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Search Results (961)

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Keywords = ethical culture

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24 pages, 426 KiB  
Review
Survey on the Application of Robotics in Archaeology
by Panagiota Kyriakoulia, Anastasios Kazolias, Dimitrios Konidaris and Panagiotis Kokkinos
Sensors 2025, 25(15), 4836; https://doi.org/10.3390/s25154836 - 6 Aug 2025
Abstract
This work explores the application of robotic systems in archaeology, highlighting their transformative role in excavation, documentation, and the preservation of cultural heritage. By combining technologies such as LiDAR, GIS, 3D modeling, sonar, and other sensors with autonomous and semi-autonomous platforms, archaeologists can [...] Read more.
This work explores the application of robotic systems in archaeology, highlighting their transformative role in excavation, documentation, and the preservation of cultural heritage. By combining technologies such as LiDAR, GIS, 3D modeling, sonar, and other sensors with autonomous and semi-autonomous platforms, archaeologists can now reach inaccessible sites, automate artifact analysis, and reconstruct fragmented remains with greater precision. The study provides a systematic overview of underwater, aerial, terrestrial, and other robotic systems, drawing on scientific literature that showcases their innovative use in both fieldwork and museum settings. Selected examples illustrate how robotics is being applied to solve key archaeological challenges in new and effective ways. While the paper emphasizes the potential of these technologies, it also addresses their technical, economic, and ethical limitations, concluding that successful adoption depends on interdisciplinary collaboration, careful implementation, and a balanced respect for cultural integrity. Full article
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13 pages, 224 KiB  
Review
Cultural, Religious, and Spiritual Influences on Communication in Pediatric Palliative Care: A Narrative Review Focused on Children with Severe Neurological Conditions
by Francesca Benedetti, Luca Giacomelli, Simonetta Papa, Viviana Verzeletti and Caterina Agosto
Children 2025, 12(8), 1033; https://doi.org/10.3390/children12081033 - 6 Aug 2025
Abstract
Pediatric palliative care (PPC) aims to enhance the quality of life of children with life-limiting conditions and their families through individualized, interdisciplinary support. Among this population, children with neurological diseases represent a substantial and growing group, often facing prolonged disease courses, cognitive impairment, [...] Read more.
Pediatric palliative care (PPC) aims to enhance the quality of life of children with life-limiting conditions and their families through individualized, interdisciplinary support. Among this population, children with neurological diseases represent a substantial and growing group, often facing prolonged disease courses, cognitive impairment, and high prognostic uncertainty. Effective communication is central to PPC; however, it remains deeply influenced by cultural, religious, and spiritual frameworks that shape family perceptions of illness, suffering, and decision-making. This narrative review explores communication strategies in PPC, with a specific focus on children with neurological conditions, highlighting conceptual foundations, cross-cultural variations, and emerging best practices. Key findings highlight the importance of culturally humble approaches, family-centered communication models, and structured tools, such as co-designed advance care planning and dignity therapy, to enhance communication. Additionally, the review highlights the presence of ethical and interdisciplinary challenges, particularly in neonatal and neurology settings, where misaligned team messaging and institutional hesitancy may compromise trust and timely referral to palliative care. Future research, policy, and clinical education priorities should advocate for models that are inclusive, ethically grounded, and tailored to the unique trajectories of neurologically ill children. Integrating cultural competence, team alignment, and family voices is essential for delivering equitable and compassionate PPC across diverse care settings. Full article
(This article belongs to the Special Issue Pediatric Palliative Care and Pain Management)
24 pages, 1671 KiB  
Article
Sustainability in Purpose-Driven Businesses Operating in Cultural and Creative Industries: Insights from Consumers’ Perspectives on Società Benefit
by Gesualda Iodice and Francesco Bifulco
Sustainability 2025, 17(15), 7117; https://doi.org/10.3390/su17157117 - 6 Aug 2025
Abstract
This study intends to provide insights and challenges for the shape of the B movement, an emerging paradigm that fosters cross-sectoral partnerships and encourages ethical business practices through so-called purpose-driven businesses. Focusing on Italy, the first European country to adopt this managerial model, [...] Read more.
