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Keywords = ergogenic-aids

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17 pages, 2003 KiB  
Article
Effect of Caffeinated Chewing Gum on Maximal Strength, Muscular Power, and Muscle Recruitment During Bench Press and Back Squat Exercises
by Li Ding, Jue Liu, Yixuan Ma, Tze-Huan Lei, Mathew Barnes, Li Guo, Bin Chen, Yinhang Cao and Olivier Girard
Nutrients 2025, 17(15), 2455; https://doi.org/10.3390/nu17152455 - 28 Jul 2025
Viewed by 504
Abstract
Background/Objectives: This study aims to investigate the effects of caffeinated chewing gum on maximal strength, muscular power, and neural drive to the prime movers during bench press and back squat in resistance-trained men. Methods: Sixteen resistance-trained males participated in a double-blind, [...] Read more.
Background/Objectives: This study aims to investigate the effects of caffeinated chewing gum on maximal strength, muscular power, and neural drive to the prime movers during bench press and back squat in resistance-trained men. Methods: Sixteen resistance-trained males participated in a double-blind, randomized trial, chewing either caffeinated gum (4 mg/kg) or placebo gum on two separate occasions, seven days apart. After chewing for 5 min, participants performed a maximal strength test followed by muscular power assessments at 25%, 50%, 75%, and 90% of their one-repetition maximum (1RM), completing with 3, 2, 1, and 1 repetition (s), respectively, for bench press and back squat. Surface electromyography data were recorded for each repetition. Results: Caffeinated gum did not significantly improve one-repetition maximum (1RM) for bench press (p > 0.05), but increased mean frequency (MF) and median frequency (MDF) in anterior deltoid, pectoralis major, and biceps brachii (all p < 0.05) compared to placebo. For back squat, 1RM increased with caffeinated gum, along with higher MF and MDF in vastus medialis (all p < 0.05). Caffeinated gum also improved mean and peak velocities, and mean and peak power outputs at 25–75% 1RM during the bench press (all p < 0.05), along with elevated MDF in pectoralis major and biceps brachii (all p < 0.05). Similar improvements were seen in mean and peak velocities during the back squat at 25–90% 1RM (all p < 0.05), along with higher MF and MDF in vastus medialis and increased normalized root mean square activity in gluteus maximus (all p < 0.05). Conclusions: Caffeinated chewing gum (4 mg/kg) enhanced muscular power (25–75% 1RM) in the bench press and improved maximal strength and muscular power (25–90% 1RM) in the back squat by increasing muscle recruitment in resistance-trained men. Full article
(This article belongs to the Special Issue Energy Drink Effectiveness on Human Health and Exercise Performance)
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22 pages, 527 KiB  
Article
Impact of Chronic Nitrate and Citrulline Malate Supplementation on Performance and Recovery in Spanish Professional Female Soccer Players: A Randomized Controlled Trial
by Marta Ramírez-Munera, Raúl Arcusa, Francisco Javier López-Román, Vicente Ávila-Gandía, Silvia Pérez-Piñero, Juan Carlos Muñoz-Carrillo, Antonio Jesús Luque-Rubia and Javier Marhuenda
Nutrients 2025, 17(14), 2381; https://doi.org/10.3390/nu17142381 - 21 Jul 2025
Viewed by 687
Abstract
Background: Pre-season training is critical for developing tolerance to high physical demands in professional soccer, and nitric oxide (NO) precursors such as dietary nitrate (NO3) and citrulline malate (CM) can support performance and recovery during this demanding phase. This [...] Read more.
