Search Results (2,544)

Transformers are critical assets for power system reliability, as they connect different voltage levels across generation, transmission, and distribution. Their failure can lead to significant impacts on multiple aspects. Given the aging transformer fleet, supply chain challenges, and constrained investment capacity, the adoption of risk-based strategies is essential to support long-term maintenance planning and investment. This paper proposes a multicriteria framework to assess the probability and impact of transformer failure, enabling a more comprehensive and data-driven risk evaluation. The method was applied to a sample fleet, enabling the identification and prioritization of the most critical units through a risk plot. The framework enhances asset management by identifying critical units within a transformer fleet, promoting efficiency, reliability, and long-term planning based on objective risk indicators. Full article

Breast-conserving surgery followed by external beam Radiotherapy (RT) is a standard approach for early-stage Breast Cancer (BC). This retrospective study aims to determine the risk of RT-induced lung cancer for both standard and hypofractionated treatments. Fifty-eight Sicilian women treated at Humanitas Istituto Clinico Catanese (Misterbianco, Italy) between 2015 and 2021 with standard fractionated 3D-CRT (50 Gy in 2 Gy/fraction) were included. All treatment plans were designed using a hypofractionated schedule (42.56 Gy in 2.66 Gy/fraction). An Eclipse™ plug-in script was developed using the Eclipse Scripting Application Programming Interface (ESAPI) to extract patient and treatment data from the Treatment Planning System and compute Organ At Risk (OAR) volume, Organ Equivalent Dose (OED), Excess Absolute Risk (EAR), and Lifetime Attributable Risk (LAR) using the Schneider Mechanistic Model and reference data from regional populations, A-bomb survivors, and patients with Hodgkin’s Disease (HD). The OED distributions exhibited a statistically significant shift toward higher values in standard fractionated plans (p < 0.01, one-tailed paired Student’s t-test), leading to increased EAR and LAR. These results indicate that hypofractionated treatment may lower the risk of radiation-induced lung cancer. The feasibility of a priori risk estimation was evaluated by integrating the script into the TPS, allowing rapid comparison of SF and HF plans during planning. Full article

Distributed photovoltaic (PV) generation is increasingly important for urban energy systems amid global climate change and the shift to renewable energy. Traditional PV deployment prioritizes maximizing energy output, often neglecting electricity price variability caused by time-of-use tariffs. This study develops a high-resolution planning and economic assessment model for building-integrated PV (BIPV) systems, incorporating hourly electricity real-time market prices, solar geometry, and submeter building spatial data. Wuhan (30.60° N, 114.05° E) serves as the case study to evaluate optimal PV placement and tilt angles on rooftops and façades, focusing on maximizing economic returns rather than energy production alone. The results indicate that adjusting rooftop PV tilt from a maximum generation angle (30°) to a maximum revenue angle (15°) slightly lowers generation but increases revenue, with west-facing orientations further improving returns by aligning output with peak electricity prices. For façades, south-facing panels yielded the highest output, while north-facing panels with tilt angles above 20° also showed significant potential. Façade PV systems demonstrated substantially higher generation potential—about 5 to 15 times that of rooftop PV systems under certain conditions. This model provides a spatially detailed, market-responsive framework supporting sustainable urban energy planning, quantifying economic and environmental benefits, and aligning with integrated approaches to urban sustainability. Full article

Under the “dual carbon” goals and rapid clean energy development, power grids face challenges including rapid load growth, uneven power flow distribution, and limited transmission capacity. This paper proposes a novel FACTS device with fault tolerance and switchable topology that maintains power flow control over multiple lines during N-1 faults, enhancing grid safety and economy. The paper establishes a steady-state mathematical model based on additional virtual nodes and provides power flow calculation methods to accurately reflect the device’s control characteristics. An entropy-weighted TOPSIS method was employed to establish a quantitative evaluation system for assessing the grid performance improvement after FACTS device integration. To address interaction issues among multiple flexible devices, an optimization planning model considering th3e coordinated effects of UPFC and VSC-HVDC was constructed. Multi-objective particle swarm optimization obtained Pareto solution sets, combined with the evaluation system, to determine the optimal configuration schemes. Considering wind power uncertainty and fault risks, we propose a system-level coordinated operation strategy. This strategy constructs probabilistic risk indicators and introduces topology switching control constraints. Using particle swarm optimization, it achieves a balance between safety and economic objectives. Simulation results in the Jiangsu power grid scenarios demonstrated significant advantages in enhancing the transmission capacity, optimizing the power flow distribution, and ensuring system security. Full article