This study intends to provide insights and challenges for the shape of the B movement, an emerging paradigm that fosters cross-sectoral partnerships and encourages ethical business practices through so-called purpose-driven businesses. Focusing on Italy, the first European country to adopt this managerial model, the research investigates Italian Benefit Corporations, known as Società Benefit (SB), and their most appealing sustainability claims from a consumer perspective. The analysis intends to inform theory development by assuming the cultural and creative industry (CCI) as a field of interest, utilizing a within-subjects experimental design to analyze data from a diverse consumer sample across various contexts. The results indicate that messaging centered on economic sustainability emerged as the most effective in generating positive consumer responses, highlighting a prevailing inclination toward pragmatic factors such as affordability, economic accessibility, and tangible benefits rather than social issues. While sustainable behaviors are not yet widespread, latent ethical sensitivity for authentic, value-driven businesses suggests that economic and ethical dimensions can be strategically synthesized to enhance consumer engagement. This insight highlights the role of BCs in catalyzing a shift in consumption patterns within ethical-based and creative-driven sectors. Full article
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16 pages, 295 KiB  
Article
Humanized Care in Nursing Practice: A Phenomenological Study of Professional Experiences in a Public Hospital
by Monica Elisa Meneses-La-Riva, Víctor Hugo Fernández-Bedoya, Josefina Amanda Suyo-Vega, Hitler Giovanni Ocupa-Cabrera and Susana Edita Paredes-Díaz
Int. J. Environ. Res. Public Health 2025, 22(8), 1223; https://doi.org/10.3390/ijerph22081223 - 6 Aug 2025
Abstract
This study aims to understand the meaning nursing professionals attribute to their lived experiences of providing humanized care within a public hospital setting. Grounded in Jean Watson’s theory of human caring, the research adopts a qualitative, descriptive phenomenological design to capture the perceptions [...] Read more.
This study aims to understand the meaning nursing professionals attribute to their lived experiences of providing humanized care within a public hospital setting. Grounded in Jean Watson’s theory of human caring, the research adopts a qualitative, descriptive phenomenological design to capture the perceptions and emotions of nurses regarding humanized care. Data were collected through semi-structured interviews with nine experienced nurses, selected through purposive sampling. The interviews, conducted virtually between July and December 2024, were analyzed using Colaizzi’s method and supported by Atlas.ti software. Four main thematic categories emerged: institutional health policies, professional image and identity, strengths and challenges in care, and essential competencies for humanized care. The findings highlight the critical role of empathy, cultural sensitivity, ethical commitment, and emotional presence in delivering compassionate care. Participants emphasized that, beyond clinical procedures, humanized care requires relational and contextual sensitivity, often hindered by institutional limitations and excessive administrative burdens. The study concludes that nursing professionals are key agents in promoting ethical, empathetic, and culturally respectful practices that humanize health services. These insights offer valuable contributions for designing policies and training strategies aimed at strengthening humanized care as a cornerstone of quality healthcare systems. Full article
(This article belongs to the Special Issue Nursing Practice in Primary Health Care)
23 pages, 930 KiB  
Article
The Principle of Shared Utilization of Benefits Applied to the Development of Artificial Intelligence
by Camilo Vargas-Machado and Andrés Roncancio Bedoya
Philosophies 2025, 10(4), 87; https://doi.org/10.3390/philosophies10040087 - 5 Aug 2025
Viewed by 91
Abstract
This conceptual position is based on the diagnosis that artificial intelligence (AI) accentuates existing economic and geopolitical divides in communities in the Global South, which provide data without receiving rewards. Based on bioethical precedents of fair distribution of genetic resources, it is proposed [...] Read more.
This conceptual position is based on the diagnosis that artificial intelligence (AI) accentuates existing economic and geopolitical divides in communities in the Global South, which provide data without receiving rewards. Based on bioethical precedents of fair distribution of genetic resources, it is proposed to transfer the principle of benefit-sharing to the emerging algorithmic governance in the context of AI. From this discussion, the study reveals an algorithmic concentration in the Global North. This dynamic generates political, cultural, and labor asymmetries. Regarding the methodological design, the research was qualitative, with an interpretive paradigm and an inductive method, applying documentary review and content analysis techniques. In addition, two theoretical and two analytical categories were used. As a result, six emerging categories were identified that serve as pillars of the studied principle and are capable of reversing the gaps: equity, accessibility, transparency, sustainability, participation, and cooperation. At the end of the research, it was confirmed that AI, without a solid ethical framework, concentrates benefits in dominant economies. Therefore, if this trend does not change, the Global South will become dependent, and its data will lack equitable returns. Therefore, benefit-sharing is proposed as a normative basis for fair, transparent, and participatory international governance. Full article
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18 pages, 797 KiB  
Article
On Becoming a Senior Staff Nurse in Taiwan: A Narrative Study
by Yu-Jen Hsieh and Yu-Tzu Dai
Healthcare 2025, 13(15), 1896; https://doi.org/10.3390/healthcare13151896 - 4 Aug 2025
Viewed by 213
Abstract
Background/Objectives: Senior nurses in Taiwan shoulder layered responsibilities shaped by professional roles, gendered expectations, and family duty. Although Taiwan faces a persistent shortage of experienced clinical nurses, limited research has explored how long-serving nurses sustain identity and commitment across decades of caregiving. [...] Read more.