Background: Pre-season training is critical for developing tolerance to high physical demands in professional soccer, and nitric oxide (NO) precursors such as dietary nitrate (NO3) and citrulline malate (CM) can support performance and recovery during this demanding phase. This study aimed to examine the effects of a four-week supplementation protocol combining 500 mg of NO3 from amaranth extract and 8 g of CM (NIT + CM) on external training load and post-match recovery in professional female soccer players during pre-season. Methods: A randomized, double-blind, placebo-controlled trial was conducted with 34 female soccer players who received either the NIT + CM product or a placebo for four weeks during pre-season. Global positioning system (GPS)-derived external load was recorded throughout the intervention. Performance tests—a countermovement jump (CMJ) test and the Wingate anaerobic test (WAnT)—and blood sampling for plasma NO3 and nitrite (NO2) concentrations were conducted at baseline and the day after a competitive match. Results: The supplementation with NIT + CM increased maximal speed (Vmax) throughout training and match play. During post-match testing, the NIT + CM group exhibited a significantly smaller decline in mean (Pmean) and minimum (Pmin) power during the WAnT, along with reduced power loss in both the first (0–15 s) and second (15–30 s) intervals. Plasma NO3 concentrations significantly increased from baseline in the NIT + CM group and remained elevated 24 h after the final dose, confirming sustained systemic exposure. Conclusions: Chronic NIT + CM supplementation may enhance Vmax and help preserve anaerobic performance the day after a match. These effects could reflect improved tolerance to high training loads and sustained NO3 availability during recovery. Full article
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14 pages, 879 KiB  
Review
Implications for the Ergogenic Benefits of Self-Selected Music in Neurological Conditions: A Theoretical Review
by Christopher G. Ballmann, Rebecca R. Rogers, Sophia L. Porrill and Nicholas B. Washmuth
Neurol. Int. 2025, 17(7), 106; https://doi.org/10.3390/neurolint17070106 - 11 Jul 2025
Viewed by 290
Abstract
The ergogenic effects of music have been well described across various modes of exercise with widespread use across competitive athletes and recreational exercisers alike. Underlying the acute beneficial effects of music during exercise are profound physiological and psychological changes which involve an array [...] Read more.
The ergogenic effects of music have been well described across various modes of exercise with widespread use across competitive athletes and recreational exercisers alike. Underlying the acute beneficial effects of music during exercise are profound physiological and psychological changes which involve an array of different organ systems, including but not limited to cardiovascular, endocrine, skeletal muscle, and nervous systems. While the use of music to enhance physical performance and improve associated mechanisms has been largely optimized in healthy individuals, the investigations of the translation to individuals with neurological conditions are still ongoing. Recently, it has been established that the personalization of music interventions greatly influences performance-enhancing benefits and aids in physical performance optimization in healthy individuals. Self-selected music (SSM) has been documented to impart ergogenic advantages over pre-determined or non-preferred music, including improved cardiorespiratory endurance, power development, and velocity of movement which are characterized by adaptative physiological and psychological changes. Evidence of the benefits of SSM has progressed to the degree to which the overlap of possible benefits between healthy and clinical populations is becoming more apparent. This aim of this theoretical review is to discuss how personalized music influences psychophysiological determinants of exercise ability in healthy individuals and consider how these findings may be applicable to neurological conditions to enhance exercise capacity. The current knowledge on the role of SSM in augmenting physiological and psychological responses to exercise in healthy individuals is presented along with how these mechanisms might be leveraged to overcome exercise limitations in neurological conditions. Overall, SSM appears to have theoretical support to be a promising therapeutic approach to improving exercise ability in neurological conditions through similar ergogenic mechanisms documented in healthy individuals, but further investigation is warranted. Full article
(This article belongs to the Section Movement Disorders and Neurodegenerative Diseases)
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12 pages, 243 KiB  
Article
Effects of Eight Weeks of Aerobic Training Combined with Carbohydrate Mouth Rinse on Body Composition and Exercise Performance in Adult Men with Obesity: Evidence from Korea
by Jae-Myun Ko, Wi-Young So and Sung-Eun Park
Metabolites 2025, 15(7), 455; https://doi.org/10.3390/metabo15070455 - 5 Jul 2025
Viewed by 540
Abstract
Background: Considering that the prevalence of obesity has risen rapidly in recent decades, the aim of this study was to investigate the effects of a carbohydrate mouth rinse (CMR) on the outcomes of aerobic training among adult men with obesity, focusing particularly on [...] Read more.