We propose a dynamic monitoring and precision fertilization decision system for agricultural soil nutrients, integrating UAV remote sensing and GIS technologies to address the limitations of traditional soil nutrient assessment methods. The proposed method combines multi-source data fusion, including hyperspectral and multispectral UAV imagery with ground sensor data, to achieve high-resolution spatial and spectral analysis of soil nutrients. Real-time data processing algorithms enable rapid updates of soil nutrient status, while a time-series dynamic model captures seasonal variations and crop growth stage influences, improving prediction accuracy (RMSE reductions of 43–70% for nitrogen, phosphorus, and potassium compared to conventional laboratory-based methods and satellite NDVI approaches). The experimental validation compared the proposed system against two conventional approaches: (1) laboratory soil testing with standardized fertilization recommendations and (2) satellite NDVI-based fertilization. Field trials across three distinct agroecological zones demonstrated that the proposed system reduced fertilizer inputs by 18–27% while increasing crop yields by 4–11%, outperforming both conventional methods. Furthermore, an intelligent fertilization decision model generates tailored fertilization plans by analyzing real-time soil conditions, crop demands, and climate factors, with continuous learning enhancing its precision over time. The system also incorporates GIS-based visualization tools, providing intuitive spatial representations of nutrient distributions and interactive functionalities for detailed insights. Our approach significantly advances precision agriculture by automating the entire workflow from data collection to decision-making, reducing resource waste and optimizing crop yields. The integration of UAV remote sensing, dynamic modeling, and machine learning distinguishes this work from conventional static systems, offering a scalable and adaptive framework for sustainable farming practices. Full article

Background/Objectives: This study aims to present a structured clinical workflow for offline adaptive Biology-guided Radiotherapy (BgRT) using the RefleXion X1 PET-linac system, addressing challenges introduced by inter-treatment anatomical and biological changes. Methods: We propose a decision tree offline adaptation framework based on real-time assessments of Activity Concentration (AC), Normalized Target Signal (NTS), and bounded dose-volume histogram (bDVH%) metrics. Three offline strategies were developed: (1) preemptive adaptation for minor changes, (2) partial re-simulation for moderate changes, and (3) full re-simulation for major anatomical or metabolic alterations. Two clinical cases demonstrating strategies 1 and 2 are presented. Results: The preemptive adaptation strategy was applied in a case with early tumor shrinkage, maintaining delivery parameters within acceptable limits while updating contours and dose distribution. In the partial re-Simulation case, significant changes in PET signal necessitated a same-day PET functional modeling session and plan re-optimization, effectively restoring safe deliverability. Both cases showed reduced target volumes and improved OAR sparing without additional patient visits or tracer injections. Conclusions: Offline adaptive workflows for BgRT provide practical solutions to address inter-fractional changes in tumor structure and function. These strategies can help maintain the safety and accuracy of BgRT delivery and support clinical adoption of PET-guided radiotherapy, paving the way for future online adaptive capabilities. Full article

Multiple-resolution modeling (MRM) has emerged as a foundational paradigm in modern simulation, enabling the integration of models with varying levels of granularity to address complex and evolving operational demands. By supporting seamless transitions between high-resolution and low-resolution representations, MRM facilitates scalability and interoperability, particularly within distributed simulation environments such as military command and control systems. This paper provides a structured review and comparative analysis of prominent MRM methodologies, including multi-resolution entities (MRE), agent-based modeling (from a federation viewpoint), hybrid frameworks, and the novel MR mode, synchronizing resolution transitions with time advancement and interaction management. Each approach is evaluated across critical dimensions such as consistency, computational efficiency, flexibility, and integration with legacy systems. Emphasis is placed on the applicability of MRM in distributed military simulations, where it enables dynamic interplay between strategic-level planning and tactical-level execution, supporting real-time decision-making, mission rehearsal, and scenario-based training. The paper also explores emerging trends involving artificial intelligence (AI) and large language models (LLMs) as enablers for adaptive resolution management and automated model interoperability. Full article

To address the challenges posed by the instability of renewable energy output and load fluctuations on grid operations and to support the low-carbon sustainable development of the energy system, this paper integrates artificial intelligence technology to establish an economic stability dispatch framework for distributed resource aggregators. A phased multi-contract collaborative scheduling model oriented toward sustainable development is proposed. Through intelligent algorithms, the model dynamically optimises decisions across the day-ahead and intraday phases: During the day-ahead scheduling phase, intelligent algorithms predict load demand and energy output, and combine with elastic performance-based response contracts to construct a user-side electricity consumption behaviour intelligent control model. Under the premise of ensuring user comfort, the model generates a 24 h scheduling plan with the objectives of minimising operational costs and efficiently integrating renewable energy. In the intraday scheduling phase, a rolling optimisation mechanism is used to activate energy storage capacity contracts and dynamic frequency stability contracts in real time based on day-ahead prediction deviations. This efficiently coordinates the intelligent frequency regulation strategies of energy storage devices and electric vehicle aggregators to quickly mitigate power fluctuations and achieve coordinated control of primary and secondary frequency regulation. Case study results indicate that the intelligent optimisation-driven multi-contract scheduling model significantly improves system operational efficiency and stability, reduces system operational costs by 30.49%, and decreases power purchase fluctuations by 12.41%, providing a feasible path for constructing a low-carbon, resilient grid under high renewable energy penetration. Full article

