Search Results (1,159)

A comprehensive techno-economic assessment was undertaken to determine the viability of bioethanol production from sugarcane bagasse in Thailand through organosolv fractionation, incorporating three distinct catalytic systems: sulfuric acid, formic acid, and sodium methoxide. Rigorous process simulations were executed using Aspen Plus, facilitating the derivation of detailed mass and energy balances, which served as the foundational input for downstream cost modeling. Economic performance metrics, including the total annualized cost and minimum ethanol selling price, were systematically quantified for each scenario. Among the evaluated configurations, the formic acid-catalyzed organosolv system exhibited superior techno-economic attributes, achieving the lowest unit production costs of 1.14 USD/L for ethanol and 1.84 USD/kg for lignin, corresponding to an estimated ethanol selling price of approximately 1.14 USD/L. This favorable outcome was attained with only moderate capital intensity, indicating a well-balanced trade-off between operational efficiency and investment burden. Conversely, the sodium methoxide-based process configuration imposed the highest economic burden, with a TAC of 15.27 million USD/year, culminating in a markedly elevated MESP of 5.49 USD/kg (approximately 4.33 USD/L). The sulfuric acid-driven system demonstrated effective delignification performance. Sensitivity analysis revealed that reagent procurement costs exert the greatest impact on TAC variation, highlighting chemical expenditure as the key economic driver. These findings emphasize the critical role of solvent choice, catalytic performance, and process integration in improving the cost-efficiency of lignocellulosic ethanol production. Among the examined options, the formic acid-based organosolv process stands out as the most economically viable for large-scale implementation within Thailand’s bioeconomy. Full article

Introduction: This study evaluated the performance of automated dual-energy computed tomography (DECT)-based quantification of perfusion defects (PDs) in acute pulmonary embolism and examined its correlation with clinical parameters. Methods: We retrospectively analyzed data from 171 patients treated for moderate-to-severe acute pulmonary embolism, who underwent DECT imaging at two separate time points. PDs were quantified using a fully automated AI-based segmentation method that relied exclusively on iodine perfusion maps. This was compared with a semi-automatic clinician-guided segmentation, where radiologists manually adjusted thresholds to eliminate artifacts. Clinical variables including the Miller obstruction score, right-to-left ventricular diameter ratio, oxygen saturation, and patient-reported symptoms were also collected. Results: The semiautomatic method demonstrated stronger correlations with embolic burden (Miller score; r = 0.4, p < 0.001 at follow-up) and a negative correlation with oxygen saturation (r = −0.2, p = 0.04). In contrast, the fully automated AI-based quantification consistently produced lower PD values and demonstrated weaker associations with clinical parameters. Conclusions: Semiautomatic quantification of PDs currently provides superior accuracy and clinical relevance for evaluating lung PDs in acute pulmonary embolism. Future multimodal AI models that incorporate both anatomical and clinical data may further enhance diagnostic precision. Full article

The exponential growth of lithium-ion battery consumption has amplified the urgency of identifying sustainable and economically viable recycling solutions. This study proposes an integrated decision-making framework based on the T-Spherical Fuzzy Einstein Interaction Aggregator DEMATEL-CoCoSo approach to comprehensively evaluate and rank battery recycling technologies under uncertainty. Ten key evaluation criteria—encompassing environmental, economic, and technological dimensions—were identified through expert consultation and literature synthesis. The T-Spherical Fuzzy DEMATEL method was first applied to analyze the causal interdependencies among criteria and determine their relative weights, revealing that environmental drivers such as energy consumption, greenhouse gas emissions, and waste generation exert the most systemic influence. Subsequently, six recycling alternatives were assessed and ranked using the CoCoSo method enhanced by Einstein-based aggregation, which captured the complex interactions present in the experts’ evaluations and assessments. Results indicate that Direct Recycling is the most favorable option, followed by the Hydrometallurgical and Bioleaching methods, while Pyrometallurgical Recycling ranked lowest due to its high energy demands and environmental burden. The proposed hybrid model effectively handles linguistic uncertainty, expert variability, and interdependent evaluation structures, offering a robust decision-support tool for sustainable technology selection in the circular battery economy. The framework is adaptable to other domains requiring structured expert-based evaluations under fuzzy environments. Full article

