma in Dogs and Cats: A Study of 92 Cases and Review of the Literature

  • Niccolò Fonti,
  • Francesca Parisi,
  • Çağla Aytaş,
  • Sara Degl’Innocenti and
  • Carlo Cantile

27 February 2023

The literature about nervous system lymphoma (NSL) in dogs and cats is fragmentary, based on a few case series and case reports with heterogeneous results. The aim of our study was to retrospectively analyze 45 cases of canine and 47 cases of feline...

  • Article
  • Open Access
8 Citations
3,188 Views
14 Pages

LRRK2 Inhibition by PF06447475 Antagonist Modulates Early Neuronal Damage after Spinal Cord Trauma

  • Alessia Filippone,
  • Deborah Mannino,
  • Laura Cucinotta,
  • Irene Paterniti,
  • Emanuela Esposito and
  • Michela Campolo

23 August 2022

Spinal cord injury (SCI) is a devastating event followed by neurodegeneration, activation of the inflammatory cascade, and immune system. The leucine-rich-repeat kinase 2 (LRRK2) is a gene associated with Parkinson’s disease (PD), moreover, its...

  • Review
  • Open Access
34 Citations
14,108 Views
26 Pages

Multidisciplinary Approach to Spinal Metastases and Metastatic Spinal Cord Compression—A New Integrative Flowchart for Patient Management

  • Miguel Esperança-Martins,
  • Diogo Roque,
  • Tiago Barroso,
  • André Abrunhosa-Branquinho,
  • Diogo Belo,
  • Nuno Simas and
  • Luis Costa

16 March 2023

Metastatic spine disease (MSD) and metastatic spinal cord compression (MSCC) are major causes of permanent neurological damage and long-term disability for cancer patients. The development of MSD is pathophysiologically framed by a cooperative intera...

  • Systematic Review
  • Open Access
16 Citations
3,981 Views
11 Pages

A Systematic Review of Intracranial Complications in Adults with Pott Puffy Tumor over Four Decades

  • Giorgos Sideris,
  • Efstathia Davoutis,
  • Evangelos Panagoulis,
  • Pavlos Maragkoudakis,
  • Thomas Nikolopoulos and
  • Alexander Delides

The purpose of this study is to investigate the risk factors of intracranial complications in adult patients with Pott Puffy Tumor (PPT). A systematic review was conducted of clinical studies from January 1983 to December 2022 that reported on PPT ad...

  • Article
  • Open Access
13 Citations
4,875 Views
22 Pages

Surgical Anatomy of the Microscopic and Endoscopic Transorbital Approach to the Middle Fossa and Cavernous Sinus: Anatomo-Radiological Study with Clinical Applications

  • Simona Serioli,
  • Mariagrazia Nizzola,
  • Pedro Plou,
  • Alessandro De Bonis,
  • Jenna Meyer,
  • Luciano C. P. C. Leonel,
  • Andrea A. Tooley,
  • Lilly H. Wagner,
  • Elizabeth A. Bradley and
  • Maria Peris-Celda
  • + 3 authors

6 September 2023

Background: The transorbital approaches (TOAs) have acquired growing notoriety, thanks to their ability to offer alternative corridors to the skull base. However, the limited access and the unfamiliarity with this surgical perspective make recognitio...

  • Case Report
  • Open Access
4 Citations
5,435 Views
9 Pages

Successful Treatment of Vertebral Osteosarcoma in a Cat Using Marginal Surgical Excision and Chemotherapy

  • Antonio Giuliano,
  • Virginie De Busscher,
  • Diane D. A. Lu,
  • Karen W. L. Ng and
  • Julia A. Beatty

23 June 2022

A three-year-old male neutered Norwegian Forest cat was referred for bilateral ambulatory paraparesis and spinal pain. On magnetic resonance imaging (MRI), a mass involving the right epaxial muscles with vertebral canal invasion and causing marked ex...

  • Article
  • Open Access
5 Citations
4,804 Views
17 Pages

Surgical Antimicrobial Prophylaxis in Neonates and Children Undergoing Neurosurgery: A RAND/UCLA Appropriateness Method Consensus Study

  • Susanna Esposito,
  • Mino Zucchelli,
  • Sonia Bianchini,
  • Laura Nicoletti,
  • Sara Monaco,
  • Erika Rigotti,
  • Laura Venditto,
  • Cinzia Auriti,
  • Caterina Caminiti and
  • on behalf of the Peri-Operative Prophylaxis in Neonatal and Paediatric Age (POP-NeoPed) Study Group
  • + 20 authors

Pediatric neurosurgery is a highly specialized branch of surgery in which surgical site infections (SSIs) are potentially serious complications that can also adversely affect a good surgical outcome, compromising functional recovery and, in some case...

  • Article
  • Open Access
1 Citations
3,074 Views
14 Pages

5 November 2022

Dysregulation of high-frequency neuronal oscillations has been implicated in the pathophysiology of schizophrenia. Chronic methamphetamine (METH) use can induce psychosis similar to paranoid schizophrenia. The current study in mice aimed to determine...

  • Systematic Review
  • Open Access
5 Citations
4,320 Views
11 Pages

27 February 2023

The purpose of this systematic review was to analyze evidence based on existing studies on the ability of initial CT imaging to predict mortality in severe traumatic brain injuries (TBIs) in pediatric patients. An experienced librarian searched for a...

  • Review
  • Open Access
32 Citations
5,358 Views
17 Pages

The Transorbital Approach: A Comprehensive Review of Targets, Surgical Techniques, and Multiportal Variants

  • Matteo De Simone,
  • Cesare Zoia,
  • Anis Choucha,
  • Doo-Sik Kong and
  • Lucio De Maria

The transorbital approach (TOA) is gaining popularity in skull base surgery scenarios. This approach represents a valuable surgical corridor to access various compartments and safely address several intracranial pathologies, both intradurally and ext...

  • Communication
  • Open Access
1 Citations
5,596 Views
9 Pages

The Extended-Sphenoid Ridge Approach: A New Technique for the Surgical Treatment of Skull Base Tumors in Pediatric Patients

  • Roberto Garcia-Navarrete,
  • Alfonso Marhx-Bracho,
  • Javier Terrazo-Lluch and
  • José Luis Pérez-Gómez

The sphenoid ridge approach (SRA) was initially described as a surgical technique for treating vascular pathologies near the Sylvian fissure. However, limited studies have systematically explored the use of skull base techniques in pediatric patients...

  • Systematic Review
  • Open Access
19 Citations
4,099 Views
14 Pages

Surgical Management of Craniovertebral Junction Schwannomas: A Systematic Review

  • Paolo Palmisciano,
  • Gianluca Ferini,
  • Gina Watanabe,
  • Andie Conching,
  • Christian Ogasawara,
  • Gianluca Scalia,
  • Othman Bin-Alamer,
  • Ali S. Haider,
  • Maurizio Passanisi and
  • Giuseppe E. Umana
  • + 6 authors

9 July 2022

Background: Craniovertebral junction (CVJ) schwannomas are rare, with surgery and stereotactic radiosurgery (SRS) being effective yet challenging options. We systematically reviewed the literature on CVJ schwannomas. Methods: PubMed, Scopus, Web-of-S...

  • Case Report
  • Open Access
1,544 Views
20 Pages

27 August 2025

Solitary fibrous tumors (SFTs) of the spine are rare. SFTs, especially those classified as WHO grade II or III (previously termed hemangiopericytomas), are aggressive neoplasms with a high recurrence rate and metastatic potential. In the literature,...

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