Background/Objectives: Senior nurses in Taiwan shoulder layered responsibilities shaped by professional roles, gendered expectations, and family duty. Although Taiwan faces a persistent shortage of experienced clinical nurses, limited research has explored how long-serving nurses sustain identity and commitment across decades of caregiving. This study examines how senior staff nurses understand their journeys of becoming—and remaining—nurses within a culturally and emotionally complex landscape. Methods: Interviews were conducted between May 2019 and September 2023 in locations chosen by participants, with most sessions face-to-face and others undertaken via video conferencing during COVID-19. This narrative inquiry involved in-depth, multi-session interviews with five female senior staff nurses born in the 1970s to early 1980s. Each participant reflected on her life and career, supported by co-constructed “nursing life lines.” Thematic narrative analysis was conducted using McCormack’s five-lens framework and Riessman’s model, with ethical rigor ensured through reflexive journaling and participant validation. Results: Three overarching themes emerged: (1) inner strength and endurance, highlighting silent resilience and the ethical weight of caregiving; (2) support and responsibility in relationships, revealing the influence of family, faith, and relational duty; and (3) role navigation and professional identity, showing how nurses revisit meaning, self-understanding, and tensions across time. Participants described emotionally powerful moments, identity re-connection, and cultural values that shaped their paths. Conclusions: These narratives offer a relational and culturally embedded understanding of what it means to sustain a career in nursing. Narrative inquiry created space for reflection, meaning-making, and voice in a system where such voices are often unheard. Identity was not static—it was lived, reshaped, and held in story. Full article
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21 pages, 26631 KiB  
Technical Note
Induced Polarization Imaging: A Geophysical Tool for the Identification of Unmarked Graves
by Matthias Steiner and Adrián Flores Orozco
Remote Sens. 2025, 17(15), 2687; https://doi.org/10.3390/rs17152687 - 3 Aug 2025
Viewed by 207
Abstract
The identification of unmarked graves is important in archaeology, forensics, and cemetery management, but invasive methods are often restricted due to ethical or cultural concerns. This necessitates the use of non-invasive geophysical techniques. Our study demonstrates the potential of induced polarization (IP) imaging [...] Read more.
The identification of unmarked graves is important in archaeology, forensics, and cemetery management, but invasive methods are often restricted due to ethical or cultural concerns. This necessitates the use of non-invasive geophysical techniques. Our study demonstrates the potential of induced polarization (IP) imaging as a non-invasive remote sensing technique specifically suited for detecting and characterizing unmarked graves. IP leverages changes in the electrical properties of soil and pore water, influenced by the accumulation of organic matter from decomposition processes. Measurements were conducted at an inactive cemetery using non-invasive textile electrodes to map a documented grave from the early 1990s, with a survey design optimized for high spatial resolution. The results reveal a distinct polarizable anomaly at a 0.75–1.0 m depth with phase shifts exceeding 12 mrad, attributed to organic carbon from wooden burial boxes, and a plume-shaped conductive anomaly indicating the migration of dissolved organic matter. While electrical conductivity alone yielded diffuse grave boundaries, the polarization response sharply delineated the grave, aligning with photographic documentation. These findings underscore the value of IP imaging as a non-invasive, data-driven approach for the accurate localization and characterization of graves. The methodology presented here offers a promising new tool for archaeological prospection and forensic search operations, expanding the geophysical toolkit available for remote sensing in culturally and legally sensitive contexts. Full article
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14 pages, 854 KiB  
Systematic Review
The Critical Impact and Socio-Ethical Implications of AI on Content Generation Practices in Media Organizations
by Sevasti Lamprou, Paraskevi (Evi) Dekoulou and George Kalliris
Societies 2025, 15(8), 214; https://doi.org/10.3390/soc15080214 - 1 Aug 2025
Viewed by 281
Abstract
This systematic literature review explores the socio-ethical implications of Artificial Intelligence (AI) in contemporary media content generation. Drawing from 44 peer-reviewed sources, policy documents, and industry reports, the study synthesizes findings across three core domains: bias detection, storytelling transformation, and ethical governance frameworks. [...] Read more.