Background and Objectives: Multiple sclerosis (MS) is a chronic immune-mediated neurological disorder that primarily affects young adults and is frequently accompanied by psychiatric comorbidities such as depression and anxiety, both of which significantly diminish patients’ quality of life (QoL). This study investigated the effect of two oral disease-modifying therapies (DMTs), fingolimod and cladribine, on mental health and QoL in patients with relapsing-remitting MS (RRMS). The aim of the study was to compare levels of depression, anxiety, and health-related quality of life (HRQoL) in RRMS patients treated with fingolimod or cladribine, and to evaluate their associations with clinical and radiological parameters. Materials and Methods: Eighty RRMS patients aged 18 to 50 years with Expanded Disability Status Scale (EDSS) scores of 3.0 or less, no recent disease relapse, and no history of antidepressant use were enrolled. Forty patients were treated with fingolimod and forty with cladribine. Depression and anxiety were assessed using the Hamilton Depression Rating Scale (HDRS) and the Hamilton Anxiety Rating Scale (HARS). QoL was evaluated using the Multiple Sclerosis QoL-54 (MSQOL-54) instrument. Additional clinical data, including MRI-based lesion burden, EDSS scores, age, disease duration, and occupational status, were collected. Results: No statistically significant differences were observed between the two groups regarding HDRS and HARS scores (p > 0.05). However, patients treated with fingolimod had significantly higher scores in the Energy/Fatigue subdomain (7.55 ± 2.02 vs. 6.56 ± 2.57, p = 0.046) and Composite Mental Health (CMH) score (64.73 ± 15.01 vs. 56.00 ± 18.93, p = 0.029) compared to those treated with cladribine. No significant differences were found in the independent items of the MSQOL-54. A negative correlation was identified between total lesion load and QoL scores. Conclusions: Although fingolimod and cladribine exert comparable effects on depression and anxiety levels, fingolimod may be associated with better mental health outcomes and reduced fatigue in RRMS patients. Furthermore, lesion burden and clinical parameters such as age and EDSS score may independently influence QoL, regardless of the DMT used. Full article

With the support of the dual-carbon strategy and related policies, China’s offshore wind power has experienced rapid development. However, constrained by the inherent intermittency and volatility of wind power, large-scale expansion poses significant challenges to grid integration and exacerbates government fiscal burdens. To address these critical issues, this paper proposes a multi-market coupling trading model integrating energy storage-equipped offshore wind power into electricity–carbon–green certificate markets for large-scale grid networks. Firstly, a day-ahead electricity market optimization model that incorporates energy storage is established to maximize power revenue by coordinating offshore wind power generation, thermal power dispatch, and energy storage charging/discharging strategies. Subsequently, carbon market and green certificate market optimization models are developed to quantify Chinese Certified Emission Reduction (CCER) volume, carbon quotas, carbon emissions, market revenues, green certificate quantities, pricing mechanisms, and associated economic benefits. To validate the model’s effectiveness, a gradient ascent-optimized game-theoretic model and a double auction mechanism are introduced as benchmark comparisons. The simulation results demonstrate that the proposed model increases market revenues by 17.13% and 36.18%, respectively, compared to the two benchmark models. It not only improves wind power penetration and comprehensive profitability but also effectively alleviates government subsidy pressures through coordinated carbon–green certificate trading mechanisms. Full article

Hydrogen production is increasingly vital for global decarbonization but remains a water- and energy-intensive process, especially in arid regions. Despite growing attention to its climate benefits, limited research has addressed the environmental impacts of water sourcing. This study employs a life cycle assessment (LCA) approach to evaluate three water supply strategies for hydrogen production: (1) seawater desalination without brine treatment (BT), (2) desalination with partial BT, and (3) freshwater purification. Scenarios are modeled for the United Arab Emirates (UAE), Australia, and Spain, representing diverse electricity mixes and water stress conditions. Both electrolysis and steam methane reforming (SMR) are evaluated as hydrogen production methods. Results show that desalination scenarios contribute substantially to human health and ecosystem impacts due to high energy use and brine discharge. Although partial BT aims to reduce direct marine discharge impacts, its substantial energy demand can offset these benefits by increasing other environmental burdens, such as marine eutrophication, especially in regions reliant on carbon-intensive electricity grids. Freshwater scenarios offer lower environmental impact overall but raise water availability concerns. Across all regions, feedwater for SMR shows nearly 50% lower impacts than for electrolysis. This study focuses solely on the environmental impacts associated with water sourcing and treatment for hydrogen production, excluding the downstream impacts of the hydrogen generation process itself. This study highlights the trade-offs between water sourcing, brine treatment, and freshwater purification for hydrogen production, offering insights for optimizing sustainable hydrogen systems in water-stressed regions. Full article

The production of iron and steel plays a significant role in the anthropogenic carbon footprint, accounting for 7% of global GHG emissions. In the context of CO₂ mitigation, the steelmaking industry is looking to potentially replace traditional carbon-based ironmaking processes with hydrogen-based direct reduction of iron ore in shaft furnaces. Before industrialization, detailed modeling and parametric studies were needed to determine the proper operating parameters of this promising technology. The modeling approach selected here was to complement REDUCTOR, a detailed finite-volume model of the shaft furnace, which can simulate the gas and solid flows, heat transfers and reaction kinetics throughout the reactor, with an extension that describes the whole gas circuit of the direct reduction plant, including the top gas recycling set up and the fresh hydrogen production. Innovative strategies (such as the redirection of part of the bustle gas to a cooling inlet, the use of high nitrogen content in the gas, and the introduction of a hot solid burden) were investigated, and their effects on furnace operation (gas utilization degree and total energy consumption) were studied with a constant metallization target of 94%. It has also been demonstrated that complete metallization can be achieved at little expense. These strategies can improve the thermochemical state of the furnace and lead to different energy requirements. Full article