Background: Considering that the prevalence of obesity has risen rapidly in recent decades, the aim of this study was to investigate the effects of a carbohydrate mouth rinse (CMR) on the outcomes of aerobic training among adult men with obesity, focusing particularly on the effects of repeated use on body composition and exercise performance. Methods: The intervention targeted 20 men with obesity in their 20s and 30s randomly assigned to either a CMR group (n = 10) or a placebo mouth rinse (PMR) group (n = 10). Both groups completed treadmill-based aerobic training three times per week for eight weeks. Prior to each session, participants used a mouth rinse at 60, 40, and 20 s before the start of each exercise, holding either a 6% maltodextrin solution (CMR) or purified water (PMR) in their mouths for 5 to 10 s before expectorating. Pre- and post-intervention assessments included body composition (body weight and body fat percentage), resting metabolic rate (RMR), maximal oxygen uptake (VO2max), and exercise performance (rate of perceived exertion [RPE], exercise distance, speed, and time). Data were analyzed using 2 × 2 repeated measures analysis of variance. Results: Following the intervention, the CMR group showed significantly greater improvements than the PMR group did in body fat percentage, RMR, VO2max, exercise distance, speed, and time (p < 0.01). However, the interaction effect for RPE was not statistically significant between the groups (p = 0.175). Overall, the repeated use of the CMR during aerobic training contributed to enhanced exercise performance and favorable physiological changes without additional caloric intake. Conclusions: A CMR may be a practical and non-caloric ergogenic aid to support exercise performance and metabolic function in individuals with obesity. Its repeated use during aerobic training appears to be effective and safe, especially when fasting while exercising, when improving endurance without compromising fat loss is essential. Full article
(This article belongs to the Special Issue Effects of Various Exercise Methods on Metabolic Health)
16 pages, 460 KiB  
Article
Acute Effects of Nitrate-Rich Beetroot Juice on Cardiovascular and Hemodynamic Responses to Flywheel Resistance Exercise: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial
by Mateus Chaves Primo, Ítalo Santiago Alves Viana, Leonardo Silveira Goulart-Silva, Wanderson Matheus Lopes Machado, Luciano Bernardes Leite, Pedro Forte, Ricardo C. Calhelha, António M. Monteiro, Luís Branquinho, Sandro Fernandes da Silva, Claudia Eliza Patrocínio Oliveira and Osvaldo Costa Moreira
Physiologia 2025, 5(3), 20; https://doi.org/10.3390/physiologia5030020 - 28 Jun 2025
Viewed by 745
Abstract
Background/Objectives: Beetroot juice is a popular nutritional resource in sports due to its ergogenic effects, promoting vasodilation, hypotension, improved energy efficiency, and reduced oxygen cost. However, its role in modulating the autonomic nervous system during strength training remains understudied. This study assessed the [...] Read more.
Background/Objectives: Beetroot juice is a popular nutritional resource in sports due to its ergogenic effects, promoting vasodilation, hypotension, improved energy efficiency, and reduced oxygen cost. However, its role in modulating the autonomic nervous system during strength training remains understudied. This study assessed the effects of acute nitrate-rich beetroot juice supplementation on cardiovascular and hemodynamic responses to flywheel resistance exercise. Methods: Fifteen male participants (age 22 ± 3.64 years) from the Federal University of Viçosa completed a crossover, double-blind, placebo-controlled trial. Each participant consumed either 400 mg of standardized nitrate or a placebo before performing 4 sets of 8–12 repetitions at 100% of their maximum concentric strength using a leg extension exercise, with 90 s recovery intervals. Heart rate, blood pressure, oxygen saturation, and subjective perception of effort were measured after each set. Data were analyzed using SPSS 23, employing the Shapiro–Wilk normality test, t-test for related samples, and MANOVA with time and supplement factors. Results: NO3 supplementation led to a smaller increase in systolic blood pressure (SBP) during exercise compared to the placebo and reduced diastolic blood pressure (DBP) in the last set, reflecting decreased peripheral vascular resistance. However, no significant effects were observed for heart rate, rate–pressure product, oxygen saturation, time under tension, or subjective perception of effort. Conclusions: These findings suggest that NO3 supplementation can offer cardiovascular benefits by attenuating blood pressure increases during strength training, highlighting its potential as a low-risk ergogenic aid for healthy young men. Full article
(This article belongs to the Special Issue Exercise Physiology and Biochemistry: 2nd Edition)
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16 pages, 908 KiB  
Article
Melatonin Supplementation Enhances Next-Day High-Intensity Exercise Performance and Recovery in Trained Males: A Placebo-Controlled Crossover Study
by Nourhène Mahdi, Slaheddine Delleli, Arwa Jebabli, Khouloud Ben Maaoui, Juan Del Coso, Hamdi Chtourou, Luca Paolo Ardigò and Ibrahim Ouergui
Sports 2025, 13(6), 190; https://doi.org/10.3390/sports13060190 - 19 Jun 2025
Viewed by 1562
Abstract
Background/Objectives: Sleep and recovery are critical for optimising exercise performance. However, the efficacy of melatonin supplementation in improving sleep quality and next-day physical performance remains unclear. This study examined the effects of melatonin ingestion on sleep and performance-related outcomes the following day in [...] Read more.