This systematic literature review explores the socio-ethical implications of Artificial Intelligence (AI) in contemporary media content generation. Drawing from 44 peer-reviewed sources, policy documents, and industry reports, the study synthesizes findings across three core domains: bias detection, storytelling transformation, and ethical governance frameworks. Through thematic coding and structured analysis, the review identifies recurring tensions between automation and authenticity, efficiency and editorial integrity, and innovation and institutional oversight. It introduces the Human–AI Co-Creation Continuum as a conceptual model for understanding hybrid narrative production and proposes practical recommendations for ethical AI adoption in journalism. The review concludes with a future research agenda emphasizing empirical studies, cross-cultural governance models, and audience perceptions of AI-generated content. This aligns with prior studies on algorithmic journalism. Full article
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26 pages, 4349 KiB  
Article
Palazzo Farnese and Dong’s Fortified Compound: An Art-Anthropological Cross-Cultural Analysis of Architectural Form, Symbolic Ornamentation, and Public Perception
by Liyue Wu, Qinchuan Zhan, Yanjun Li and Chen Chen
Buildings 2025, 15(15), 2720; https://doi.org/10.3390/buildings15152720 - 1 Aug 2025
Viewed by 156
Abstract
This study presents a cross-cultural comparison of two fortified residences—Palazzo Farnese in Italy and Dong’s Fortified Compound in China—through a triadic analytical framework encompassing architectural form, symbolic ornamentation, and public perception. By combining field observation, iconographic interpretation, and digital ethnography, the research investigates [...] Read more.
This study presents a cross-cultural comparison of two fortified residences—Palazzo Farnese in Italy and Dong’s Fortified Compound in China—through a triadic analytical framework encompassing architectural form, symbolic ornamentation, and public perception. By combining field observation, iconographic interpretation, and digital ethnography, the research investigates how heritage meaning is constructed, encoded, and reinterpreted across distinct sociocultural contexts. Empirical materials include architectural documentation, decorative analysis, and a curated dataset of 4947 user-generated images and 1467 textual comments collected from Chinese and international platforms between 2020 and 2024. Methods such as CLIP-based visual clustering and BERTopic-enabled sentiment modelling were applied to extract patterns of perception and symbolic emphasis. The findings reveal contrasting representational logics: Palazzo Farnese encodes dynastic authority and Renaissance cosmology through geometric order and immersive frescoes, while Dong’s Compound conveys Confucian ethics and frontier identity via nested courtyards and traditional ornamentation. Digital responses diverge accordingly: international users highlight formal aesthetics and photogenic elements; Chinese users engage with symbolic motifs, family memory, and ritual significance. This study illustrates how historically fortified residences are reinterpreted through culturally specific digital practices, offering an interdisciplinary approach that bridges architectural history, symbolic analysis, and digital heritage studies. Full article
(This article belongs to the Section Architectural Design, Urban Science, and Real Estate)
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18 pages, 373 KiB  
Article
Surrendering to and Transcending Ming 命 in the Analects, Mencius and Zhuangzi
by Ying Zhou
Religions 2025, 16(8), 1000; https://doi.org/10.3390/rel16081000 - 31 Jul 2025
Viewed by 206
Abstract
This article examines the concept of ming 命 (mandate/command or fate/destiny) in the Analects, Mencius, and Zhuangzi, exploring its relationship to tian 天 (Heaven). Across these works, ming retains an intrinsic connection to tian—an inviolable cosmic force beyond human [...] Read more.