Advances in plaque imaging have transformed cardiovascular diagnostics through detailed characterization of atherosclerotic plaques beyond traditional stenosis assessment. This review outlines the clinical applications of varying modalities, including dual-layer spectral CT, photon-counting CT, dual-energy CT, and CT-derived fractional flow reserve (CT-FFR). These technologies offer improved spatial resolution, tissue differentiation, and functional assessment of coronary lesions. Additionally, artificial intelligence has emerged as a powerful tool to automate plaque detection, quantify burden, and refine risk prediction. Collectively, these innovations provide a more comprehensive approach to coronary artery disease evaluation and support personalized management strategies. Full article

The global shift towards the use of renewable energy is essential to ensure sustainable development, and geothermal energy stands out as a suitable option that can support various cascading projects. Spent geothermal water (SGW) requires proper treatment to ensure that it does not become an environmental burden. Typically, companies often face the dilemma of choosing between discharging spent geothermal water (SGW) into surface waters or injecting it into rock masses, and the economic and environmental impacts of the decision made determines the feasibility of geothermal plant development. In this study, we aimed to comprehensively assess the technical, economic, and environmental feasibility of SGW injection into rock masses. To this end, we employed a comprehensive analytical approach using the Chochołów GT-1 geothermal injection borehole in Poland as a reference case. We also performed drilling and hydrogeological testing, characterized rock samples in the laboratory, and corrected hydrodynamic parameters for thermal lift effects to ensure accurate aquifer characterization. The results obtained highlight the importance of correcting hydrogeological parameters for thermal effects, which if neglected can lead to a significant overestimation of the calculated hydrogeological parameters. Based on our analysis, we developed a framework for assessing SGW injection feasibility that integrates detailed hydrogeological and geotechnical analyses with environmental risk assessment to ensure sustainable geothermal resource exploitation. This framework should be mandatory for planning new geothermal power plants or complexes worldwide. Our results also emphasize the need for adequate SGW management so as to ensure that the benefits of using a renewable and zero-emission resource, such as geothermal energy, are not compromised by the low absorption capacity of rock masses or adverse environmental effects. Full article

Circulating fluidized bed fly ash (CFBFA) stockpiles release alkaline dust, high-pH leachate, and secondary CO₂/SO₂—an environmental burden that exceeds 240 Mt yr⁻¹ in China alone. Yet, barely 25% is recycled, because the high f-CaO/SO₃ contents destabilize conventional cementitious products. Here, we presents a pressurized flue gas heat curing (FHC) route to bridge this scientific deficit, converting up to 85 wt% CFBFA into structural lightweight gravel. The gypsum dosage was optimized, and a 1:16 (gypsum/CFBFA) ratio delivered the best compromise between early ettringite nucleation and CO₂-uptake capacity, yielding the highest overall quality. The optimal mix reaches 9.13 MPa 28-day crushing strength, 4.27% in situ CO₂ uptake, 1.75 g cm⁻³ bulk density, and 3.59% water absorption. Multi-technique analyses (SEM, XRD, FTIR, TG-DTG, and MIP) show that FHC rapidly consumes expansive phases, suppresses undesirable granular-ettringite formation, and produces a dense calcite/needle-AFt skeleton. The FHC-treated CFBFA composite gravel demonstrates 30.43% higher crushing strength than JTG/TF20-2015 standards, accompanied by a water absorption rate 28.2% lower than recent studies. Its superior strength and durability highlight its potential as a low-carbon lightweight aggregate for structural engineering. A life-cycle inventory gives a cradle-to-gate energy demand of 1128 MJ t⁻¹ and a process GWP of 226 kg CO₂-eq t⁻¹. Consequently, higher point-source emissions paired with immediate mineral sequestration translate into a low overall climate footprint and eliminate the need for CFBFA landfilling. Full article