Background/Objectives: Sleep and recovery are critical for optimising exercise performance. However, the efficacy of melatonin supplementation in improving sleep quality and next-day physical performance remains unclear. This study examined the effects of melatonin ingestion on sleep and performance-related outcomes the following day in trained males. Methods: In a randomised, double-blind, placebo-controlled crossover study, 12 trained males (age: 21.92 ± 2.84 years) ingested 6 mg of melatonin (MEL) or a placebo (PLA) the night before performing the 5 m shuttle test (5mSRT). Before and after the 5mSRT, blood samples were collected. Peak heart rate (HRpeak) and rating of perceived exertion (RPE) were recorded throughout the test. Perceived recovery status (PRS) and delayed onset muscle soreness (DOMS) were measured before, 5 min, 24 h, 48 h, and 72 h after the test. The sleep/wake cycle was monitored during the night after ingestion. Results: Data were analysed using paired t-tests, Wilcoxon tests, and two-way ANOVAs, with significance set at p < 0.05. Compared to PLA, MEL did not modify any sleep parameters or blood markers (all p > 0.05). However, MEL improved total distance, fatigue index, the percentage decrement between sprints, and HRpeak (all p < 0.05) in the 5mSRT compared to PLA. MEL also enhanced PRS values up to 72 h post-exercise and reduced DOMS (all p < 0.05). Conclusion: In summary, 6 mg of melatonin taken at night enhanced next-day high-intensity exercise performance and improved perceived recovery up to 72 h post-exercise. Full article
(This article belongs to the Special Issue Current Research in Applied Sports Nutrition)
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50 pages, 1936 KiB  
Review
Triathlon: Ergo Nutrition for Training, Competing, and Recovering
by Álvaro Miguel-Ortega, María-Azucena Rodríguez-Rodrigo, Juan Mielgo-Ayuso and Julio Calleja-González
Nutrients 2025, 17(11), 1846; https://doi.org/10.3390/nu17111846 - 28 May 2025
Viewed by 2444
Abstract
Triathlon is a multi-sport event that combines swimming, cycling and running. The distances vary and the physiological demands are high. Objectives: This review compiles information on nutritional strategies and ergogenic supplements for triathlon training, competition and recovery. It aims to provide an [...] Read more.
Triathlon is a multi-sport event that combines swimming, cycling and running. The distances vary and the physiological demands are high. Objectives: This review compiles information on nutritional strategies and ergogenic supplements for triathlon training, competition and recovery. It aims to provide an understanding of the specific challenges and needs of the sport to help triathletes and coaches optimise performance through effective training and nutrition plans. Methods: English-language publications were searched using the keywords triathlon, nutrition, recovery and ergogenic aids, alone or in combination, in databases. Results: Maintaining good glycogen levels, consuming enough carbohydrates and staying properly hydrated are key to athletic performance, especially for triathletes. Education regarding nutrition, the role of probiotics and supplements, and diet modification for the enhancement of performance and recovery are pivotal considerations. Conclusions: Triathletes are at risk of RED-S due to negative energy balance and high fibre/plant protein diets, especially women. Optimising muscle glycogen through tailored diet and training, especially pre- and in-race nutrition, including carbohydrate loading and hydration strategies, is critical. Education is needed to improve post-exercise nutrition, while probiotics and certain supplements may aid performance and recovery. Dietary support is important for resistance training to optimise performance and recovery. Full article
(This article belongs to the Special Issue New Strategies in Sport Nutrition: Enhancing Exercise Performance)
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17 pages, 2252 KiB  
Review
Part I: Development and Implementation of the Ten, Five, Three (TFT) Model for Resistance Training
by Quincy R. Johnson
Muscles 2025, 4(2), 14; https://doi.org/10.3390/muscles4020014 - 19 May 2025
Viewed by 1608
Abstract
The strength and conditioning literature examining neuromuscular physiology, bioenergetics, neuroendocrine factors, nutrition and metabolic factors, and the use of ergogenic aids, as well as physical and physiological responses and adaptations, have clearly identified the benefits of participating in regular resistance training programs for [...] Read more.