This article examines the concept of ming 命 (mandate/command or fate/destiny) in the Analects, Mencius, and Zhuangzi, exploring its relationship to tian 天 (Heaven). Across these works, ming retains an intrinsic connection to tian—an inviolable cosmic force beyond human control. All three texts exhibit profound reverence and submission to tian, acknowledging the boundary between human control and cosmic inevitability, yet, at the same time, advocating active alignment with tian’s ordained patterns. In the Analects, a central tension emerges between tian’s teleological purpose—centered on preserving human culture and ethical cultivation—and the seemingly arbitrary fluctuations of individual fate, particularly regarding lifespan and personal fulfillment. This tension persists in the Mencius, articulated as a conflict between the political disorder of Mencius’ contemporary era and tian’s normative moral order. The Zhuangzi, by contrast, resolves this tension through advocating for withdrawal from the political life, as well as a radical reinterpretation of tian. Stripping tian off the Confucian moral–cultural imperatives, the text deconstructs dichotomies like life and death, championing inner equanimity via flowing with the cosmic transformation. Full article
15 pages, 299 KiB  
Article
Adaptation and Validation of the Compassionate Capacity Scale for Portuguese Healthcare Students (CCS-PHS)
by María Dolores Ruiz-Fernández, Andrea Alcaraz-Córdoba, Irma Brito, Maria Jacinta Dantas, Tania Alcaraz-Córdoba and Angela María Ortega-Galán
Behav. Sci. 2025, 15(8), 1039; https://doi.org/10.3390/bs15081039 - 31 Jul 2025
Viewed by 248
Abstract
Compassion is a critical competence for university students in the healthcare field when dealing with the suffering of patients and relatives. However, there are no tools that measure compassionate capacity during students’ training. Recently, the Compassion Capacity Scale (CCS) was developed for health [...] Read more.
Compassion is a critical competence for university students in the healthcare field when dealing with the suffering of patients and relatives. However, there are no tools that measure compassionate capacity during students’ training. Recently, the Compassion Capacity Scale (CCS) was developed for health professionals, exhibiting good psychometric properties. The aim of this study was to translate, culturally adapt, and validate the CCS for Portuguese university students in the healthcare field. The study was divided into two phases: (1) translation and adaptation of the CCS for Portuguese university students in the healthcare field; (2) validation and analysis of psychometric properties. The CCS-PHS showed good internal consistency (Cronbach’s α = 0.886), temporal stability (rho = 0.703), and content validity (CVI-i = 1). Criterion validity analysis showed strong correlations between all of the CCS-PHS’s dimensions and the chosen reference criteria scale. Construct validity analysis revealed that the CCS-PHS is composed of 17 items, classified into four factors. The differences found in the exploratory factor analysis in relation to the original scale may be due to the differences in the life experiences of healthcare professionals when compared to those of students. Our psychometric analysis suggests that the CCS-PHS is a reliable and valid tool to assess compassionate capacity in healthcare students. Knowing the compassionate competence of students is vital for guiding educational strategies, implementing compassion training programs and evaluating their effectiveness, as well as reinforcing key attitudes and behaviors for humanized and ethical healthcare. Full article
16 pages, 628 KiB  
Article
Beyond the Bot: A Dual-Phase Framework for Evaluating AI Chatbot Simulations in Nursing Education
by Phillip Olla, Nadine Wodwaski and Taylor Long
Nurs. Rep. 2025, 15(8), 280; https://doi.org/10.3390/nursrep15080280 - 31 Jul 2025
Viewed by 247
Abstract
Background/Objectives: The integration of AI chatbots in nursing education, particularly in simulation-based learning, is advancing rapidly. However, there is a lack of structured evaluation models, especially to assess AI-generated simulations. This article introduces the AI-Integrated Method for Simulation (AIMS) evaluation framework, a dual-phase [...] Read more.