Africa’s rapid urbanization often exceeds the capacity of governments to provide essential services and infrastructure, exacerbating structural inequalities and exposing vulnerable populations to serious health risks. This paper examines the case of Douala, Cameroon, to demonstrate that health inequities in African cities are not simply the result of urban growth but are shaped by spatial inequities, historical legacies, and systemic exclusion. Disadvantaged neighborhoods are particularly impacted, becoming epicenters of health crises. Using a mixed-methods approach combining spatial analysis, household surveys and interviews, the study identifies three key findings: (1) Healthcare services in Douala are unevenly distributed and dominated by private providers, which limits access for low-income residents. (2) Inadequate infrastructure and environmental risks in informal settlements lead to a higher disease burden and an overflow of demand into better-equipped districts, which overwhelms public health centers across the city. (3) This structural mismatch fuels widespread reliance on informal and unregulated care practices. This study positions Douala as a microcosm of broader public health challenges in rapidly urbanizing African cities. It highlights the need for integrated urban planning and health system reforms that address spatial inequalities, strengthen public health infrastructure, and prioritize equity—key principles for achieving the third Sustainable Development Goal (ensuring good health and well-being for all residents) in sub-Saharan Africa. Full article

Background/Objective: In the pursuit of identifying novel therapeutic agents against breast cancer, a major priority is finding agents that effectively and safely inhibit the signaling pathways sustaining cancer cells. To better focus research efforts in validating such candidates, this in silico study assessed the pharmacokinetic profiles, thermodynamics, and binding affinity of chlorogenic acid and cinnamaldehyde with the upstream mediators of the Akt pathway implicated in breast cancer cells. Methods: Various software and online tools were used to conduct molecular docking of the small molecules with the proteins PI3K, Akt, and PDK1, and to examine their absorption, distribution, metabolism, elimination, and toxicity (ADMET) profile. Results: The results show strong binding energy (all within the range of those of FDA-approved drugs) and thermostability between the compounds and the proteins. The phytochemicals were predicted to have moderate oral bioavailability and tissue distribution, and were identified as substrates of drug metabolizing enzymes, but not deactivated. Conclusion: Although these predictive data warrant confirmation in a biological system, they suggest that the compounds have good pharmacokinetics and are strong inhibitors of the Akt pathway, with great potential to shut down breast cancer cell invasion and migration. These data also inform more efficient experimental designs for our planned in vivo studies. Full article

How to promote sustainable development and deal with the actual development demands in economic transformation through land-use planning is crucial for local governments. The urban sustainable development mainly relies on creativity and talents in the digital era, and talents are increasingly attracted by local people-oriented land use. However, the current planning ideology remains at meeting corporate and people’s basic needs rather than specific needs of talents, especially the increasingly emerging digital creatives. To promote the talent agglomeration and sustainable development through land planning, this paper uses micro-celebrities on Bilibili, an influential creative content creation platform among young people in China, as an example to study the geographical distribution of digital creative talents and its relationship with urban amenities by constructing an index system of urban amenities, comprising natural, leisure, infrastructure, and social and institutional amenities. The concept of borrowed amenities is introduced to examine the effects of amenities of surrounding cities. This study demonstrates that micro-celebrities show a stronger preference for amenities compared with other skilled talents. Meanwhile, social and institutional amenities are most crucial. Furthermore, urban leisure represented by green spaces and consumption spaces is also attractive. At the regional scale, with prefecture-level cities as units, the local talents agglomeration is also influenced by the borrowed amenities in the context of regional integration. It indicates that the local land use should consider the characteristics of the surrounding cities. This study provides strategic inspiration that a happy and sustainable city should first be people-oriented and provide sufficient space for consumption, entertainment, and interaction. Full article