The strength and conditioning literature examining neuromuscular physiology, bioenergetics, neuroendocrine factors, nutrition and metabolic factors, and the use of ergogenic aids, as well as physical and physiological responses and adaptations, have clearly identified the benefits of participating in regular resistance training programs for athletic populations, especially as it relates to improving muscular strength. Beyond evidence-based research, models for resistance training program implementation are of considerable value for optimizing athletic performance. In fact, several have been provided that address general to specific characteristics of athleticism (i.e., strength endurance, muscular strength, and muscular power) through resistance training over the decades. For instance, a published model known as the strength–endurance continuum that enhances dynamic correspondence (i.e., training specificity) in athletic populations by developing structural, metabolic, and neural capacities across a high-load, low-repetition and low-load, high-repetition range. Further models have been developed to enhance performance approaches (i.e., optimum performance training model) and outcomes (i.e., performance pyramid), even within specific populations, such as youth (i.e., youth physical development model). The ten, five, three, or 10-5-3 (TFT) model for strength and conditioning professionals synthesizes currently available information and provides a framework for the effective implementation of resistance training approaches to suit the needs of athletes at each stage of development. The model includes three key components to consider when designing strength and conditioning programs, denoted by the acronym TFT (ten, five, three). Over recent years, the model has gained much support from teams, coaches, and athletes, mainly due to the ability to streamline common knowledge within the field into an efficient and effective resistance training system. Furthermore, this model is distinctly unique from others as it prioritizes the development of strength–endurance, muscular strength, and muscular power concurrently. This paper explains the model itself and begins to provide recommendations for those interested in implementing TFT-based approaches, including a summary of points as a brief take-home guide to implementing TFT interventions. It is the author’s hope that this paper encourages other performance professionals to share their models to appreciate human ingenuity and advance our understanding of individualized approaches and systems towards the physical development of the modern-day athlete. Full article
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15 pages, 4892 KiB  
Review
Effects of Caffeine Supplementation on Exercise Performance in Volleyball Players: A Systematic Review and Meta-Analysis
by Bin Chen, Chuanmin Zhang, Zhenghong Xu, Yiqian Li, Li Guo, Yinhang Cao and Olivier Girard
Nutrients 2025, 17(10), 1709; https://doi.org/10.3390/nu17101709 - 18 May 2025
Viewed by 2248
Abstract
Background/Objectives: The ergogenic effects of caffeine in team sports, particularly volleyball, have received significant research attention. This study sought to examine the effects of caffeine on both volleyball-specific and general performance outcomes. Methods: This systematic review comprises 11 studies, each utilizing a blinded [...] Read more.
Background/Objectives: The ergogenic effects of caffeine in team sports, particularly volleyball, have received significant research attention. This study sought to examine the effects of caffeine on both volleyball-specific and general performance outcomes. Methods: This systematic review comprises 11 studies, each utilizing a blinded crossover experimental design. A meta-analysis was conducted using a random-effect model to determine the standardized mean difference (SMD), estimated by Hedges’ g, with a 95% confidence interval (CI). Results: Caffeine supplementation improved volleyball-specific outcomes, including attack and serve accuracy (SMD: 0.50; 95% CI: 0.11–0.90; p = 0.01). Regarding nonspecific outcomes, caffeine increased single-jump performance (SMD: 0.23; 95% CI: 0.02–0.44; p = 0.03), repeated-jump performance (SMD: 0.51; 95% CI: 0.05–0.96; p = 0.03), and handgrip strength (SMD: 0.23; 95% CI: 0.03–0.42; p = 0.02), while decreasing agility test completion time (SMD: −0.32; 95% CI: −0.60–0.03; p = 0.03). Furthermore, caffeine increased the frequency of positive game actions during simulated volleyball matches (SMD: 0.84; 95% CI: 0.26–1.43; p < 0.01). Conclusions: Caffeine supplementation enhances physical performance and volleyball-specific actions during competition, supporting its role as an effective ergogenic aid for volleyball players. Full article
(This article belongs to the Special Issue Caffeine Intake for Human Health and Exercise Performance)
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11 pages, 222 KiB  
Article
Sports Supplement Use in Road Cycling: A Comparative Analysis by Sex and Competitive Category
by Jesús García-Durán, David Romero-García, José Miguel Martínez-Sanz, José Antonio González-Jurado and Antonio Jesús Sánchez-Oliver
Sports 2025, 13(4), 122; https://doi.org/10.3390/sports13040122 - 16 Apr 2025
Viewed by 850
Abstract
This study analyzes and compares sports supplement (SS) consumption among federated road cyclists, considering sex and competition category. The aim is to identify key factors influencing SS use and provide insights for developing nutritional strategies in cycling. A cross-sectional, descriptive study was conducted, [...] Read more.