Background/Objectives: The integration of AI chatbots in nursing education, particularly in simulation-based learning, is advancing rapidly. However, there is a lack of structured evaluation models, especially to assess AI-generated simulations. This article introduces the AI-Integrated Method for Simulation (AIMS) evaluation framework, a dual-phase evaluation framework adapted from the FAITA model, designed to evaluate both prompt design and chatbot performance in the context of nursing education. Methods: This simulation-based study explored the application of an AI chatbot in an emergency planning course. The AIMS framework was developed and applied, consisting of six prompt-level domains (Phase 1) and eight performance criteria (Phase 2). These domains were selected based on current best practices in instructional design, simulation fidelity, and emerging AI evaluation literature. To assess the chatbots educational utility, the study employed a scoring rubric for each phase and incorporated a structured feedback loop to refine both prompt design and chatbox interaction. To demonstrate the framework’s practical application, the researchers configured an AI tool referred to in this study as “Eval-Bot v1”, built using OpenAI’s GPT-4.0, to apply Phase 1 scoring criteria to a real simulation prompt. Insights from this analysis were then used to anticipate Phase 2 performance and identify areas for improvement. Participants (three individuals)—all experienced healthcare educators and advanced practice nurses with expertise in clinical decision-making and simulation-based teaching—reviewed the prompt and Eval-Bot’s score to triangulate findings. Results: Simulated evaluations revealed clear strengths in the prompt alignment with course objectives and its capacity to foster interactive learning. Participants noted that the AI chatbot supported engagement and maintained appropriate pacing, particularly in scenarios involving emergency planning decision-making. However, challenges emerged in areas related to personalization and inclusivity. While the chatbot responded consistently to general queries, it struggled to adapt tone, complexity and content to reflect diverse learner needs or cultural nuances. To support replication and refinement, a sample scoring rubric and simulation prompt template are provided. When evaluated using the Eval-Bot tool, moderate concerns were flagged regarding safety prompts and inclusive language, particularly in how the chatbot navigated sensitive decision points. These gaps were linked to predicted performance issues in Phase 2 domains such as dialog control, equity, and user reassurance. Based on these findings, revised prompt strategies were developed to improve contextual sensitivity, promote inclusivity, and strengthen ethical guidance within chatbot-led simulations. Conclusions: The AIMS evaluation framework provides a practical and replicable approach for evaluating the use of AI chatbots in simulation-based education. By offering structured criteria for both prompt design and chatbot performance, the model supports instructional designers, simulation specialists, and developers in identifying areas of strength and improvement. The findings underscore the importance of intentional design, safety monitoring, and inclusive language when integrating AI into nursing and health education. As AI tools become more embedded in learning environments, this framework offers a thoughtful starting point for ensuring they are applied ethically, effectively, and with learner diversity in mind. Full article
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31 pages, 3754 KiB  
Review
Artificial Gametogenesis and In Vitro Spermatogenesis: Emerging Strategies for the Treatment of Male Infertility
by Aris Kaltsas, Maria-Anna Kyrgiafini, Eleftheria Markou, Andreas Koumenis, Zissis Mamuris, Fotios Dimitriadis, Athanasios Zachariou, Michael Chrisofos and Nikolaos Sofikitis
Int. J. Mol. Sci. 2025, 26(15), 7383; https://doi.org/10.3390/ijms26157383 - 30 Jul 2025
Viewed by 478
Abstract
Male-factor infertility accounts for approxiamately half of all infertility cases globally, yet therapeutic options remain limited for individuals with no retrievable spermatozoa, such as those with non-obstructive azoospermia (NOA). In recent years, artificial gametogenesis has emerged as a promising avenue for fertility restoration, [...] Read more.
Male-factor infertility accounts for approxiamately half of all infertility cases globally, yet therapeutic options remain limited for individuals with no retrievable spermatozoa, such as those with non-obstructive azoospermia (NOA). In recent years, artificial gametogenesis has emerged as a promising avenue for fertility restoration, driven by advances in two complementary strategies: organotypic in vitro spermatogenesis (IVS), which aims to complete spermatogenesis ex vivo using native testicular tissue, and in vitro gametogenesis (IVG), which seeks to generate male gametes de novo from pluripotent or reprogrammed somatic stem cells. To evaluate the current landscape and future potential of these approaches, a narrative, semi-systematic literature search was conducted in PubMed and Scopus for the period January 2010 to February 2025. Additionally, landmark studies published prior to 2010 that contributed foundational knowledge in spermatogenesis and testicular tissue modeling were reviewed to provide historical context. This narrative review synthesizes multidisciplinary evidence from cell biology, tissue engineering, and translational medicine to benchmark IVS and IVG technologies against species-specific developmental milestones, ranging from rodent models to non-human primates and emerging human systems. Key challenges—such as the reconstitution of the blood–testis barrier, stage-specific endocrine signaling, and epigenetic reprogramming—are discussed alongside critical performance metrics of various platforms, including air–liquid interface slice cultures, three-dimensional organoids, microfluidic “testis-on-chip” devices, and stem cell-derived gametogenic protocols. Particular attention is given to clinical applicability in contexts such as NOA, oncofertility preservation in prepubertal patients, genetic syndromes, and reprocutive scenarios involving same-sex or unpartnered individuals. Safety, regulatory, and ethical considerations are critically appraised, and a translational framework is outlined that emphasizes biomimetic scaffold design, multi-omics-guided media optimization, and rigorous genomic and epigenomic quality control. While the generation of functionally mature sperm in vitro remains unachieved, converging progress in animal models and early human systems suggests that clinically revelant IVS and IVG applications are approaching feasibility, offering a paradigm shift in reproductive medicine. Full article
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42 pages, 2643 KiB  
Article
Personalized Constitutionally-Aligned Agentic Superego: Secure AI Behavior Aligned to Diverse Human Values
by Nell Watson, Ahmed Amer, Evan Harris, Preeti Ravindra and Shujun Zhang
Information 2025, 16(8), 651; https://doi.org/10.3390/info16080651 - 30 Jul 2025
Viewed by 140
Abstract
Agentic AI systems, possessing capabilities for autonomous planning and action, show great potential across diverse domains. However, their practical deployment is hindered by challenges in aligning their behavior with varied human values, complex safety requirements, and specific compliance needs. Existing alignment methodologies often [...] Read more.