Changes in habitat suitability are critical indicators of the ecological impacts of climate change. Syndiclis Hook. f., a rare and endangered genus endemic to montane limestone and cloud forest ecosystems in China, holds considerable ecological and economic value. However, knowledge of its current distribution and the key environmental factors influencing its habitat suitability remains limited. In this study, we employed the MaxEnt model, integrated with geographic information systems (ArcGIS), to predict the potential distribution of Syndiclis under current and future climate scenarios, identify dominant bioclimatic drivers, and assess temporal and spatial shifts in habitat patterns. We also analyzed spatial displacement of habitat centroids to explore potential migration pathways. The model demonstrated excellent performance (AUC = 0.988), with current suitable habitats primarily located in Hainan, Taiwan, Southeastern Yunnan, and along the Yunnan–Guangxi border. Temperature seasonality (bio7) emerged as the most important predictor (67.00%), followed by precipitation of the driest quarter (bio17, 14.90%), while soil factors played a relatively minor role. Under future climate projections, Hainan and Taiwan are expected to serve as stable climatic refugia, whereas the overall suitable habitat area is projected to decline significantly. Combined with topographic constraints, population decline, and limited dispersal ability, these changes elevate the risk of extinction for Syndiclis in the wild. Landscape pattern analysis revealed increased habitat fragmentation under warming conditions, with only 4.08% of suitable areas currently under effective protection. We recommend prioritizing conservation efforts in regions with habitat contraction (e.g., Guangxi and Yunnan) and stable refugia (e.g., Hainan and Taiwan). Conservation strategies should integrate targeted in situ and ex situ actions, guided by dominant environmental variables and projected migration routes, to ensure the long-term persistence of Syndiclis populations and support evidence-based conservation planning. Full article

Losses from floods and the wide range of impacts have been at the forefront of hazard-triggered disasters in China. Affected by large-scale human activities and the environmental evolution, China’s defense flood situation is undergoing significant changes. This paper constructs a comprehensive flood disaster risk assessment model through systematic analysis of four key factors—hazard (H), exposure (E), susceptibility/sensitivity (S), and disaster prevention capabilities (C)—and establishes an evaluation index system. Using the Analytic Hierarchy Process (AHP), we determined indicator weights and quantified flood risk via the following formula R = H × E × V × C. After we applied this model to 16 towns in coastal Zhejiang Province, the results reveal three distinct risk tiers: low (R < 0.04), medium (0.04 ≤ R ≤ 0.1), and high (R > 0.1). High-risk areas (e.g., Longxi and Shitang towns) are primarily constrained by natural hazards and socioeconomic vulnerability, while low-risk towns benefit from a robust disaster mitigation capacity. Risk typology analysis further classifies towns into natural, social–structural, capacity-driven, or mixed profiles, providing granular insights for targeted flood management. The spatial risk distribution offers a scientific basis for optimizing flood control planning and resource allocation in the district. Full article

Cruciferous vegetables are popular in Asian dishes. However, striped flea beetles prefer to feed on leaves, which can damage the appearance of crops and reduce their economic value. Due to the lack of pest monitoring, the occurrence of pests is often irregular and unpredictable. Regular and quantitative spraying of pesticides for pest control is an alternative method. Nevertheless, this requires manual execution and is inefficient. This paper presents a system powered by solar energy, utilizing batteries and supercapacitors for energy storage to support the implementation of edge AI devices in outdoor environments. Raspberry Pi is utilized for artificial intelligence image recognition and the Internet of Things (IoT). YOLOv5 is implemented on the edge device, Raspberry Pi, for detecting striped flea beetles, and StyleGAN3 is also utilized for data augmentation in the proposed system. The recognition accuracy reaches 85.4%, and the results are transmitted to the server through a 4G network. The experimental results indicate that the system can operate effectively for an extended period. This system enhances sustainability and reliability and greatly improves the practicality of deploying smart pest detection technology in remote or resource-limited agricultural areas. In subsequent applications, drones can plan routes for pesticide spraying based on the distribution of pests. Full article

This study investigates the accessibility of public healthcare services in Olsztyn County, a major urban center in the Warmia and Mazury region of Poland. The aim was to develop a methodological framework using Geographic Information System (GIS) tools and spatial data to assess the local availability of healthcare infrastructure. The analysis included key facilities such as hospitals, clinics, pharmacies, and specialized outpatient services. A spatial accessibility indicator was constructed to evaluate and compare access levels across municipalities. The results show a clear disparity between urban and rural areas, with significantly better access in cities. Several rural municipalities were found to have limited or no access to essential healthcare services. These findings highlight the uneven spatial distribution of medical infrastructure and point to the need for targeted strategies to improve service availability in underserved areas. The proposed methodological approach may support future studies and inform local and regional planning aimed at reducing healthcare inequalities and improving access for all residents, regardless of their location. This research contributes to the growing body of evidence emphasizing the role of spatial analysis in assessing public service accessibility and supports the development of more equitable healthcare systems at the local level. Full article