This study analyzes and compares sports supplement (SS) consumption among federated road cyclists, considering sex and competition category. The aim is to identify key factors influencing SS use and provide insights for developing nutritional strategies in cycling. A cross-sectional, descriptive study was conducted, involving 1503 cyclists (1231 men and 272 women). Data were collected through a validated questionnaire assessing anthropometric data, training habits, SS consumption patterns, and sources of information. Results indicate that 64.3% of cyclists currently use SS. Women reported a significantly higher consumption rate (88.2%) compared to men (59.1%), although men had a higher average SS intake than women (8.28 ± 9.36 vs. 6.76 ± 5.96). Additionally, SS use decreased with age and competition level, with elite cyclists showing the highest prevalence (76.3%) and master 50 the lowest (58.4%). Group A supplements (scientifically supported) were the most frequently used, while Group C supplements (limited evidence) and Group D substances (prohibited) were more commonly consumed by men. Findings highlight significant differences in SS consumption based on sex and competition level, with elite cyclists and women reporting higher prevalence. However, men reported a higher average number of SS consumed. The study underscores the need for targeted nutritional education, particularly among master cyclists, to promote evidence-based SS use and minimize the risks of ineffective or unsafe supplementation. Future research should explore the long-term effects of SS consumption in cycling and the effectiveness of educational interventions for safe and optimized supplementation practices. Full article
(This article belongs to the Special Issue Strategies to Improve Modifiable Factors of Athletic Success)
25 pages, 1609 KiB  
Review
Ergonutrition Supplementation and Recovery in Water Polo: A Systematic Review
by Álvaro Miguel-Ortega, Josu Barrenetxea-Garcia, María-Azucena Rodríguez-Rodrigo, Enrique García-Ordóñez, Juan Mielgo-Ayuso and Julio Calleja-González
Nutrients 2025, 17(8), 1319; https://doi.org/10.3390/nu17081319 - 10 Apr 2025
Viewed by 1013
Abstract
Background: Water polo (WP) is a high-intensity team sport that requires a combination of physical endurance, muscular strength, speed, and specific technical skills. Due to the demanding and prolonged nature of this sport, adequate and balanced nutrition plays a fundamental role in athletes’ [...] Read more.
Background: Water polo (WP) is a high-intensity team sport that requires a combination of physical endurance, muscular strength, speed, and specific technical skills. Due to the demanding and prolonged nature of this sport, adequate and balanced nutrition plays a fundamental role in athletes’ performance, recovery, and overall health maintenance. Objectives: We aimed to compile all available information on the importance of ergonutrition and supplementation in the recovery of WP players. This will help in understanding this sport’s specific challenges and requirements, enabling players and coaches to design more effective recovery plans to optimize performance, achieve goals, and successfully cope with intense training and competition. Method: English-language publications were searched in databases such as Web of Science, Scopus, SciELO Citation Index, Medline (PubMed), KCI Korean Journal Database, and Current Contents Connect using a series of keywords such as WP, nutrition, recovery, and ergogenic aids individually or in combination. Results: In the field of ergonutritional recovery in WP, certain supplements such as whey protein, beta-alanine, L-arginine, spirulina, and copper can be beneficial for improving performance and recovery. In some cases, WP athletes may consider using ergogenic supplements to further improve their performance and recovery process. However, it is important to bear in mind that any supplement should be carefully evaluated under the supervision of a health professional or a sports nutritionist, as some supplements may present side effects or unwanted interactions. Conclusions: Adequate ergogenic nutrition adapted to the needs of WP players is essential not only to optimize their athletic performance but also to ensure effective recovery and maintain their long-term health and general well-being. The application of these strategies should be evidence-based and tailored to the individual needs of the players and the specific demands of the sport. Future experimental research that can confirm our results is essential. Full article
(This article belongs to the Special Issue New Strategies in Sport Nutrition: Enhancing Exercise Performance)
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22 pages, 2872 KiB  
Article
Caffeine Combined with Excitatory Neuromodulation Based on Transcranial Direct Current Stimulation (tDCS) Enhances Performance in a Time-Trial CrossFit® Workout: A Randomized, Placebo-Controlled, Double-Blind Study
by Alberto Souza Sá Filho, Thiago Albernaz-Silva, Pedro Augusto Inacio, Vicente Aprigliano, Iransé Oliveira-Silva, Gaspar R. Chiappa, Rodolfo P. Vieira, Antônio Sérgio Nakao de Aguiar, Raphael Martins Cunha, James Oluwagbamigbe Fajemiroye and Marcelo Magalhães Sales
Nutrients 2025, 17(7), 1261; https://doi.org/10.3390/nu17071261 - 3 Apr 2025
Viewed by 1731
Abstract
Background: Caffeine (CAF) and transcranial direct current stimulation (tDCS) are ergogenic strategies with potential benefits for performance, yet their combined effects remain underexplored, particularly in high-intensity functional training contexts such as CrossFit®. This randomized, double-blind, placebo-controlled crossover study aimed to investigate [...] Read more.