This study conducts a comprehensive systematic review of the economic impact of Digital Twin (DT) technology within the Architecture, Engineering, and Construction (AEC) industry, following the PRISMA methodology. While DT adoption has been accelerated by advancements in Building Information Modelling (BIM), the Internet of Things (IoT), and data analytics, significant challenges persist—most notably, high initial investment costs and integration complexities. Synthesising the literature from 2016 onwards, this review identifies sector-specific barriers, regulatory burdens, and a lack of standardisation as key factors constituting DT implementation costs. Despite these hurdles, DTs demonstrate strong potential for enhancing construction productivity, optimising lifecycle asset management, and enabling predictive maintenance, ultimately reducing operational expenditures and improving long-term financial performance. Case studies reveal cost efficiencies achieved through DTs in modular construction, energy optimisation, and infrastructure management. However, limited financial resources and digital skills continue to constrain the uptake across the sector, with various extents of impact. This paper calls for the development of unified standards, innovative public–private funding mechanisms, and strategic collaborations to unlock and utilise DTs’ full economic value. It also recommends that future research explore theoretical frameworks addressing governance, data infrastructure, and digital equity—particularly through conceptualising DT-related data as public assets or collective goods in the context of smart cities and networked infrastructure systems. Full article

Blasting is one of the most widely used and cost-effective techniques for rock excavation and fragmentation in open-pit mining, particularly for large-scale operations. However, repeated or poorly controlled blasting can generate excessive ground vibrations that threaten slope stability by causing structural damage, fracturing of the rock mass, and potential failure. Evaluating the effects of blast-induced vibrations is essential to ensure safe and sustainable mining operations. This study investigates the impact of blasting-induced vibrations on slope stability at the Saindak Copper-Gold Open-Pit Mine in Pakistan. A comprehensive dataset was compiled, including field-monitored ground vibration measurements—specifically peak particle velocity (PPV) and key blast design parameters such as spacing (S), burden (B), stemming length (SL), maximum charge per delay (MCPD), and distance from the blast point (D). Geomechanical properties of slope-forming rock units were validated through laboratory testing. Slope stability was analyzed using pseudo-static limit equilibrium methods (LEMs) based on the Mohr–Coulomb failure criterion, employing four approaches: Fellenius, Janbu, Bishop, and Spencer. Pearson and Spearman correlation analyses quantified the influence of blasting parameters on slope behavior, and sensitivity analysis determined the cumulative distribution of slope failure and dynamic response under increasing seismic loads. FoS values were calculated for both east and west pit slopes under static and dynamic conditions. Among all methods, Spencer consistently yielded the highest FoS values. Under static conditions, FoS was 1.502 for the east slope and 1.254 for the west. Under dynamic loading, FoS declined to 1.308 and 1.102, reductions of 12.9% and 11.3%, respectively, as calculated using the Spencer method. The east slope exhibited greater stability due to its gentler angle. Correlation analysis revealed that burden had a significant negative impact (r = −0.81) on stability. Sensitivity analysis showed that stability deteriorates notably when PPV exceeds 10.9 mm/s. Although daily blasting did not critically compromise stability, the west slope showed greater vulnerability, underscoring the need for stricter control of blasting energy to mitigate vibration-induced instability and promote long-term operational sustainability. Full article

The quality of a grid-injected current in LCL-type grid-connected inverters (GCI) degrades under ultra-weak grid conditions, posing serious challenges to the stability of the GCI system. For this purpose, the sliding mode control (SMC) approach has been utilized to integrate DC energy seamlessly into the grid. The control performance of a GCI equipped with an LCL filter is greatly reduced when it is operating in a power grid with varying impedance and fluctuating grid voltages, which may result in poor current quality and possible instability in the system. A non-singular double integral terminal sliding mode (DIT-SMC) control is presented in this paper for a three-phase GCI with an LCL filter. The proposed method is presented in the α, β frame of reference without adopting an active or passive damping approach, reducing the computational burden. MATLAB/Simulink Version R2023b is leveraged to simulate the mathematical model of the proposed control system. The capability of the DIT-SMC method is validated through the OPAL-RT hardware-in-loop (HIL) platform. The effectiveness of the proposed method is first compared with SMC and integral terminal SMC, and then the DIT-SMC method is rigorously analyzed under resonance frequency events, grid impedance variation, and grid voltage distortions. It is demonstrated by the experimental results that the proposed control is highly effective in delivering a high-quality current into the grid, in spite of the simultaneous occurrence of power grid impedance variations in 6 mH and large voltage distortions. Full article

In light of the ongoing discussion concerning the energy transition of the heating sector, primarily focused on district heating and shaped by heating corporations towards an incremental transformation, an alternative direction for the energy transition of the heating sector towards electroheating—a breakthrough transformation—is presented in this paper, along with a justification of its rationale. Arguments “for” and “against” both transformation paths are provided. Analyses of the costs of transforming district heating systems along both trajectories are conducted. The opportunities of a breakthrough transformation are characterized. An alternative approach to the energy transformation of district heating systems will provoke resistance and opposition from representatives of institutions operating within the current model. Transforming the existing heating model without changing its structure will burden society with high transformation costs through demands for government guarantees to cover these expenses. The analysis presented in this paper shows that these costs can be significantly reduced if the approach to the generation and distribution of district heat is changed. Full article