Agentic AI systems, possessing capabilities for autonomous planning and action, show great potential across diverse domains. However, their practical deployment is hindered by challenges in aligning their behavior with varied human values, complex safety requirements, and specific compliance needs. Existing alignment methodologies often falter when faced with the complex task of providing personalized context without inducing confabulation or operational inefficiencies. This paper introduces a novel solution: a ‘superego’ agent, designed as a personalized oversight mechanism for agentic AI. This system dynamically steers AI planning by referencing user-selected ‘Creed Constitutions’—encapsulating diverse rule sets—with adjustable adherence levels to fit non-negotiable values. A real-time compliance enforcer validates plans against these constitutions and a universal ethical floor before execution. We present a functional system, including a demonstration interface with a prototypical constitution-sharing portal, and successful integration with third-party models via the Model Context Protocol (MCP). Comprehensive benchmark evaluations (HarmBench, AgentHarm) demonstrate that our Superego agent dramatically reduces harmful outputs—achieving up to a 98.3% harm score reduction and near-perfect refusal rates (e.g., 100% with Claude Sonnet 4 on AgentHarm’s harmful set) for leading LLMs like Gemini 2.5 Flash and GPT-4o. This approach substantially simplifies personalized AI alignment, rendering agentic systems more reliably attuned to individual and cultural contexts, while also enabling substantial safety improvements. Full article
(This article belongs to the Special Issue New Information Communication Technologies in the Digital Era)
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20 pages, 1320 KiB  
Article
Emotional Intelligence in the Professional Development of Nurses: From Training to the Improvement of Healthcare Quality
by Efthymia Chatzidimitriou, Sotiria Triantari and Ioannis Zervas
Nurs. Rep. 2025, 15(8), 275; https://doi.org/10.3390/nursrep15080275 - 30 Jul 2025
Viewed by 624
Abstract
Background/Objectives: Emotional intelligence has emerged as a key factor in shaping nursing performance and care quality, yet its specific mechanisms and impact within the Greek public healthcare context remain underexplored. This study aimed to investigate the role of emotional intelligence in ethical [...] Read more.
Background/Objectives: Emotional intelligence has emerged as a key factor in shaping nursing performance and care quality, yet its specific mechanisms and impact within the Greek public healthcare context remain underexplored. This study aimed to investigate the role of emotional intelligence in ethical behavior, crisis management, and the perceived quality of care among nurses working in Greek public hospitals. Methods: A cross-sectional survey was conducted among practicing nurses using validated instruments to assess emotional intelligence, ethical compliance, crisis management skills, and care quality. Data were analyzed using covariance-based structural equation modeling (CB SEM) to examine both direct and indirect relationships among variables. Results: The results indicated that emotional intelligence training had a strong and significant effect on nurses’ ethical behavior and their ability to manage critical situations. However, the direct effect of emotional intelligence on the perceived quality of care was not significant; instead, its influence was mediated through improvements in ethics and crisis management. Conclusions: These findings suggest that the benefits of emotional intelligence in nursing are most evident when integrated with supportive organizational practices and ongoing professional development. Overall, this study highlights the need for comprehensive emotional intelligence training and a supportive workplace culture to enhance ethical standards, resilience, and patient care quality in Greek healthcare settings. Full article
(This article belongs to the Special Issue Nursing Leadership: Contemporary Challenges)
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