Background: Caffeine (CAF) and transcranial direct current stimulation (tDCS) are ergogenic strategies with potential benefits for performance, yet their combined effects remain underexplored, particularly in high-intensity functional training contexts such as CrossFit®. This randomized, double-blind, placebo-controlled crossover study aimed to investigate the impact of tDCS, with and without CAF, on performance time in the Clean & Jerk (C&J) during the benchmark WOD GRACE among competitive CrossFit® athletes. Secondarily, we aimed to compare the RPE across the different experimental conditions, as well as to establish the relationship between personal record (PR) values adjusted for body mass and the execution time of the WOD GRACE, considering different athletes’ classification levels (RX Elite and RX Intermediate). Methods: Twenty participants completed four experimental conditions: CAF ingestion (400 mg) combined with anodal tDCS (CAF + a-tDCS), CAF with Sham tDCS (CAF + Sham-tDCS), placebo (PLA) with a-tDCS (PLA + a-tDCS), and PLA with Sham tDCS (PLA + Sham-tDCS). Results: The results indicated that the combination of CAF + a-tDCS significantly improved performance, reducing execution time (205.5 ± 58.0 s) compared to CAF + Sham-tDCS (218.3 ± 61.2 s; p = 0.034), PLA + a-tDCS (231.7 ± 64.1 s; p = 0.012), and PLA + Sham-tDCS (240.9 ± 66.4 s; p = 0.002). However, no significant differences were observed between CAF + Sham-tDCS and PLA + a-tDCS (p = 0.690), CAF + Sham-tDCS and PLA + Sham-tDCS (p = 0.352), or PLA + a-tDCS and PLA + Sham-tDCS (p = 0.595). Conclusions: The responder analysis revealed that 45% of participants improved performance with isolated tDCS, while 60% responded positively to CAF. No significant differences were found in RPE scores among conditions (p = 0.145). Additionally, no correlations were identified between PR values adjusted for body mass and execution time in both RX Elite (r = 0.265; p = 0.526) and RX Intermediate (r = 0.049; p = 0.901) groups, nor between training experience and performance across interventions. These findings suggest that tDCS, when combined with CAF, may serve as an effective ergogenic aid for improving performance in high-intensity functional training, whereas its isolated use does not yield meaningful benefits. Full article
(This article belongs to the Special Issue Caffeine Intake for Human Health and Exercise Performance)
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4 pages, 183 KiB  
Editorial
Nutritional Status and Ergogenic Aids in Performance During Exercise and Sports
by David Varillas-Delgado
Nutrients 2025, 17(7), 1224; https://doi.org/10.3390/nu17071224 - 31 Mar 2025
Cited by 1 | Viewed by 1041
Abstract
The interaction between nutritional status, ergogenic aids, and athletic performance has long been a central focus in sports science [...] Full article
15 pages, 3447 KiB  
Article
Effects of Different Doses of Caffeine on Endurance Exercise Performance in the Heat
by Weiliang Wu, Xifeng Tao, Huiyu Dong, Juan Yang, Yin Liang, Yuanyuan Lv and Laikang Yu
Life 2025, 15(3), 478; https://doi.org/10.3390/life15030478 - 16 Mar 2025
Viewed by 3092
Abstract
This study investigated the effects of different doses of caffeine (3 mg/kg BW and 6 mg/kg BW) on endurance exercise performance in the heat. Seventeen participants completed four randomized, double-blind trials: one in a normal environment (24.6 ± 1.2 °C) and three in [...] Read more.
This study investigated the effects of different doses of caffeine (3 mg/kg BW and 6 mg/kg BW) on endurance exercise performance in the heat. Seventeen participants completed four randomized, double-blind trials: one in a normal environment (24.6 ± 1.2 °C) and three in a hot environment (33.2 ± 1.4 °C), with placebo, 3 mg/kg BW, and 6 mg/kg BW caffeine interventions. Endurance exercise time, cardiorespiratory function, and subjective fatigue perception were measured during incremental cycling tests. The results showed that high temperatures significantly reduced endurance exercise performance in the placebo (p < 0.001) and 3 mg/kg BW (p = 0.003) groups compared to the normal environment, but not in the 6 mg/kg BW group (p = 1.000). Both caffeine doses improved exercise time compared to placebo (3 mg/kg BW, p = 0.005; 6 mg/kg BW, p < 0.001). Caffeine ingestion enhanced pulmonary ventilation (VE), with significant increases in VEpeak (3 mg/kg BW, p = 0.032; 6 mg/kg BW, p = 0.006). Aerobic capacity improved, as evidenced by elevated VO2peak (3 mg/kg BW, p = 0.010; 6 mg/kg BW, p = 0.001) and PetO2 (3 mg/kg BW, p = 0.000; 6 mg/kg BW, p = 0.001). Subjective fatigue perception was significantly reduced only with 6 mg/kg BW caffeine (p = 0.020). In conclusion, caffeine ingestion at 3 mg/kg BW and 6 mg/kg BW effectively counteracts the negative effects of heat stress on endurance exercise performance by improving respiratory function, enhancing aerobic capacity, and reducing subjective fatigue. The 6 mg/kg BW dose demonstrated superior effects, making it a potential ergogenic aid for athletes training or competing in the heat. Full article
(This article belongs to the Section Physiology and Pathology)
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15 pages, 1128 KiB  
Article
The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue Conditions: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial
by Daniel Marcos-Frutos, Žiga Leban, Zhaoqian Li, Xing Zhang, Paula M. Lara, Carlos Alix-Fages, Pablo Jiménez-Martínez, Nadia Zebboudji, Annabelle Caillet, Beatriz Redondo, Jesús Vera, Danica Janicijevic and Amador García-Ramos
Nutrients 2025, 17(6), 940; https://doi.org/10.3390/nu17060940 - 7 Mar 2025
Cited by 1 | Viewed by 13655
Abstract
Objectives: This study aimed to explore the effects of four days of Rhodiola Rosea (RR) supplementation on bench-press and bench-pull exercises under resting or mental fatigue conditions in young healthy individuals. Methods: Eighteen participants (seven women) visited the laboratory on five [...] Read more.
Objectives: This study aimed to explore the effects of four days of Rhodiola Rosea (RR) supplementation on bench-press and bench-pull exercises under resting or mental fatigue conditions in young healthy individuals. Methods: Eighteen participants (seven women) visited the laboratory on five occasions separated by 7 days—one preliminary session and four experimental sessions. In the preliminary session, participants were familiarised with the Stroop and Multiple Object Tracking tests, after which their one-repetition maximum loads for bench presses and bench pulls were determined. The four experimental sessions had the same protocol, differing only in the supplement (RR or placebo) and mental task conditions (Stroop test or control video). Participants were assigned randomly and counterbalanced to each experimental condition: (I) RR and Stroop test, (II) RR and control video, (III) placebo and Stroop test, and (IV) placebo and control video. Results: The main findings indicate that RR supplementation has trivial-to-small effects in terms of mental fatigue, visuo-cognitive processing, or perceived exertion. However, RR was significantly superior to placebo on strength performance in the control video condition during some sets, as it increased the number of repetitions performed in the bench press and the fastest velocity in the bench pull. Out of 52 comparisons, 17 small effect sizes were observed, with 14 favouring RR and 3 favouring placebo, with the remaining differences being trivial. Conclusions: These results suggest that short-term RR supplementation is safe and provides its main ergogenic effects on physical performance rather than in visuo-cognitive or mental outcomes. Full article
(This article belongs to the Special Issue Nutritional Supports for Sport Performance)
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